[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"hemianopsia-homonymous\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:hemianopsia-homonymous":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,61],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":39,"overallStatus":48,"whyStopped":4,"lastUpdateSubmitDate":49,"lastUpdatePostDateStruct":50,"startDateStruct":53,"completionDateStruct":55,"leadSponsor":57,"locationsCount":60},"100519758","vision-loss-impact-on-navigation-in-virtual-reality-100519758",false,"NCT06047717","Vision Loss Impact on Navigation in Virtual Reality","The Impact of Vision Loss on Naturalistic Behavior and Navigation in Virtual Reality","Cortically Blind Group:\n\nInclusion Criteria:\n\n* Residents of the United States or Canada\n* Presence of one-sided stroke or stroke-like damage to primary visual cortex or its immediate afferent white matter sustained within the specified age range of 21 - 75 years (verified by MRI and\u002For CT scans)\n* Reliable visual field defects in both eyes (homonymous defects) as measured by Humphrey or equivalent perimetry.\n* Willing, able, and competent to provide their own informed consent\n* Cognitively able, responsible to understand written and oral instructions in English\n* Emmetropic or else wear corrective contact lenses inside the virtual reality headset\n\nExclusion Criteria:\n\n* Those who have never driven or earned a drivers' license\n* Past or present ocular disease interfering with visual acuity\n* Best corrected visual acuity (BCVA) worse than 20\u002F40 in either eye\n* Sustained damage to the dorsal lateral geniculate nucleus\n* Presence of diffuse, whole-brain degenerative processes\n* Presence of brain damage deemed by study staff to potentially interfere with outcome measures\n* History of traumatic brain injury\n* Documented history of drug\u002Falcohol abuse\n* Diagnosis of cognitive or seizure disorders\n* Diagnosis of one-sided attentional neglect\n\nControl Group:\n\nInclusion Criteria:\n\n* Normal or corrected-to-normal vision, who are between the ages of 21 and 75 years of age, roughly matched to the age of CB subjects enrolled above\n* Competent and responsible, as determined by the Principal Investigator\n* Willing, able, and competent to provide their own informed consent\n* Normal cognitive abilities, be able to understand written and oral instructions in English\n* Emmetropic or else wear corrective contact lenses inside the virtual reality headset\n\nExclusion Criteria:\n\n* Subjects who have never driven or earned a drivers' license\n* BCVA worse than 20\u002F40 in either eye\n* Presence of vision loss from ocular diseases or disorders\n* Presence of a visual field defect\n* Inability to wear corrective contact lenses inside the virtual reality helmet if required to see clearly\n* Subjects with a history of neurological disorders\n* Subjects with a history of TBI\n* Persons who lack the competence or are otherwise unable to perform the visual testing as directed.",true,"ALL","21 Years","75 Years",{"count":21,"type":22},40,"ESTIMATED","INTERVENTIONAL",[25],"NA","The purpose of this research is to better understand the impact of cortically-induced blindness (CB) and the compensatory strategies subjects with this condition may develop on naturalistic behaviors, specifically, driving. Using a novel Virtual Reality (VR) program, the researchers will gather data on steering behavior in a variety of simulated naturalistic environments. Through the combined use of computer vision, deep learning, and gaze-contingent manipulations of the visual field, this work will test the central hypothesis that changes to visually guided steering behaviors in CB are a consequence of changes to the visual sampling and processing of task-related motion information (i.e., optic flow).",[28,29,30,31,32,33,34,35,36,37,38],"Stroke, Ischemic","Quadrantanopia","Hemianopsia, Homonymous","Hemianopia, Homonymous","Hemianopia","Hemianopsia","Occipital Lobe Infarct","Visual Field Defect, Peripheral","Vision Loss Partial","Quadrantanopsia","Stroke Hemorrhagic",[40,41,42,43,44,45,46,47],"Occipital stroke","Vision loss after stroke","Vision recovery","Vision restoration","Partial vision loss","Homonymous quadrantanopsia","Homonymous quadrantanopia","stroke","RECRUITING","2026-01-07",{"date":51,"type":52},"2026-01-09","ACTUAL",{"date":54,"type":52},"2023-11-28",{"date":56,"type":22},"2028-10",{"name":58,"class":59},"University of Rochester","OTHER",1,{"id":62,"slug":63,"hasResults":11,"nctId":64,"briefTitle":65,"officialTitle":66,"acronym":4,"eligibilityCriteria":67,"healthyVolunteers":11,"sex":17,"minAge":68,"maxAge":69,"enrollmentInfo":70,"targetDuration":4,"studyType":23,"phases":72,"briefSummary":73,"conditions":74,"keywords":79,"overallStatus":48,"whyStopped":4,"lastUpdateSubmitDate":89,"lastUpdatePostDateStruct":90,"startDateStruct":92,"completionDateStruct":94,"leadSponsor":96,"locationsCount":60},"100469827","biofeedback-for-hemianopia-vision-rehabilitation-100469827","NCT05397873","Biofeedback for Hemianopia Vision Rehabilitation","Biofeedback Training to Improve Fixation Stability, Visual Function Outcomes, and Quality of Life in Hemianopia Cases","Inclusion Criteria:\n\n* hemianopia cases previously diagnosed accordingly by microperimetry and other tests as needed\n* 18-90 years old\n* ability to follow the visual and auditory stimuli and training instructions\n\nExclusion Criteria:\n\n* previous or current treatment for low vision rehabilitation\n* ocular diseases\n* other serious clinical conditions not related to the hemianopia physiopathology\n* both eyes with media opacity that impairs microperimetry testing\n* lack of ability to perform the tests and training","18 Years","90 Years",{"count":71,"type":22},32,[25],"Patients with brain injury secondary to stroke, surgery, or trauma frequently suffer from homonymous hemianopia, defined as vision loss in one hemifield secondary to retro- chiasmal lesion. Classic and effective saccadic compensatory training therapies are current aim to reorganize the control of visual information processing and eye movements or, in other words, to induce or improve oculomotor adaptation to visual field loss. Patients learn to intentionally shift their eyes and, thus, their visual field border, into the area corresponding to their blind visual field. This shift brings the visual information from the blind hemifield into the seeing hemifield for further processing. Patients learn, therefore, to efficiently use their eyes \"to keep the 'blind side' in sight\". Biofeedback training (BT) is the latest and newest technique for oculomotor control training in cases with low vision when using available modules in the new microperimetry instruments. Studies in the literature highlighted positive benefits from using BT in a variety of central vision loss, nystagmus cases, and others.The purpose of this study is to assess systematically the impact of BT in a series of cases with hemianopia and formulate guidelines for further use of this intervention in vision rehabilitation of hemianopia cases in general.",[30,75,76,77,78],"Brain Injury","Stroke","Brain Tumor","Brain Trauma",[80,47,81,82,83,84,85,86,87,88],"hemianopsia","brain tumor","brain trauma","visual fields","visual loss","low vision","fixation stability","biofeedback training","MAIA microperimeter","2025-05-05",{"date":91,"type":52},"2025-05-09",{"date":93,"type":52},"2021-12-01",{"date":95,"type":22},"2026-07",{"name":97,"class":59},"University Health Network, Toronto"]