[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"hemiplegic-cerebral-palsy\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:hemiplegic-cerebral-palsy":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,13,0,[8,44,82,112,140,165,196,222,246,269,295,322,345],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":38,"leadSponsor":40,"locationsCount":43},"100643867","effect-of-plyometric-training-cross-education-on-strength-selective-motor-control-and-balance-in-children-with-hemiplegic-cerebral-palsy-100643867",false,"NCT07669857","Effect of Plyometric Training Cross Education on Strength, Selective Motor Control and Balance in Children With Hemiplegic Cerebral Palsy","PLYO-HCP","Inclusion Criteria:Children eligible for participation in this study must meet all the following criteria:\n\n1. Diagnosed with HCP by a pediatric neurologist.\n2. Age range 6 and 10 years old.\n3. Their grade of spasticity level 1 or 1+ according to MAS.\n4. Their gross motor function level is I, II on GMFCS.\n5. Able to follow verbal instructions and cooperate during assessment and training.\n\nExclusion Criteria:Children will be excluded from this study if they have any of the following:\n\n1. Presence of corrective neurological\u002Fmusculoskeletal surgery of the lower limb in the previous year or botulinum toxin injections of the lower limb within the previous 6 months.\n2. Presence of visual or auditory impairments that would affect balance performance.\n3. Uncontrolled epileptic seizures or recent medication changes","ALL","6 Years","10 Years",{"count":20,"type":21},40,"ESTIMATED","INTERVENTIONAL",[24],"NA","The goal of this clinical trial is to evaluate the effect of plyometric training with cross-education on lower limb muscle strength, selective motor control, and balance in children with hemiplegic cerebral palsy (HCP). It will also assess the safety and feasibility of applying this training program in pediatric rehabilitation.\n\nThe main questions it aims to answer are:\n\nDoes plyometric training with cross-education improve lower limb muscle strength in children with HCP? Does it improve selective motor control in the affected lower limb? Does it improve balance in children with HCP? Researchers will compare a study group receiving conventional physiotherapy plus plyometric training applied to the less affected limb to a control group receiving conventional physiotherapy only.\n\nParticipants will:\n\nReceive treatment for 12 weeks (2 sessions per week) Attend regular physiotherapy sessions including stretching, strengthening, balance, and gait training Participate in plyometric exercises (study group only) Be assessed before and after the intervention using standardized tests for muscle strength, selective motor control, and balance",[27],"Hemiplegic Cerebral Palsy",[29,30,31],"Cross-education effect","Hemiplegic cerebral palsy","Plyometric training","NOT_YET_RECRUITING","2026-06-21",{"date":35,"type":36},"2026-06-25","ACTUAL",{"date":35,"type":21},{"date":39,"type":21},"2026-09-30",{"name":41,"class":42},"Cairo University","OTHER",3,{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":50,"eligibilityCriteria":51,"healthyVolunteers":11,"sex":16,"minAge":52,"maxAge":53,"enrollmentInfo":54,"targetDuration":4,"studyType":22,"phases":56,"briefSummary":57,"conditions":58,"keywords":59,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":72,"lastUpdatePostDateStruct":73,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":81},"100639626","spinal-cord-associative-plasticity-in-cerebral-palsy-100639626","NCT07607665","Spinal Cord Associative Plasticity in Cerebral Palsy","Paired Stimulation of Hand Motor Cortex and Median Nerve to Induce Spinal Cord Plasticity in Hemiplegic Cerebral Palsy","SCAP-CP","Inclusion Criteria:\n\n* Maintenance of caffeine and exercise levels at time of sessions\n* Ability to provide informed consent\n* Manual ability classification system (MACS) level I to III\n\nExclusion Criteria:\n\n* History of seizures in last two years\n* Use of medications that lower seizure threshold\n* History of implanted equipment including