[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"health-literacy\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:health-literacy":29},{"pageToken":4,"total":5,"offset":6,"count":7,"results":8},null,33,0,25,[9,54,80,105,141,177,205,237,266,302,332,358,386,415,450,471,502,528,565,590,630,659,690,714,738],{"id":10,"slug":11,"hasResults":12,"nctId":13,"briefTitle":14,"officialTitle":15,"acronym":4,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":25,"briefSummary":27,"conditions":28,"keywords":32,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":43,"lastUpdatePostDateStruct":44,"startDateStruct":47,"completionDateStruct":49,"leadSponsor":51,"locationsCount":4},"100644166","comparing-digital-and-collaborative-gamified-reinforcement-strategies-for-hpv-literacy-and-retention-among-nursing-students-100644166",false,"NCT07667127","Comparing Digital and Collaborative Gamified Reinforcement Strategies for HPV Literacy and Retention Among Nursing Students","Comparing Digital and Collaborative Gamified Reinforcement Strategies for HPV Literacy and Retention Among Nursing Students: A Randomized Comparative Study","Inclusion Criteria:\n\n* Being a nursing student\n* Voluntary participation\n* Aged 18 years or older\n* Participation in all measurement points\n* Ownership of a smartphone\n* Internet access\n* Having headphones\n\nExclusion Criteria:\n\n* Incomplete data forms\n* Not participating in intervention sessions\n* Absence in posttest or follow-up",true,"ALL","18 Years","45 Years",{"count":22,"type":23},64,"ESTIMATED","INTERVENTIONAL",[26],"NA","This randomized comparative study aims to evaluate the effectiveness of two gamified reinforcement strategies, Gimkit and Escape Room, on human papillomavirus (HPV) literacy, short-term retention, and gameful learning experiences among undergraduate nursing students. Following standardized theoretical instruction on HPV infection, participants will be randomly assigned to either a digital quiz-based gamification intervention (Gimkit) or a collaborative Escape Room activity. Outcomes will be assessed using the Human Papillomavirus Literacy Scale (HPV-LS) and the Gameful Experience Scale (GAMEX) at multiple time points, including baseline, post-theoretical instruction, post-intervention, and one-month follow-up.",[29,30,31],"Health Literacy","Human Papillomavirus (HPV) Infection","Nursing Education",[33,34,35,36,37,38,39,40,41],"HPV literacy","nursing education","educational intervention","gimkit","escape room","Human Papillomavirus","game-based learning","gamification","knowledge retention","NOT_YET_RECRUITING","2026-06-30",{"date":45,"type":46},"2026-07-02","ACTUAL",{"date":48,"type":23},"2026-09-21",{"date":50,"type":23},"2026-10-26",{"name":52,"class":53},"Aydin Adnan Menderes University","OTHER",{"id":55,"slug":56,"hasResults":12,"nctId":57,"briefTitle":58,"officialTitle":59,"acronym":4,"eligibilityCriteria":60,"healthyVolunteers":17,"sex":18,"minAge":61,"maxAge":4,"enrollmentInfo":62,"targetDuration":4,"studyType":64,"phases":4,"briefSummary":65,"conditions":66,"keywords":4,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":79},"100554340","health-literacy-physical-and-cognitive-function-health-related-behaviors-and-quality-of-life-in-copd-100554340","NCT06497816","Health Literacy, Physical and Cognitive Function, Health-related Behaviors, and Quality of Life in COPD","An Investigation of Health Literacy, Physical and Cognitive Function, Health-related Behaviors, and Quality of Life in Chronic Obstructive Pulmonary Disease and Healthy Individuals","Inclusion criteria for the COPD group:\n\n* Being over 40 years old,\n* Diagnosed with COPD and being clinically stable,\n* Being able to cooperate with the tests to be performed,\n* Not having any cardiovascular disease, orthopedic or neurological problems that may affect the tests,\n* Being willing to participate in the study.\n\nExclusion criteria for the COPD group:\n\n* Being in an acute exacerbation period,\n* Having any cardiovascular disease, orthopedic or neurological problems that may affect the tests,\n* Not being willing to participate in the study.\n\nInclusion criteria for the control group:\n\n* Being willing to participate in the study and being over 40 years old\n* Not having any known disease\n\nExclusion criteria for the control group:\n\n* Not being able to cooperate with the tests to be performed\n* Not being willing to participate in the study","40 Years",{"count":63,"type":23},144,"OBSERVATIONAL","Health literacy is important for controlling disease progression and living a healthy life with illness. High health literacy is associated with higher cognitive performance and lower health-related quality of life. Physical, psychological, and social impairments are seen in chronic obstructive pulmonary disease (COPD). Studies investigating the relationship between health literacy and functional capacity, quality of life, physical activity, cognitive function, health-related behavior, and activities of daily living in individuals with COPD are limited. Therefore, the aim of this study was to compare individuals with COPD with healthy individuals in terms of health literacy, functional capacity, quality of life, physical activity, cognitive function, health-related behavior, and activities of daily living and to investigate the relationship between health literacy and functional capacity, quality of life, physical activity, cognitive function, health-related behavior, and activities of daily living in individuals with COPD.",[67,29,68],"COPD","Health-Related Behavior","RECRUITING","2026-06-24",{"date":72,"type":46},"2026-06-25",{"date":74,"type":46},"2024-06-15",{"date":76,"type":23},"2027-06-15",{"name":78,"class":53},"Hacettepe University",1,{"id":81,"slug":82,"hasResults":12,"nctId":83,"briefTitle":84,"officialTitle":85,"acronym":4,"eligibilityCriteria":86,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":87,"targetDuration":4,"studyType":64,"phases":4,"briefSummary":89,"conditions":90,"keywords":94,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":97,"lastUpdatePostDateStruct":98,"startDateStruct":99,"completionDateStruct":101,"leadSponsor":103,"locationsCount":4},"100644131","burden-of-care-and-health-literacy-of-caregivers-in-the-emergency-department-100644131","NCT07666373","Burden of Care and Health Literacy of Caregivers in the Emergency Department","The Relationship Between Caregiver Burden and Health Literacy Among Caregivers of Patients With Chronic Diseases Presenting to the Emergency Department","The patient having visited the Yalova Training and Research Hospital Emergency Department.\n\nBeing at least 18 years of age. Being cognitively capable of answering the data collection tools (scales\u002Fquestionnaires).\n\nVolunteering to participate in the study and providing informed consent.\n\nExclusion Criteria:\n\nRefusal to participate in the research voluntarily. Not being the primary caregiver for the patient. Inability to communicate or complete the scales due to cognitive or language barriers.\n\n\\-",{"count":88,"type":23},350,"This study aims to investigate the relationship between caregiver burden and health literacy among primary caregivers of patients with chronic diseases presenting to the emergency department. The study will be conducted in the Emergency Department of Yalova Training and Research Hospital and will include at least 300 caregivers. Data will be collected using a sociodemographic questionnaire, the Turkish Health Literacy Scale-32 (THLS-32), and the Zarit Burden Interview (ZBI). The findings are expected to contribute to a better understanding of caregivers' needs and to clarify the role of health literacy in caregiver burden among those providing care for individuals with chronic illnesses.",[91,29,92,93],"Caregiver Burden","Chronic Disease","Emergency Service Utilization",[91,29,95,96],"Family Caregivers","Emergency Service","2026-06-18",{"date":70,"type":46},{"date":100,"type":23},"2026-07-01",{"date":102,"type":23},"2027-05-31",{"name":104,"class":53},"University of Yalova",{"id":106,"slug":107,"hasResults":12,"nctId":108,"briefTitle":109,"officialTitle":110,"acronym":111,"eligibilityCriteria":112,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":113,"targetDuration":4,"studyType":24,"phases":115,"briefSummary":116,"conditions":117,"keywords":130,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":97,"lastUpdatePostDateStruct":133,"startDateStruct":135,"completionDateStruct":137,"leadSponsor":139,"locationsCount":79},"100638424","ecardiacrehab---a-hybrid-patient-centered-ehealth-programme-100638424","NCT07590635","eCardiacRehab - a Hybrid Patient-Centered eHealth Programme","eCardiacRehab - a Randomized Controlled Trial on a Hybrid Home-Based Patient-Centered eHealth Programme With Tailored Solutions","eCardiacRehab","Inclusion Criteria:\n\n* Adult Norwegian (or Scandinavian) speaking patients (≥ 18 years) who have a Norwegian national identification number\n* With coronary artery disease after percutaneous coronary intervention\n* Living at home\n* Have internet available\n* Provide signed informed consent\n\nExclusion Criteria:\n\n* Patients with cognitive impairment that may interfere with the ability to comply with the study protocol\n* Severe aortic stenosis\n* Severe arrhythmias\n* Expected lifetime less than one year as determined by study personnel\n* Otherwise clinically unstable\n* Not fully revascularized\n* Awaits percutaneous coronary intervention or coronary artery bypass graft surgery\n* Inability to comply with the study protocol due to any physical disability, somatic disease, or mental problems as determined by study personnel",{"count":114,"type":23},1000,[26],"The overall aim of eCardiacRehab trial is to meet rehabilitation needs of patients with coronary artery disease (CAD) regardless of their access to traditional place-based rehabilitation by developing and evaluating the efficacy and cost effectiveness of an interdisciplinary and comprehensive home-based hybrid programme. eCardiacRehab address patient- and system level challenges to increase access to cardiac rehabilitation (CR). We give particular attention to older patients, women, and those with comorbidities or mental health challenges. The vision of the hybrid home-based eCardiacRehab programme is to make CR available to all.