[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"hand-function-in-healthy-individuals\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:hand-function-in-healthy-individuals":32},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":25,"briefSummary":27,"conditions":28,"keywords":34,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":41,"lastUpdatePostDateStruct":42,"startDateStruct":45,"completionDateStruct":47,"leadSponsor":49,"locationsCount":5},"100598223","effects-of-thumb-manipulation-on-hand-grip-strength-function-and-sensation-100598223",false,"NCT07068698","Effects of Thumb Manipulation on Hand Grip Strength, Function, and Sensation","The Effects of Thumb Manipulation on Hand Grip Strength, Hand Function, and Sensory Parameters","THUMBFUN","Inclusion Criteria:\n\n* Aged between 18 and 50\n* Willing to participate in the study\n* Have signed the informed consent form\n* Able to use verbal and written communication skills\n\nExclusion Criteria:\n\n* Having contraindications that may prevent manipulation\n* Having a history of congenital or acquired orthopedic or neurological conditions affecting the upper extremity\n* Having a history of rheumatological diseases\n* Having a history of trauma or surgery affecting the upper extremity",true,"ALL","18 Years","50 Years",{"count":22,"type":23},60,"ESTIMATED","INTERVENTIONAL",[26],"NA","This randomized controlled study will aim to investigate the effects of thumb manipulation on hand grip strength, function, and sensation in healthy individuals. A total of 60 volunteers aged between 18 and 50 years will be recruited from Ortadağ Special Education and Rehabilitation Center. Participants will be randomly assigned to either a chiropractic manipulation group (n=30) or a control group (n=30), with an equal distribution of males and females in each group. The intervention group will receive thumb manipulation twice weekly for 4 weeks, while the control group will not receive any intervention. Outcome measures will include two-point discrimination (assessed with a discriminator), hand grip strength (measured using a dynamometer), pinch strength (evaluated with a pinch meter), and hand function (measured by the Duruöz Hand Index). Statistical analyses will be performed with a significance level set at p\\\u003C0.05. It is expected that participants in the manipulation group will show greater improvements in all measured parameters compared to the control group, suggesting a positive effect of thumb manipulation on hand-related sensorimotor functions in healthy individuals.",[29,30,31,32,33],"Thumb Manipulation","Hand Grip Strength","Hand Sensory Function","Hand Function in Healthy Individuals","Sensory Function",[35,36,37,38,39],"Thumb manipulation","Chiropractic","Hand grip strength","Hand function","Healthy individuals","NOT_YET_RECRUITING","2025-07-07",{"date":43,"type":44},"2025-07-16","ACTUAL",{"date":46,"type":23},"2025-07-06",{"date":48,"type":23},"2025-09-06",{"name":50,"class":51},"SEFA HAKTAN HATIK","OTHER"]