[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"glaucoma-suspect\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:glaucoma-suspect":54},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,40,64,97],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":21,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":28,"lastUpdatePostDateStruct":29,"startDateStruct":32,"completionDateStruct":34,"leadSponsor":36,"locationsCount":39},"100615880","automated-applanation-tonometry---updated-100615880",false,"NCT07298356","Automated Applanation Tonometry - Updated","Criteria:\n\nInclusion Criteria:\n\n* Presenting for a routine eye exam\n* ≥ 18 years of age\n* Able and willing to give consent\n\nExclusion Criteria:\n\n* History of corneal scarring\n* Active infection of the eye\n* Ocular surface trauma or infection","ALL","18 Years",{"count":18,"type":19},200,"ESTIMATED","INTERVENTIONAL",[22],"NA","Goldmann Applanation Tonometry (GAT) is considered the clinical gold standard for eye pressure measurements and yet it is known to be a subjective measurement with limited repeatability and limited portability. Another clinical standard for checking eye pressure is known as the pneumotonometer. This method is more objective but not portable. The purpose of this study is to develop new methods of measuring eye pressure that are more objective, reproducible and portable. In this study, the investigators will be comparing the eye pressure measurements using 2 investigational methods to GAT and pneuumotonometer.",[25,26],"Glaucoma","Glaucoma, Suspect","RECRUITING","2026-03-04",{"date":30,"type":31},"2026-03-06","ACTUAL",{"date":33,"type":31},"2026-03-02",{"date":35,"type":19},"2026-12-29",{"name":37,"class":38},"Duke University","OTHER",1,{"id":41,"slug":42,"hasResults":11,"nctId":43,"briefTitle":44,"officialTitle":44,"acronym":4,"eligibilityCriteria":45,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":46,"targetDuration":4,"studyType":20,"phases":48,"briefSummary":50,"conditions":51,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":55,"lastUpdatePostDateStruct":56,"startDateStruct":58,"completionDateStruct":60,"leadSponsor":62,"locationsCount":39},"100609676","phase-4-biomarkers-of-ocular-surface-damage-in-the-setting-of-topical-ocular-hypotensive-medication-use-100609676","NCT07217678","Biomarkers of Ocular Surface Damage in the Setting of Topical Ocular Hypotensive Medication Use","Inclusion Criteria:\n\n* Eye with open-angle glaucoma or suspected of open-angle glaucoma\n* Pseudophakic in eye of interest with Shafer grading ≥3\n* ≤ 3 daily applications of topical glaucoma medications for ≥6 months (of which one is a nightly preserved PGA)\n* Good adherence to medication regimen - screening questions to be asked of potential subject:\n* In the last month, what percentage of the time would you estimate missing the application of drops? (Must be ≤20%)\n* When was the last administration? (Last dose must have been within last 24 hours)\n* Presence of punctate epithelial erosions in the cornea (NEI scale \\> 3)\n\nExclusion Criteria:\n\n* Retinal disease (e.g., wet age-related macular degeneration, proliferative diabetic retinopathy, central retinal vein occlusion)\n* Use of topical or systemic immunosuppressor or immunomodulator drug (e.g., steroids, cyclosporine, lifitegrast, or antihistamines)\n* Use of preservative-free hypotensive medications\n* Any clinical contraindications to receiving intracameral bimatoprost implantation\n* History of recurrent conjunctivitis (e.g., allergic or atopic conjunctivitis)\n* History of partial or full corneal transplant\n* History of ophthalmic surgery (intraocular or tarsus-involving oculoplastic procedures) within last 6 months\n* History of subconjunctival glaucoma surgery (i.e., trabeculectomy, aqueous shunt, Xen implant) within last 6 months",{"count":47,"type":19},20,[49],"PHASE4","The objective of this study is to evaluate whether reduction in topical medication with the injection of a sustained release capsule (Durysta) leads to a reduction in ocular surface inflammation, indicated by levels of caspase-1, an inflammatory biomarker.",[25,52,53,54],"Open-Angle Glaucoma","Ocular Hypertension","Glaucoma Suspect","2026-03-03",{"date":57,"type":31},"2026-03-05",{"date":59,"type":31},"2026-02-09",{"date":61,"type":19},"2028-01-31",{"name":63,"class":38},"University of Miami",{"id":65,"slug":66,"hasResults":11,"nctId":67,"briefTitle":68,"officialTitle":68,"acronym":4,"eligibilityCriteria":69,"healthyVolunteers":70,"sex":15,"minAge":71,"maxAge":4,"enrollmentInfo":72,"targetDuration":4,"studyType":20,"phases":74,"briefSummary":75,"conditions":76,"keywords":79,"overallStatus":87,"whyStopped":4,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":39},"100515508","know-your-pressures-nyc-100515508","NCT05992415","Know Your Pressures NYC","Inclusion Criteria:\n\n* Individuals age 40 and older.