[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"guided-surgery-accuracy\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:guided-surgery-accuracy":31},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,57,87],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":34,"overallStatus":44,"whyStopped":4,"lastUpdateSubmitDate":45,"lastUpdatePostDateStruct":46,"startDateStruct":49,"completionDateStruct":51,"leadSponsor":53,"locationsCount":56},"100641124","do-immediate-digital-workflows-increase-patient-value-100641124",false,"NCT07656597","Do Immediate Digital Workflows Increase Patient Value?","Do Immediate Digital Workflows Increase Patient Value? A Patient-Reported Outcome Measure-Based Randomized Controlled Trial Comparing Immediate Versus Delayed Digital Posterior Implant Workflows","ITI PROM RCT","Inclusion Criteria:\n\n* Adults aged 18 years or older.\n* Indication for single implant therapy in a posterior premolar or molar extraction site.\n* Good oral hygiene with FMPS ≤20%.\n* Controlled periodontitis according to protocol definition.\n* At least one natural tooth adjacent to the implant site and presence of an antagonist tooth.\n* Ability to comply with study procedures and provide written informed consent.\n* Adequate bone volume for immediate or delayed placement.\n* Extraction site suitable for centrally positioned, prosthetically driven implant placement using straight prosthetic components.\n* Ability to achieve 3-4 mm circumferential implant engagement in native bone along the planned implant axis while maintaining safety distance from vital structures.\n* For molar sites, septal bone classified as Smith \\& Tarnow Type A or Type B, including cases requiring closed sinus floor elevation.\n* Post-extraction socket presenting as a contained or partially contained defect with at least three relatively intact socket walls and no individual socket wall vertical defect \\>5 mm.\n* No facial soft-tissue dehiscence or mucogingival defect associated with buccal bone dehiscence.\n\nExclusion Criteria:\n\n* • Known or suspected poor compliance, alcohol abuse, or substance abuse.\n\n  * Systemic or local contraindications to implant surgery.\n  * History of head\u002Fneck radiotherapy or recent malignancy within 5 years.\n  * Use of medications affecting bone metabolism.\n  * Bisphosphonate use within the past 5 years.\n  * Uncontrolled periodontal disease.\n  * Heavy smoking (\\>10 cigarettes\u002Fday).\n  * Pregnancy or lactation.\n  * Teeth with periapical lesions \\>5 mm in greatest diameter, or sockets demonstrating a large cortical perforation \\>5 mm in greatest dimension on CBCT.","ALL","18 Years",{"count":20,"type":21},50,"ESTIMATED","INTERVENTIONAL",[24],"NA","This two-center randomized controlled trial will evaluate whether an immediate digital posterior implant workflow provides greater patient-defined value than a delayed digital workflow in adults requiring single posterior implant rehabilitation. Participants will be randomized 1:1 to immediate implant placement at the time of tooth extraction or to delayed implant placement after approximately 16 weeks of healing following extraction and ridge preservation as indicated. The primary endpoint is oral health-related quality of life assessed longitudinally using the OHIP-14 questionnaire and analyzed as the model-based mean score averaged across the active treatment phase from baseline through definitive crown delivery. Secondary outcomes include workflow-related patient experience, chairside time, number of visits, postoperative pain, buccal contour changes based on intraoral scan-derived volumetric analysis, radiographic marginal bone level changes, implant survival, clinical peri-implant parameters, technical complications, esthetic outcomes, accuracy of guided implant placement, and clinician-reported workflow outcomes.",[27,28,29,30,31,32,33],"Dental Implant","Implant Therapy","Immediate Dental Implant Placement","Delayed Implant","Guided Surgery Accuracy","Patient-Reported Outcomes (PRO)","Single Tooth Dental Implant",[27,35,36,37,38,39,40,41,42,43],"immediate implant placement","delayed implant placement","digital workflow","guided surgery","patient-reported outcomes","OHIP-14","posterior implant rehabilitation","chairside time","volumetric analysis","NOT_YET_RECRUITING","2026-06-15",{"date":47,"type":48},"2026-06-18","ACTUAL",{"date":50,"type":21},"2026-08-03",{"date":52,"type":21},"2028-10-31",{"name":54,"class":55},"Heinrich-Heine University, Duesseldorf","OTHER",2,{"id":58,"slug":59,"hasResults":11,"nctId":60,"briefTitle":61,"officialTitle":62,"acronym":4,"eligibilityCriteria":63,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":64,"enrollmentInfo":65,"targetDuration":4,"studyType":22,"phases":67,"briefSummary":68,"conditions":69,"keywords":72,"overallStatus":44,"whyStopped":4,"lastUpdateSubmitDate":78,"lastUpdatePostDateStruct":79,"startDateStruct":81,"completionDateStruct":83,"leadSponsor":85,"locationsCount":4},"100618939","computer-guided-split-thickness-versus-full-thickness-flap-buccal-bone-lid-approach-in-hard-mandibular-pathosis-100618939","NCT07338136","Computer Guided Split Thickness Versus Full Thickness Flap Buccal Bone Lid Approach in Hard Mandibular Pathosis","Computer Guided Split Thickness Versus Full Thickness Flap Buccal Bone Lid Approach in Hard Mandibular Pathosis: Randomized Control Trial RCT","Inclusion criteria:\n\n* No sex predilection.