[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"hemiparesis-of-the-upper-limb-following-stroke\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:hemiparesis-of-the-upper-limb-following-stroke":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,55],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":29,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":43,"lastUpdatePostDateStruct":44,"startDateStruct":47,"completionDateStruct":49,"leadSponsor":51,"locationsCount":54},"100611648","evaluating-functional-outcomes-of-3d-printed-splints-in-post-stroke-upper-limb-recovery-100611648",false,"NCT07243314","Evaluating Functional Outcomes of 3D-Printed Splints in Post-Stroke Upper Limb Recovery","3D-splint","Inclusion Criteria:\n\n1. Over 18 years old.\n2. Chronic stroke\n3. Upper limb hemiparalysis\n4. Ability to understand and follow orders and able to provide informed consent (Mini-Mental State Exam (MMSE) \\> 24)\n5. Upper-limb mild to moderate spasticity (Modified Ashworth Scale 1+ to 3 at the wrist).\n6. Not participating in other clinical or research studies at the same time\n\nExclusion Criteria:\n\n1. Had deficits in language or cognitive impairments that were likely to interfere with their cooperation in the study\n2. Deformity or presented with severe upper-limb contractures\n3. Inability to commit to the time requirement of the protocol.\n4. Unilateral neglect","ALL","18 Years",{"count":19,"type":20},100,"ESTIMATED","INTERVENTIONAL",[23],"NA","This study aims to evaluate the upper limb motor recovery using a 3D-printed dynamic orthosis compared to a conventional one as part of a rehabilitation program in individuals with chronic stroke.\n\nThe main question it seeks to answer:\n\nWhich type of dynamic splint (3D-printed or traditional), combined with the task-oriented therapy program, leads to greater improvement in affected upper-limb function, patient satisfaction, and usability in stroke patients? Researchers will compare these two types of dynamic splints.\n\nParticipants will:\n\nReceive 20 sessions of task-oriented therapy combined with either a 3D-printed dynamic splint or a traditional dynamic splint.\n\nVisit the clinic five times a week for a period of four weeks. Undergo assessments before and after the 4-week program.",[26,27,28],"Stroke","Stroke Rehabilitation","Hemiparesis of the Upper Limb Following Stroke",[30,31,32,33,34,35,36,37,38,39,40,41],"stroke","Ischemic Stroke","Hemorrhagic Stroke","Hemiparesis","Splint","Dynamic Splint","Three-Dimensional Printing","3D-Printed Splint","Orthosis","Task-Oriented","Traditional Dynamic Splint","Motor Function","NOT_YET_RECRUITING","2025-11-17",{"date":45,"type":46},"2025-11-21","ACTUAL",{"date":48,"type":20},"2025-11",{"date":50,"type":20},"2027-09-30",{"name":52,"class":53},"King Saud University","OTHER",1,{"id":56,"slug":57,"hasResults":11,"nctId":58,"briefTitle":59,"officialTitle":60,"acronym":61,"eligibilityCriteria":62,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":63,"targetDuration":4,"studyType":21,"phases":65,"briefSummary":66,"conditions":67,"keywords":69,"overallStatus":81,"whyStopped":4,"lastUpdateSubmitDate":82,"lastUpdatePostDateStruct":83,"startDateStruct":85,"completionDateStruct":87,"leadSponsor":89,"locationsCount":54},"100576492","neurophysiological-and-behavioral-effects-of-combining-transcranial-direct-current-stimulation-tdcs-and-modified-constraint-induced-movement-therapy-mcimt-100576492","NCT06786000","Neurophysiological and Behavioral Effects of Combining Transcranial Direct Current Stimulation (tDCS) and Modified-Constraint Induced Movement Therapy (mCIMT)","Neurophysiological and Behavioral Effects of Combining Transcranial Direct Current Stimulation (tDCS) and Modified-Constraint Induced Movement Therapy (mCIMT) on Upper Limb Function Recovery in Patients with Stroke","tDCS and mCIMT","Inclusion Criteria:\n\n1. Adult participants clinically diagnosed and confirmed by imaging of ischemic or hemorrhagic cerebrovascular accident (Dahl et al., 2008; Jin et al., 2019).\n2. Participant's age older than 18 years (Baltar et al., 2020).\n3. Stroke onset more than 3 months with unilateral motor deficits (Lin et al., 2010).\n4. Adequate cognitive function is required to follow instructions. The Arabic version of the Mini Mental State Examination (MMSE) should be ≥24 (Kim, 2021).\n5. 10° of active extension to the metacarpophalangeal and interphalangeal joints and 20° at wrist will be assessed by manual goniometer (Dahl et al., 2008).\n6. Fugl-Meyer assessment (FMA) scores between 19 and 58, indicating moderate to mild impairments.\n7. Not participating in other clinical, or research studies at the same time.\n\nExclusion Criteria:\n\n1. Severe muscle spasticity at the affected limb at all joints (the Modified Ashworth Scale scores \\> 3) (Baltar et al., 2020).\n2. Contraindications to NIBS (Bornheim et al., 2019).\n3. Unilateral neglect (Dahl et al., 2008)\n4. Other neurologic or orthopedic conditions that may affect hand function.\n5. Unstable medical conditions.",{"count":64,"type":20},300,[23],"This clinical trial aims to evaluate the effect of different types of tDCS modulation with mCIMT in improving affected upper-limb motor function for stroke patients. The main question it seeks to answer:\n\nWhich type of tDCS (bi-hemispheric, anodal, or cathodal) combined with the mCIMT program leads to greater improvement in affected upper-limb function in patients with stroke? Researchers will compare these three types of tDCS to a sham tDCS. To see which kind of tDCS protocol combined with the mCIMT program will be more effective in improving affected upper-limb function for stroke patients.\n\nParticipants will:\n\n1. Participants will receive 12 sessions of mCIMT combined with tDCS or mCIMT alone.\n2. Visit the clinic three times a week for four weeks.\n3. Participants will do fMRI and TMS before and after the program and three times of assessment before and after two weeks after the program.",[26,28,68],"Stroke Rehabilitatiom",[30,70,71,72,73,74,75,76,77,78,79,80],"ischemic stroke","hemorrhagic stroke","tDCS","mCIMT","hemiparesis","neural activation","primary motor cortex","NIBS","non invasive brain stimulation","trans direct current stimulation","modified constraint induced movement therapy","RECRUITING","2025-01-14",{"date":84,"type":46},"2025-01-22",{"date":86,"type":46},"2023-04-11",{"date":88,"type":20},"2025-04-11",{"name":52,"class":53}]