[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"healthy-subjects-or-volunteers\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:healthy-subjects-or-volunteers":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,50,79],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":23,"studyType":24,"phases":4,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":4},"100611086","training-and-testing-database-for-imu-based-gait-analysis-methods-100611086",false,"NCT07236008","Training and Testing Database for IMU Based Gait Analysis Methods","IMU-GAIT","Inclusion Criteria:\n\n* Healthy subjects with no motor impairments that disrupt the walking pattern.\n* No history of pain in the lower limbs in the past 6 months.\n* No history of lower limbs injuries\u002Fsurgeries in the past 6 months.\n* Language: Dutch and\u002For English and\u002For French speakers.\n* Age 18-65 years old\n* Subjects must be able to understand the instructions and to answer questions. Additionally, they should be able to; signal pain, fear, discomfort; give inform consent.\n\nExclusion Criteria:\n\n* Persons with comorbidity that could hinder the study (e.g.: unstable cardiovascular system disorders, lung disorders, severe osteoporosis).\n* Individuals with metal implants or skin conditions that would make sensor or marker placement difficult.",true,"ALL","18 Years","65 Years",{"count":21,"type":22},150,"ESTIMATED","1 Day","OBSERVATIONAL","The goal of this study is to establish a high-quality, synchronised dataset of gait events (GE) by simultaneously collecting inertial measurement unit (IMU) data and validated ground truth detections using a Vicon motion capture system. The primary objective is to address existing limitations in GE detection - such as poor generalisability, limited data diversity, and lack of precise synchronisation - through a rigorous protocol that ensures accuracy and transparency. The experiment is structured in three phases. First, Vicon-derived GE will be validated and refined using complementary modalities (force plates and video recordings). Next, deep learning (DL) algorithms will be developed and evaluated for GE detection directly from IMU data, with Vicon annotations serving as ground truth. Finally, the impact of differences in GE timing on spatiotemporal gait parameters (SGP) will be analysed to assess the feasibility of using IMU-only systems for reliable gait analysis.\n\nBy achieving these objectives, the study aims to improve the accuracy of GE detection from wearable sensors and enable more accessible, scalable, and reliable gait analysis outside the laboratory environment.",[27],"Healthy Subjects or Volunteers",[29,30,31,32,33,34,35,36,37],"Gait analysis","Gait events","Spatiotemporal gait parameters (SGP)","Inertial measurement units (IMU)","Wearable sensors","Motion capture (Vicon)","Deep learning","Machine learning","Healthy adults","NOT_YET_RECRUITING","2025-11-17",{"date":41,"type":42},"2025-11-19","ACTUAL",{"date":44,"type":22},"2025-12-01",{"date":46,"type":22},"2029-12-31",{"name":48,"class":49},"Vrije Universiteit Brussel","OTHER",{"id":51,"slug":52,"hasResults":11,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":56,"eligibilityCriteria":57,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":58,"targetDuration":4,"studyType":60,"phases":61,"briefSummary":63,"conditions":64,"keywords":65,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":77,"locationsCount":4},"100600494","hydrogen-rich-water-and-resting-metabolism-in-young-adults-100600494","NCT07098221","Hydrogen-Rich Water and Resting Metabolism in Young Adults","Effects of Hydrogen-Rich Water on Resting Metabolism in Healthy Young Adults: A Randomized, Double-Blind, Placebo-Controlled Crossover Trial","H2REST","Inclusion Criteria:\n\n* Aged 18-35 years\n* BMI between 18.5 and 25.0 kg\u002Fm²\n* Apparently healthy, with no history of chronic disease\n* Non-smoker, not currently using nicotine-containing products\n* Able to provide informed consent\n* Willing to refrain from alcohol, caffeine, and strenuous exercise for 24 hours before each study visit\n* Able to comply with study procedures, including fasting and attending all study