[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"heart-arrest-out-of-hospital\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:heart-arrest-out-of-hospital":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,41,66],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":40},"100642822","increasing-law-enforcement-application-of-automated-external-defibrillators-aeds-for-cardiac-arrest-100642822",false,"NCT07649616","Increasing Law Enforcement Application of Automated External Defibrillators (AED)s for Cardiac Arrest","Increasing Law Enforcement Application of Automated External Defibrillators for Cardiac Arrest","Inclusion Criteria:\n\n* Law enforcement officers from agencies in the greater Portland area served by the Portland Cardiac Arrest Epidemiologic Registry\n* aged 18 years of age and older\n\nExclusion Criteria:\n\n* none","ALL","18 Years",{"count":19,"type":20},30,"ESTIMATED","INTERVENTIONAL",[23],"NA","The goal of this study is to learn if an automated external defibrillator (AED) training adjunct video can improve law enforcement self-efficacy, the likelihood of AED application overall, and decrease disparities in women.\n\nParticipants will be asked to:\n\n* complete a brief initial survey\n* view an AED training adjunct video\n* complete another survey following the video",[26,27],"Heart Arrest, Out-Of-Hospital","Defibrillators","NOT_YET_RECRUITING","2026-06-09",{"date":31,"type":32},"2026-06-16","ACTUAL",{"date":34,"type":20},"2026-07-01",{"date":36,"type":20},"2027-12-31",{"name":38,"class":39},"Wayne State University","OTHER",1,{"id":42,"slug":43,"hasResults":11,"nctId":44,"briefTitle":45,"officialTitle":45,"acronym":46,"eligibilityCriteria":47,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":48,"targetDuration":4,"studyType":21,"phases":50,"briefSummary":51,"conditions":52,"keywords":55,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":57,"lastUpdatePostDateStruct":58,"startDateStruct":60,"completionDateStruct":62,"leadSponsor":64,"locationsCount":40},"100593119","the-effect-of-specialty-care-on-recovery-from-cardiac-arrest-trial-the-sparc-trial-100593119","NCT07002294","The Effect of SPecialty cAre on Recovery From Cardiac Arrest Trial (the SPARC Trial)","SPARC","Inclusion Criteria:\n\n* Out-of-hospital cardiac arrest\n* Resuscitated from cardiac arrest with palpable pulse in the emergency department\n* Treated at one of participating hospital emergency departments\n* Age ≥18 years\n\nExclusion Criteria:\n\n* Known prior advanced directives or decision to limit critical care\n* Known pre-arrest dependent functional status (e.g., living in a skilled nursing facility, hospice or bedbound)\n* Arrest in the emergency department \\>4 hours after arrival\n* Traumatic etiology of arrest\n* Known to have opted-out from the SPARC trial",{"count":49,"type":20},1618,[23],"This randomized clinical trial will determine if adult participants who are in the emergency department after being resuscitated from a cardiac arrest outside of the hospital benefit from care delivered at specialized centers.\n\nThe main question that it will answer is whether transferring participants to a hospital with a specialized cardiac arrest service improves recovery of function after 90 days.\n\nParticipants will receive all usual medical care, but some participants will be offered transfer to a regional cardiac arrest center and others will be offered care at the closest appropriate hospital. Investigators will interview participants after 90 days to assess their recovery.",[53,54,26],"Cardiac Arrest (CA)","Heart Arrest",[56],"cardiac arrest","2026-02-03",{"date":59,"type":32},"2026-02-05",{"date":61,"type":20},"2026-06",{"date":63,"type":20},"2032-01",{"name":65,"class":39},"University of Pittsburgh",{"id":67,"slug":68,"hasResults":11,"nctId":69,"briefTitle":70,"officialTitle":70,"acronym":71,"eligibilityCriteria":72,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":73,"targetDuration":4,"studyType":21,"phases":75,"briefSummary":77,"conditions":78,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":40},"100535421","phase-2-naloxone-for-opioid-associated-out-of-hospital-cardiac-arrest-100535421","NCT06251609","Naloxone for Opioid Associated Out of Hospital Cardiac Arrest","NOPACA","Inclusion Criteria:\n\nPatients will be eligible if all the following criteria are met:\n\n• Adults (age ≥ 18 years) in OHCA per EMS protocol. ACLS interventions have been initiated by EMS: chest compressions, ventilation; • 1st dose of epinephrine given via IV or IO.\n\n•. At risk of OA-OHCA (EMS presumed drug-related OHCA or NACARDI positive for occult OA-OHCA) as described above.\n\nExclusion Criteria:\n\n* EMS plans to administer naloxone, or administration of naloxone by EMS during the same encounter\n* Cardiac arrest apparently caused by trauma, choking, or drowning.\n* Known or apparent pregnancy\n* Patient experiences ROSC prior to study drug administration\n* Prior inclusion in the study\n* Patient has an opt out bracelet or family member states exclusion •. Children less than 18 years old",{"count":74,"type":20},98,[76],"PHASE2","The investigator's long-term goal is to conduct Naloxone for Opioid Associated out of Hospital Cardiac Arrest (NOPACA), a randomized, double blind, controlled trial to determine the efficacy of naloxone vs. placebo in Opioid Associated out of Hospital Cardiac Arrest. The investigative team plan to randomize patients in OHCA to early naloxone administration vs. placebo after initial resuscitation and measure ROSC and survival. Challenges to designing NOPACA include uncertainty regarding: 1) the available pool of participants and number of EMS agencies needed to meet enrollment targets; 2) acceptability among patients, EMS and Emergency Medicine provider stakeholders, and 3) estimates of the study outcomes needed for sample size estimates. Toward obtaining the necessary information to design NOPACA, the investigators propose a pilot RCT of participants at high risk for OA-OHCA to verify a reasonable recruitment rate; treatment fidelity and acceptability; and adequate retention and measurement of outcomes at follow up. The investigators propose incorporating hypothesis testing of the feasibility outcomes to determine progression to a definitive trial.",[26,79,80],"Opioid Overdose","Naloxone","2025-03-07",{"date":83,"type":32},"2025-03-10",{"date":85,"type":20},"2026-11",{"date":87,"type":20},"2028-12-31",{"name":89,"class":39},"University of California, San Francisco"]