[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"hemianopia\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:hemianopia":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,9,0,[8,56,97,127,156,184,216,240,262],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":33,"overallStatus":43,"whyStopped":4,"lastUpdateSubmitDate":44,"lastUpdatePostDateStruct":45,"startDateStruct":48,"completionDateStruct":50,"leadSponsor":52,"locationsCount":55},"100583352","visual-restoration-using-focused-ultrasound-stimulation-and-immersive-virtual-reality-after-stroke-100583352",false,"NCT06875206","Visual Restoration Using Focused Ultrasound Stimulation and Immersive Virtual Reality After Stroke","LIFU-IVR","Inclusion Criteria:\n\n* ≥ 18 years old of any gender and race\n* Clinical ischemic stroke or hemorrhagic (confirmed by CT or MRI) that occurred \\>= 6-24 months ago\n* Partial or complete homonymous hemianopsia on clinical exam\n\nExclusion Criteria:\n\n* Documented history of severe dementia with or without medication before stroke that affect subject's ability to participate in and be compliant to study protocol\n* Significant upper motor deficits and the subject cannot do IVR sessions at the baseline\n* History of seizures\n* Inability to get a new MRI\n* Presence of any ultrasonic stimulation risk factors: an electrically, magnetically, or mechanically activated metal or nonmetal implant including cardiac pacemaker, intracerebral vascular clips, or any other electrically sensitive support system; non-fixed metal in any part of the body; pregnancy (the effect of ultrasonic stimulation on the fetus is unknown); preexisting scalp lesion or wound or bone defect or hemicraniectomy.\n* Patients will be excluded if they have a previous diagnosis of hemianopsia, a new diagnosis of central retinal ischemic injury, or visual blindness or a history of any other ocular disease.\n* Concerns about the inability to complete study visits\u002Fprocedures by the PI.","ALL","18 Years",{"count":19,"type":20},28,"ESTIMATED","INTERVENTIONAL",[23],"NA","This research will explore if brain stimulation combined with virtual reality therapy improves visual impairment. The stimulation technique is called low-intensity focused ultrasound stimulation (LIFUS). The treatment uses ultrasound to stimulate vision specific parts of the brain. Before this therapy, the participants will get structural brain imaging. Functional brain imaging will be performed before and after the study's completion to measure brain activity response to therapy.\n\nThe purpose of this research study is to evaluate patients who have had a stroke between 6 and 24 months ago with a visual field impairment. The duration of active participation in the study is 1.5 months.",[26,27,28,29,30,31,32],"Stroke","Visual Field Defect","Visual Field Defect Following Cerebrovascular Accident","Hemianopia","Quadrantanopia","Occipital Lobe Infarct","Visual Fields Hemianopsia",[34,35,36,37,38,39,40,41,42],"virtual reality","stroke","visual deficit","chronic stroke","ultrasound stimulation","neuromodulation","stroke recovery","visual field defect","funcational imaging","NOT_YET_RECRUITING","2026-05-19",{"date":46,"type":47},"2026-05-22","ACTUAL",{"date":49,"type":20},"2026-12-01",{"date":51,"type":20},"2027-04",{"name":53,"class":54},"Duke University","OTHER",1,{"id":57,"slug":58,"hasResults":11,"nctId":59,"briefTitle":60,"officialTitle":61,"acronym":4,"eligibilityCriteria":62,"healthyVolunteers":63,"sex":16,"minAge":64,"maxAge":65,"enrollmentInfo":66,"targetDuration":4,"studyType":21,"phases":68,"briefSummary":69,"conditions":70,"keywords":79,"overallStatus":87,"whyStopped":4,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":91,"completionDateStruct":93,"leadSponsor":95,"locationsCount":55},"100519758","vision-loss-impact-on-navigation-in-virtual-reality-100519758","NCT06047717","Vision Loss Impact on Navigation in Virtual Reality","The Impact of Vision Loss on Naturalistic Behavior and Navigation in Virtual Reality","Cortically Blind Group:\n\nInclusion Criteria:\n\n* Residents of the United States or Canada\n* Presence of one-sided stroke or stroke-like damage to primary visual cortex or its immediate afferent white matter sustained within the specified age range of 21 - 75 years (verified by MRI and\u002For CT scans)\n* Reliable visual field defects in both eyes (homonymous defects) as measured by Humphrey or equivalent perimetry.