\n* Age: 18 to 40\n* mandibular intra-bony hard pathosis with a diameter ≥1cm with a buccal cortex thickness ≥1mm\n\nExclusion criteria:\n\n* Systemic or local disease\u002F condition that could affect bone healing\n* Diabetics\n* patients on systemic corticosteroid\n* chemotherapy\n* radiotherapy","40 Years",{"count":66,"type":21},26,[24],"* Full thickness Buccal bone lid approach is well known and well reported technique with a superiority on preserving bone volume and better bone healing especially when done using piezoelectrical devices when compared to conventional technique for management of mandibular pathosis, however periosteum disturbance have a negative role regarding vascularity and bone healing, by comparing the split thickness VS full thickness flap design with buccal bone lid approach, this study will highlight if the periosteum preserved attached to the lid improve the healing on mandibular bony pathosis.\n* Aim of the study:\n\ndetermine the effect of split thickness flap vs full thickness flap using a guided bone lid in hard mandibular pathosis in term of bone healing.",[70,71,31],"Mandibular Diseases","Guided Surgery",[73,74,75,76,77],"buccal bone lid","split thickness flap","computer guided surgery","mandibular pathosis","impacted tooth","2026-01-13",{"date":80,"type":48},"2026-01-15",{"date":82,"type":21},"2026-02",{"date":84,"type":21},"2027-04",{"name":86,"class":55},"Cairo University",{"id":88,"slug":89,"hasResults":11,"nctId":90,"briefTitle":91,"officialTitle":92,"acronym":4,"eligibilityCriteria":93,"healthyVolunteers":11,"sex":17,"minAge":94,"maxAge":4,"enrollmentInfo":95,"targetDuration":4,"studyType":22,"phases":97,"briefSummary":98,"conditions":99,"keywords":100,"overallStatus":106,"whyStopped":4,"lastUpdateSubmitDate":107,"lastUpdatePostDateStruct":108,"startDateStruct":110,"completionDateStruct":112,"leadSponsor":114,"locationsCount":116},"100579107","accuracy-of-static-guided-implant-surgery-3d-printed-vs-milled-surgical-guides-100579107","NCT06819995","Accuracy of Static Guided Implant Surgery: 3D-printed vs Milled Surgical Guides","Accuracy of Static Guided Implant Surgery: 3D-printed vs Milled Surgical Guides, a Randomized Clinical Trial","Inclusion Criteria:\n\n* Male or female patients with one to four missing teeth, where dental implants are planned and where a tooth-supported or tooth-mucosal supported surgical guides can be fabricated. Free-ended situations will be allowed.\n* Edentulous sites with at least 3 months of healing after tooth extraction.\n* Staged hard and soft tissue augmentation will be permitted. In cases of previous bone augmentation (e.g. staged horizontal bone regeneration or lateral sinus lift), a minimum healing period of 6 months should be respected. In cases of previous soft tissue augmentation procedures, a minimum healing period of 2 months should be respected. Simultaneous close sinus lift procedures will be allowed when there is a minimum posterior bone height of 6 mm.\n* Implants should be surrounded by at least 1.5 mm of bone.\n* Periodontally healthy patients or with stable periodontal conditions after periodontal therapy. Periodontitis will be defined according to the EFP-AAP 2017 World Workshop Classification (Papapanou PN, Sanz M, et al., 2018): interdental CAL is detectable at ≥2 non-adjacent teeth or buccal or oral CAL ≥3 mm with pocketing ≥3 mm is detectable at ≥2 teeth, but the observed CAL cannot be ascribed to non-periodontitis-related causes such as 1) gingival recession of traumatic origin; 2) dental caries extending in the cervical area of the tooth; 3) the presence of CAL on the distal aspect of a second molar and associated with malposition or extraction of a third molar, 4) an endodontic lesion draining through the marginal periodontium; and 5) the occurrence of a vertical root fracture.\n* Aged 21 years and over and able to sign an informed consent form.\n* Enough available bone assessed on CBCT to place Klockner Vega implants of diameters ranging from 3.5 to 4.5 mm and lengths between 8 and 12 mm.\n\nExclusion Criteria:\n\n1. Systemic\n\n   * Completely edentulous patients or patients requiring mucosal- or bone-supported surgical guides.\n   * Compromised general health (ASA IV-VI patients).\n   * Systemic diseases which could influence the outcome of therapy (uncontrolled diabetes mellitus, bone disorders, etc.).\n   * Pregnant or nursing women.\n   * Chronic use of corticosteroids, nonsteroidal anti-inflammatory drugs (NSAID), or immune-modulator drugs (any type and dose).\n   * Patients who need medications that affect bone metabolism (bisphosphonates, any type and dose).\n   * Chronic diseases of the oral mucosa.\n   * Smokers of \\>10 cigarettes\u002Fday.