stimulators\u002Fpacemakers","18 Years","80 Years",{"count":55,"type":21},25,[24],"Associative plasticity has been used to promote functional recovery from conditions affecting movement. The long term goal of this project is to use electrical stimulation techniques to improve arm and hand function. The goal of this prospective experimental study in adults with hemiplegic cerebral palsy (hCP) is to test the effects of pairing hand motor cortical and median nerve stimulation targeted to induce plasticity in the cervical spinal cord. Based on preliminary data in neurotypical adults, the investigators are testing the effects of this approach in adults with hCP.\n\nThis study will first verify the present stimulation parameters as sufficient to promote induction of associative plasticity of sensorimotor connections for manual dexterity in adults with hCP. This will be assessed through neurophysiological, biomechanical, and clinical functional outcome measures. Successful pairing showing meaningful improvements in dexterity could then be used as an impetus for a larger study examining the efficacy of SCAP in people with hCP.",[27],[60,61,62,63,64,65,66,67,68,69,70],"cervical spinal cord","spinal cord associative plasticity","SCAP","corticospinal","manual dexterity","cerebral palsy","motor evoked potential","hemiplegia","adults with CP","sensory","somatosensation","RECRUITING","2026-05-26",{"date":74,"type":36},"2026-05-28",{"date":76,"type":21},"2026-06",{"date":78,"type":21},"2032-05",{"name":80,"class":42},"Columbia University",1,{"id":83,"slug":84,"hasResults":11,"nctId":85,"briefTitle":86,"officialTitle":87,"acronym":88,"eligibilityCriteria":89,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":90,"enrollmentInfo":91,"targetDuration":4,"studyType":22,"phases":93,"briefSummary":94,"conditions":95,"keywords":99,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":103,"lastUpdatePostDateStruct":104,"startDateStruct":106,"completionDateStruct":108,"leadSponsor":110,"locationsCount":81},"100551020","a-motor-learning-intervention-to-target-walking-performance-in-ambulant-children-with-cerebral-palsy-100551020","NCT06454656","A Motor Learning Intervention to Target Walking Performance in Ambulant Children With Cerebral Palsy","A \"MOtor Learning Based Intervention for Lower Extremities (MOBILE)\" to Target Walking Performance in Ambulant Children With Cerebral Palsy: A Feasibility Study","MOBILE","Inclusion Criteria:\n\n* Primary diagnosis of Cerebral Palsy (GMFCS Levels I-III)\n* Has a specific walking related goal\n* Has capacity to follow instruction\n* Has a primary caregiver who can support a home program\n\nExclusion Criteria:\n\n* Has had surgery within 6 months of intervention start date\n* Has had botox\u002F baclofen within 3 months of intervention start date\n* Has a dual diagnosis that impacts ability to follow instruction\n* Has a significant cognitive impairment","17 Years",{"count":92,"type":21},14,[24],"The goal of this clinical trial is to learn if a new therapy approach to improve walking ability in children with Cerebral Palsy is acceptable to the children and the families in a community setting.\n\nThe main questions we look to answer are:\n\n1. Do the children\u002Fteens tolerate the therapy and feel that it is helpful?\n2. Do the parents\u002F families feel the therapy helps and is easy to commit to?\n3. Do the children\u002Fteens complete all their therapy sessions and assessments as planned?\n\nThe participants will trial the therapy for 30 hours over 6 weeks and will perform assessments before and after to see if they meet their goals. They will also be interviewed to see how they felt about the therapy when they finish.",[96,97,98,27],"Cerebral Palsy","Walking, Difficulty","Spastic Diplegia",[100,101,102],"Motor Learning Theory","Neuroplasticity","Neurological Rehabilitation","2026-04-09",{"date":105,"type":36},"2026-04-14",{"date":107,"type":36},"2024-08-12",{"date":109,"type":21},"2027-06",{"name":111,"class":42},"Royal College of