[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"heart-failurecongestive\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:heart-failurecongestive":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,49,79,111],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":18,"targetDuration":21,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":27,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":48},"100529619","the-cardio-share-telemedicine-cross-sector-collaboration-model-for-managing-vulnerable-patients-with-heart-failure-100529619",false,"NCT06176131","The Cardio-share Telemedicine Cross-sector Collaboration Model for Managing Vulnerable Patients With Heart Failure","Implementering af Cardiostafet tværsektoriel Samarbejdsmodel Med Telemedicin for Udsatte Patienter Med Hjertesvigt Som Ikke Kan Deltage i Hjerterehabilitering","ADHFQUAL-BFH","Inclusion Criteria:\n\nPatients admitted with acute decompensated heart failure AND:\n\n* with previous admission with decompensated heart failure in the three-month period prior to the current admission or\n* who have two or more admissions in the 6 months prior to the current admission.\n\nExclusion Criteria:\n\n* Patients who\n\n  * have refused to share their data for health-quality projects\n  * have already ongoing telemedicine management for heart failure","ALL",{"count":19,"type":20},300,"ESTIMATED","6 Months","OBSERVATIONAL","The goal of this observational study is to explore the potential of implementing a telemedicine-based cross-sector collaboration model to manage patients with frequent admissions with decompensated heart failure. The main question(s) it aims to answer are:\n\n* Characterization of conditions that make these patients vulnerable\n* Description of key-elements that makes possible to manage the patients with the cardio-share model\n\nParticipants are:\n\n* Patients - will be helped to use the available telemedicine tools\n* General Practitioners - will be offered teleconferences with cardiologists (chat and video) on demand\n* Community health workers (caregivers at the patient home or in elderly home) - will be guided to assist the patients to use the available telemedicine tools Researchers will compare readmission rates (primary outcome) and quality of life of patients where the cardio-share management model is successfully implemented one year before and after the implementation.",[25,26],"Heart Failure，Congestive","Atrial Fibrillation",[28,29,30,31,32,33,34,35],"heart failure","atrial fibrillation","acute decompensated heart failure","heart failure with reduced ejection fraction","heart failure with preserved ejection fraction","telemedicine","health inequity","cross-sector health management","RECRUITING","2026-01-14",{"date":39,"type":40},"2026-01-16","ACTUAL",{"date":42,"type":40},"2024-01-01",{"date":44,"type":20},"2026-12-31",{"name":46,"class":47},"University Hospital Bispebjerg and Frederiksberg","OTHER",1,{"id":50,"slug":51,"hasResults":11,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":55,"eligibilityCriteria":56,"healthyVolunteers":11,"sex":17,"minAge":57,"maxAge":4,"enrollmentInfo":58,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":60,"conditions":61,"keywords":66,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":48},"100579078","prediction-of-heart-failure-with-machine-learning-100579078","NCT06819618","Prediction of Heart-Failure with Machine Learning","Predicting Heart Failure Recovery by Wearables and Machine Learning","PRE-HF-ML","Inclusion Criteria:\n\n* age over 17\n* HFrEF with LV-EF under 41\n* hospitalized for decompensated heart failure with a) nTproBNP over 1000 AND b) willing to participate AND c) at least one out of three clinical signs (edema, pleural effusion, ascites)\n\nExclusion Criteria:\n\n* life expectancy under 6 months due to non-cardiac conditions\n* inability to use smartwatch\n* severe valvular lesions","18 Years",{"count":59,"type":20},32,"In this monocentric observational study the research question is to what extent data collected via Apple Watch can predict the heart failure status of decompensated HF patients. For this purpose, physiological data from the Apple Watch (such as single-lead electrocardiogram, SpO2, respiratory rate, step count, nighttime temperature, etc.) will be extracted and used as predictor variables to forecast outcomes like risk of decompensation and rehospitalization within the follow-up period. Since this is a data-driven study, additional data collected as part of guideline-compliant treatment will also be included.",[62,63,25,64,65],"Heart Failure with Reduced Ejection Fraction","Heart Failure","Heart Failure Acute","Heart Failure; with Decompensation",[63,67,68,69],"Wearables","Monitoring","Apple Watch","2025-02-09",{"date":72,"type":40},"2025-02-11",{"date":74,"type":40},"2024-04-01",{"date":76,"type":20},"2025-05-31",{"name":78,"class":47},"University Medical Center Goettingen",{"id":80,"slug":81,"hasResults":11,"nctId":82,"briefTitle":83,"officialTitle":83,"acronym":84,"eligibilityCriteria":85,"healthyVolunteers":11,"sex":17,"minAge":57,"maxAge":4,"enrollmentInfo":86,"targetDuration":4,"studyType":88,"phases":89,"briefSummary":91,"conditions":92,"keywords":96,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":102,"lastUpdatePostDateStruct":103,"startDateStruct":105,"completionDateStruct":107,"leadSponsor":109,"locationsCount":48},"100543040","the-role-of-compression-stockings-in-heart-failure-patients-100543040","NCT06350695","The ROle of Compression StocKings in Heart Failure Patients","ROCK-HF","Inclusion Criteria:\n\n* Age 18 years and older\n* Diagnosis of Heart failure NYHA II-III Class A, B, or C.