\n\neCardiacRehab is a prospective, multicentre randomized open-label blinded end point evaluation (PROBE) trial. The primary endpoint is a hierarchical composite endpoint using a win-ratio framework combining cardiovascular (CV) death, unplanned contacts to the Emergency Department (ED) for observation or admission (\\>24 hours) for CV disease, and quality of life. Inclusion criteria are adult Scandinavian speaking patients (≥ 18 years) who have a Norwegian national identification number, with CAD treated with Percutaneous Coronary Intervention (PCI), are living at home, and have internet available to them and providing signed informed consent. Exclusion criteria are patients with severe aortic stenosis, severe arrhythmias, expected lifetime less than one year as determined by study personnel, otherwise clinically unstable, not fully revascularized, awaits PCI or coronary artery bypass graft operation (CABG) or inability to comply with the study protocol due to any physical disability, somatic disease, cognitive impairment or mental health challenges as determined by study personnel.",[118,119,120,121,122,123,124,29,125,126,127,128,129],"Comorbidities and Coexisting Conditions","Ethics","Continuity of Patient Care","Older Adults (65 Years and Older)","Cost-Benefit Analysis","Adherence, Medication","Secondary Prevention of Coronary Heart Disease","eHealth Literacy","Mental Health","Cardiac Rehabilitation","Womens's Health","Coronary Artery Disease (CAD)",[127,131,132],"Coronary Artery Disease","Percutaneous Coronary Intervention",{"date":134,"type":46},"2026-06-23",{"date":136,"type":46},"2026-05-21",{"date":138,"type":23},"2037-12-31",{"name":140,"class":53},"Haukeland University Hospital",{"id":142,"slug":143,"hasResults":12,"nctId":144,"briefTitle":145,"officialTitle":146,"acronym":147,"eligibilityCriteria":148,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":149,"targetDuration":4,"studyType":64,"phases":4,"briefSummary":151,"conditions":152,"keywords":156,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":167,"lastUpdatePostDateStruct":168,"startDateStruct":170,"completionDateStruct":172,"leadSponsor":174,"locationsCount":176},"100641416","patient-ai-trust-dynamics-before-and-after-orthopedic-consultation-ortho-op-gpt-100641416","NCT07631585","Patient AI Trust Dynamics Before and After Orthopedic Consultation (ORTHO-OP-GPT)","Longitudinal Pre-Post Patient AI Trust Dynamics in Orthopedic Outpatients: A Mixed-Methods Observational Study With Matched Physician-Patient Dyads","ORTHO-OP-GPT","Inclusion Criteria:\n\n* Age 18 years or older\n* Presenting to an orthopedic outpatient clinic for any consultation\n* Able to read and respond to a Turkish-language questionnaire\n* Provides informed consent\n\nExclusion Criteria:\n\n* Inability to complete a self-report questionnaire (e.g., severe cognitive impairment, language barrier)\n* Re-presentation within the same recruitment window (each patient is enrolled only once)\n* Refusal of consent for either T0 or T1",{"count":150,"type":23},180,"Patients increasingly consult artificial intelligence (AI) chatbots such as ChatGPT for health information before clinical visits, yet the impact of an actual orthopedic consultation on patient trust in AI-derived information remains unknown. This prospective longitudinal observational study quantifies how a single orthopedic outpatient consultation modifies patient trust in AI chatbots, the concordance between AI-derived and physician-delivered information, and patient anxiety, using a paired pre-post survey design supplemented by a matched physician-side assessment. Adult patients (18 years and older) presenting to two orthopedic outpatient clinics in Cyprus complete a brief pre-consultation questionnaire (T0) capturing demographics, AI use patterns, prior AI consultation regarding the current complaint, baseline trust, expectations, and anxiety. Immediately after their consultation they complete a second questionnaire (T1) assessing concordance with physician advice, trust change, consultation facilitation, post-consultation anxiety, and future intention. The consulting physician completes a brief 30-second post-visit form capturing whether AI was discussed, the medical accuracy of AI-derived information conveyed by the patient, and the effect of the AI discussion on consultation duration. The primary outcomes are the paired within-patient change in AI trust between T0 and T1 and physician-patient concordance on AI versus physician advice. Target enrollment is 180 to obtain 150 paired completed assessments.",[153,154,29,155],"Patient Health Information Seeking Behavior","Trust","Orthopedics",[157,158,159,160,161,162,163,164,165,166],"ChatGPT","large language model","artificial intelligence chatbot","patient education","health information seeking","trust","physician-patient communication","orthopedics","cross-sectional","pre-post","2026-06-14",{"date":169,"type":46},"2026-06-17",{"date":171,"type":23},"2026-06",{"date":173,"type":23},"2027-01",{"name":175,"class":53},"Utku Gürhan",2,{"id":178,"slug":179,"hasResults":12,"nctId":180,"briefTitle":181,"officialTitle":182,"acronym":4,"eligibilityCriteria":183,"healthyVolunteers":12,"sex":184,"minAge":19,"maxAge":20,"enrollmentInfo":185,"targetDuration":4,"studyType":24,"phases":187,"briefSummary":188,"conditions":189,"keywords":4,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":196,"lastUpdatePostDateStruct":197,"startDateStruct":199,"completionDateStruct":201,"leadSponsor":203,"locationsCount":79},"100553095","patient-clinical-linkages-to-improve-trust-and-engagement-in-postpartum-healthcare-100553095","NCT06481631","Patient-clinical Linkages to Improve Trust and Engagement in Postpartum Healthcare","Empowering Women for Postpartum Care and Reproductive Health in Mississippi Delta","Inclusion Criteria:\n\n* Identified as high risk pregnancy\n* Postpartum mothers\u002Fparents 18-45 years\n* Resident of the one of 5 target counties (Washington, Bolivar, Scott, Humphreys, and Carroll)\n* Maternal healthcare providers in target counties\n* Maternal community health leaders\n\nExclusion Criteria:\n\n* not identified as high risk pregnancy\n* 18 years of age postpartum\n* cesarean birth\n* non-resident of the 5 target counties","FEMALE",{"count":186,"type":23},250,[26],"Maternal mortality in the United States is higher than in peer nations and has not decreased since 1990. Beyond mortality, severe maternal mortality impacts far too many women. Not only are these high rates alarming, but notable racial\u002Fethnic and socioeconomic disparities exist. These inequities are highly regional, with women living in the rural southeast part of the United States, including the Mississippi Delta, having the highest rates of maternal mortality and morbidity. Unfortunately, these disparities have proven to be stubbornly resistant to interventions, necessitating an innovative multifaceted approach focused on community practice, building trust, and prioritizing patient voices. To meet this need, this proposal aims to establish the Mississippi Delta Research Center of Excellence for Maternal Health with the goal of addressing preventable maternal mortality, decreasing severe maternal morbidity, and promoting maternal health equity in partnership with the Mississippi Delta community. This patient-clinical linkages intervention study will evaluate the effectiveness of a multilevel and multisector communication and health literacy strategy to increase trust and engagement in postpartum healthcare among women in the Mississippi Delta, with a specific focus on Black women, their families, and their communities.