[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"heart-arrhythmia\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:heart-arrhythmia":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,50,87],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":31,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":49},"100457650","ablation-of-consecutive-atrial-tachycardia-100457650",false,"NCT05239364","Ablation of Consecutive Atrial Tachycardia","Ablation of CONseCutive atriaL Tachycardia gUided by Ultra-high-DEnsity Mapping","CONCLUDE","Inclusion Criteria:\n\n* Consecutive AT subsequent to prior AF ablation procedure or cardiac surgery\n* Surface ECG-documentation of AT as primary clinical arrhythmia\n* ECG indicating stable, map-able AT (stable activation sequence, and CL stability) with cycle length ≥ 200ms\n\nExclusion Criteria:\n\n* \\\u003C 18 years\n* No previous atrial fibrillation ablation procedure or cardiac surgery\n* Pregnant women or women of childbearing potential without a negative pregnancy test within 48 hours prior to treatment\n* History of hemorrhagic diathesis or other coagulopathies\n* Contraindications for oral anticoagulation\n* Hyper- or hypothyroidism\n* Has any condition that would make participation not be in the best interest of the subject","ALL","18 Years",{"count":20,"type":21},100,"ESTIMATED","INTERVENTIONAL",[24],"NA","Ablation of consecutive atrial tachycardia (AT) after ablation of atrial fibrillation (AF) or cardiac surgery can be challenging due to complex substrate and AT mechanisms. A substantial portion of patients is known to show various tachycardias and recurrences occur in a noticeable number of cases. With the availability of novel ultra-high-density mapping techniques characterization and understanding of AT mechanisms and underlying substrate can be improved. Aim of this prospective, multi-center, randomized study is to compare a standard AT ablation approach versus minimalized ablation of the clinical AT in regards to arrhythmia free survival.",[27,28,29,30],"Heart Arrhythmia","Heart Diseases","Arrhythmias, Cardiac","Atrial Tachycardia",[32,33,34,35,36],"Atrial fibrillation","Atrial tachycardia","Pulmonary vein isolation","Electroanatomical mapping","High density mapping","RECRUITING","2026-04-27",{"date":40,"type":41},"2026-04-30","ACTUAL",{"date":43,"type":41},"2020-12-22",{"date":45,"type":21},"2027-06",{"name":47,"class":48},"Evangelical Hospital Düsseldorf","OTHER",6,{"id":51,"slug":52,"hasResults":11,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":4,"eligibilityCriteria":56,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":57,"enrollmentInfo":58,"targetDuration":4,"studyType":22,"phases":60,"briefSummary":61,"conditions":62,"keywords":69,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":86},"100570460","the-potential-protective-effect-of-using-muscle-relaxants-during-electroporation-ablation-pfa-100570460","NCT06707532","The Potential Protective Effect of Using Muscle Relaxants During Electroporation Ablation (PFA)","The Use of Muscle Relaxants During Electroporation Ablation (PFA) as a Potential Protective Factor Against Damage to Transverse Striated Muscle Tissue and the Heart","Inclusion Criteria:\n\n* Patients with requirement for PFA ablation for cardiac indications and ability to provide informed consent for study participation\n\nExclusion Criteria:\n\n* Patients with allergies to the general anaesthetics used, genetic diseases of the neuromuscular plateau - e.g. Duchenne dystrophy, myasthenia gravis - and patients who do not gived informed consent to participate in the study will be excluded from the study.","90 Years",{"count":59,"type":21},32,[24],"The study aims to improve the safety of the electroporation ablation (PFA) procedure by using muscle relaxants to reduce skeletal muscle damage during the procedure. It will also assess myocardial damage to improve the procedure's quality and speed up recovery after the procedure.",[63,64,27,65,66,67,68],"Kidney Failure, Acute","Myopathy; Drugs","Succinylcholine Sensitivity","Muscle Relaxation","General Anesthetic Drug Adverse Reaction","Projection",[70,71,72,73,74,75,76],"electroporation ablation (PFA)","muscle relaxants","rocuronium","chronic pain","acute kidney failure","chronic heart failure","drug protection","2024-11-26",{"date":79,"type":41},"2024-11-27",{"date":81,"type":41},"2024-08-01",{"date":83,"type":21},"2025-12-01",{"name":85,"class":48},"4th Military Clinical Hospital with Polyclinic, Poland",1,{"id":88,"slug":89,"hasResults":11,"nctId":90,"briefTitle":91,"officialTitle":92,"acronym":93,"eligibilityCriteria":94,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":95,"targetDuration":4,"studyType":97,"phases":4,"briefSummary":98,"conditions":99,"keywords":123,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":135,"lastUpdatePostDateStruct":136,"startDateStruct":138,"completionDateStruct":140,"leadSponsor":142,"locationsCount":144},"100541040","contemporary-cardiac-stimulation-in-clinical-practice-left-biventricular-right-and-conduction-system-pacing-100541040","NCT06324682","ConTempoRary Cardiac Stimulation in Clinical practicE: lEft, BivEntriculAr, Right, and conDuction System Pacing","Evaluation of conTempoRary Cardiac Stimulation in Clinical practicE: lEft, BivEntriculAr, Right, and conDuction System Pacing","TREEBEARD","Inclusion Criteria:\n\n* Indication for cardiac stimulation\n* Having performed the implantation of a device for cardiac stimulation\n\nExclusion Criteria:\n\n* Age \\\u003C 18 years;\n* Pregnancy status;",{"count":96,"type":21},8400,"OBSERVATIONAL","The goal of this observational study is to evaluate the clinical characteristics of patients undergoing permanent cardiac pacing and to compare procedural efficacy and safety of different implantation approaches in the clinical practice of the participating centres. The contribution of non-fluoroscopic anatomical and electrophysiological reconstruction systems to device implantation procedures will also be evaluated.\n\nParticipants \\[patients over 18 years old with an indication to receive a definitive pacemaker\u002Fintracardiac defibrillator implant\\] will receive a permanent cardiac pacing implant as requested according to European Society of Cardiology (ESC) guidelines; the investigators will evaluate procedural efficacy and safety of different implantation approaches.",[29,100,101,102,103,104,105,106,107,108,109,110,111,112,113,114,115,116,117,118,119,120,121,122,27],"Atrioventricular Block","Reduced Systolic Function","Atrial Fibrillation","Bradyarrhythmia","Ventricular Tachycardia","Ventricular Dysfunction","Ventricular Fibrillation","Ventricular Arrythmia","Atrioventricular Nodal Disease","Atrioventricular Conduction Defects","Atrioventricular Block Complete","Atrioventricular Block Incomplete","Atrioventricular Junctional Rhythm","Bundle-Branch Block","Left Bundle-Branch Block","Heart Failure, Systolic","Block;Atrioventricular","Block; Arrhythmic","Block; Mobitz","Block, Heart","Block, Fascicular","Block Branch Bundle Left","Heart Failure，Congestive",[124,125,100,103,105,126,127,128,129,130,131,132,133,110,134,107,106,104],"Pace maker (PM)","Implantable cardioverter defibrillator (ICD)","Cardiac Resynchronization therapy","Conduction System Pacing","His Pacing","Left bundle branch area pacing (LBBAP)","CRT","CSP","Primary prevention","Secondary prevention","Heart failure","2024-03-19",{"date":137,"type":41},"2024-03-22",{"date":139,"type":41},"2023-01-01",{"date":141,"type":21},"2034-12-31",{"name":143,"class":48},"University Hospital of Ferrara",31]