[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"hearing-loss-bilateral\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:hearing-loss-bilateral":34},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,53,76,99],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":35,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":41,"lastUpdatePostDateStruct":42,"startDateStruct":45,"completionDateStruct":47,"leadSponsor":49,"locationsCount":52},"100520607","preschool-hearing-screening-100520607",false,"NCT06058767","Preschool Hearing Screening","Pure-tone Audiometry Versus Otoacoustic Emissions for Preschool Hearing Screening","Inclusion Criteria:\n\n1. Age 2:0 - 6:0 years\n2. Enrolled in a community-based preschool program\n\nExclusion Criteria:\n\n1. Known permanent HL, by parental or school report\n2. Use of a hearing assistive device\n3. Parent does not consent for hearing screening\n4. Child was screened previously for this study\n5. Child is not present in preschool on day of hearing screening","ALL","2 Years","6 Years",{"count":20,"type":21},13764,"ESTIMATED","INTERVENTIONAL",[24],"NA","Children who are deaf or hard-of-hearing (D\u002FHH) are at risk of speech and language delays, which can be mitigated through early identification and intervention. Identifying hearing loss (HL) during preschool is crucial, but the most effective hearing screening method for preschoolers remains uncertain. The purpose of this study is to learn whether, compared to the gold-standard two-stage Pure-tone audiometry (PTA) + otoacoustic emissions (OAE) screening (TS-PO), single-stage OAE (SS-O) screening alone is not inferior at identifying hearing loss when performed in a community-based preschool setting. This study holds the potential to improve early hearing loss detection and intervention among D\u002FHH children, reducing the likelihood of speech and language delays.\n\nA diverse group of 13,764 preschool-age children across community-based preschool centers will be recruited. The intervention involves all subjects undergoing both PTA and OAE screening, with the order determined through randomization. Children who show potential hearing issues based on screening results or teacher concerns will receive further testing to determine the final hearing outcome. Group allocation will be post-hoc, based on their screening results.\n\nIn addition to the primary objective, the study will compare other hearing screening measures and outcomes between the two methods (TS-PO and SS-O). This approach aims to reflect the real-life effectiveness of hearing screening in a diverse population. Ultimately, the study seeks to provide insights into an optimal hearing screening method that could prevent speech and language delays among D\u002FHH children.",[27,28,29,30,31,32,33,34],"Hearing Loss","Hearing Disorders in Children","Hearing Loss, Sensorineural","Hearing Loss, Conductive","Hearing Loss, Unilateral","Hearing Loss, Noise-Induced","Hearing Loss, Mixed","Hearing Loss, Bilateral",[27,13,36,37,38,39],"Otoacoustic Emissions","Pure-Tone Testing","Childhood Hearing Screening","Childhood Hearing Loss","RECRUITING","2026-01-29",{"date":43,"type":44},"2026-02-02","ACTUAL",{"date":46,"type":44},"2023-10-01",{"date":48,"type":21},"2028-02-01",{"name":50,"class":51},"University of California, San Francisco","OTHER",1,{"id":54,"slug":55,"hasResults":11,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":4,"eligibilityCriteria":59,"healthyVolunteers":11,"sex":16,"minAge":60,"maxAge":61,"enrollmentInfo":62,"targetDuration":4,"studyType":22,"phases":64,"briefSummary":65,"conditions":66,"keywords":4,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":52},"100582185","sentence-shaping---dhh-100582185","NCT06860022","Sentence Shaping - DHH","Sentence Shaping: Written Language Intervention for Deaf and Hard of Hearing Middle Schoolers","Inclusion Criteria:\n\n* Children in grades five through eight\n* deaf or hard of hearing\n* use spoken English and American Sign Language (ASL)\n* bilateral hearing loss\n* the ability to read and understand the grammatical structures of interest\n* already be writing sentences, but demonstrate errors in word order and\u002For grammar.\n\nExclusion Criteria:\n\n* diagnosis of dyslexia\n* uncorrected vision impairment (i.e., identified vision loss without use of corrective lenses that interferes with eligibility evaluation tasks)\n* evidence of severe motor impairment (i.e., insufficient motor skills to complete eligibility evaluation tasks independently).","9 Years","15 Years",{"count":63,"type":21},30,[24],"The proposed research addresses a long-standing and important challenge of improving literacy skills of children who are deaf and hard of hearing, a historically under researched group. The investigators aim to leverage shape coding - an empirically validated intervention approach for constructing sentences in spoken English - for improving how efficiently children who are deaf and hard of hearing learn to correctly construct sentences in written English. To advance the promising yet underutilized research on shape coding, the investigators complete the next logical step of applying the visual supports provided with shape coding to written language for deaf and hard of hearing children. Shape coding has been effective for teaching sentence structure in spoken English to children with language disabilities and has recently been applied to sentence structure in American Sign Language with deaf and hard of hearing children. Intervention involving shape coding is predicted to result in increased accuracy of word order in sentences in written English because deaf and hard of hearing