\n\nThese research projects both have the overarching goal of partnering with the community to determine and meet the needs of pregnant and postpartum women in the Mississippi Delta and address the disparities within maternity health and health care outcomes.",[190,191,192,29,193,194,195],"Family Dynamics","Trust in Healthcare System","Family Structure","Contraception","Maternal Behavior","Postpartum Mood Disturbance","2026-06-04",{"date":198,"type":46},"2026-06-08",{"date":200,"type":46},"2025-06-01",{"date":202,"type":23},"2030-06-30",{"name":204,"class":53},"Jackson State University",{"id":206,"slug":207,"hasResults":12,"nctId":208,"briefTitle":209,"officialTitle":210,"acronym":211,"eligibilityCriteria":212,"healthyVolunteers":12,"sex":18,"minAge":213,"maxAge":214,"enrollmentInfo":215,"targetDuration":4,"studyType":24,"phases":217,"briefSummary":218,"conditions":219,"keywords":222,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":229,"lastUpdatePostDateStruct":230,"startDateStruct":231,"completionDateStruct":233,"leadSponsor":235,"locationsCount":79},"100638389","effectiveness-of-health-literacy-program-for-polypharmacy-patients-hlp-ckd-100638389","NCT07622134","Effectiveness of Health Literacy Program for Polypharmacy Patients (HLP-CKD)","Effectiveness of the Health Literacy Promotion Program to Prevent Chronic Kidney Disease of Patients Who Use Polypharmacy","HLP-CKD","Inclusion Criteria:\n\n* Patients aged 55-74 years diagnosed with non-communicable diseases.\n* Currently taking 5 or more medications daily (Polypharmacy) for at least 6 months.\n* Have at least one risk factor for chronic kidney disease (e.g., Hypertension or Diabetes).\n* Able to communicate, read, and write in Thai.\n* Willing to participate in the 8-week program and follow-up assessments.\n\nExclusion Criteria:\n\n* Patients already diagnosed with Chronic Kidney Disease (CKD) stage 3 - 5.\n* Having severe cognitive impairment or psychiatric disorders that prevent participation.\n* Having severe complications or being in an unstable clinical condition.\n* Planning to move out of the study area during the 12-week study period.","55 Years","74 Years",{"count":216,"type":23},104,[26],"This study aims to evaluate the effectiveness of a health literacy promotion program in preventing chronic kidney disease (CKD) among patients who use multiple medications (polypharmacy). Participants will be divided into two groups: an experimental group receiving the health literacy program and a control group receiving standard care. The study will measure improvements in health literacy levels and CKD prevention behaviors over a specific period. It is expected that the program will help patients better manage their medications and reduce the risk of developing kidney complications.",[220,221,29],"Chronic Kidney Diseases","Polypharmacy",[223,224,225,226,227,228],"Health Literacy Program","CKD Prevention","Medication Management","Nursing Intervention","Randomized Controlled Trial","Thailand","2026-06-03",{"date":196,"type":46},{"date":232,"type":23},"2026-06-15",{"date":234,"type":23},"2026-11-15",{"name":236,"class":53},"Nakhon Pathom Rajabhat University",{"id":238,"slug":239,"hasResults":12,"nctId":240,"briefTitle":241,"officialTitle":242,"acronym":4,"eligibilityCriteria":243,"healthyVolunteers":17,"sex":18,"minAge":244,"maxAge":245,"enrollmentInfo":246,"targetDuration":4,"studyType":24,"phases":248,"briefSummary":249,"conditions":250,"keywords":252,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":256,"lastUpdatePostDateStruct":257,"startDateStruct":259,"completionDateStruct":261,"leadSponsor":263,"locationsCount":79},"100637628","mest--a-school--based-health-literacy-intervention-trial-100637628","NCT07601815","MEST : A School- Based Health Literacy Intervention Trial","A Cluster- Randomized Controlled Trial Evaluating the MEST Work Strategy to Improve Health Literacy Among Upper Secondary School Students","Inclusion Criteria:\n\n* Students 16-24 years\n* Students enrolled in upper secondary school classes\n* Provided informed consent\n\nExclusion Criteria:\n\n\\- Students \\\u003C16 years and \\> 24 years","16 Years","24 Years",{"count":247,"type":23},1800,[26],"The purpose of this study is to evaluate the effectiveness of the MEST work strategy in upper secondary schools. MEST is a school based, health promoting intervention delivered by school health services and designed to strengthen students' health literacy and mental well being. The study assesses whether implementation of the MEST work strategy results in improved health literacy and mental well being compared with usual school health services.\n\nThis study is a cluster randomized superiority trial in which upper secondary schools are assigned either to an intervention group implementing the MEST work strategy or to a control group continuing with school health services as usual. Student reported outcomes are collected using digitally administered questionnaires during school hours at baseline, prior to initiation of the intervention, and at 4 and 9 months following intervention initiation (end of the school year).",[29,251],"Adolescent Health",[253,254,255],"Health Promotion","School Health Services","Upper Secondary School","2026-05-18",{"date":258,"type":46},"2026-05-22",{"date":260,"type":23},"2026-08-17",{"date":262,"type":23},"2027-09-30",{"name":264,"class":265},"Norwegian Institute of Public Health","OTHER_GOV",{"id":267,"slug":268,"hasResults":12,"nctId":269,"briefTitle":270,"officialTitle":271,"acronym":4,"eligibilityCriteria":272,"healthyVolunteers":12,"sex":18,"minAge":273,"maxAge":274,"enrollmentInfo":275,"targetDuration":4,"studyType":24,"phases":277,"briefSummary":278,"conditions":279,"keywords":284,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":295,"lastUpdatePostDateStruct":296,"startDateStruct":298,"completionDateStruct":299,"leadSponsor":300,"locationsCount":79},"100580843","health-care-transition-readiness-short-form-video-intervention-100580843","NCT06842576","Health Care Transition Readiness Short-Form Video Intervention","Transition Readiness Mobile Health Intervention: Co-Design and Pilot Study","Inclusion Criteria:\n\n* Patients in subspecialty clinics\n* Between 12 and 17 years old\n* With access to an internet-connected device\n* Speaking English or Spanish\n* With sufficient cognitive capacity to understand the study procedures, as assessed via a teach back method.\n\nExclusion Criteria:\n\n* none","12 Years","17 Years",{"count":276,"type":23},44,[26],"The goal of this clinical trial is to assess whether social-media style short-form health education videos can increase health care transition readiness, self-efficacy, emotional well-being, health literacy, and appointment attendance, compared with publicly available health education resources in adolescents with chronic illnesses. The main question it aims to answer is:\n\n-Hypothesize social media intervention will increase health care transition readiness, self-efficacy, emotional well-being, health literacy, and appointment attendance compared to publicly available health education website immediately post intervention and at 6 month follow up.\n\nParticipants will be randomly assigned to one of the interventions and access the intervention for 20 minutes and complete 30-60 minutes of surveys.",[280,29,281,282,283],"Health Care Transition Readiness","Self Efficacy","Emotional Wellbeing","Appointment Attendance",[285,286,287,288,289,290,291,292,293,294],"mobile health","health education","transition readiness","chronic illness","adolescence","health literacy","social media","video","self efficacy","emotional wellbeing","2026-05-08",{"date":297,"type":46},"2026-05-12",{"date":200,"type":46},{"date":43,"type":23},{"name":301,"class":53},"Children's Hospital Los Angeles",{"id":303,"slug":304,"hasResults":12,"nctId":305,"briefTitle":306,"officialTitle":307,"acronym":308,"eligibilityCriteria":309,"healthyVolunteers":17,"sex":18,"minAge":310,"maxAge":4,"enrollmentInfo":311,"targetDuration":4,"studyType":24,"phases":313,"briefSummary":314,"conditions":315,"keywords":318,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":324,"lastUpdatePostDateStruct":325,"startDateStruct":326,"completionDateStruct":328,"leadSponsor":330,"locationsCount":79},"100636473","social-cognitive-theory-based-education-for-improving-health-outcomes-in-older-adults-100636473","NCT07566143","Social Cognitive Theory-Based Education for Improving Health Outcomes in Older Adults","Effect of a Social Cognitive Theory-Based Education Program on Self-Efficacy, Healthy Lifestyle Behaviors, and Health Literacy in Older Adults Attending Primary Care Centers: A Randomized Controlled Trial","SCT-OLD","Inclusion Criteria:\n\n* Aged 65 years and older\n* Able to communicate in Turkish\n* Willing to participate and provide informed consent\n* Having sufficient cognitive ability to follow the education program\n\nExclusion Criteria:\n\n* Severe cognitive impairment\n* Severe psychiatric disorder\n* Acute or life-threatening medical condition","65 Years",{"count":312,"type":23},100,[26],"This study aims to evaluate the effectiveness of a Social Cognitive Theory-based education program on self-efficacy, healthy lifestyle behaviors, and health literacy in older adults aged 65 years and over attending primary care centers. Participants will be assigned to either an intervention group