[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"healthy-nutrition\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:healthy-nutrition":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,46,80,107,140],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":31,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100456084","health-related-benefits-of-introducing-table-olives-into-the-diet-of-young-adults-olives-for-health-100456084",false,"NCT05218980","Health-related Benefits of Introducing Table Olives Into the Diet of Young Adults: Olives For Health","Inclusion Criteria:\n\n* Yale College Freshman, Sophomore, or Junior\n* Ability and desire to sign informed consent\n* Stated willingness to comply with all study procedures and availability for the duration of the study\n* Male or female, age 18 on the day of consent\n* Ability and desire to consume 6 olives daily\n\nExclusion Criteria:\n\n* Yale College Senior\n* Unable to provide informed consent form\n* Self-reported pregnancy\n* Unwillingness to comply with all study procedures and\u002For be available for the duration of the study\n* Inability and desire to consistently consume 6 olives per day\n* Inability to consume fruit with pits\n* Current and consistent use of \\> 6 olives per day\n* Current and consistent use of ≥ 1 tablespoon of extra virgin olive oil (EVOO) per day\n* Known allergic reactions to olives and\u002For their derivatives\n* Known reactions to blood draw",true,"ALL","18 Years","23 Years",{"count":20,"type":21},226,"ESTIMATED","INTERVENTIONAL",[24],"NA","The purpose of this study is to assess whether introducing table olives into the diet results in health-related benefits for young adults. Several studies have shown that addition of olives as part of somebody's diet has a positive impact on cardiovascular, metabolic, and inflammatory factors. However, there have not been many studies among young, healthy adults. This study will compare levels of specific biomarkers, collected through blood draw, at the beginning of the study and after 5 weeks, to evaluate the effects of investigational daily olive consumption.",[27,28,29,30],"Healthy Diet","Cholesterol","Healthy Lifestyle","Healthy Nutrition",[32],"olives","NOT_YET_RECRUITING","2026-05-11",{"date":36,"type":37},"2026-05-13","ACTUAL",{"date":39,"type":21},"2027-01",{"date":41,"type":21},"2027-06",{"name":43,"class":44},"Yale University","OTHER",1,{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":52,"eligibilityCriteria":53,"healthyVolunteers":15,"sex":16,"minAge":54,"maxAge":55,"enrollmentInfo":56,"targetDuration":4,"studyType":58,"phases":4,"briefSummary":59,"conditions":60,"keywords":61,"overallStatus":70,"whyStopped":4,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":45},"100506082","baylor-infant-and-toddler-biomarker-of-nutrition-study-100506082","NCT05869760","Baylor Infant and Toddler Biomarker of Nutrition Study","Observational Validation of Skin Carotenoid Biomarker of Infant and Toddler Carotenoid Intake","BITBONS","Inclusion Criteria:\n\n* healthy\n* born at term (more than or equal to 37 weeks gestation)\n* between the 1st to 99th weight for age percentile at 3 months of age\n* participating guardian speaks, reads, and understands English\n* guardian categorizes child as non-Hispanic white, Hispanic white, Asian, or non-Hispanic Black\n\nExclusion Criteria:\n\n* physician-diagnosed metabolic, absorptive, or endocrine condition\n* diagnosed food intolerance or allergy\n* has a sibling enrolled in the study","3 Months","24 Months",{"count":57,"type":21},208,"OBSERVATIONAL","Young children rely on their foods and drinks for the nutrients they need to grow, like energy, protein, vitamins, and minerals. In addition to nutrients, there are substances in fruits, vegetables, milk and formula, called phytochemicals, that can support health. While researchers know more about the role of phytochemicals in adult health, researchers know surprisingly little about how phytochemicals can support health in young children. One group of phytochemicals are called the carotenoids. Carotenoids are responsible for the red, orange, and yellow colors in some fruits and vegetables. In adults, carotenoids can support visual function. Researchers also know that measuring levels of carotenoids in the blood or optically in the skin, can serve as an indirect measurement of what child and adults eat.