Surgeons, Ireland",{"id":113,"slug":114,"hasResults":11,"nctId":115,"briefTitle":116,"officialTitle":117,"acronym":4,"eligibilityCriteria":118,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":90,"enrollmentInfo":119,"targetDuration":4,"studyType":22,"phases":121,"briefSummary":122,"conditions":123,"keywords":125,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":131,"lastUpdatePostDateStruct":132,"startDateStruct":134,"completionDateStruct":136,"leadSponsor":138,"locationsCount":43},"100615188","bootle-blast-pilot-randomized-controlled-trial-100615188","NCT07289360","Bootle Blast: Pilot Randomized Controlled Trial","Testing a Mixed-Reality Video Game for Home-Based Practice of Arm-Hand Skills for Children With Cerebral Palsy: A Pilot Randomized Controlled Trial","Inclusion Criteria:\n\n* Diagnosis of hemiplegic Cerebral Palsy\n* MACS levels I (handles objects easily) to III (handles objects with difficulty)\n* Aged 6 to 17 years with sufficient cognitive capacity and cooperation to play Bootle Blast and complete outcome assessments\n* Ability to communicate in English\n* Able to travel to Holland Bloorview, Grandview or CHEO and complete a total of 3 in-person study appointments\n* Has a large screen (e.g. TV) with an appropriate play space (3m x 3m) in front\n* At least intermittent access to the internet\n* Have time to play Bootle Blast for 15-20 minutes\u002Fday, 3-4 days\u002Fweek for 12 weeks.\n\nExclusion Criteria:\n\n* Received upper limb surgery, botulin toxin injections in the past 4 months, or constraint therapy\u002Fcasting in the previous 3 months that may be associated with changing abilities\n* Currently or anticipates receiving active treatments impacting upper limb function during the study period\n* Uncontrolled epilepsy that may be triggered by video game play\n* Medical condition impeding safe participation in physical activity associated with Bootle Blast\n* Visual limitations that interfere with Bootle Blast play",{"count":120,"type":21},46,[24],"One in 500 Canadians has cerebral palsy (CP), a lifelong condition affecting movement and function. Physical and occupational therapies greatly benefit children with CP but can be costly and difficult to access. Children, parents, and clinicians are interested in using movement-tracking video games for home-based hand\u002Farm therapy. Yet, the technologies and evidence to support this approach are limited. We partnered with key stakeholders and an interdisciplinary team to co-create Bootle Blast. Bootle Blast tracks skeletal movements and interactions with real-life objects, engaging children in individualized play experiences rich in feedback, task specificity, and opportunities for goal-directed motor practice linked to meaningful activities.\n\nTo establish Bootle Blast's clinical effectiveness, a large-scale randomized controlled trial (RCT) is needed. Pilot RCTs provide important insights that position large-scale RCTs for success. As a result, the goal of this Pilot RCT is to test whether a mixed-reality video game intervention (i.e. Bootle Blast) can improve upper-limb function, activity, and participation in children and youth aged 6-17 years with hemiplegic cerebral palsy. The main questions it aims to answer are: (1) Is it feasible and acceptable for families to use Bootle Blast at home for 12 weeks? (2) Does the intervention show preliminary improvements in hand-arm motor outcomes compared to usual care?\n\nResearchers will compare an immediate Bootle Blast intervention group to a waitlist comparison group that continues usual care for 12 weeks to see whether access to Bootle Blast leads to increased practice, greater engagement, and improved motor outcomes.\n\nParticipants will:\n\nComplete three in-person assessments (baseline, 12 weeks, 24 weeks) with standardized motor and participation measures.\n\nBe randomized to begin 12 weeks of home-based Bootle Blast immediately or after a 12-week waitlist period.\n\nUse the Bootle Blast game at home for 15-20 minutes per day, 3-4 days per week, with all gameplay tracked automatically.