[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"hearing-loss-bilateral-sensorineural\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:hearing-loss-bilateral-sensorineural":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,41,71,97,120],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":40},"100615017","a-pivotal-study-to-evaluate-the-clinical-benefit-performance-and-safety-of-a-totally-implantable-cochlear-implant-tici-system-in-adults-100615017",false,"NCT07287124","A Pivotal Study to Evaluate the Clinical Benefit, Performance and Safety of a Totally Implantable Cochlear Implant (TICI) System in Adults","A Pivotal, Pre-market, Prospective, Interventional, Multi-centre Study to Evaluate Clinical Benefit, Performance, and Safety of the TI1132 Implant in an Adult Population With Sensorineural Hearing Loss","ELEVATE","Inclusion Criteria:\n\n* Individuals aged 18 years and older at time of consent.\n* Clinically established sensorineural hearing loss (SNHL) defined by a four frequency (500, 1000, 2000, 4000 Hz) pure-tone average unaided threshold (PTA4) of ≥70 dB HL in the ear to be implanted.\n* Compromised functional hearing in the aided condition defined as ≤40% correct on a word recognition test in the ear to be implanted.\n* Clinically established SNHL defined by a four-frequency (500, 1000, 2000 \\& 4000 Hz) pure-tone average unaided threshold (PTA4) of ≥30 dB HL in the contralateral ear.\n* Candidate is a fluent speaker in the language used to assess speech perception performance as determined by the investigator.\n* Direct access to a compatible Smart Phone.\n* Willing and able to provide written informed consent.\n\nExclusion Criteria:\n\n* Prior cochlear implantation, in either ear, or medical plan for cochlear implantation during the clinical investigation, contralateral to the ear to be implanted.\n* Candidates with single-sided deafness as determined by the investigator.\n* Intra-axial (within-the-brain) lesions or deafness due to lesions of the acoustic nerve affecting the ear to be implanted.\n* Middle ear infection (including acute otitis media, chronic otitis media, suppurative otitis media, or serous drainage) in the ear to be implanted either at the time of surgery or within 3 months prior to enrolment.\n* Presence of a tympanic membrane perforation or a history of otologic surgery within 3 months prior to enrolment, in the ear to be implanted.\n* Previously reported diagnosis of auditory neuropathy, in the ear to be implanted.\n* Ossification, malformation or any other cochlear anomaly, such as common cavity, that might prevent complete insertion of the electrode array, in the ear to be implanted.\n* Current cerebrospinal fluid (CSF) shunts or drains, existing perilymph fistula, skull fracture or CSF leaks.\n* Severe, or poorer, bilateral sensorineural hearing loss prior to 5 years of age, as reported by the participant.\n* Severe, or poorer, sensorineural hearing loss for more than 20 years, as reported by the participant, in the ear to be implanted.\n* Medical or psychological conditions that contraindicate general anaesthesia, surgery, or participation in the clinical investigation as determined by the investigator.\n* Pre-existing skin condition that could jeopardize wound healing as judged by the investigator e.g., psoriasis, dermatitis, use of corticosteroids, uncontrolled diabetes.\n* Unrealistic expectations on the part of the participant, regarding the possible benefits, risks, and limitations inherent to the surgical procedure(s) and prosthetic devices, as determined by the Investigator.\n* Additional disabilities that may affect the participant's participation or safety during the clinical investigation.\n* Unable or unwilling to comply with all requirements of the clinical investigation, as determined by the investigator.\n* Pregnant or breastfeeding women.\n* Investigator site personnel directly affiliated with this study and\u002For their immediate families. Immediate family is defined as spouse, parent, child or sibling.\n* Cochlear employees or employees of Contract Research Organisations or contractors engaged by Cochlear for the purposes of the investigation.\n* Current participation, or participation in another interventional clinical study\u002Ftrial in the past 30 days, involving an investigational drug or device (unless Cochlear sponsored and determined by Investigator or Sponsor to not impact this investigation).","ALL","18 Years",{"count":20,"type":21},56,"ESTIMATED","INTERVENTIONAL",[24],"NA","This pivotal study examines the clinical efficacy and safety of an investigational totally implantable cochlear implant (TICI) system. The system includes a microphone placed under the skin to detect speech and sound from the environment, providing the option to hear without any visible external parts. This study will involve adults with sensorineural hearing loss, a type of hearing loss caused by damage to the inner ear or auditory nerve (the nerve that carries sound signals from the ear to the brain). Participants