receiving a structured education program or a control group receiving routine care. The intervention consists of three face-to-face educational sessions delivered weekly. Outcomes will be assessed at baseline and 4-6 weeks after the intervention using validated scales. The findings are expected to contribute to improving health behaviors and health literacy among older adults in primary care settings.",[316,29,281,317],"Health Behavior","Aging",[319,320,321,322,323,227],"Social Cognitive Theory","Health Education","Older Adults","Primary Care","Healthy Lifestyle","2026-05-04",{"date":295,"type":46},{"date":327,"type":23},"2026-05",{"date":329,"type":23},"2026-07",{"name":331,"class":53},"Muhammet Faruk Yigit",{"id":333,"slug":334,"hasResults":12,"nctId":335,"briefTitle":336,"officialTitle":337,"acronym":4,"eligibilityCriteria":338,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":339,"targetDuration":4,"studyType":24,"phases":341,"briefSummary":342,"conditions":343,"keywords":347,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":349,"lastUpdatePostDateStruct":350,"startDateStruct":352,"completionDateStruct":354,"leadSponsor":356,"locationsCount":79},"100631825","comparing-original-patient-educational-materials-vs-ai-simplified-materials-to-improve-patient-comprehension-and-health-literacy-100631825","NCT07505719","Comparing Original Patient Educational Materials vs. AI-Simplified Materials to Improve Patient Comprehension and Health Literacy","AI-Simplified Patient Educational Materials: Investigating the Potential for Improved Patient Comprehension and Health Literacy","Inclusion Criteria:\n\n* Parents or guardians of pediatric patients receiving treatment at Hospital for Special Surgery\n\nExclusion Criteria:\n\n* Non-English Speaking\n* primary occupation is in healthcare\n* participants with prior knowledge on the condition pertaining to the material (osteogenesis imperfecta)",{"count":340,"type":23},80,[26],"Poor health literacy and patient comprehension have been associated with adverse health outcomes. Patient educational materials (PEMs) are articles that are intended to assist patients in their understanding of a given medical condition. Given that the average American adult reads at the 8th grade level, the American Medical Association and the Center for Disease Control recommend PEM be written at the 6th grade level. However, literature has found the majority of PEMs to be written significantly higher than the 8th grade level. In order to improve their readability, a number of studies have displayed the effectiveness of large language models (LLMs) such as ChatGPT to simplify the text of a given PEM. Despite the improvement in readability, the effectiveness of these simplified PEMs on improving patient comprehension of the AI augmented material has yet to be investigated.\n\nThe purpose of our study is to test whether the improvement in readability found in AI-simplified PEMs corresponds to a greater understanding of the material compared to the original PEM. Understanding if AI-simplified PEM truly improves comprehension could further support this use case for AI and aid providers and healthcare organizations in improving the health literacy of their patients.\n\nThis study aims to answer the following question:\n\nDo AI simplified PEMs improve the comprehension of pediatric orthopaedic conditions?\n\nResearchers will compare AI-simplified PEMs to their original, unmodified counterparts in order to see if there is any difference in post reading comprehension of the participants.\n\nParticipation in the study will include:\n\n* A brief baseline survey (e.g. demographics and educational attainment)\n* A randomly assigned reading of either the original PEM or the AI simplified version.\n* A 10 question post-reading multiple choice quiz",[344,29,345,346],"Artificial Intelligence (AI)","Patient Comprehension","Patient Educational Material",[348,29,345,346],"Artificial Intelligence","2026-04-02",{"date":351,"type":46},"2026-04-03",{"date":353,"type":46},"2026-02-13",{"date":355,"type":23},"2027-05",{"name":357,"class":53},"Hospital for Special Surgery, New York",{"id":359,"slug":360,"hasResults":12,"nctId":361,"briefTitle":362,"officialTitle":363,"acronym":4,"eligibilityCriteria":364,"healthyVolunteers":17,"sex":184,"minAge":365,"maxAge":366,"enrollmentInfo":367,"targetDuration":4,"studyType":24,"phases":369,"briefSummary":370,"conditions":371,"keywords":374,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":377,"lastUpdatePostDateStruct":378,"startDateStruct":380,"completionDateStruct":382,"leadSponsor":384,"locationsCount":79},"100631609","the-effect-of-womens-heart-health-awareness-program-100631609","NCT07502911","The Effect of Women's Heart Health Awareness Program","The Effect of a Heart Health Awareness Program on Women's Knowledge, Attitudes, and Practice Toward Cardiovascular Disease and Health Literacy: A Single-Blind Cluster Randomized Controlled Trial","Inclusion Criteria:\n\n* Being female,\n* Aged between 20 and 64 years (inclusive),\n* Being literate,\n* Regularly attending any course at the Family Center,\n* Active user of the WhatsApp application.\n\nExclusion Criteria:\n\n* Being an immigrant with a Turkish language barrier (unable to communicate in Turkish),\n* Being pregnant,\n* Being in the postpartum period,\n* Having a prior diagnosis of any cardiovascular disease,\n* Having a prior diagnosis of any type of cancer.","20 Years","64 Years",{"count":368,"type":23},207,[26],"The aim of this study is to examine the effect of a gender-specific heart health protection awareness program, incorporating video-supported reminder messages, on knowledge, attitudes, practices (KAP) regarding cardiovascular diseases and health literacy among adult women aged 20 to 64 with no prior diagnosis of cardiovascular disease. The centers where the study is conducted will be divided into intervention (n=4) and control (n=5) groups using cluster randomization. While the intervention group receives a heart health awareness program consisting of three sessions in total, including education, risk factor screening, and individual counseling over a period of three weeks, the control group will receive standard of care. Data will be collected at the beginning of the first session and after the completion of the final session.",[372,373,29],"Cardiovascular Health","Cardiovascular Risk Factors",[375,376,290],"Cardiovascular diseases","women's health","2026-03-25",{"date":379,"type":46},"2026-03-31",{"date":381,"type":23},"2026-04-06",{"date":383,"type":23},"2026-04-20",{"name":385,"class":265},"Lokman Hekim University",{"id":387,"slug":388,"hasResults":12,"nctId":389,"briefTitle":390,"officialTitle":390,"acronym":391,"eligibilityCriteria":392,"healthyVolunteers":17,"sex":18,"minAge":61,"maxAge":4,"enrollmentInfo":393,"targetDuration":395,"studyType":64,"phases":4,"briefSummary":396,"conditions":397,"keywords":399,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":406,"lastUpdatePostDateStruct":407,"startDateStruct":409,"completionDateStruct":411,"leadSponsor":413,"locationsCount":79},"100626580","cancer-literacy-education-and-awareness-resources-for-prostate-care-100626580","NCT07437482","Cancer Literacy Education and Awareness Resources for Prostate Care","CLEAR-PC","Inclusion Criteria:\n\n* Adults aged 40 years or older\n* Member of the general population, patient, caregiver, or healthcare professional eligible for the study component\n* Able to understand and communicate in the language used at the study site\n* Able to provide informed consent\n* Willing to participate in surveys, interviews, workshops, or intervention activities as applicable\n* Access to digital or non-digital materials required for the intervention, depending on study arm\n\nExclusion Criteria:\n\n* Participation in another study that could interfere with the outcomes of this study",{"count":394,"type":23},3100,"3 Years","The CLEAR-PC project addresses the critical issue of low health literacy in prostate cancer prevention and care, recognising that inadequate health literacy leads to difficulties in understanding complex medical information, limits shared decision making, and increases health inequalities. Given the high prevalence and complexity of prostate cancer, the project aims to design and development of a comprehensive strategy to improve health literacy in the Prostate cancer prevention and care, considering individual capacities, the role of healthcare professionals and organisations, and the influence of social and cultural contexts. In the design and development of this new strategy, the investigators apply both action research and cocreation methodologies because by involving all stakeholders (general population, vulnerable population patients, health professionals, policy makers and other target groups), we ensure that the resulting strategy is user-centred, implementable and responsive to their needs. The design and development of the new strategy will follow a systematic cycle: (a) problem diagnosis by assessing individual contexts, healthcare professionals, organisational aspects and