\n\nThe purpose of this study is to determine how a child's usual intake of carotenoids is related to their visual development and their blood and skin levels of carotenoids. The study involves 6 visits. For each visit, we will ask about the child's recent diet, will measure their body size, collect a blood sample, collect optical measurements of their skin, and will test how sharp their vision is.",[30,27],[62,63,64,65,66,67,68,69],"infant","toddler","carotenoids","biomarkers","food intake","visual development","contrast sensitivity","skin carotenoids","RECRUITING","2026-03-24",{"date":73,"type":37},"2026-03-27",{"date":75,"type":37},"2023-06-26",{"date":77,"type":21},"2028-11-30",{"name":79,"class":44},"Baylor College of Medicine",{"id":81,"slug":82,"hasResults":11,"nctId":83,"briefTitle":84,"officialTitle":85,"acronym":86,"eligibilityCriteria":87,"healthyVolunteers":15,"sex":16,"minAge":17,"maxAge":88,"enrollmentInfo":89,"targetDuration":4,"studyType":22,"phases":91,"briefSummary":92,"conditions":93,"keywords":94,"overallStatus":70,"whyStopped":4,"lastUpdateSubmitDate":98,"lastUpdatePostDateStruct":99,"startDateStruct":101,"completionDateStruct":103,"leadSponsor":105,"locationsCount":45},"100464792","sex-differences-in-metabolism-following-a-high-fat-meal-100464792","NCT05332301","Sex Differences in Metabolism Following a High-fat Meal","Exploring Sex Differences in the Acute Postprandial Metabolic Response to a High-fat Mixed Macronutrient Meal Challenge in Healthy Young Humans","HFM","Inclusion Criteria:\n\n* BMI between 18.5 and 30.0 kg\u002Fm2\n* Weight stable for the past 6 months (± 2kg)\n* Exercise at or below the Canadian Physical Activity Guidelinesa\n* Fasting blood glucose \\\u003C6.0 mM\n* Resting blood pressure \\\u003C140\u002F90 mmHg\n* No hormone-altering contraceptive use (e.g., pill, patch, ring, injection)\n\nExclusion Criteria:\n\n* Smoking\n* Diabetes, cancer, or other metabolic disorders\n* Cardiac or gastrointestinal problems\n* Infectious disease\n* Barium swallow or nuclear medicine scan in the previous 3 weeks\n* Pregnant or breastfeeding\n* Diagnosis of polycystic ovary syndrome\n* Follow a vegan or vegetarian diet\n* Not fully vaccinated against COVID19","35 Years",{"count":90,"type":21},24,[24],"Long-term consumption (i.e., several weeks to months) of a diet that is high in fat (\\>35% daily calories from fat) is associated with the development of insulin resistance, a condition that can lead to a diagnosis of type 2 diabetes. Women tend to be better protected against the development of high-fat diet-induced insulin resistance compared with men, but it is not fully understand why this sex difference exists. It is possible that women metabolize high-fat meals differently than men, which might explain why they are less likely to develop type 2 diabetes over the course of their lifetime. However, no one has ever compared the metabolic response to a high-fat meal between men and women in the hours immediately after ingestion.\n\nDuring this study, the investigators will administer a single high-fat \"fast-food\" style breakfast meal (846 kcal, of which 58% is fat) to 24 health young adults (n=12 men, n=12 women) 18-35 years old. Their objective is to determine whether there are differences in the way men and women metabolize high-fat meals, such as this one. The research team will take regular blood samples after participants ingest this meal to measure features of glucose metabolism (e.g., blood glucose and insulin) as well as resting oxygen uptake (VO2) measurements to examine how much of this meal is burned for energy in the hours immediately after ingestion.",[30],[95,96,97],"glucose metabolism","lipid metabolism","substrate oxidation","2025-08-14",{"date":100,"type":37},"2025-08-19",{"date":102,"type":37},"2022-10-04",{"date":104,"type":21},"2027-05-30",{"name":106,"class":44},"Kirsten Bell",{"id":108,"slug":109,"hasResults":11,"nctId":110,"briefTitle":111,"officialTitle":111,"acronym":112,"eligibilityCriteria":113,"healthyVolunteers":15,"sex":16,"minAge":114,"maxAge":115,"enrollmentInfo":116,"targetDuration":4,"studyType":22,"phases":118,"briefSummary":119,"conditions":120,"keywords":124,"overallStatus":70,"whyStopped":4,"lastUpdateSubmitDate":130,"lastUpdatePostDateStruct":131,"startDateStruct":133,"completionDateStruct":135,"leadSponsor":137,"locationsCount":139},"100502140","wakaya-rising-up-for-choctaw-youth-health-100502140","NCT05818384","Wakaya: Rising Up for Choctaw Youth Health","Wakaya","Inclusion Criteria:\n\n* Be enrolled in Choctaw Nation of Oklahoma (CNO)\n* Live within CNO tribal region for 12 months\n\nYES to one of the following:\n\n* Consumed sweetened beverages or processed\u002Ffast food 2x or more per week; OR\n* Engaged in excessive sitting or lying around (\\>540 min\u002Fday) or engage in small screen recreation (\\>2 hours\u002Fday); OR\n* Physical activity - spend \\\u003C60 minutes\u002Fday outdoors or \\\u003C2.5 hrs per week in moderate or vigorous physical activity OR spend \\\u003C60 minutes a day in moderate or vigorous intensity aerobic activity; OR\n* Engage in any T.V., small screen\u002Fvideo game recreation (\\> 2 hours\u002Fday)\n\nExclusion Criteria:\n\n* opioid\u002Fmethamphetamine drug use (2 times or more in past month)\n* allergic reactions to food (e.g. peanuts), plant (poison oak or ivy) or insects (e.g. bees, fire ants) that caused