[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"hand-surgery\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:hand-surgery":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,49,83,104,129],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":31,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":48},"100619237","phase-4-bicarbonate-addition-to-lidocaine-epinephrine-in-surgery-under-walant-100619237",false,"NCT07342010","Bicarbonate Addition to Lidocaine-Epinephrine in Surgery Under WALANT","Evaluation of the Effect of Lidocaine With Adrenaline, With or Without Bicarbonate, on Early Postoperative Recovery in WALLANT-type Outpatient Hand and Foot Surgery: A Prospective, Randomised, Double-blind, Single-centre Non-inferiority Study.","ROPIWA-2","Inclusion Criteria:\n\n* Adults (≥18 years) eligible for ambulatory surgery under WALANT for Hand surgery (including carpal tunnel release, trigger finger release, or Dupuytren's disease surgery) and foot surgery (including hallux valgus or hallux rigidus.)\n* Provision of free and informed consent.\n* Signed informed consent form.\n* Affiliation with or beneficiary of a health insurance system\n\nExclusion Criteria:\n\n* Ischemic vascular disorders, including severe Raynaud's disease, Buerger's disease, or diabetic microangiopathy.\n* Scleroderma.\n* Known allergy to lidocaine or potential cross-reactivity with other amide-type local anesthetics.\n* Severe hepatic impairment.\n* Acute porphyria.\n* Intravascular administration of local anesthesia.\n* Local anesthetic infiltration at the level of the extremities.\n* Coronary artery disease.\n* Ventricular arrhythmias.\n* Severe arterial hypertension.\n* Obstructive cardiomyopathy.\n* Hyperthyroidism.\n* Hypovolemia.\n* Participation in an interventional clinical research study classified as category 1 (RIPH category 1).\n* Ongoing exclusion period related to participation in another clinical study.\n* Legal protection status (guardianship, trusteeship, or judicial protection).\n* Inability to provide informed consent.\n* Inability to receive or understand adequate study information.\n* Pregnancy, labor, or breastfeeding. Women of childbearing potential will undergo a urine pregnancy test prior to inclusion.","ALL","18 Years",{"count":20,"type":21},150,"ESTIMATED","INTERVENTIONAL",[24],"PHASE4","Distal upper limb and distal lower limb surgery performed under local anesthesia using the WALANT technique (Wide Awake Local Anesthesia No Tourniquet) has become standard practice in ambulatory orthopedic surgery. Current infiltration mixtures used by orthopedic surgeons include lidocaine-epinephrine with the addition of 8.4% bicarbonate to reduce injection-related pain and improve analgesia duration. However, the clinical benefit of bicarbonate addition remains insufficiently supported by evidence and may increase preparation complexity and risk, including potential solution crystallization.\n\nThe aim of the ROPIWA-2 trial is to investigate whether omission of bicarbonate from the local infiltration mixture is noninferior to bicarbonate addition with respect to early postoperative quality of recovery on postoperative day 1. We hypothesize that removing bicarbonate does not impair postoperative quality of recovery after ambulatory hand and foot surgery under WALANT. Expected benefits include confirmation of a simpler, ready-to-use anesthetic solution that is easier and safer to use, without reducing patient comfort or recovery. The expected risks are those normally associated with this type of procedure.",[27,28,29,30],"Anesthesia, Local","Hand Surgery","Foot Surgery","Walant Surgery",[32,33,34,35],"lidocaine,","bicarbonates,","Quality of recovery","Walant","NOT_YET_RECRUITING","2026-01-06",{"date":39,"type":40},"2026-01-15","ACTUAL",{"date":42,"type":21},"2026-02-01",{"date":44,"type":21},"2027-02-01",{"name":46,"class":47},"Centre Hospitalier Universitaire de Nīmes","OTHER",1,{"id":50,"slug":51,"hasResults":11,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":4,"eligibilityCriteria":55,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":56,"enrollmentInfo":57,"targetDuration":4,"studyType":22,"phases":59,"briefSummary":61,"conditions":62,"keywords":67,"overallStatus":72,"whyStopped":4,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":48},"100604586","comparison-of-conventional-and-retroclavicular-approaches-for-ultrasound-guided-infraclavicular-brachial-plexus-block-100604586","NCT07151443","Comparison of Conventional and Retroclavicular Approaches for Ultrasound-guided Infraclavicular Brachial Plexus Block","Comparison of Conventional and Retroclavicular Approaches for Ultrasound-guided Infraclavicular Brachial