the social framework; (b) adaptation of existing health literacy tools to the specific context of prostate cancer prevention and care, integrating them into a new strategy, followed by evaluation of their usability and acceptability; and (c) observation of results in practice and reflection. Co-creation will be a critical component throughout this process, ensuring that stakeholders are actively involved at every stage, from diagnosis of challenges to refinement and validation of solutions. The consortium, composed of institutions from Spain, Portugal, Croatia, Belgium, the Netherlands and Cyprus, leverages multidisciplinary expertise to create digital and non-innovative tools and educational resources to address public health disparities, reduce misinformation and support decision-making on prostate cancer prevention and care.",[29,398],"Prostate Cancer",[400,401,402,403,404,405],"Prostate cancer","Health literacy","Diagnosis","Screening","Treatment","Palliative care","2026-02-28",{"date":408,"type":46},"2026-03-03",{"date":410,"type":23},"2026-03",{"date":412,"type":23},"2028-09",{"name":414,"class":53},"Universidad Miguel Hernandez de Elche",{"id":416,"slug":417,"hasResults":12,"nctId":418,"briefTitle":419,"officialTitle":420,"acronym":4,"eligibilityCriteria":421,"healthyVolunteers":17,"sex":18,"minAge":4,"maxAge":422,"enrollmentInfo":423,"targetDuration":4,"studyType":24,"phases":424,"briefSummary":425,"conditions":426,"keywords":432,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":441,"lastUpdatePostDateStruct":442,"startDateStruct":444,"completionDateStruct":446,"leadSponsor":448,"locationsCount":79},"100563342","addressing-food-insecurity-plant-based-food-prescription-program-100563342","NCT06614920","Addressing Food Insecurity: Plant-Based Food Prescription Program","Addressing Food-Insecurity: Plant-Based Food Prescription Program to Improve Health Food Access","Inclusion Criteria:\n\n* Participants will be all ages 0-99 (all arms)\n* Families living under the federal poverty line AND who have food insecurity (all arms except Arm 2 which can include families with income above the federal poverty line who do not have food insecurity).\n* Families cared for in either the Pediatric Mobile Clinic, Pediatric, Family Medicine, Internal Medicine or Med-Peds primary care clinics in the UHealth\u002FJackson Health System\u002FDade County Street Response.\n\nExclusion Criteria:\n\n* Families who are not under the federal poverty line AND are not food insecure (all arms except Arm 2, which will include participants of all socioeconomic statuses and regardless of food security status, with no exclusion criteria in this category).\n* Families who are not actively receiving outpatient primary care (all arms).","99 Years",{"count":312,"type":23},[26],"Reduce food insecurity by improving plant-based health food consumption, access, health and nutrition literacy and the health of the food-insecure families we serve.",[29,427,428,429,430,431],"Nutrition, Healthy","Nutrition Poor","Food Insecurity","Food Insecurity Among Children","Low Income Population",[433,434,435,436,437,438,439,440],"Plant-based food prescription program","Plant-based","Food prescription","Food insecurity","Poverty","Nutrition education","Plant-based nutrition literacy","Plant-based nutrition education","2026-02-01",{"date":443,"type":46},"2026-02-04",{"date":445,"type":46},"2025-01-09",{"date":447,"type":23},"2028-03",{"name":449,"class":53},"University of Miami",{"id":451,"slug":452,"hasResults":12,"nctId":453,"briefTitle":454,"officialTitle":454,"acronym":455,"eligibilityCriteria":456,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":457,"targetDuration":4,"studyType":64,"phases":4,"briefSummary":459,"conditions":460,"keywords":4,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":462,"lastUpdatePostDateStruct":463,"startDateStruct":465,"completionDateStruct":467,"leadSponsor":469,"locationsCount":4},"100622089","determinants-of-primary-care-health-professionals-numeracy-skills-and-practices-and-association-with-patient-health-literacy-and-quality-of-care-100622089","NCT07379086","Determinants of Primary Care Health Professionals' Numeracy Skills and Practices and Association With Patient Health Literacy and Quality of Care","Num-Pro-Qual","Inclusion criteria:\n\n* Patients over 18 years of age\n* having declared one of the participating general practitioners as their treating physician\n* declaring to be regularly followed by one of the participating physicians (at least 2 consultations in the last 12 months) for whom a non-opposition collection was carried out\n\nExclusion criteria:\n\n* diagnosis of major cognitive impairment\n* lack of mastery of the French language or lack of ability to understand oral or written instructions\n* patient under legal protection regime",{"count":458,"type":23},500,"To enable appropriate risk representation for patients, health care professionals (HCPs) must have a personal understanding of quantitative data. To date, a limited number of studies on physicians' numeracy skills and practices show that, although physicians perform better than the general population, not all physicians have mastered basic numeracy skills. Low numeracy among physicians was associated with lower quality adherence to good practice recommendations, inaccurate inferences about test results and side effect risks, and reluctance to share numerical information with patients. The primary objective will be to explore the determinants of the objective numeracy level of primary care professionals. A cross-sectional survey will be conducted on a sample of primary care professionals practicing in the west of Occitanie (former Midi-Pyrenées region). Objective numeracy will be measured using the Adaptive Berlin Numeracy Test (ABNT) and the Abbreviated Numeracy Scale, whereas subjective numeracy will be assessed using the Subjective Numeracy Scale (SNS-3). The Health Literacy Questionnaire (HLQ) will be used for patients.",[29,461],"Numeracy","2026-01-23",{"date":464,"type":46},"2026-01-30",{"date":466,"type":23},"2026-06-01",{"date":468,"type":23},"2027-11-15",{"name":470,"class":53},"MSPU de Pins-Justaret",{"id":472,"slug":473,"hasResults":12,"nctId":474,"briefTitle":475,"officialTitle":476,"acronym":477,"eligibilityCriteria":478,"healthyVolunteers":17,"sex":18,"minAge":479,"maxAge":4,"enrollmentInfo":480,"targetDuration":4,"studyType":24,"phases":482,"briefSummary":483,"conditions":484,"keywords":489,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":493,"lastUpdatePostDateStruct":494,"startDateStruct":496,"completionDateStruct":498,"leadSponsor":500,"locationsCount":4},"100621023","open-space-and-closed-years-100621023","NCT07365228","Open Space and Closed Years","OPEN SPACE AND CLOSED YEARS","OS&CY","Inclusion Criteria:\n\n* physical fitness status which allows active participation in the physical exercising program organized as a tretment\n\nExclusion Criteria:\n\n* health conditions not allowing the participation in treatment program","50 Years",{"count":481,"type":23},150,[26],"The primary objective of this project is to examine the effects of a specific multicomponent physical activity program (MPAP), conducted in an outdoor setting, on the health and functional-motor status (HFMS) of women over the age of 60. Additionally, the study will investigate the influence of sociodemographic factors (SDF), physical literacy (PL), and health literacy (HL) on the baseline HFMS and the subsequent changes resulting from the KTP.\n\nStudy Methodology\n\nThe program participants will consist of older women (\\>60 years; n=60) whose current HFMS allows for participation in the exercise protocol. They will be divided into two groups:\n\nExperimental Group: Will participate in the MPAP.\n\nControl Group: Will not participate in the MPAP.\n\nThe exercise intervention (MPAP) will include a combination of aerobic activities, strength exercises, balance, and flexibility. It will be conducted two to three times per week across two three-month cycles, separated by a three-month break.\n\nData Collection and Environment Assessments: Sociodemographic factors, physical literacy, and health literacy will be measured at the start of the study. A series of HFMS indicators will be recorded before and after each exercise cycle.\n\nSetting: The MPAP will be performed outdoors in a public park.