\n   * \\>25% plaque index at the time of re-evaluation after non-surgical periodontal therapy and OHI\n   * Unable to attend all study visits.\n   * Need of simultaneous bone augmentation after implant placement to treat dehiscence and fenestration type defects or to augment bone contour (\\\u003C1.5 mm of bone all around the implant circumference).\n2. During surgery\n\n   * Lack of primary stability assessed by hand testing after implant placement.\n   * Less of 2 mm of keratinized mucosa, both at the lingual and buccal sites.\n   * Lack of guide adjustment verified through the fitting windows.","21 Years",{"count":96,"type":21},48,[24],"Dear Patient,\n\nYou are invited to participate in a clinical study. To understand the study, please carefully review the following information. If you have any questions, feel free to ask the dentist leading the study.\n\nDental implants are an effective, long-term solution for replacing missing teeth. They replace the root of a lost or unsalvageable tooth, supporting a crown or prosthesis to restore function and aesthetics. Proper placement is crucial for implants to function and last. Guided implant surgery is a technique that improves precision using customized surgical guides created from patient records, such as radiographs and scans. These guides act as templates to ensure accurate implant placement, optimizing functionality, aesthetics, and minimizing complications.\n\nThere are two main methods for fabricating surgical guides: milling, which cuts material into shape, and 3D printing, which builds material layer by layer. This study aims to evaluate the differences in accuracy and long-term outcomes between implants placed using guides created by these two methods. Both clinical results (appearance and function) and radiographic results (bone integration) will be assessed to determine the best method for guide fabrication.\n\nYou were selected for this study because you require dental implant rehabilitation. After clinical and radiographic evaluations, we determined you are a suitable candidate for implant placement to restore your dental function and aesthetics.\n\nIf you choose to participate, the following steps will be taken:\n\n1. A thorough examination of your dental health, including radiographs and photographs.\n2. Planning and guided surgery performed at the Postgraduate Program in Periodontics.\n3. Random assignment to receive either a 3D-printed or milled surgical guide. This assignment will be computer-generated and remain unknown until the study concludes.\n4. Surgery under local anesthesia, lasting 1-2 hours, followed by suture removal after 7 days and follow-ups at 2 and 3 weeks to monitor healing.\n5. At 3 months, clinical and radiographic evaluations will be performed, and digital impressions will be taken to assess differences between planned and final implant positions. The impressions will also be used to fabricate your final prosthesis, which will be placed approximately one month later.\n6. Follow-ups at 6 and 12 months after prosthesis placement will assess implant stability and overall outcomes. The study will conclude after this final evaluation.\n\nParticipation involves certain risks:\n\n* Anesthesia-related risks, such as allergic reactions, prolonged numbness, or local tissue damage.\n* Surgical risks, including pain, swelling, bleeding, infection, temporary or permanent numbness, and damage to adjacent teeth or roots.\n* Implant failure, either during initial bone integration or later, requiring additional treatment or replanning.\n* Risks of material failure, such as fractures or loosening of prosthetic components.\n\nBy participating, you will avoid costs for the implants, healing abutments, and surgical guides (approximate savings: €800-€1,200). However, you will be responsible for surgery (€60), prosthetic components (€250 each), and final restorations (€350 per crown). Participation also includes close monitoring of your implants for one year, allowing for early detection and management of complications at no cost.\n\nParticipation is voluntary. If you decide not to participate, it will not affect your care. You may also withdraw from the study at any time without penalty, although clinical follow-ups are recommended to monitor your treatment outcomes.\n\nYour data will be handled anonymously and securely, in compliance with data protection laws (e.g., Spain's Organic Law 3\u002F2018). Data will be used solely for research purposes and not for commercial gain. Identifiable information will not be published, and your rights to access, correct, or delete your data will be upheld.\n\nIf you have questions, you may contact the research team by phone or email. You may also consult your dentist or the Ethics Committee. A copy of this document is available for your records.\n\nThank you for considering participation in this study.",[27,31],[101,102,103,104,105],"Dental implant","Guided surgery","Surgical guide","3D printing","Milling","RECRUITING","2025-03-25",{"date":109,"type":48},"2025-03-26",{"date":111,"type":48},"2025-02-15",{"date":113,"type":21},"2026-12-31",{"name":115,"class":55},"Universidad Complutense de Madrid",1]