\n* Willing, able, and competent to provide their own informed consent\n* Cognitively able, responsible to understand written and oral instructions in English\n* Emmetropic or else wear corrective contact lenses inside the virtual reality headset\n\nExclusion Criteria:\n\n* Those who have never driven or earned a drivers' license\n* Past or present ocular disease interfering with visual acuity\n* Best corrected visual acuity (BCVA) worse than 20\u002F40 in either eye\n* Sustained damage to the dorsal lateral geniculate nucleus\n* Presence of diffuse, whole-brain degenerative processes\n* Presence of brain damage deemed by study staff to potentially interfere with outcome measures\n* History of traumatic brain injury\n* Documented history of drug\u002Falcohol abuse\n* Diagnosis of cognitive or seizure disorders\n* Diagnosis of one-sided attentional neglect\n\nControl Group:\n\nInclusion Criteria:\n\n* Normal or corrected-to-normal vision, who are between the ages of 21 and 75 years of age, roughly matched to the age of CB subjects enrolled above\n* Competent and responsible, as determined by the Principal Investigator\n* Willing, able, and competent to provide their own informed consent\n* Normal cognitive abilities, be able to understand written and oral instructions in English\n* Emmetropic or else wear corrective contact lenses inside the virtual reality headset\n\nExclusion Criteria:\n\n* Subjects who have never driven or earned a drivers' license\n* BCVA worse than 20\u002F40 in either eye\n* Presence of vision loss from ocular diseases or disorders\n* Presence of a visual field defect\n* Inability to wear corrective contact lenses inside the virtual reality helmet if required to see clearly\n* Subjects with a history of neurological disorders\n* Subjects with a history of TBI\n* Persons who lack the competence or are otherwise unable to perform the visual testing as directed.",true,"21 Years","75 Years",{"count":67,"type":20},40,[23],"The purpose of this research is to better understand the impact of cortically-induced blindness (CB) and the compensatory strategies subjects with this condition may develop on naturalistic behaviors, specifically, driving. Using a novel Virtual Reality (VR) program, the researchers will gather data on steering behavior in a variety of simulated naturalistic environments. Through the combined use of computer vision, deep learning, and gaze-contingent manipulations of the visual field, this work will test the central hypothesis that changes to visually guided steering behaviors in CB are a consequence of changes to the visual sampling and processing of task-related motion information (i.e., optic flow).",[71,30,72,73,29,74,31,75,76,77,78],"Stroke, Ischemic","Hemianopsia, Homonymous","Hemianopia, Homonymous","Hemianopsia","Visual Field Defect, Peripheral","Vision Loss Partial","Quadrantanopsia","Stroke Hemorrhagic",[80,81,82,83,84,85,86,35],"Occipital stroke","Vision loss after stroke","Vision recovery","Vision restoration","Partial vision loss","Homonymous quadrantanopsia","Homonymous quadrantanopia","RECRUITING","2026-01-07",{"date":90,"type":47},"2026-01-09",{"date":92,"type":47},"2023-11-28",{"date":94,"type":20},"2028-10",{"name":96,"class":54},"University of Rochester",{"id":98,"slug":99,"hasResults":11,"nctId":100,"briefTitle":101,"officialTitle":102,"acronym":103,"eligibilityCriteria":104,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":105,"enrollmentInfo":106,"targetDuration":4,"studyType":21,"phases":108,"briefSummary":109,"conditions":110,"keywords":111,"overallStatus":43,"whyStopped":4,"lastUpdateSubmitDate":118,"lastUpdatePostDateStruct":119,"startDateStruct":121,"completionDateStruct":123,"leadSponsor":125,"locationsCount":4},"100617370","screening-and-rehabilitation-of-visual-field-defects-in-post-stroke-patients-100617370","NCT07317739","Screening and Rehabilitation of Visual Field Defects in Post-Stroke Patients","SCRiCaViPS Screening and Rehabilitation of Visual Field Defects in Post-Stroke Patients","SCRiCaViPS","Inclusion Criteria:\n\n1. Patients aged 18 to 99 years with stroke (excluding isolated cerebellar, brainstem, or spinal cord strokes), admitted to Neurology in IRCCS San Martino Polyclinic Hospital with the ability to understand and sign the informed consent for study participation.