\n\nProject Significance Beyond analyzing the direct effects of the exercise program and the correlations between the measured variables, this project will contribute to a deeper understanding of the importance of the natural environment in implementing goal-oriented physical activity for the elderly population.",[485,29,486,487,488],"Physical Fitness","Lipid Profile","Body Composition","Physical Literacy",[490,491,492],"physical fitness","health status","postmenopausal women","2026-01-15",{"date":495,"type":46},"2026-01-26",{"date":497,"type":23},"2026-01-01",{"date":499,"type":23},"2029-06-01",{"name":501,"class":53},"Goran Kuvacic",{"id":503,"slug":504,"hasResults":12,"nctId":505,"briefTitle":506,"officialTitle":507,"acronym":4,"eligibilityCriteria":508,"healthyVolunteers":17,"sex":184,"minAge":19,"maxAge":310,"enrollmentInfo":509,"targetDuration":4,"studyType":24,"phases":511,"briefSummary":512,"conditions":513,"keywords":515,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":519,"lastUpdatePostDateStruct":520,"startDateStruct":522,"completionDateStruct":524,"leadSponsor":526,"locationsCount":79},"100617550","evaluation-of-the-effectiveness-of-health-literacy-education-given-to-women-by-teach-back-method-100617550","NCT07320079","Evaluation of the Effectiveness of Health Literacy Education Given to Women by Teach-Back Method","Evaluation of the Effectiveness of Health Literacy Education Given to Women by Teach-Back Method: Randomized Controlled Trial","Inclusion Criteria:\n\n* Women aged between 18 and 65 years\n* Those with a General Health Questionnaire-12 score below 4\n\nExclusion Criteria:\n\n* Illiterate women\n* Male individuals\n* Those with communication difficulties\n* Healthcare professionals (physicians, midwives, nurses, etc.)\n* Emergency patients",{"count":510,"type":23},74,[26],"This study aims to enhance women's health literacy levels and to examine the effectiveness of the teach-back teaching technique in improving women's health literacy. The research was designed as a randomized controlled study. In addition, this study aims to answer the question of whether health literacy education delivered using the teach-back method is effective in improving women's health literacy levels. Within the scope of the study, participants in the experimental group will receive health literacy education using the teach-back technique, while the control group will receive standard care. Data will be collected using a questionnaire method.",[29,514],"Teach Back",[401,516,517,518],"Teach-back","Women","Self-efficacy","2026-01-12",{"date":521,"type":46},"2026-01-14",{"date":523,"type":23},"2026-04",{"date":525,"type":23},"2027-07",{"name":527,"class":53},"Istanbul University - Cerrahpasa",{"id":529,"slug":530,"hasResults":12,"nctId":531,"briefTitle":532,"officialTitle":533,"acronym":534,"eligibilityCriteria":535,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":536,"enrollmentInfo":537,"targetDuration":4,"studyType":24,"phases":539,"briefSummary":540,"conditions":541,"keywords":552,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":556,"lastUpdatePostDateStruct":557,"startDateStruct":559,"completionDateStruct":561,"leadSponsor":563,"locationsCount":79},"100531998","the-fit-with-us-study-100531998","NCT06207084","The Fit With Us Study","Precision-based Teleexercise Trial to Increase Adherence in People With Disabilities","FITWITHUS","Eligible participants must meet the following criteria to be included: (1) live with a permanent physical disability that limits their mobility; (2) be 18 to 89 years of age; (3) have broadband internet access; (4) be able to speak and read English; and (5) be able to attend coaching and training sessions during the weekdays.\n\nParticipants are excluded from participation if they (1) possess significant visual acuity that prevents seeing a computer screen to follow a home exercise program; (2) have been regularly engaging in exercise for the previous 3 months; (3) are unable to use their arms and their legs at all to exercise; (4) are unsafe to exercise; (5) self-report that they are currently pregnant","89 Years",{"count":538,"type":23},257,[26],"The purpose of this 32-week study is to use an innovative experimental design known as SMART (Sequential Multiple Assignment Randomized Trial), which will allow us to determine the best way to sequence the delivery of teleexercise (referred to as an adaptive intervention), combined with predictive analytics on participant adherence in a stepped program of physical activity interventions. All 257 participants will have access to a library of recorded video exercise content, and a weekly wellness article. Some participants will receive health coaching calls (1st randomization). Analytic data will be used to determine which participants are responding or not responding to the intervention. Participants not responding after 4 weeks will receive either live one-on-one or group exercise training (2nd randomization). After 8 weeks, the participant will receive only pre-recorded exercise content and articles for a 24-week maintenance phase (weeks 9-32). The study outcomes are: The effectiveness of the adaptive interventions; Exploring mediating and moderating variables; Sensitivity analysis of the predictive analytics.",[542,543,544,545,546,547,548,29,281,549,550,551],"Mobility Limitations","Disability Physical","Telehealth","Health Coaching","Physical Activity","Behavior, Health","eHealth","Fatigue","Usability","Predictive Model",[553,554,555],"telehealth","health coaching","disability","2026-01-07",{"date":558,"type":46},"2026-01-09",{"date":560,"type":46},"2024-09-01",{"date":562,"type":23},"2029-02-01",{"name":564,"class":53},"University of Alabama at Birmingham",{"id":566,"slug":567,"hasResults":12,"nctId":568,"briefTitle":569,"officialTitle":570,"acronym":4,"eligibilityCriteria":571,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":572,"enrollmentInfo":573,"targetDuration":4,"studyType":24,"phases":575,"briefSummary":576,"conditions":577,"keywords":4,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":580,"lastUpdatePostDateStruct":581,"startDateStruct":583,"completionDateStruct":585,"leadSponsor":587,"locationsCount":4},"100608984","the-impact-of-medical-tv-drama-in-improving-literacy-on-neurocysticercosis-100608984","NCT07208656","The Impact of Medical TV Drama in Improving Literacy on Neurocysticercosis","The Impact of Medical TV Drama in Improving Literacy on Neurocysticercosis: An Online Open-Label Two-Arm Randomized Controlled Trial","Inclusion Criteria:\n\n* Aged 18 to 35 years\n* Proficient in English (reading and comprehension)\n* Has access to a stable internet connection\n* Possesses a screen-enabled device (e.g., smartphone, tablet, or computer)\n* Has access to the Netflix streaming platform\n\nExclusion Criteria:\n\n* Has formal education in medical or health sciences\n* Has a prior diagnosis of neurocysticercosis (NCC)\n* Has previously participated in any NCC-related health literacy or awareness program\n* Lacks access to the Netflix movie platform\n* Below 18 years or above 35 years of age","35 Years",{"count":574,"type":23},60,[26],"This randomized controlled trial evaluates whether exposure to a medical television drama improves knowledge of neurocysticercosis (NCC) among young adults. Sixty participants aged 18-35 will be randomly assigned to either an intervention group, which will watch a medically relevant TV episode (House M.D., Season 1, Episode 1), or a control group with no media exposure. Both groups will complete pre- and post-test questionnaires assessing knowledge of NCC. The primary outcome is change in NCC-related knowledge. Secondary outcomes include motivation to seek further health information and perceived credibility of the media source",[578,29,579],"Neurocysticercosis","Epilepsy","2025-11-26",{"date":582,"type":46},"2025-12-04",{"date":584,"type":23},"2025-12-15",{"date":586,"type":23},"2026-04-15",{"name":588,"class":589},"Cephas Health Research Initiative Inc, Ibadan, Nigeria","NETWORK",{"id":591,"slug":592,"hasResults":12,"nctId":593,"briefTitle":594,"officialTitle":594,"acronym":595,"eligibilityCriteria":596,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":597,"targetDuration":4,"studyType":24,"phases":599,"briefSummary":600,"conditions":601,"keywords":611,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":622,"lastUpdatePostDateStruct":623,"startDateStruct":625,"completionDateStruct":627,"leadSponsor":629,"locationsCount":176},"100611237","cocreating-action-to-improve-rationality-in-the-health-system-100611237","NCT07237971","Cocreating Action to Improve Rationality in the Health System","CAIR","Survey general population:\n\nA representative population survey of adult (aged 18 years and over) who are residents in the Municipal District 2 of Elche (Spain).\n\nSurvey community pharmacies:\n\nIndividuals who visit the pharmacies collaborating in the Municipal District 2 of Elche (Spain) to obtain any of the medications, aged 18 years and over for three a priori established medication groups.\n\n* Group 1 (Antidepressants and Anxiolytics): N05B, N05C, N06A.\n* Group 2 (Cardiovascular disease risk factor medication): A10B (antidiabetics), C10A (cholesterol-lowering drugs), C07A, C09A, C03C, C08C (antihypertensives).\n* Group 3 (Antibiotics): J01\n\nHealth service data from primary care:\n\nA series of aggregate indicators will be collected from the electronic information systems of the regional health authorities (Conselleria de Sanidad de la Generalitat Valenciana), which hosts information on both prescriptions made by physicians and those dispensed in the community pharmacies of the Valencian Community. These indicators will be calculated for individuals aged 18 years and over for groups 2 and 3, and 12 years and over for group 1 using aggregate data from health system's registries and, therefore, not considering 12 years old as minimum age limit of the eligible participants in the present study protocol registry. Furthermore, aggregate data about the number of consultations will be collected in the two primary care facilities in the study area for individuals aged 18 and over.