\n\nA subset of participants will also receive weekly 10-minute support calls from a monitoring coach.",[124,27],"Cerebral Palsy (CP)",[126,127,128,129,130],"Home-Based Rehabilitation","Interactive Video Game Therapy","Digital Therapeutics","Tele-Rehabilitation","Gamified Rehabilitation","2026-01-06",{"date":133,"type":36},"2026-01-08",{"date":135,"type":36},"2025-12-06",{"date":137,"type":21},"2027-01",{"name":139,"class":42},"Holland Bloorview Kids Rehabilitation Hospital",{"id":141,"slug":142,"hasResults":11,"nctId":143,"briefTitle":144,"officialTitle":145,"acronym":4,"eligibilityCriteria":146,"healthyVolunteers":11,"sex":16,"minAge":147,"maxAge":148,"enrollmentInfo":149,"targetDuration":4,"studyType":22,"phases":151,"briefSummary":152,"conditions":153,"keywords":154,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":156,"lastUpdatePostDateStruct":157,"startDateStruct":159,"completionDateStruct":161,"leadSponsor":163,"locationsCount":81},"100611707","kinesiotherapy-on-upper-limb-function-and-activities-of-daily-living-in-children-with-hemiplegic-cerebral-palsy-100611707","NCT07244081","Kinesiotherapy on Upper Limb Function and Activities of Daily Living in Children With Hemiplegic Cerebral Palsy","Effects of Kinesiotherapy on Upper Limb Function and Activities of Daily Living in Children With Hemiplegic Cerebral Palsy","Inclusion Criteria:\n\n* Age: 8-13 years old both sexes\n* Ability to follow simple instructions, able to sit or stand with support to participate in physical therapy sessions( MACS level Ⅰ-Ⅲ)(9) and (GMFCS level Ⅰ-Ⅲ)(10)\n* Ability to communicate needs and discomfort (verbally or non-verbally)\n* No concurrent participation in other physical therapy or rehabilitation programs\n\nExclusion Criteria:\n\n* Severe visual and hearing impairments that would hinder participation\n* Severe cognitive or intellectual disabilities that would impede understanding of instructions\n* History of seizures or other neurological conditions that may impact participation\n* Recent (within 6 months) or planned orthopedic surgery\n* Concurrent use of botulinum toxin injections or oral medications affecting muscle tone(2).","8 Years","13 Years",{"count":150,"type":21},28,[24],"This study will be randomized controlled trial, data will be collected from BASES special education school sialkot , Allama Iqbal Memorial Hospital, sialkot and Lahore. The study will include 28 patients equally divided into two groups and randomly allocated. Inclusion criteria for the study will be age of 8-13 years old of both sexes, ability to follow simple instructions, able to sit or stand with support to participate in physical therapy sessions( MACS level Ⅰ-Ⅲ) and (GMFCS level Ⅰ-Ⅲ), ability to communicate needs and discomfort (verbally or non-verbally), No concurrent participation in other physical therapy and excluded with Severe visual and hearing impairments, severe cognitive disabilities, History of seizures, Recent (within 6 months) or planned orthopedic surgery, Concurrent use of botulinum toxin injections. Experimental group will perform both Kinesiotherapy protocol and conventional physical therapy while Control group will perform only conventional physical therapy for 8 weeks 2-3 times weekly with 45 min of each session. Outcomes to be analyzed will be upper limb function and Activities of daily living (ADLs). Tools used for data collection will be Action Research Arm (ARA) test, Pediatric Evaluation of Disability Inventory (PEDI). Data will be analyzed through SPSS version 26, 27.",[27],[155],"Kinesiotherapy, Hemiplegic Cerebral Palsy, Upper limb function, ADLs","2025-11-17",{"date":158,"type":36},"2025-11-24",{"date":160,"type":36},"2025-10-22",{"date":162,"type":21},"2026-01-30",{"name":164,"class":42},"Riphah International University",{"id":166,"slug":167,"hasResults":11,"nctId":168,"briefTitle":169,"officialTitle":170,"acronym":4,"eligibilityCriteria":171,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":172,"enrollmentInfo":173,"targetDuration":4,"studyType":22,"phases":175,"briefSummary":176,"conditions":177,"keywords":182,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":187,"lastUpdatePostDateStruct":188,"startDateStruct":190,"completionDateStruct":192,"leadSponsor":194,"locationsCount":81},"100610918","effects-of-fun-core-child-friendly-core-stabilization-exercises-on-balance-and-functional-mobility-in-children-with-spastic-cerebral-palsy-100610918","NCT07233824","Effects