\n* Living independently in an affordable housing development.\n* Have a cell phone that can receive and send text messages (SMS).\n\nExclusion Criteria:\n\n* Self-reported terminal illness with life expectancy less than 1 year.\n* Inability to provide informed consent due to dementia or other reasons.",true,"40 Years",{"count":73,"type":19},7085,[22],"Dr. Lisa A. Hark (PI and Study Chair) and an interdisciplinary team have designed \"Know Your Pressures NYC\" to conduct blood pressure (BP)\u002Fglaucoma screenings in adults age 40+ to identify undiagnosed and\u002For uncontrolled hypertension and\u002For glaucoma\u002Fsuspect. For the purpose of this study, individuals will be identified as glaucoma suspects if they have elevated intraocular pressure (IOP) or have features of glaucoma optic neuropathy, as assessed by optical coherence tomography (OCT) and fundus\u002Foptic nerve photographs, as interpreted by the masked Reading Center.",[25,77,26,78],"Hypertension","Elevated Blood Pressure",[80,81,82,83,84,85,86],"Blood pressure (BP)","Intraocular pressure (IOP)","Optic nerve imaging","Fundus photography","Blood pressure and glaucoma screening","Optical coherence tomography (OCT)","Hypertension (HTN)","NOT_YET_RECRUITING","2025-09-17",{"date":90,"type":31},"2025-09-22",{"date":92,"type":19},"2026-07-01",{"date":94,"type":19},"2031-06-30",{"name":96,"class":38},"Columbia University",{"id":98,"slug":99,"hasResults":11,"nctId":100,"briefTitle":101,"officialTitle":101,"acronym":4,"eligibilityCriteria":102,"healthyVolunteers":70,"sex":15,"minAge":103,"maxAge":104,"enrollmentInfo":105,"targetDuration":4,"studyType":20,"phases":106,"briefSummary":107,"conditions":108,"keywords":112,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":116,"lastUpdatePostDateStruct":117,"startDateStruct":119,"completionDateStruct":121,"leadSponsor":123,"locationsCount":39},"100221201","a-more-engaging-visual-field-test-to-increase-use-and-reliability-in-pediatrics-100221201","NCT02157025","A More Engaging Visual Field Test to Increase Use and Reliability in Pediatrics","Inclusion Criteria:\n\n* Ages 5-8\n* Seen previously in the clinics at Nova Southeastern University's The Eye Care Institute with a diagnosis for glaucoma suspect or optic nerve abnormalities\n* Able and willing to complete VF testing at 2 study visits about a week apart\n* Provide informed consent\n\nExclusion Criteria:\n\n* History of having previously completed a VF test using Humphrey static perimetry\n* Inability to understand study or communicate responses (cognitive impairment)\n* Unable to understand, read and speak English fluently","5 Years","8 Years",{"count":47,"type":19},[22],"The majority of young children do not think that visual field (VF) testing of peripheral vision is similar to a game; therefore, it is not surprising that they have difficulty maintaining attention during VF testing and thus the test reliability suffers as a consequence. Poor VF reliability has been a longstanding, major issue since it leads to an increased number of tests and\u002For longer duration of time needed to determine when there are true vision losses. Providers are less likely to obtain VF tests in children since the results are of doubtful value and challenging to interpret when they are inconsistent. Effectively this means that children with untreated, slowly progressive eye diseases may go undiagnosed and incur greater visual losses. The investigators aim to create a prototype device that the investigators hypothesize will make VF testing more engaging for young children, thus increasing their attention and consistency of their responses to the test stimuli, which in turn should improve VF reliability. The components include a microdisplay video screen (1.5\" diameter) as the fixation target (instead of the standard LED light) displaying video clips of popular cartoon characters, and audio clips of impersonated cartoon character voices presented by the test operator to provide instructional feedback based on the child's performance during testing. Improved VF reliability from the investigators intervention would translate to improved diagnosis and care for young childrens' peripheral vision loss through widespread implementation of the investigators innovative, affordable and readily adoptable system at eye care providers' offices.",[26,109,110,111],"Optic Nerve Hypoplasia and Abnormalities of the Central Nervous System","Congenital Coloboma of the Optic Nerve","Optic Nerve Head Pits, Bilateral Congenital",[113,114,115],"Humphrey visual fields","perimetry","pediatrics","2025-09-03",{"date":118,"type":31},"2025-09-10",{"date":120,"type":31},"2015-02",{"date":122,"type":19},"2027-12",{"name":124,"class":38},"Nova Southeastern University"]