\n2. Mobility of at least one upper limb.\n\nExclusion Criteria:\n\n1. Presence of cognitive impairment (with an MMSE score less than 24), which limits the understanding of the informed consent or the ability to perform the test.\n2. Difficulty moving both upper limbs.\n3. Presence of ocular comorbidity that could affect visual field assessment before stroke.\n4. Presence of fluent aphasia, neglect, or head and gaze deviation.\n5. Presence of disturbances in the state of consciousness\n6. Presence of delirium","99 Years",{"count":107,"type":20},300,[23],"In this study, the investigators will use a wearable device capable of performing this bedside assessment to evaluate the incidence of visual field loss in post-stroke patients. Furthermore, for those with visual field loss, the investigators will investigate whether integrating multisensory audio-visual rehabilitation into the standard physical rehabilitation protocol can help improve visual field loss compared to standard rehabilitation alone.",[29,28],[112,113,114,115,116,117],"Post stroke visual defects","Screening","Visual field","Rehabilitation","Neurorehabilitation","visual-auditory stimulation","2025-12-19",{"date":120,"type":47},"2026-01-05",{"date":122,"type":20},"2026-01-01",{"date":124,"type":20},"2027-03-31",{"name":126,"class":54},"Fondazione David Chiossone - Impresa Sociale",{"id":128,"slug":129,"hasResults":11,"nctId":130,"briefTitle":131,"officialTitle":132,"acronym":133,"eligibilityCriteria":134,"healthyVolunteers":63,"sex":16,"minAge":64,"maxAge":135,"enrollmentInfo":136,"targetDuration":4,"studyType":138,"phases":4,"briefSummary":139,"conditions":140,"keywords":144,"overallStatus":87,"whyStopped":4,"lastUpdateSubmitDate":148,"lastUpdatePostDateStruct":149,"startDateStruct":151,"completionDateStruct":153,"leadSponsor":155,"locationsCount":55},"100603304","mechanisms-of-visual-restoration-after-occipital-stroke-100603304","NCT07134777","Mechanisms of Visual Restoration After Occipital Stroke","Mechanisms of Visual Restoration After Occipital Stroke (MOVROS)","MOVROS","Cortically Blind Subjects (n=50)\n\nInclusion:\n\n* Subjects between 21 and 80 years of age\n* Subjects must be residents of the United States or Canada\n* Subjects must exhibit unilateral stroke or stroke-like damage to primary visual cortex or its immediate afferent white matter sustained within the specified age range of 21 - 80 years (verified by MRI and\u002For CT scans)\n* Subjects with reliable visual field defects in both eyes (homonymous defects) as measured by Humphrey, MAIA, Goldmann, and\u002For equivalent perimetry. This deficit must be large enough to enclose a 5-deg diameter visual stimulus.\n* Subjects must be able to fixate on visual targets reliably for 1000ms, with jitter over less than 1-deg of visual angle.\n\n  o Note: This will be initially assessed by review of visual field reports as supplied by subjects during the screening process. However, we will be unable to fully assess their fixation ability until they start the psychophysics testing in our lab. If at that time we discover that they are unable to maintain adequate fixation, they will be withdrawn from the study.\n* Subjects must be willing, able, and competent to provide their own informed consent\n* Subjects must have their own home computer (desktop or laptop) and reliable internet access\n* All subjects must have normal cognitive abilities and memory, sufficient to be able to understand and follow written and oral instructions in English, as well as to remember how to complete visual training at home, on their own, as instructed, for several months.