difficulty in breathing or necessitated hospitalization or caused an anaphylactic reaction\n* disability that prevents student from walking or from engaging in exercise\n* aggressive, violent, combative or inappropriate behaviors\n* inability to follow directions\n* psychotic symptoms","12 Years","19 Years",{"count":117,"type":21},176,[24],"Investigators will conduct a two-group randomized waitlist-control trial to assess the efficacy of the Wakaya: Rising Up for Choctaw Youth Health program on improving physical activity, reducing sedentary behaviors and improving healthful eating habits as well as delaying or reducing alcohol, tobacco and other drug use. Wakaya is an experiential, outdoor, nature-based program grounded in Choctaw values. It is a multi-level intervention that increases individual motivation and leadership skills to make healthy behavioral choices for behavior and exercise.",[121,30,122,123],"Obesity, Adolescent","Sedentary Behavior","Drug Abuse",[125,126,127,128,129],"Native Americans","Youth","Oklahoma","Adolescents","Obesity prevention","2025-02-18",{"date":132,"type":37},"2025-02-20",{"date":134,"type":37},"2023-04-28",{"date":136,"type":21},"2027-04-30",{"name":138,"class":44},"University of Washington",2,{"id":141,"slug":142,"hasResults":11,"nctId":143,"briefTitle":144,"officialTitle":145,"acronym":146,"eligibilityCriteria":147,"healthyVolunteers":15,"sex":16,"minAge":148,"maxAge":149,"enrollmentInfo":150,"targetDuration":4,"studyType":22,"phases":152,"briefSummary":153,"conditions":154,"keywords":156,"overallStatus":70,"whyStopped":4,"lastUpdateSubmitDate":171,"lastUpdatePostDateStruct":172,"startDateStruct":174,"completionDateStruct":176,"leadSponsor":178,"locationsCount":139},"100550832","the-begin-study-bifidobacterium-infantis-to-newborns-effects-of-modulating-the-gut-microbial-composition-on-growth-immune-function-and-inflammatory-conditions---a-randomized-placebo-controlled-double-blinded-intervention-trial-100550832","NCT06452199","The BEGIN Study Bifidobacterium Infantis to Newborns: Effects of Modulating the Gut Microbial Composition on Growth, Immune Function and Inflammatory Conditions - a Randomized Placebo-controlled Double-blinded Intervention Trial","The BEGIN Study Bifidobacterium Infantis to Newborns: Effects of Modulating the Gut Microbial Composition on Growth, Immune Function and Inflammatory Conditions","BEGIN","Inclusion Criteria:\n\n* Infants born at term (above gestational week 37)\n* Infants born in Region Midtjylland Denmark receiving a Danish CPR number.\n* Parents age is above 18\n* At least one parent holds a smartphone (for study app) and is able to fill out Danish questionaries\n* Both legal parents are willing and able to provide written informed consent prior to participation, regarding both themselves and their future child.\n\nExclusion Criteria:\n\n* Multiple pregnancy\n* Child diagnosed with immune deficiency, renal, gastrointestinal, hepatic, or endocrine diseases\n* Parents expecting to give other probiotics","1 Day","7 Days",{"count":151,"type":21},1000,[24],"The goal of The BEGIN Study, a randomized controlled double-blinded intervention trial, is to learn if probiotics, with Bifidobacterium longum subspecies infantis Bifin02 (B. infantis), given to healthy newborns can affect various health outcomes and to explore impacts of the infant gastrointestinal microbiome. The main questions it aims to answer are:\n\n* Does B. infantis probiotics impact immune function and does it lower the number of bacterial infections and use of antibiotics?\n* Does B. infantis probiotics impact overall health, development, growth and wellbeing?\n* Does B. infantis probiotics impact inflammatory diseases, allergies and autoimmune diseases\n\nResearchers will compare B. infantis probiotics to a placebo (a look-alike substance that contains no probiotic) to see if B. infantis colonization impact the human immunesystem and various clinical and biochemical health markers.\n\nParticipants (parents) will\n\n* Orally administrate the B. infantis probiotic to their newborn child daily in three weeks from 7 days of age.\n* Answer baseline and follow up questionnaires in a study app\n* Take five stool samples from the child and one stool sample from the mother\n* Collect a 4 week of passive dust sample at home (Electrostatic Dust fall Collector)\n* Donate one dried bloodspot and one blood sample from their child",[155,30],"Healthy",[157,158,159,160,161,162,163,164,165,166,167,168,169,170],"Microbiota","Gastrointestinal Microbiome","Probiotics","Bifidobacterium longum subspecies infantis","Paediatrics","Infant","Child","Immunology","Infections","Inflammation","Growth and Development","Colic","Respiratory Tract Diseases","Metabolism","2024-09-30",{"date":173,"type":37},"2024-10-01",{"date":175,"type":37},"2024-06-10",{"date":177,"type":21},"2043-11",{"name":179,"class":44},"University of Aarhus"]