children often benefit from visual information. The investigators will accomplish this aim using single case multiple probe across participants design studies with 30 fifth through eighth grade children who are deaf and hard of hearing. The knowledge gained will guide language and literacy intervention for children who are deaf and hard of hearing.",[34],"2025-10-20",{"date":69,"type":44},"2025-10-22",{"date":71,"type":44},"2025-08-28",{"date":73,"type":21},"2026-10",{"name":75,"class":51},"Vanderbilt University",{"id":77,"slug":78,"hasResults":11,"nctId":79,"briefTitle":80,"officialTitle":80,"acronym":4,"eligibilityCriteria":81,"healthyVolunteers":11,"sex":16,"minAge":82,"maxAge":83,"enrollmentInfo":84,"targetDuration":4,"studyType":22,"phases":86,"briefSummary":87,"conditions":88,"keywords":4,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":98},"100416838","clinical-utility-of-residual-hearing-in-the-cochlear-implant-ear-100416838","NCT04707885","Clinical Utility of Residual Hearing in the Cochlear Implant Ear","Inclusion Criteria:\n\n1. Provision of signed and dated informed consent form.\n2. Adults, males and females, ages 18 -79 who have a bilateral sensorineural hearing loss with postlingual onset.\n3. Minimum of 30 days experience with appropriately fit binaural amplification (standardized National Acoustic Laboratories (NAL) fitting method) verified with real ear measurements within 5 dB SPL of targets.\n4. Limited benefit from conventional amplification in the best aided condition as defined by test scores of:\n\n   1. The ear to implanted: Consonant-nucleus-consonant (CNC) words ≤ 60% or AzBio sentences (+10, +5 dB SNR ≤ 60% correct)\n   2. Contralateral ear: ≤ 80% on CNC words or AzBio sentences (+10, +5 dB SNR ≤ 80% correct)\n5. Low frequency Pure Tone Average (PTA- 125, 250, 500 Hz) ≤ 55 dB HL in the ear to be implanted.\n6. Severe to profound mid to high-frequency sensorineural hearing loss (threshold average of 1000, 2000, 3000, and 4000 Hz ≥75 dB HL) in the ear to be implanted.\n7. Low frequency PTA ≤ 55 dB HL sloping to moderately severe to profound mid-to high frequency sensorineural hearing loss (threshold average of 1000, 2000, 3000, 4000 Hz ≥ 60 dB) in the contralateral ear.\n8. Proficient in English.\n9. Undergoing implantation with a current generation CI device from either Cochlear Limited or Advanced Bionics AG.\n\n   1. Cochlear Limited devices include: Nucleus CI612, CI622, CI632, CI624\n   2. Advanced Bionics AG devices include: HiFocus SlimJ, Mid-Scala\n10. Stated willingness and ability to complete testing and all associated study visits.\n\nExclusion Criteria:\n\n1. Previous cochlear implantation.\n2. Prelingual onset of hearing loss.\n3. Abnormal inner ear anatomy on CT imaging.\n4. Auditory neuropathy spectrum disorder.\n5. Retrocochlear pathology such as a vestibular schwannoma or stroke.\n6. Unwillingness or inability to comply with all investigational requirements including the randomization process.\n7. Additional medical, or social barriers that would prevent completion of all study requirements.\n8. Medical condition contraindicated for surgery.\n9. Device selection of Med El CI (per the patient's selection).","18 Years","79 Years",{"count":85,"type":21},40,[24],"The current study is a randomized multi-center clinical trial that investigates the role an intraoperative hearing monitoring system (electrocochleography) has on helping to save residual hearing in patients undergoing cochlear implantation (CI).",[29,27,34],"2025-09-05",{"date":91,"type":44},"2025-09-12",{"date":93,"type":44},"2021-11-10",{"date":95,"type":21},"2027-12-31",{"name":97,"class":51},"Ohio State University",5,{"id":100,"slug":101,"hasResults":11,"nctId":102,"briefTitle":103,"officialTitle":104,"acronym":4,"eligibilityCriteria":105,"healthyVolunteers":11,"sex":16,"minAge":82,"maxAge":106,"enrollmentInfo":107,"targetDuration":4,"studyType":22,"phases":108,"briefSummary":109,"conditions":110,"keywords":4,"overallStatus":40,"whyStopped":4,"lastUpdateSubmitDate":111,"lastUpdatePostDateStruct":112,"startDateStruct":114,"completionDateStruct":116,"leadSponsor":118,"locationsCount":52},"100601871","speech-understanding-and-listening-effort-benefits-of-hearing-instruments-100601871","NCT07116135","Speech Understanding and Listening Effort Benefits of Hearing Instruments","Speech Understanding and Listening Effort Benefits of Infinio Sphere","Inclusion Criteria:\n\n* Adult 18-95 years\n* N3 or N4 hearing loss\n* Experienced hearing aid user\n* English fluency\n* Cognitively able to complete complex listening tasks\n\nExclusion Criteria:\n\n* Outside of specified age range\n* Vulnerable populations\n* Hearing within normal limits or otherwise not appropriate for hearing instruments under study\n* Inability to read, write, or speak English\n* Inability to complete complex listening tasks","95 Years",{"count":63,"type":21},[24],"The goal of this clinical study is to investigate the benefits of hearing instrument use in adults with hearing loss. The main questions it aims to answer are:\n\nDoes hearing instrument use improve speech understanding and listening effort amount people with hearing loss? Researchers will compare varying models of hearing instruments to see how speech understanding and listening effort are impacted.\n\nParticipants will be asked to wearing varying hearing instruments and participate in lab-based activities to evaluate their speech understanding, listening effort, and subjective preference.",[34],"2025-08-04",{"date":113,"type":44},"2025-08-11",{"date":115,"type":44},"2025-02-05",{"date":117,"type":21},"2025-12",{"name":119,"class":120},"Sonova AG","INDUSTRY"]