\n* Justification: We can only accept English-speaking subjects due to a lack of resources for supporting those who would require interpreter services. As all of our subjects are required to spend 3-5 days in lab with rigorous testing and training requirements, we must be able to communicate clearly and with minimal misunderstandings. This would require for up to 5-full days of in person interpreter services, for which we do not have funding. Additionally, ongoing communications take place by phone, email, and\u002For text as a part of home training (for routine check-ins and technical support for example) in the intervals between laboratory visits. This would require us to essentially have \"on demand\" access to interpreter services, which is simply not feasible.\n* Subjects must be safe and willing to undergo magnetic resonance imaging (MRI) scans\n\nExclusion:\n\n* Subjects who have past or present ocular disease interfering with visual acuity\n* Subjects with best-corrected visual acuity (BCVA) worse than 20\u002F40 in either eye\n* Subjects who have documented or suspected damage to the dorsal Lateral Geniculate Nucleus\n* Subjects who have diffuse whole-brain degenerative processes\n* Subjects who have experienced traumatic brain injury\n* Subjects who have any other brain damage deemed by study staff to potentially interfere with training ability or outcome measures\n* Subjects who have oculomotor defects deemed by study staff to potentially interfere with training ability or outcome measures (i.e., by impairing stable fixation during testing or training)\n* Subjects who have documented history of drug\u002Falcohol abuse\n* Subjects who are currently taking neuroactive medications which would impact training, as determined by PI\n* Subjects who have cognitive, memory or seizure disorders\n* Subjects with one-sided attentional neglect\n* Subjects who lack the competence or are otherwise unable to perform the visual training exercises as directed.\n* Subjects who have contradictions to MRI scanning will be excluded. These contraindications include: a) central nervous system aneurysm clips; b) implanted neural stimulator; c) implanted cardiac pacemaker or defibrillator; d) cochlear implant; e) ocular foreign body (e.g., metal shavings); f) insulin pump; g) metal shrapnel or bullet; h) any implanted device that is incompatible with MRI.\n* Subjects who have conditions that preclude MRI scanning, e.g., morbid obesity, claustrophobia.","80 Years",{"count":137,"type":20},100,"OBSERVATIONAL","This project will collect brain imaging data to quantify the effects of early visual cortex damage and visual training interventions on the structure and function of the residual visual system. Our goal is to improve understanding of the consequences of permanent visual cortex damage in humans, and to understand how visual training impacts the function of the residual visual system to restore perception.",[141,142,76,32,29,143,31],"Cortical Blindness","Stroke Ischemic","Hemianopia Homonymous",[145,146,147],"occipital stroke","vision loss","Homonymous quadranopsia","2025-11-26",{"date":150,"type":47},"2025-12-04",{"date":152,"type":47},"2025-10-17",{"date":154,"type":20},"2029-08-01",{"name":96,"class":54},{"id":157,"slug":158,"hasResults":11,"nctId":159,"briefTitle":160,"officialTitle":161,"acronym":4,"eligibilityCriteria":162,"healthyVolunteers":63,"sex":16,"minAge":17,"maxAge":105,"enrollmentInfo":163,"targetDuration":4,"studyType":21,"phases":165,"briefSummary":166,"conditions":167,"keywords":172,"overallStatus":87,"whyStopped":4,"lastUpdateSubmitDate":175,"lastUpdatePostDateStruct":176,"startDateStruct":178,"completionDateStruct":180,"leadSponsor":182,"locationsCount":55},"100322228","new-non-invasive-modalities-for-assessing-retinal-structure-and-function-100322228","NCT03475173","New Non-invasive Modalities for Assessing Retinal Structure and Function","New Non-invasive Modalities for Assessing Retinal Structure and Function:Preliminary Investigation","Controls:\n\nInclusion:\n\nNormal eye exam in last 2 years\n\nExclusion:\n\nCataract or media opacity that would degrade the imaging of the retina. Mild cataracts are okay. Any abnormalities of the retina or optic nerve that could affect metabolism of the retina outside of normal.\n\nSubjects with Inner Retina Defect:\n\nInclusion:\n\nDefined structural defect to include those with Ischemic optic neuropathy, branch retinal artery occlusion (BRAO), hemianopia or visual field defect that respects the vertical meridian, inherited mitochondrial optic neuropathies such as Leber's and Dominant Optic Neuropathy, other retinopathies or optic neuropathies.