\n\nQualitative methods and cocreation procedure:\n\nFocus groups, sociograms and in-depth interviews will include 6-8 participants and last approximately 90 minutes. Participation in the co-creation process will be open, voluntary, and will depend on the interest of individuals and entities in the area. Eligibility criteria:\n\n* People aged 18 and over who are residents or have a job or family connection in the Municipal District 2 of Elche (Spain) who are interested in participating, wish to be actively involved in the co-creation, planning, and implementation of community initiatives, and are available to attend the conferences, meetings, and workshops.\n* Representatives from community institutions and associations, including professionals from the Elche Public Health Center, primary care teams in the area, Elche Council staff, as well as professionals and volunteers from NGOs and other local organizations with experience in community work in the district.",{"count":598,"type":23},4000,[26],"Despite widespread recognition of social, economic, or environmental health determinants, health action remains heavily dominated by individual-level solutions (e.g., medication, patient counselling, vaccination). This study aims to stimulate changes in health system functioning by demonstrating how the cocreation of actions to address psychological well-being, cardiovascular health, and antimicrobial resistance from within the community can alleviate the burden on primary care services, reduce medicalisation and increase health equity.\n\nThe scientific approach uses mixed methods and incorporates theory from multiple disciplines. This study will appraise how the current system addresses psychological well-being, cardiovascular (CV) health, and rational use of antibiotics using a population survey, a survey of patients collecting their medication at community pharmacies, aggregate health service indicators on medication consumption and primary care consultations, and qualitative methods exploring stakeholders' perceptions.The investigators will undertake community-based participatory research to engage citizen scientists in the cocreation of community-led actions to promote psychological well-being, CV health, and prevent antimicrobial resistance. The design, implementation, and evaluation of the actions will apply an assets-based approach and apply theories and frameworks from implementation science in an iterative manner over 3 years. Finally, the impact of the cocreated actions will be analysed, considering effectiveness and broader contextual issues such as initiative adoption, implementation, and maintenance. The investigators will use a before-after comparison of survey indicators, an interrupted time-series analysis of health service data and qualitative analysis.\n\nThe goal is to demonstrate how the integration of community action with attention to the social determinants of health, can lead to a more rational approach to health care and ultimately improve health and health equity.",[602,603,29,604,605,606,607,608,609,610],"Health-Related Quality-of-Life","Social Capital","Community Based Participatory Research","Antibiotic Prescription","Mental Health Literacy","Cardio Vascular Disease","Antimicrobial Drug Resistance","Well-being","Health Equity",[612,613,614,401,615,616,617,618,619,620,621],"Community health","Cocreation action","Health system","Social capital","Community capital","Antibiotic drug use","Cardiovascular drug use","Psychotropic drug use","Health-related quality of life","Health equity","2025-11-24",{"date":624,"type":46},"2025-12-02",{"date":626,"type":46},"2025-10-21",{"date":628,"type":23},"2029-04-01",{"name":414,"class":53},{"id":631,"slug":632,"hasResults":12,"nctId":633,"briefTitle":634,"officialTitle":635,"acronym":636,"eligibilityCriteria":637,"healthyVolunteers":12,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":638,"targetDuration":4,"studyType":24,"phases":640,"briefSummary":641,"conditions":642,"keywords":647,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":649,"lastUpdatePostDateStruct":650,"startDateStruct":652,"completionDateStruct":654,"leadSponsor":656,"locationsCount":658},"100590724","nurse-led-telehealth-for-gout-100590724","NCT06971146","Nurse-Led Telehealth for Gout","Health Literacy-Based, Nurse-Led Telehealth Support for Gout Self-Management: the Danish Randomized GOUTCONNECT Trial","GoutConnect","Inclusion Criteria:\n\n* ≥18 years old\n* Fulfills ACR\u002FEULAR 2015 Gout Classification Criteria\n* Estimated Glomerular Filtration Rate (e-GFR) \\>30 ml\u002Fmin\n* Prescribed Allopurinol or Adenuric, and achieved two consecutive serum urate levels of two consecutive serum urate levels of ≤0.30 mmol\u002Fl for patients with tophi and ≤0.36 mmol\u002FL for patients without tophi\n* Have sufficient Danish reading and writing skills to understand information and complete questionnaires.\n\nExclusion Criteria:\n\n• Cognitively impaired, unable to understand or provide informed consent.",{"count":639,"type":23},200,[26],"The aim of this clinical trial is to evaluate whether nurse-led telehealth support helps individuals with gout better manage their condition and adhere to urate-lowering medication after discharge from a rheumatology clinic.\n\nEligible patients will be recruited from five rheumatology departments in the Central Denmark Region after achieving two consecutive target serum urate levels-below 0.36 mmol\u002FL, or below 0.30 mmol\u002FL for patients with tophi.\n\nParticipants will be adults with gout who meet specific medical criteria, are taking medications such as allopurinol or Adenuric, and are able to read and write Danish.\n\nParticipants will be randomly assigned to one of two groups:\n\n* Intervention group: nurse-led telehealth support.\n* Control group: usual care with follow-up by their general practitioner.\n\nThe primary goal is to support patients in maintaining healthy uric acid levels after 52 weeks.\n\nParticipants in the nurse-led group have the option to choose from four support options:\n\nI1: App-Based Support - an app provides information and reminders. I2: Letter Reminders - messages are sent via digital or postal mail. I3: Text Reminders - SMS messages are sent every three months. I4: Phone Support - nurses call three times a year to check in.",[29,643,644,544,645,646],"Gout Arthritis","Gout Initiating Urate-loweringUrate-lowering Therapy","Digital Health","Adherence",[648],"self-managment","2025-09-17",{"date":651,"type":46},"2025-09-18",{"date":653,"type":23},"2025-10-01",{"date":655,"type":23},"2027-08-01",{"name":657,"class":53},"University of Aarhus",5,{"id":660,"slug":661,"hasResults":12,"nctId":662,"briefTitle":663,"officialTitle":664,"acronym":4,"eligibilityCriteria":665,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":666,"enrollmentInfo":667,"targetDuration":4,"studyType":24,"phases":669,"briefSummary":670,"conditions":671,"keywords":675,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":681,"lastUpdatePostDateStruct":682,"startDateStruct":684,"completionDateStruct":686,"leadSponsor":688,"locationsCount":176},"100605057","from-health-information-to-health-decisions-integrating-mindfulness-into-digital-learning-and-daily-life-100605057","NCT07157566","From Health Information to Health Decisions Integrating Mindfulness Into Digital Learning and Daily Life","Effects of Mindfulness Practice and E-health Information Push on E-health Literacy, Media Literacy, Food Literacy, and Mindfulness Skills Among University Students in Macau","Inclusion Criteria:\n\nMindfulness Group\n\n1. Currently enrolled in a Physical Education (PE) class.\n2. Aged between 18 and 25 years.\n3. Willing to participate in the 8-week intervention and provide informed consent.\n4. Generally healthy and able to engage in physical activity.\n5. Proficient in Chinese.\n\nE-health Group\n\n1. Currently enrolled in a Physical Education (PE) class.\n2. Aged between 18 and 25 years.\n3. Willing to participate in the 8-week intervention and provide informed consent.\n4. Generally healthy and able to engage in physical activity.\n5. Proficient in Chinese.\n\nMindfulness + E-health Group\n\n1. Currently enrolled in a Physical Education (PE) class.\n2. Aged between 18 and 25 years.\n3. Willing to participate in the 8-week intervention and provide informed consent.\n4. Generally healthy and able to engage in physical activity.\n5. Proficient in Chinese.\n\nControl Group\n\n1. Currently enrolled in a Physical Education (PE) class.\n2. Aged between 18 and 25 years.\n3. Willing to participate in the 8-week intervention and provide informed consent.\n4. Generally healthy and able to engage in physical activity.\n5. Proficient in Chinese.\n\nExclusion Criteria:\n\nMindfulness Group\n\n1. Currently studying in medical, nutrition, or health-related fields.