will complete hearing tests and questionnaires to evaluate how well the system works and how it affects their daily life.",[27],"Hearing Loss, Bilateral Sensorineural","RECRUITING","2026-06-18",{"date":31,"type":32},"2026-06-23","ACTUAL",{"date":34,"type":32},"2026-04-03",{"date":36,"type":21},"2028-08",{"name":38,"class":39},"Cochlear","INDUSTRY",11,{"id":42,"slug":43,"hasResults":11,"nctId":44,"briefTitle":45,"officialTitle":45,"acronym":4,"eligibilityCriteria":46,"healthyVolunteers":47,"sex":17,"minAge":48,"maxAge":4,"enrollmentInfo":49,"targetDuration":4,"studyType":51,"phases":4,"briefSummary":52,"conditions":53,"keywords":54,"overallStatus":59,"whyStopped":4,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":61,"startDateStruct":63,"completionDateStruct":65,"leadSponsor":67,"locationsCount":70},"100641353","cochlear-implantation-and-social-outcomes-100641353","NCT07584837","Cochlear Implantation and Social Outcomes","Inclusion Criteria:\n\n* Age \\>= 60 years\n* English or Spanish speaking\n* older adults with bilateral moderate to profound sensorineural hearing loss who are candidates for cochlear implants or have undergone cochlear implantation.\n\nExclusion Criteria:\n\n* Age \\\u003C60 years\n* Unable to complete questionnaires in English or Spanish",true,"60 Years",{"count":50,"type":21},40,"OBSERVATIONAL","The goal of this clinical trial is to learn if hearing devices, like cochlear implants, affect social and cognitive function of older adults. The main questions the researchers want to answer are:\n\n* How social are older adults with hearing loss before and after using hearing devices?\n* How well do older adults with hearing loss think before and after using hearing devices?\n* For older adults who have hearing loss and use hearing devices, do changes in social interaction explain changes in how well they think (cognitive function)?\n* Do brainwaves (EEGs) in older adults with hearing loss change after using hearing devices?\n* Are there differences in how social older adults with hearing loss are compared to older adults without hearing loss?\n\nWhat Participants Will Do:\n\n* Participants will take questionnaires for around 60 minutes. Questionnaires will ask participants about their background, health, hearing, and how social they are. Another set of questionnaires will check their thinking ability or cognition.\n* Participants will wear an audio sensor (TILES Audio Recorder on Jelly Mobile phone) for 2 weeks. The sensor will collect and store information about a participant's voice during conversations. Once the device has information about a participant's voice such as pitch and tone it will store this information and delete the audio recording. Words spoken during conversations will be deleted.\n* (Optional) Participants can choose to participate in a 45-60-minute EEG (electroencephalogram) recording session. Participants will have sensors placed on top of their heads. Sensors will record the participants' brainwaves. Sounds will be played to see how participants' brainwaves change when they hear sounds. Eligible participants will be invited to participate in 4-month follow-up study.",[27],[55,56,57,58],"hearing loss","cochlear implant","social engagement","cognition","NOT_YET_RECRUITING","2026-06-17",{"date":62,"type":32},"2026-06-22",{"date":64,"type":21},"2027-07-01",{"date":66,"type":21},"2030-12-31",{"name":68,"class":69},"University of Southern California","OTHER",1,{"id":72,"slug":73,"hasResults":11,"nctId":74,"briefTitle":75,"officialTitle":75,"acronym":4,"eligibilityCriteria":76,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":77,"enrollmentInfo":78,"targetDuration":4,"studyType":22,"phases":80,"briefSummary":81,"conditions":82,"keywords":85,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":70},"100610535","effectiveness-comparison-of-3d-printed-and-conventional-ear-tip-comfort-in-individuals-with-hearing-loss-100610535","NCT07228845","Effectiveness Comparison of 3D-Printed and Conventional Ear Tip Comfort in Individuals With Hearing Loss","Inclusion Criteria:\n\n* Bilateral, symmetric, sensorineural hearing loss, with thresholds between normal and severe degree of hearing loss\n* Normal otoscopy: patent ear canals with normal appearing eardrums and aerated middle ear, bilaterally.\n* English speaking.\n\nExclusion Criteria:\n\n* Self reported history of extensive or current outer or middle ear pathology.\n* Self reported history of extensive outer or middle ear surgery.\n* Self reported history of neurological or cognitive disorder.