\n\nExclusion:\n\nCataract or media opacity that would degrade the imaging of the retina. Mild cataracts are okay.\n\nSubjects with Outer Retinal Defect:\n\nInclusion:\n\nAZOOR (acute zonal occult outer retinopathy) or other focal or diffuse outer photoreceptor loss of function\n\nExclusion:\n\nCataract or media opacity that would degrade the imaging of the retina. Mild cataracts are okay.\n\nThe 450 total is to allow for exclusion of some subjects or in the event that the enrolled subject blinks too much or cannot fixate on a visual target adequately to maintain the same eye position during the short imaging interval. We hope to have a total of 450 (50 controls and 400 patients)",{"count":164,"type":20},500,[23],"This study investigates a new technology to assess the structure and function inside the eye. Retinal imaging of subjects with inner and outer retinal defects to detect areas of abnormal structure and function compared to other visual function tests.",[168,169,29,170,171],"Ischemic Optic Neuropathy","Branch Retinal Artery Occlusion","Leber Hereditary Optic Neuropathy","Acute Zonal Occult Outer Retinopathy",[173,174],"Optic Neuropathy",", Retinopathy","2025-11-18",{"date":177,"type":47},"2025-11-24",{"date":179,"type":47},"2019-05-06",{"date":181,"type":20},"2028-03-01",{"name":183,"class":54},"Randy Kardon",{"id":185,"slug":186,"hasResults":11,"nctId":187,"briefTitle":188,"officialTitle":189,"acronym":190,"eligibilityCriteria":191,"healthyVolunteers":11,"sex":16,"minAge":192,"maxAge":193,"enrollmentInfo":194,"targetDuration":4,"studyType":21,"phases":196,"briefSummary":197,"conditions":198,"keywords":200,"overallStatus":87,"whyStopped":4,"lastUpdateSubmitDate":206,"lastUpdatePostDateStruct":207,"startDateStruct":209,"completionDateStruct":211,"leadSponsor":213,"locationsCount":215},"100604295","vision-on-the-road-vision-rehabilitation-for-driving-after-stroke-100604295","NCT07147660","Vision on the Road: Vision Rehabilitation for Driving After Stroke","Diagnostics and Rehabilitation of Post-stroke Visual Field Loss Using Innovative Visual Field Evaluation. The Impact of Losing Driving Privileges","DRIVE","Inclusion criteria:\n\n* Adults aged 20-85 years with a visual field defect following stroke\n* Norwegian Class 1 driving licence revoked no more than five years ago\n* Speak a Scandinavian language\n* Able to provide written informed consent\n* Motivated and willing to participate in study activities for a total of 20 to 28 weeks\n* Own a personal computer (for digital follow-up and online vision training)\n* Able to travel to Oslo for data collection\n\nExclusion criteria:\n\n* Presence of strabismus and\u002For visual neglect\n* Eye disease or other health conditions that do not meet the health requirements for a Norwegian Class 1 driver's license\n* Cognitive impairment, dementia, severe psychiatric diagnosis, or inability to provide written informed consent","20 Years","85 Years",{"count":195,"type":20},52,[23],"The goal of this clinical trial is to learn if vision training works to improve functional vision in people with visual field loss after stroke. The investigators want to know more about how people perceive their own functional vision and ability to compensate for visual field loss in daily activities.\n\nThe main questions the study aims to answer are:\n\n* Does vision training improve dimensions of functional vision?\n* How does vision training affect the participants's perception of functional vision and the ability to compensate for visual field loss? Researchers will compare the effect of home-based vision training to standard care (no vision training) on functional vision.