Plexus Block in Obese Patients","Inclusion Criteria:\n\n* Patients 18-80 years of age\n* Those with ASA score II-III\n* Those with a body mass index (BMI) \\>30\n* Patients who are suitable for forearm and hand surgery under regional anesthesia in the operating room\n\nExclusion Criteria:\n\n* Patients who cannot perceive and evaluate pain\n* Patients who want to have surgery under general anesthesia\n* Patients in whom regional anesthesia is contraindicated","80 Years",{"count":58,"type":21},60,[60],"NA","Forearm and hand surgeries are among the most frequently performed surgical interventions both in trauma patients and electively.In these procedures, alternative anesthesia methods such as general anesthesia, regional intravenous anesthesia, regional peripheral nerve blocks and local anesthesia are available.\n\nPeripheral nerve blockade can be used for anesthesia and analgesia.This method allows patients to undergo surgery without general anesthesia and increases patient satisfaction by providing effective analgesia in the postoperative period.\n\nThe aim of this study was to compare the conventional and retroclavicular approaches to infraclavicular block in patients undergoing forearm and hand surgery.",[63,64,65,28,66],"Peripheral Nerve Block","Pain Management","Forearm Surgery","Upper Extremity",[68,69,66,70,71],"Infraclavicular Block","Obesity","Hand surgery","Forearm surgery","RECRUITING","2025-12-08",{"date":75,"type":40},"2025-12-15",{"date":77,"type":40},"2025-09-15",{"date":79,"type":21},"2026-06-25",{"name":81,"class":82},"Ankara Etlik City Hospital","OTHER_GOV",{"id":84,"slug":85,"hasResults":11,"nctId":86,"briefTitle":87,"officialTitle":87,"acronym":88,"eligibilityCriteria":89,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":56,"enrollmentInfo":90,"targetDuration":4,"studyType":22,"phases":92,"briefSummary":93,"conditions":94,"keywords":4,"overallStatus":72,"whyStopped":4,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":98,"completionDateStruct":100,"leadSponsor":102,"locationsCount":48},"100530365","evaluating-the-benefit-of-hypnoanalgesia-versus-neuroleptanalgesia-during-hand-surgery-100530365","NCT06185829","Evaluating the Benefit of Hypnoanalgesia Versus Neuroleptanalgesia During Hand Surgery","HYPNOMAIN","Inclusion Criteria:\n\n* Patients aged between 18 and 80,\n* Patient who has read and signed the consent form for participation in the study after a reflection period (approximately 15 minutes).\n* Patient applying for outpatient hand surgery under LRA, such as upper limb trunk blocks (flexor teno synovectomy or endoscopic carpal tunnel surgery).\n* Patient requiring sedation associated with locoregional anaesthesia\n\nExclusion Criteria:\n\n* Contraindication to locoregional anaesthesia or to one of the sedatives used in the protocol\n* Pregnant or breastfeeding patient or woman of childbearing age without highly effective contraception for the duration of the study (surgically sterile, intrauterine device (\\> 14 days), hormonal contraception (same dose and formulation for at least 6 months), sexual abstinence. Women of childbearing age, i.e. fertile, are considered to be women after menarche and until they become post-menopausal, unless they are permanently infertile or have undergone surgical sterilisation. A post-menopausal state is defined as the absence of menstruation for 12 months without any other medical cause.\n* Patient under court protection, guardianship or curatorship\n* Patient not affiliated to the French social security system\n* Patients unable to understand informed information and\u002For give written informed consent: dementia, psychosis, disturbed consciousness, non-French-speaking patients, etc.",{"count":91,"type":21},64,[60],"This is a single-center, prospective, randomized, open-label study of two parallel groups of patients undergoing hand surgery:\n\nGroup 1: locoregional anesthesia + neuroleptanalgesia Group 2: locoregional anesthesia + hypnoanalgesia Therapeutic benefit is based on VAS assessment of intraoperative anxiety.",[28],"2025-12-02",{"date":97,"type":40},"2025-12-09",{"date":99,"type":40},"2023-10-19",{"date":101,"type":21},"2027-01",{"name":103,"class":47},"GCS Ramsay Santé pour l'Enseignement et la Recherche",{"id":105,"slug":106,"hasResults":11,"nctId":107,"briefTitle":108,"officialTitle":108,"acronym":109,"eligibilityCriteria":110,"healthyVolunteers":11,"sex":17,"minAge":111,"maxAge":112,"enrollmentInfo":113,"targetDuration":4,"studyType":22,"phases":114,"briefSummary":115,"conditions":116,"keywords":4,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":120,"lastUpdatePostDateStruct":121,"startDateStruct":123,"completionDateStruct":125,"leadSponsor":127,"locationsCount":48},"100594079","efficacy-of-laser-acupuncture-on-carpal-tunnel-syndrome-following-hand-flexor-tendon-repair-100594079","NCT07014774","Efficacy of Laser Acupuncture on Carpal Tunnel Syndrome Following Hand Flexor Tendon Repair","LASER","Inclusion Criteria:\n\n* Adults aged 20-40 years who have undergone flexor tendon repair surgery.