[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"hemiparesishemiplegia-one-sided-weaknessparalysis\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:hemiparesishemiplegia-one-sided-weaknessparalysis":34},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,58],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":35,"overallStatus":45,"whyStopped":4,"lastUpdateSubmitDate":46,"lastUpdatePostDateStruct":47,"startDateStruct":50,"completionDateStruct":52,"leadSponsor":54,"locationsCount":57},"100524306","effects-of-atalante-exoskeleton-on-gait-recovery-in-non--or-poorly-ambulatory-patients-with-hemiparesis-in-the-acutesubacute-phase-month-1-to-4-100524306",false,"NCT06107010","Effects of Atalante Exoskeleton on Gait Recovery in Non- or Poorly Ambulatory Patients With Hemiparesis in the Acute\u002FSubacute Phase (Month 1 to 4)","EarlyExo","Inclusion Criteria:\n\n* \\>18 years old\n* First clinically significant disability due to stroke\n* Hemiparesis in acute-subacute phase (1 to 4 months since lesion) due to a stroke\n* Functional Ambulation Category score (FAC) \\\u003C2\n* Patient with health insurance\n* Informed and willing to sign an informed consent form approved by the Ethics Committee. For clarity, if a motor impairment prevents the subject from signing by himself, he\u002Fshe can still be included if the signature can be done by an impartial witness.\n\nExclusion Criteria:\n\n* Muscle overactivity in hip adductors, hamstrings, quadriceps and plantar flexors, which interferes with exoskeleton use, based on clinician investigator's opinion\n* Recent fracture (\\\u003C 3 months) or any therapy inducing secondary osteoporosis\n* Excessive joint mechanical pain in the lower limbs based on clinician investigator's opinion\n* Pressure sore grade I or more over contact zones with Atalante system, according to the International Pressure Ulcer Classification System NPUAP - EPUA\n* Medical contra-indication to medium intensity physical strain\n* Orthostatic hypotension (loss of \\> 20 mmHg systolic BP after 3 minutes in standing position)\n* Uncontrolled seizures\n* Morphological contra-indications to the use of Atalante (as per user's manual)\n* Pregnant woman\n* Adults who lack the capacity to provide informed consent, and all those persons deprived of their liberty in prisons or other places of detention\n* Concurrent participation in another interventional trial","ALL","18 Years",{"count":19,"type":20},66,"ESTIMATED","INTERVENTIONAL",[23],"NA","The present clinical investigation - EarlyExo, is an interventional, international, multicentric, prospective, single-blinded randomized controlled trial.\n\nThis clinical investigation is designed to test the hypothesis that early and intense introduction of walking sessions assisted by the Atalante exoskeleton, in a sample of hemiparetic patients with still non or poor ambulatory capacities (FAC 0 or 1) between one- and four-months post stroke, would result in a better recovery of functional walking compared to a control group only receiving conventional therapy. Improved recovery will be measured through the proportion of patients reaching a FAC score of 4 or higher at the end of the intervention period. The tested hypothesis is that this proportion will be higher in the Exo group.\n\nThe duration of the intervention period in both groups is 6 weeks.\n\n* For the Exo group: 3 sessions per week (i.e., 18 one-hour sessions) with the Atalante device and 2 sessions per week (i.e., 12 one-hour sessions) of conventional therapy.\n* For the Control group: 5 sessions per week of conventional therapy (i.e., 30 one-hour sessions).\n\nThe study will include 66 patients (33 in each arm) and takes place in two French centers, two German centers and one Spanish center.",[26,27,28,29,30,31,32,33,34],"Stroke, Acute","Stroke, Ischemic","Stroke, Subacute","Stroke Hemorrhagic","Cerebrovascular Disorders","Cerebrovascular Accident","Hemiparesis","Hemiparesis;Poststroke\u002FCVA","Hemiparesis\u002FHemiplegia (One Sided Weakness\u002FParalysis)",[36,37,38,39,40,41,42,43,44],"Robotics","Rehabilitation","Powered Exoskeleton","Walking recovery","Stroke","Acute stroke","Subacute stroke","Functional Ambulation Category","Randomized controlled study","RECRUITING","2025-01-30",{"date":48,"type":49},"2025-02-04","ACTUAL",{"date":51,"type":49},"2023-06-12",{"date":53,"type":20},"2026-02-28",{"name":55,"class":56},"Wandercraft","INDUSTRY",5,{"id":59,"slug":60,"hasResults":11,"nctId":61,"briefTitle":62,"officialTitle":63,"acronym":64,"eligibilityCriteria":65,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":66,"enrollmentInfo":67,"targetDuration":4,"studyType":21,"phases":69,"briefSummary":70,"conditions":71,"keywords":73,"overallStatus":45,"whyStopped":4,"lastUpdateSubmitDate":79,"lastUpdatePostDateStruct":80,"startDateStruct":82,"completionDateStruct":84,"leadSponsor":86,"locationsCount":89},"100507442","isokinetic-strength-training-in-hemiparetic-patient-with-knee-extension-thrust-100507442","NCT05887440","Isokinetic Strength Training in Hemiparetic Patient With Knee Extension Thrust","Effects of Isokinetic Strength Training of Knee Flexor and Extensor Muscles on Walking in Hemiparetic Patients With Knee Extension Thrust","ISOWALK","Inclusion Criteria:\n\n* Hemiparetic patient (hemorragic or ischemic stroke)\n* Subacute stage (\\\u003C 6 Months) ou chronic stage of stroke (\\> 6 months) (6 patients in each group)\n* Age between 18 and 75 years\n* Able to walk 10 meters independently without any assistive devices\n* Knee extension thrust during stance phase of gait cycle (rapid posterior movement of the knee toward extension)\n* Scheduled rehabilitation program with isokinetic strength training\n* affiliation to a social security\n* Patients who received and signed informed consent\n\nExclusion Criteria:\n\n* Major comprehension deficit that not allow to give informed consent and participate to isokinetic strength training (assessed with comprehension subscore of Langague screening Test)\n* non stable (unstable cardiovascular condition)\n* musculoskeletal disorders with knee pain that not allowed isokinetic strength training\n* Botulinum toxin injection less than 3 months or repeated injection in lower limb,\n* Proprioception trouble assessed with proprioception section of the Fugl-Meyer Assessment \\[FMA-P\\] 0\u002F2\n* spasticity of triceps surae ≥2 (Modified Ashworth scale)\n* ankle dorsiflexion angle less than 90°\n* pregnant women or breastfeeding\n* persons with safety measure","75 Years",{"count":68,"type":20},12,[23],"The purpose of this study is to assess the impact of an isokinetic strength training of knee flexor and extensor muscles on walking performance in hemiparetic patients with knee extension thrust.",[34,72],"Gait Disorder",[40,74,75,76,77,78],"Extensor thrust","resistance training","Isokinetic","walking speed","rehabilitation","2023-09-01",{"date":81,"type":49},"2023-09-05",{"date":83,"type":49},"2023-08-21",{"date":85,"type":20},"2026-12-01",{"name":87,"class":88},"Rennes University Hospital","OTHER",1]