\n\nParticipants will:\n\n* Participate in home-based vision training or standard care for 8 weeks\n* Be contacted once a week by phone\n* Keep a training diary",[26,199,29],"Visual Field Loss",[26,201,202,203,29,204,205],"Vision rehabilitation","Compensatory strategies","Visual field loss","Loss of drivers license","vision training","2025-08-22",{"date":208,"type":47},"2025-08-29",{"date":210,"type":47},"2025-03-28",{"date":212,"type":20},"2028-02",{"name":214,"class":54},"University of South-Eastern Norway",2,{"id":217,"slug":218,"hasResults":11,"nctId":219,"briefTitle":220,"officialTitle":221,"acronym":222,"eligibilityCriteria":223,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":224,"targetDuration":4,"studyType":21,"phases":226,"briefSummary":227,"conditions":228,"keywords":4,"overallStatus":87,"whyStopped":4,"lastUpdateSubmitDate":231,"lastUpdatePostDateStruct":232,"startDateStruct":234,"completionDateStruct":236,"leadSponsor":238,"locationsCount":55},"100601043","visual-plasticity-following-brain-lesions-100601043","NCT07105358","Visual Plasticity Following Brain Lesions","Vision Improvement Through Behavioral Rehabilitation And Neuroplasticity Training","VIBRANT","A. Stroke, brain tumor, or traumatic brain injury patients\n\nInclusion Criteria:\n\n1. At least 18 years of age.\n2. Capable of providing informed consent and complying with study procedures.\n3. Unilateral or bilateral focal brain damage causing loss of vision.\n4. At least three months post-stroke or traumatic brain injury, or a stable brain tumor within the past year.\n\nExclusion Criteria:\n\n1. Severe CNS diseases or disorders unrelated to the focal lesion, which could interfere with study results.\n2. Severe mental health challenges that could interfere with study results, or current or recent (within the past 6 months) drug or alcohol abuse or addiction as defined by DSM-5.\n3. Vision loss resulting from ocular disease or disorder.\n\nB. Healthy volunteers (age-matched controls):\n\nInclusion Criteria:\n\n1. At least 18 years of age.\n2. Capable of providing informed consent and complying with study procedures.\n\nExclusion Criteria:\n\n1. Any CNS diseases or psychiatric disorders (e.g., epilepsy, schizophrenia) that would interfere with study results.\n2. Previous head injury.\n3. Present or past (within past 6 months) drug or alcohol abuse or addiction based on DSM-5.",{"count":225,"type":20},30,[23],"The VIBRANT (Vision Improvement through Behavioral Rehabilitation And Neuroplasticity Training) study is a prospective, double-blind, crossover design (within-subject) in participants with homonymous hemianopia-a type of visual field loss resulting from damage to the post-chiasmatic visual pathways. It aims to investigate whether transcranial random noise stimulation (tRNS) combined with perceptual learning-based training has potential for improving visual impairments.",[27,26,29,30,141,229,230,75],"Brain Tumor","Traumatic Brain Injury","2025-07-29",{"date":233,"type":47},"2025-08-05",{"date":235,"type":47},"2025-07-17",{"date":237,"type":20},"2028-06-30",{"name":239,"class":54},"Georgetown University",{"id":241,"slug":242,"hasResults":11,"nctId":243,"briefTitle":244,"officialTitle":245,"acronym":246,"eligibilityCriteria":247,"healthyVolunteers":63,"sex":16,"minAge":64,"maxAge":135,"enrollmentInfo":248,"targetDuration":4,"studyType":21,"phases":249,"briefSummary":250,"conditions":251,"keywords":4,"overallStatus":87,"whyStopped":4,"lastUpdateSubmitDate":254,"lastUpdatePostDateStruct":255,"startDateStruct":257,"completionDateStruct":259,"leadSponsor":261,"locationsCount":55},"100525398","effect-of-visual-retraining-after-stroke-100525398","NCT06121219","Effect of Visual Retraining After Stroke","Effect of Visual Retraining on Visual Loss Following Cortical Damage","urochester","Cortically Blind Subjects\n\nInclusion:\n\n* Between 21 and 80 years of age\n* Residents of the United States or Canada\n* Unilateral stroke or stroke-like damage to primary visual cortex or its immediate afferent white matter sustained within the specified age range (21-75 years)\n* Reliable visual field defects in both eyes as measured by Humphrey, MAIA, Goldmann, and\u002For equivalent perimetry, large enough to enclose a 5-deg diameter visual stimulus.\n* Able to fixate on visual targets reliably for 1000ms\n* Must have a home computer (desktop or laptop) and reliable internet access\n* Willing, able, and competent to provide informed consent\n* Normal cognitive abilities, able to understand written and oral instructions in English, and competent and responsible adults in order to complete the visual training at home, independently, as instructed, for several months.