\n2. Pregnant or lactating.\n3. Severe mental health conditions or cognitive impairments affecting participation.\n4. Currently participating in other mindfulness or digital health programs.\n5. Involved in competitive sports (e.g., varsity athletes).\n6. Recent major life events (e.g., trauma or major illness) within the last 6 months.\n7. Unable to participate in PE classes due to medical or personal reasons.\n\nE-health Group\n\n1. Currently studying in medical, nutrition, or health-related fields.\n2. Pregnant or lactating.\n3. Severe mental health conditions or cognitive impairments affecting participation.\n4. Currently participating in other mindfulness or digital health programs.\n5. Involved in competitive sports (e.g., varsity athletes).\n6. Recent major life events (e.g., trauma or major illness) within the last 6 months.\n7. Unable to participate in PE classes due to medical or personal reasons.\n\nMindfulness + E-health Group\n\n1. Currently studying in medical, nutrition, or health-related fields.\n2. Pregnant or lactating.\n3. Severe mental health conditions or cognitive impairments affecting participation.\n4. Currently participating in other mindfulness or digital health programs.\n5. Involved in competitive sports (e.g., varsity athletes).\n6. Recent major life events (e.g., trauma or major illness) within the last 6 months.\n7. Unable to participate in PE classes due to medical or personal reasons.\n\nControl Group\n\n1. Currently studying in medical, nutrition, or health-related fields.\n2. Pregnant or lactating.\n3. Severe mental health conditions or cognitive impairments affecting participation.\n4. Currently participating in other mindfulness or digital health programs.\n5. Involved in competitive sports (e.g., varsity athletes).\n6. Recent major life events (e.g., trauma or major illness) within the last 6 months.\n7. Unable to participate in PE classes due to medical or personal reasons.","25 Years",{"count":668,"type":23},268,[26],"This research project aims to explore how combining e-health literacy with mindfulness practices can help university students navigate the complex landscape of e-health information and make more informed, healthier choices. Specifically, the study will assess the current levels of e-health literacy, food literacy, and media literacy among university students, and examine how these factors are related to critical thinking, decision-making confidence, and overall well-being. The project will involve a 4-arm design, including: (1) a mindfulness group, (2) an e-health group, (3) a mindfulness + e-health Group, and (4) a Control Group. Participants in the intervention groups will engage in short mindfulness exercises focused on mindful eating and movement during break times and cool-down sessions of their Physical Education (PE) classes. Additionally, digital health content (e.g., videos and articles) will be provided to enhance e-health literacy. This could lead to better-informed, more confident students who are able to make healthier choices in their daily lives, both during their university years and into the future.\n\nStudy Aim\n\nTo evaluate the effectiveness of an 8-week intervention delivered during PE classes, comparing the effects of:\n\n1\\. Mindfulness Group 2. E-health Group 3. Mindfulness + E-health Group 4. Control Group The intervention will assess changes in students' e-health literacy, food literacy, media literacy, critical thinking, self-compassion and decision-making self-efficacy over time, with assessments at pre-test, post-test, and 4-week follow-up.\n\nStudy Hypotheses:\n\n1. Students in the mindfulness group, e-health group, and combined group will show significantly greater improvements in all outcome measures from pre-test to post-test compared to the control group.\n2. The combined group will demonstrate the greatest gains in literacy and cognitive outcomes, due to the additive effect of both interventions.\n3. Improvements will be maintained at the 4-week follow-up, particularly in the combined group.",[29,672,673,674],"Food Literacy","Media Literacy","E-health Literacy",[227,401,676,672,677,678,679,680],"Media literacy","Mindfulness","Critical thinking","Decision making","e-health literacy","2025-09-09",{"date":683,"type":46},"2025-09-16",{"date":685,"type":23},"2025-09-20",{"date":687,"type":23},"2027-07-31",{"name":689,"class":53},"University of Macau",{"id":691,"slug":692,"hasResults":12,"nctId":693,"briefTitle":694,"officialTitle":695,"acronym":696,"eligibilityCriteria":697,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":422,"enrollmentInfo":698,"targetDuration":699,"studyType":64,"phases":4,"briefSummary":700,"conditions":701,"keywords":4,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":705,"lastUpdatePostDateStruct":706,"startDateStruct":708,"completionDateStruct":710,"leadSponsor":712,"locationsCount":79},"100605975","health-literacy-and-self-efficacy-expectations-in-patients-with-alcohol-related-liver-cirrhosis-100605975","NCT07169526","Health Literacy and Self-efficacy Expectations in Patients With Alcohol-related Liver Cirrhosis","Gesundheitskompetenz Und Selbstwirksamkeitserwartung Bei PatientInnen Mit Alkoholbedingter Leberzirrhose","GESA","Inclusion Criteria:\n\n* age (18-99)\n* liver cirrhosis\n\nExclusion Criteria:\n\n* pregnancy\n* insufficient german",{"count":639,"type":23},"1 Month","The goal of this observational study is to quantify the health literacy and self-efficacy in people with alcohol-related liver cirrhosis.",[702,29,703,704],"Self-Efficacy","Liver Cirrhosis","ALD - Alcoholic Liver Disease","2025-09-05",{"date":707,"type":46},"2025-09-11",{"date":709,"type":46},"2025-08-11",{"date":711,"type":23},"2026-10",{"name":713,"class":53},"Hannover Medical School",{"id":715,"slug":716,"hasResults":12,"nctId":717,"briefTitle":718,"officialTitle":718,"acronym":4,"eligibilityCriteria":719,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":720,"targetDuration":4,"studyType":24,"phases":721,"briefSummary":722,"conditions":723,"keywords":726,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":729,"lastUpdatePostDateStruct":730,"startDateStruct":732,"completionDateStruct":734,"leadSponsor":736,"locationsCount":4},"100605201","multimodal-radiology-report-to-improve-patient-centered-radiology-100605201","NCT07159438","Multimodal Radiology Report to Improve Patient-centered Radiology","Inclusion Criteria:\n\n* Age 18+ adults who have taken a radiology examination.\n\nExclusion Criteria:\n\n* N\u002FA",{"count":639,"type":23},[26],"The goal of this study is to learn if AI-generated video explanations help people better understand their radiology reports. The main question it aims to answer is:\n\nDo AI-generated videos help participants understand their medical imaging results better than written reports alone? Participants will send their own radiology images and written reports to the research team; receive a personalized AI-generated video that explains their results in easy-to-understand language; watch their video explanation (about 1-5 minutes long); and complete 15-minute online survey about how well the video helped them understand their results.",[29,724,725,348],"Diagnostic Imaging","Imaging Results",[727,728,348],"Patient-centered Understanding","Radiology Reports","2025-08-28",{"date":731,"type":46},"2025-09-08",{"date":733,"type":23},"2026-12",{"date":735,"type":23},"2028-12",{"name":737,"class":53},"Harvard Medical School (HMS and HSDM)",{"id":739,"slug":740,"hasResults":12,"nctId":741,"briefTitle":742,"officialTitle":743,"acronym":4,"eligibilityCriteria":744,"healthyVolunteers":12,"sex":18,"minAge":395,"maxAge":274,"enrollmentInfo":745,"targetDuration":4,"studyType":64,"phases":4,"briefSummary":746,"conditions":747,"keywords":4,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":749,"lastUpdatePostDateStruct":750,"startDateStruct":752,"completionDateStruct":754,"leadSponsor":756,"locationsCount":79},"100603589","health-literacy-in-the-perioperative-setting-100603589","NCT07138482","Health Literacy in the Perioperative Setting","Health Literacy and Social Determinants of Health (SDOH) in the Perioperative Setting","Inclusion Criteria:\n\n* Caregivers of children age 3-17 years\n* Patient undergoing ambulatory dental rehabilitation, orchiopexy, inguinal hernia repair, or tonsillectomy +\u002F- adenoidectomy +\u002F- ear tubes under general anesthesia.\n* Primary language must be English, Spanish, Arabic, Nepali, or Somali.\n\nExclusion Criteria:\n\n* ASA ≥ 3\n* chronic pain condition\n* inpatient\n* regional anesthesia.",{"count":639,"type":23},"The purpose of this study is to determine the association of the social determinants of health with perioperative health literacy in caregivers of children presenting for surgery. Another purpose is to determine the association of caregiver health literacy with preoperative caregiver anxiety and postoperative patient pain scores.",[748,29],"Pediatric Surgery","2025-08-21",{"date":751,"type":46},"2025-08-22",{"date":753,"type":46},"2025-06-04",{"date":755,"type":23},"2028-06",{"name":757,"class":53},"Brittany Willer"]