[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"hearing-loss-sudden\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:hearing-loss-sudden":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,49],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":22,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":30,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":48},"100475748","sudden-sensorineural-hearing-loss-in-wonju-severance-christian-hospital-100475748",false,"NCT05474963","Sudden Sensorineural Hearing Loss in Wonju Severance Christian Hospital","Prospective Cohort Study of Sudden Sensorineural Hearing Loss in Wonju Severance Christian Hospital","Inclusion Criteria:\n\n* Adult patients over 20 years of age\n* A patient who visited Wonju Severance Christian Hospital, Department of Otolaryngology and was diagnosed with sudden hearing loss as it was confirmed that hearing loss of 30dBHL or more occurred within 3 days at three consecutive frequencies in a pure tone audiometry test.\n* Those who have fully explained the purpose and content of the study and voluntarily agreed to the written consent\n\nExclusion Criteria:\n\n* If the patients do not want to or do not fill out the consent form\n* If treatment is started for sudden hearing loss, but the possibility of other inner ear diseases including Meniere's disease is suspected due to repeated hearing loss, repeated recovery, dizziness, tinnitus, etc.\n* Other cases where it is judged difficult to carry out the clinical trial due to the judgment of the person in charge of the above clinical trial","ALL","20 Years","100 Years",{"count":20,"type":21},1000,"ESTIMATED","6 Months","OBSERVATIONAL","This study is to build a cohort of sudden sensorineural hearing loss (SSNHL) patients. When the patient visited the Department of otolaryngology clinic for hearing loss, we can diagnose the SSNHL following the result of pure tone audiometry and the history of the patient. The cohort is a system that tracks the hearing recovery status, timing, and degree of recovery of patients who received cocktail therapy with or without high-dose steroids, vasodilators, antiviral agents, and intratympanic steroid injections, satellite ganglion block, and hyperbaric oxygen therapy.",[26,27,28,29],"SSNHL(Sudden Sensory Neural Hearing Loss)","Sudden Hearing Loss","Hearing Loss, Idiopathic Sudden Sensorineural","Hearing Loss, Sudden",[31,32,33,34,35],"Hearing Loss","Hearing Loss, sudden","SSNHL","Sudden sensorineural hearing loss","sudden sensory neural hearing loss","RECRUITING","2025-03-23",{"date":39,"type":40},"2025-03-26","ACTUAL",{"date":42,"type":40},"2021-07-14",{"date":44,"type":21},"2035-12-31",{"name":46,"class":47},"Wonju Severance Christian Hospital","OTHER",1,{"id":50,"slug":51,"hasResults":11,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":4,"eligibilityCriteria":55,"healthyVolunteers":56,"sex":16,"minAge":57,"maxAge":58,"enrollmentInfo":59,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":61,"conditions":62,"keywords":4,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":4},"100544199","multi-omics-characteristics-and-prognosis-of-idiopathic-sudden-sensorineural-hearing-loss-100544199","NCT06365775","Multi-omics Characteristics and Prognosis of Idiopathic Sudden Sensorineural Hearing Loss","Multi-omics Characteristics and Prognosis in Patients With Idiopathic Sudden Sensorineural Hearing Loss","Inclusion Criteria:\n\n* Age ≥ 4\n* Participants with SSNHL: unilateral or bilateral sensorineural hearing loss of \\> 30 dB HL (decibel) involving at least 3 continuous test frequencies developing within 72 hours\n* Healthy controls: people with PTA thresholds of all test frequencies ≤ 20 dB HL and without otologic disease in the last 3 months\n* Completed informed consent and promised to finish follow-ups\n\nExclusion Criteria:\n\n* Hearing loss with explicit causes, including noise-induced, Ménière's disease, ototoxicity exposure, mumps infection or history of syphilis infection and so on.\n* A history of head trauma or otologic surgery.\n* Malformation of temporal bone discovered by computed tomography (CT)\n* Retro-cochlear lesion discovered by magnetic resonance imaging (MRI)\n* Pregnant women",true,"4 Years","65 Years",{"count":60,"type":21},400,"The goal of this observational study is to describe the multi-omics characteristics and to learn about the prognostic factors in patients with idiopathic sudden sensorineural hearing loss (SSNHL). The main problems it aims to deal with are:\n\n* if there is a difference in data of exome and targeted sequencing among patients with SSNHL affecting bilateral and unilateral sides, and healthy controls\n* if there is a difference in the parameter of MRI among patients with SSNHL affecting bilateral and unilateral sides, and healthy controls\n* to find out which factor from multi-omics data relates to outcomes of SSNHL\n* to develop the best prognostics model based on the multi-omics data.\n\nParticipants will be received audiological tests, blood specimen collection and radiological examination. Researchers will explore the relationship between the multi-omics data and the prognosis and develop the predictive model.",[63,64,29],"Sudden Sensorineural Hearing Loss","Hearing Loss, Sensorineural","NOT_YET_RECRUITING","2024-04-09",{"date":68,"type":40},"2024-04-15",{"date":70,"type":21},"2024-04-23",{"date":72,"type":21},"2026-11-23",{"name":74,"class":47},"Dan Bing"]