[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"haplo-identical-donors\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:haplo-identical-donors":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":40},"100572534","clinical-study-of-super-transplantation-in-the-treatment-of-severe--thalassemia-100572534",false,"NCT06734520","Clinical Study of Super Transplantation in the Treatment of Severe β-thalassemia","Inclusion Criteria:\n\n1. Diagnosis of severe β -thalassemia\n2. Age between 7-10 years old, male and female; Weight \\\u003C 40kg\n3. The patient has or does not have an HLA-compatible or semi-compatible donor, but unconditional transplantation or refusal of blood stem cell transplantation; Patients with thalassemia gene therapy without conditions or refusal;\n4. There are fully compatible or incompatible HLA donors, and the physical examination meets the donor conditions;\n5. The patient and family members agree to receive hypertransplant therapy and sign a written informed consent prior to the transplant trial.\n\nExclusion Criteria:\n\n1. Mental patients;\n2. Participants in other drug clinical trials within the past 1 month;\n3. There are no suitable HLA-incompatible donors.\n4. Other researchers decide that it is not suitable to participate in this researcher.","ALL","7 Years","10 Years",{"count":19,"type":20},3,"ESTIMATED","INTERVENTIONAL",[23],"NA","This is a single-arm, open label, phase 1 study in subjects with beta-thalassemia. This study will evaluate the safety and efficacy of preconditioning-free super-transplantation on beta-thalassemia pediatric patients.",[26,27],"Thalassemia Majors (Beta-Thalassemia Major)","Haplo-identical Donors","RECRUITING","2024-12-12",{"date":31,"type":32},"2024-12-16","ACTUAL",{"date":34,"type":32},"2024-10-01",{"date":36,"type":20},"2029-07-01",{"name":38,"class":39},"Guangzhou Women and Children's Medical Center","OTHER",2]