visits\n\nExclusion Criteria:\n\n* Diagnosed metabolic, cardiovascular, respiratory, gastrointestinal, or endocrine disorders\n* Use of dietary supplements or medications affecting metabolism (within the past 2 weeks)\n* Allergy or intolerance to components of the hydrogen or placebo beverages\n* Pregnant or lactating\n* Shift work or irregular sleep schedule\n* Participation in another clinical study within the past 30 days",{"count":59,"type":22},24,"INTERVENTIONAL",[62],"NA","The H2REST trial is a randomized, double-blind, placebo-controlled crossover study investigating the acute effects of a single dose of hydrogen-rich water (HRW) on resting metabolism in healthy young adults. Participants complete two testing sessions-receiving either HRW or placebo in a randomized order-followed by standardized metabolic testing. Primary outcomes include resting energy expenditure, respiratory exchange ratio, and substrate utilization measured via indirect calorimetry. The study aims to assess whether acute HRW intake can modulate metabolic rate and fuel preference at rest, and to explore inter-individual variability in response.",[27],[66,67,68,69,70],"Hydrogen-rich water","Resting metabolism","Energy expenditure","Substrate utilization","Metabolic rate","2025-07-24",{"date":73,"type":42},"2025-08-01",{"date":75,"type":22},"2025-09-01",{"date":44,"type":22},{"name":78,"class":49},"University of Novi Sad",{"id":80,"slug":81,"hasResults":11,"nctId":82,"briefTitle":83,"officialTitle":83,"acronym":4,"eligibilityCriteria":84,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":85,"targetDuration":4,"studyType":60,"phases":87,"briefSummary":88,"conditions":89,"keywords":91,"overallStatus":94,"whyStopped":4,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":98,"completionDateStruct":100,"leadSponsor":102,"locationsCount":104},"100598630","investigating-the-impact-of-afferent-stimulation-on-proprioceptive-function-in-post-stroke-rehabilitation-100598630","NCT07073989","Investigating the Impact of Afferent Stimulation on Proprioceptive Function in Post-Stroke Rehabilitation","Inclusion Criteria:\n\n* For healthy subjects:\n\n  1. No neurological or orthopedic conditions affecting upper limb movement.\n  2. No surgical interventions on the upper limbs within the past 6 months.\n  3. General physical condition adequate to perform the session.\n  4. Cognitive abilities sufficient to understand and carry out the experimental procedure.\n* For stroke survivors:\n\n  1. Ischemic or hemorrhagic stroke resulting in motor impairments in the upper limb.\n  2. Chronic stroke condition.\n  3. Subjects with sufficient cognitive abilities to follow instructions and actively participate in the therapy.\n  4. Mini-Mental State Examination (MMSE) score \\> 24.\n  5. Subjects presenting hemiparesis and mild-to-moderate impairment in the upper limb (score on the Fugl-Meyer Motor Assessment for the upper limb, sections A-D, between 35 and 53 points). The maximum score on the FM scale is 66, with the following severity classifications:\n* 0-15: severe impairment\n* 16-34: moderate-to-severe impairment\n* 35-53: mild-to-moderate impairment\n* 54-66: mild impairment 6. Subjects presenting upper limb hypertonia with a score below 3 on the Modified Ashworth Scale.\n\n  7\\. Subjects who have signed the informed consent document to voluntarily participate in the experiments.\n\nExclusion Criteria:\n\n1. Acute musculoskeletal disorders.\n2. Peripheral vascular diseases.\n3. Acute cardiopulmonary conditions.\n4. Acute neurological disorders.\n5. Restricted mobility of upper limb joints due to any cause.\n6. Pain as a cause of impaired upper limb mobility.",{"count":86,"type":22},20,[62],"The objective of this study is to assess the functionality of a sensory stimulation device that uses mechanical vibrations and low-intensity electrical currents to deliver proprioceptive feedback to stroke patients regarding their movements.",[27,90],"Chronic Stroke",[92,93],"Afferent stimulation","Proprioception","RECRUITING","2025-07-09",{"date":97,"type":42},"2025-07-20",{"date":99,"type":42},"2025-06-17",{"date":101,"type":22},"2025-09",{"name":103,"class":49},"Julio S. Lora Millán",1]