\n\nExclusion:\n\n* Past or present eye disease interfering with visual acuity\n* BCVA worse than 20\u002F40 in either eye\n* Damage to the dorsal Lateral Geniculate Nucleus\n* Diffuse whole brain degenerative processes\n* History of traumatic brain injury\n* Any other brain damage deemed by study staff to potentially interfere with training ability or outcome measures\n* Documented history of drug\u002Falcohol abuse\n* Currently taking neuroactive medications which would impact training, as determined by PI\n* Presence of cognitive or seizure disorders\n* One-sided attentional neglect\n* Subjects who lack the competence or are otherwise unable to perform the visual training exercises as directed.\n\nControl Subjects (n = 50)\n\nInclusion:\n\n* Between 21 and 80 years of age\n* Report no history of neurological disorder.\n* Competent and responsible, as determined by the Principal Investigator.\n\nExclusion:\n\n* Presence of damage to the visual system\n* Presence of an active disease process involving their nervous system.\n* Cognitive or seizure disorders\n* Best corrected visual acuity worse than 20\u002F40 in either eye\n* Presence of vision field loss from ocular disease or disorder",{"count":137,"type":20},[23],"This project is intended to collect data using standard clinical tests and psychophysics to quantify the effect of visual cortical damage on the structure of the residual visual system, visual perception, spatial awareness, and brain function. The investigators will also assess the effect of intensive visual retraining on the residual visual system, processing of visual information and the use of such information in real-world situations following damage. This research is intended to improve our understanding of the consequences of permanent visual system damage in humans, of methods that can be used to reverse visual loss, and of brain mechanisms by which visual recovery is achieved.",[76,252,143,29,30,71,253,141],"Vision; Loss, Both Eyes","Stroke - Occipital Infarction","2025-07-10",{"date":256,"type":47},"2025-07-16",{"date":258,"type":47},"2024-09-05",{"date":260,"type":20},"2032-01",{"name":96,"class":54},{"id":263,"slug":264,"hasResults":11,"nctId":265,"briefTitle":266,"officialTitle":267,"acronym":4,"eligibilityCriteria":268,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":269,"enrollmentInfo":270,"targetDuration":4,"studyType":21,"phases":272,"briefSummary":273,"conditions":274,"keywords":276,"overallStatus":87,"whyStopped":4,"lastUpdateSubmitDate":285,"lastUpdatePostDateStruct":286,"startDateStruct":288,"completionDateStruct":290,"leadSponsor":292,"locationsCount":55},"100592583","biofeedback-training-for-hemianopia-100592583","NCT06995313","Biofeedback Training for Hemianopia","Biofeedback Training to Improve Fixation Stability, Visual Function Outcomes, and Quality of Life in Hemianopia Cases","Inclusion Criteria:\n\nHemianopia cases with more than 6 months from the date of the lesion, previously diagnosed accordingly by micro perimetry and other tests as needed, 18-90 years old, ability to follow the visual and auditory stimuli and training instructions.\n\nExclusion Criteria:\n\nPrevious or current treatment for low vision rehabilitation, ocular diseases, other serious clinical conditions not related to the hemianopia, both eyes with media opacity that impairs microperimetry testing, lack of ability to perform the tests and training.","90 Years",{"count":271,"type":20},70,[23],"This is a prospective study that compares biofeedback training on the microperimetry (BT) to a control group in patient s with hemianopia. The patients receive 5 sessions of 20 minutes to stimulate with light and sound the brain in using the best residual area on the visual fields post-brain injury visual loss. Visual tests and quality of life questionnaire are performed pre-and-post-training.",[29,275],"Brain Injuries",[277,278,279,280,281,282,283,284],"hemianopsia","biofeedback training","brain tumor","brain trauma","visual fields","visual loss","low vision","fixation stability","2025-05-20",{"date":287,"type":47},"2025-05-29",{"date":289,"type":47},"2021-12-08",{"date":291,"type":20},"2026-07-08",{"name":293,"class":54},"University Health Network, Toronto"]