\n* Patients who have undergone primary or secondary repair of flexor tendons in the hand at zone 4 (zone of carpal tunnel as it often be complicated by postoperative adhesions due to close quarters and synovial sheath of the carpal tunnel) (Fulchignoni C et al., 2020).\n* Surgery occurred within a specific timeframe, often within 6-12 weeks prior to inclusion (Peters SE, Jha B, Ross M., 2021).\n* Patient have clinical and electro diagnostic evidence of CTS.\n* All patients enrolled to the study will have their informed consent.\n\nExclusion Criteria:\n\n* Pre-existing neurological disorders.\n* Systemic illnesses affecting nerve function (e.g., diabetes).\n* Contraindications to laser therapy.\n* Pregnancy or breastfeeding.\n* Active infections or open wounds in the hand or wrist.\n* Previous history of carpal tunnel release surgery or received an injection of steroid for CTS.\n* Previous history of brachial plexus injury or median nerve injury.\n* Other severe neurological or musculoskeletal conditions.\n* Epilepsy or any psychological disorders.\n* Cancer.\n* Spots over the treated points.\n* Pacemaker or implanted devices.","20 Years","40 Years",{"count":58,"type":21},[60],"The purpose of this study is to determine the efficacy of laser acupuncture in alleviating CTS symptoms following flexor tendon repair in the hand.",[117,118,28,119],"Laser Acupuncture","Flexor Tendon Repair","Carpal Tunnel Syndrome (CTS)","2025-06-03",{"date":122,"type":40},"2025-06-11",{"date":124,"type":21},"2025-06-15",{"date":126,"type":21},"2025-10-15",{"name":128,"class":47},"Cairo University",{"id":130,"slug":131,"hasResults":11,"nctId":132,"briefTitle":133,"officialTitle":133,"acronym":4,"eligibilityCriteria":134,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":112,"enrollmentInfo":135,"targetDuration":4,"studyType":22,"phases":137,"briefSummary":138,"conditions":139,"keywords":141,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":144,"lastUpdatePostDateStruct":145,"startDateStruct":147,"completionDateStruct":149,"leadSponsor":151,"locationsCount":4},"100569618","phase-4-comparison-between-effect-of-systemic-fentanyl-infusion-and-fentanyl-added-as-an-adjuvant-to-lidocaine-in-bier-block-for-controlling-pain-in-patients-undergoing-hand-surgeries-100569618","NCT06696586","Comparison Between Effect of Systemic Fentanyl Infusion and Fentanyl Added as An Adjuvant to Lidocaine in Bier Block For Controlling Pain in Patients Undergoing Hand Surgeries","Inclusion Criteria:\n\n* Patients age from 18 years to 40 years\n\n  * Both sex\n  * Patients of the American Society of Anesthesiologists (ASA) physical Status class I and II\n  * BMI less than 40\n\nExclusion Criteria:\n\n* • Patients who refuse to participate in study.\n\n  * Uncooperative patients.\n  * Patient with crush injury\n  * Peripheral vascular, neurological or muscle diseases.\n  * Coagulation disorders that affect the blood's clotting activities e.g.: Hemophilia.\n  * History of hypersensitivity to the drugs being evaluated",{"count":136,"type":21},84,[24],"Injury and deformity of the upper extremity can result in dysfunction to nerves, tendons and bones which can lead to disability and pain.\n\nVarious techniques of regional anesthesia are frequently used for upper extremity surgery. Specifically, intravenous regional anesthesia, the Bier block, is an effective anesthetic technique. This technique, developed by Dr August Bier in 1908, provides complete anesthesia, a bloodless field, and eliminates the need for general anesthesia. However, it was not until the 1960s that this technique was reintroduced and used in upper extremity surgery due to several disadvantages and reports of major complications. Because of the dose of lidocaine and tourniquet time, there is potential for cardiac and neurological complications such as arrhythmias, seizures, and compartment syndrome the aim of this study To evaluate the effect of Systemic Fentanyl Infusion compared to addition of Fentanyl as An Adjuvant to Lidocaine in Bier Block for Controlling Pain in Patients Undergoing Hand Surgeries",[140,28],"Bier Block",[142,143],"Systemic Fentanyl Infusion","Fentanyl Added as An Adjuvant to Lidocaine","2025-04-17",{"date":146,"type":40},"2025-04-18",{"date":148,"type":21},"2025-07-01",{"date":150,"type":21},"2027-01-01",{"name":152,"class":47},"Assiut University"]