\n* Active ear infection","89 Years",{"count":79,"type":21},32,[24],"Access to affordable and timely hearing healthcare remains a major challenge for many individuals, partly due to the high cost and long turnaround time. This study will explore whether 3D-printed ear tips perform as well as or better than standard ear tips in terms of sound quality, comfort, and fit over a prolonged duration in a sample of individuals with bilateral hearing loss. It will also compare how long each method takes to make and how much each costs.",[83,27,84],"Hearing Aids","3D Printing",[86,87,55],"hearing aids","3D printing","2026-04-30",{"date":90,"type":32},"2026-05-01",{"date":92,"type":32},"2026-03-15",{"date":94,"type":21},"2027-04-25",{"name":96,"class":69},"University of Arizona",{"id":98,"slug":99,"hasResults":11,"nctId":100,"briefTitle":101,"officialTitle":102,"acronym":4,"eligibilityCriteria":103,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":104,"targetDuration":4,"studyType":22,"phases":106,"briefSummary":107,"conditions":108,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":111,"lastUpdatePostDateStruct":112,"startDateStruct":114,"completionDateStruct":116,"leadSponsor":118,"locationsCount":70},"100610329","hearing-aid-benefit-in-real-world-noisy-environments-100610329","NCT07226167","Hearing Aid Benefit in Real-World Noisy Environments","Evaluating the Impact of Hearing Aid Signal Enhancement Algorithms in Real-World Contexts","Inclusion Criteria:\n\n* Over 18 years old\n* Symmetrical, bilateral, adult onset, sensorineural hearing loss\n* Experienced hearing aid users (\\> 3 months)\n\nExclusion Criteria:\n\n* Under 18 years old\n* Conductive or mixed hearing loss\n* Asymmetrical or unilateral hearing loss\n* Pre-lingual or childhood hearing loss onset\n* No hearing aid experience",{"count":105,"type":21},45,[24],"Researchers are doing this study to understand why hearing aids often work well in controlled laboratory settings but don't provide the same level of benefit in everyday noisy environments. The questions they hope to answer are:\n\n* What factors contribute to hearing aid benefit in noisy environments\n* What factors limit hearing aid benefit\n* How do real-world factors interact with common hearing aid settings\n\nParticipants will complete:\n\n* Hearing and listening tests\n* Memory and attention assessment\n* Surveys on their Smartphone",[109,27,110],"Hearing Aid","Hearing Loss, Adult-Onset","2026-02-20",{"date":113,"type":32},"2026-02-24",{"date":115,"type":32},"2026-02-19",{"date":117,"type":21},"2027-01",{"name":119,"class":69},"University of Wisconsin, Madison",{"id":121,"slug":4,"hasResults":11,"nctId":122,"briefTitle":123,"officialTitle":123,"acronym":4,"eligibilityCriteria":124,"healthyVolunteers":47,"sex":17,"minAge":125,"maxAge":126,"enrollmentInfo":127,"targetDuration":4,"studyType":51,"phases":4,"briefSummary":129,"conditions":130,"keywords":4,"overallStatus":59,"whyStopped":4,"lastUpdateSubmitDate":134,"lastUpdatePostDateStruct":135,"startDateStruct":136,"completionDateStruct":137,"leadSponsor":139,"locationsCount":4},"100625339","NCT07421349","Comparison of Pulmonary Functions and Respiratory Muscle Strength Between Children With Hearing Impairment and Healthy Peers","Inclusion Criteria For Children With Hearing Loss Group:\n\n* Aged between 7 and 16 years\n* Diagnosed with hearing loss\n* No neurological or orthopedic disorders\n* No syndrome and\u002For disease causing intellectual disability, developmental disorder, or visual impairment\n* No use of medication affecting respiratory function within the last 3 months\n* Written informed consent obtained from parent or legal guardian\n\nFor Healthy Control Group:\n\n* Aged between 7 and 16 years\n* No hearing impairment\n* No neurological or orthopedic disorders\n* No syndrome and\u002For disease causing intellectual disability, developmental disorder, or visual impairment\n* No use of medication affecting respiratory function within the last 3 months\n* Written informed consent obtained from parent or legal guardian\n\nExclusion Criteria (Both Groups)\n\n* Intellectual disability preventing participation in assessment procedures\n* Presence of chronic respiratory disease\n* Inability to perform pulmonary function or respiratory muscle strength tests properly","7 Years","16 Years",{"count":128,"type":21},30,"This study aims to compare pulmonary function and respiratory muscle strength between children with hearing impairment and their healthy peers. Hearing plays a critical role not only in communication but also in cognitive, sensory, and psychomotor development. Children with hearing impairment may experience balance and coordination problems, vestibular dysfunction, and reduced muscle strength, which may negatively affect respiratory function.\n\nAlthough several studies have evaluated pulmonary function in children with hearing impairment, research investigating respiratory muscle strength in this population is limited. To our knowledge, no peer-reviewed study has directly compared respiratory muscle strength between children with hearing impairment and healthy controls.\n\nThis study will compare spirometric parameters and respiratory muscle strength measurements between children with hearing impairment and age-matched healthy controls.",[27,131,132,133],"Pulmonary Function","Respiratory Muscle Strength","Children","2026-02-12",{"date":115,"type":32},{"date":111,"type":21},{"date":138,"type":21},"2026-03-30",{"name":140,"class":69},"Bezmialem Vakif University"]