\n* Pitting edema of the lower extremities\n\nExclusion Criteria:\n\n* Peripheral arterial disease with ABI of 0.5 or less\n* Severe decompensated heart failure NYHA IV\n* Unstable acute coronary syndrome\n* Severe valvular stenosis or regurgitation\n* Hypertrophic obstructive cardiomyopathy\n* Unstable arrhythmia without a defibrillator\n* On renal replacement therapy, hemodialysis of peritoneal dialysis\n* Morbid obesity with a BMI \\> 40\n* Pregnancy\n* Lymphedema or Lipoedema\n* Unable to put the compression stockings on by him\u002F herself or a person to do it for the patient\n* Septic phlebitis, acute bacterial, viral or allergic inflammation of the legs\n* Expectancy of life less than 6 months\n* Unable to read or understand English language",{"count":87,"type":20},50,"INTERVENTIONAL",[90],"NA","Congestive heart failure (CHF) occurs when the heart is weak and not able to effectively pump blood to the body. One of the common manifestations of CHF is fluid overload and swelling of the legs. Diuretics or \"water pills\" are usually the treatment for fluid overload and leg swelling; however, in some patients' diuretics are no longer effective or the effectiveness is limited due to poor kidney function. The presence of chronic swelling of the legs could potentially damage the veins; additionally, it could lead to chronic skin changes in the legs and in the worst cases to a leg ulcer. Compression stockings are used in patients with venous diseases to reduce the swelling of the legs and improve mobility and quality of life. Although, there is a theoretical risk that compression stockings might push the fluid of the legs back to the heart and lungs worsening the CHF. The purpose of this study is to determine whether the use of knee-high tight socks (tight stockings with strong compression) vs. knee-high soft socks (soft stockings with minimum compression) are effective in preventing swelling and skin changes and safe in patients with CHF. During the first visit (in-person) a routine medical test will be performed including blood tests, review of the medication doses, current weight, an ultrasound images of the veins, (venous reflux ultrasound), questions about health status and a brief physical exam. The participants will be randomly assigned to receive tight compression vs. soft compression socks. Participants will be asked to wear the socks at least 8 hours a day for 5 days a week. There will be a total of 3 virtual visit (by video or telephone); the first one after one week, then after one month and two months. During the virtual visit participants will be asked about symptoms, current medications and doses, and current weight. The participants are expected to return to the clinic after 3 months for a second in-person visit. During this visit the investigators will ask questions about participant's health, they will perform a brief physical exam of their legs, and check participants weight and medicines; also, a venous ultrasound of the legs, questions about health status will be performed. The duration of the study is 3 months.",[25,93,94,95],"Leg Edema","Venous Insufficiency","Venous Ulcers",[97,98,99,100,101],"compression stockings","congestive heart failure","venous insufficiency","edema of the legs","venous ulcers","2024-09-30",{"date":104,"type":40},"2024-10-02",{"date":106,"type":40},"2024-01-17",{"date":108,"type":20},"2026-01-01",{"name":110,"class":47},"University of Maryland, Baltimore",{"id":112,"slug":113,"hasResults":11,"nctId":114,"briefTitle":115,"officialTitle":116,"acronym":117,"eligibilityCriteria":118,"healthyVolunteers":11,"sex":17,"minAge":57,"maxAge":4,"enrollmentInfo":119,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":121,"conditions":122,"keywords":146,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":158,"lastUpdatePostDateStruct":159,"startDateStruct":161,"completionDateStruct":163,"leadSponsor":165,"locationsCount":167},"100541040","contemporary-cardiac-stimulation-in-clinical-practice-left-biventricular-right-and-conduction-system-pacing-100541040","NCT06324682","ConTempoRary Cardiac Stimulation in Clinical practicE: lEft, BivEntriculAr, Right, and conDuction System Pacing","Evaluation of conTempoRary Cardiac Stimulation in Clinical practicE: lEft, BivEntriculAr, Right, and conDuction System Pacing","TREEBEARD","Inclusion Criteria:\n\n* Indication for cardiac stimulation\n* Having performed the implantation of a device for cardiac stimulation\n\nExclusion Criteria:\n\n* Age \\\u003C 18 years;\n* Pregnancy status;",{"count":120,"type":20},8400,"The goal of this observational study is to evaluate the clinical characteristics of patients undergoing permanent cardiac pacing and to compare procedural efficacy and safety of different implantation approaches in the clinical practice of the participating centres. The contribution of non-fluoroscopic anatomical and electrophysiological reconstruction systems to device implantation procedures will also be evaluated.\n\nParticipants \\[patients over 18 years old with an indication to receive a definitive pacemaker\u002Fintracardiac defibrillator implant\\] will receive a permanent cardiac pacing implant as requested according to European Society of Cardiology (ESC) guidelines; the investigators will evaluate procedural efficacy and safety of different implantation approaches.",[123,124,125,26,126,127,128,129,130,131,132,133,134,135,136,137,138,139,140,141,142,143,144,25,145],"Arrhythmias, Cardiac","Atrioventricular Block","Reduced Systolic Function","Bradyarrhythmia","Ventricular Tachycardia","Ventricular Dysfunction","Ventricular Fibrillation","Ventricular Arrythmia","Atrioventricular Nodal Disease","Atrioventricular Conduction Defects","Atrioventricular Block Complete","Atrioventricular Block Incomplete","Atrioventricular Junctional Rhythm","Bundle-Branch Block","Left Bundle-Branch Block","Heart Failure, Systolic","Block;Atrioventricular","Block; Arrhythmic","Block; Mobitz","Block, Heart","Block, Fascicular","Block Branch Bundle Left","Heart Arrhythmia",[147,148,124,126,128,149,150,151,152,153,154,155,156,133,157,130,129,127],"Pace maker (PM)","Implantable cardioverter defibrillator (ICD)","Cardiac Resynchronization therapy","Conduction System Pacing","His Pacing","Left bundle branch area pacing (LBBAP)","CRT","CSP","Primary prevention","Secondary prevention","Heart failure","2024-03-19",{"date":160,"type":40},"2024-03-22",{"date":162,"type":40},"2023-01-01",{"date":164,"type":20},"2034-12-31",{"name":166,"class":47},"University Hospital of Ferrara",31]