[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"hap---hospital-acquired-pneumonia\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:hap---hospital-acquired-pneumonia":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100512453","hapvap-diagnosis-in-critically-ill-septic-patients-using-a-multiplex-pcr-array-100512453",false,"NCT05952648","HAP\u002FVAP Diagnosis in Critically Ill Septic Patients Using a Multiplex PCR Array","HAP\u002FVAP Diagnosis in Critically Ill Septic Patients Using a Multiplex PCR Assay: A Multicenter Randomized Open-Label Trial. THE LIGHTNING STUDY","LIGHTNING","Inclusion Criteria:\n\n* Suspicion of HAP\u002FVAP (clinical\u002Fradiological\u002Flaboratory criteria);\n* Availability to perform tracheal aspirates or broncoalveolar lavage within 1 hour from clinical suspicion\n* Life expectancy ≥ 48 hours\n* Signed written informed consent.\n\nExclusion Criteria:\n\n* Pregnancy,\n* Concomitant participating in other interventional trial\n* Refusal to sign informed consent","ALL","18 Years",{"count":20,"type":21},126,"ESTIMATED","INTERVENTIONAL",[24],"NA","Multicenter, randomized, controlled, open-label trial to assess if semiquantitative multiplex PCR assay, as compared to conventional microbiology, can reduce the percentage of patients without microbiological diagnosis in the first 24 hours from HAP\u002FVAP suspicion, thus allowing early de-escalation.",[27,28],"HAP - Hospital Acquired Pneumonia","VAP - Ventilator Associated Pneumonia","RECRUITING","2025-08-11",{"date":32,"type":33},"2025-08-14","ACTUAL",{"date":35,"type":33},"2024-04-03",{"date":37,"type":21},"2026-04-01",{"name":39,"class":40},"Fondazione Policlinico Universitario Agostino Gemelli IRCCS","OTHER",4]