of Fun-Core (Child-Friendly Core Stabilization) Exercises on Balance and Functional Mobility in Children With Spastic Cerebral Palsy","Effects of Fun-Core (Child-Friendly Core Stabilization) Exercises on Balance and Functional Mobility in Children With Spastic Cerebral Palsy: A Single-Blind Randomized Controlled Trial","Inclusion Criteria:\n\n* Children with hemiplegic cerebral palsy between the ages of 6 and 12\n* Children with Gross Motor Function Classification System (GMFCS) Levels 1, 2, and 3\n* Shoe sizes 30 and above\n\nExclusion Criteria:\n\n* Cognitive impairments that prevent understanding and performing simple commands and tasks\n* Botulinum toxin injections into the upper and\u002For lower extremities within the last 6 months\n* History of lower extremity or lumbar surgery within the last year\n* Presence of uncontrolled severe epileptic seizures\n* Presence of severe vision or hearing problems\n* Presence of fixed contractures in the lower extremities","12 Years",{"count":174,"type":21},54,[24],"A total of 54 children, aged between 6 and 12 years, diagnosed with hemiplegic cerebral palsy and not meeting the exclusion criteria, who registered at the outpatient clinics of the Department of Physical Medicine and Rehabilitation, Istanbul University, Istanbul Faculty of Medicine, between June 1, 2025 and March 1, 2026, were planned to be included in our thesis study, which was planned to be prospective, randomized and single-blind. Children and their parents will be informed verbally and in writing about the study's purpose, duration, and method of implementation, and their informed consent will be obtained. They will be asked to sign an \"Informed Consent Form.\" Patient assessment and follow-up forms will be completed at pre- and post-treatment follow-ups. Patients who meet the inclusion criteria will be numbered according to their order of admission and then randomly assigned to either the intervention or control groups by a computer program.\n\nIn addition to a brochure showing the number of sets and repetitions to be given to the patients as a standard home exercise program, the Fun-Core video exercise program, designed as a child-friendly core stabilization exercise program to be performed 3 times a week, will be given to the intervention group (G1), and the exercises will be delivered to the participants through a website with special accounts.\n\nThe control group (G2) will receive a standard home exercise program in brochure format, showing the number of sets and repetitions. The exercise program will be performed at home three times a week for 8 weeks.",[27,124,178,179,180,181],"Core Stabilization","Exercise","Functional Mobility","Balance",[183,65,184,185,186],"core stabilization exercises","functional mobility","balance","child friendly","2025-11-16",{"date":189,"type":36},"2025-11-18",{"date":191,"type":36},"2025-09-17",{"date":193,"type":21},"2026-05-31",{"name":195,"class":42},"Istanbul University",{"id":197,"slug":198,"hasResults":11,"nctId":199,"briefTitle":200,"officialTitle":201,"acronym":4,"eligibilityCriteria":202,"healthyVolunteers":11,"sex":16,"minAge":203,"maxAge":204,"enrollmentInfo":205,"targetDuration":4,"studyType":22,"phases":207,"briefSummary":208,"conditions":209,"keywords":210,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":213,"lastUpdatePostDateStruct":214,"startDateStruct":216,"completionDateStruct":218,"leadSponsor":220,"locationsCount":81},"100519213","implementation-of-therapy-together-100519213","NCT06040619","Implementation of Therapy Together","Implementation of Therapy Together With the State of Texas Early Childhood Intervention Program","Inclusion Criteria:\n\n* at risk for developing cerebral palsy or have been diagnosed with cerebral palsy\n* children ages 3 months to 5 years 11 months\n* present with asymmetric hand use\n* present with a unilateral upper limb impairment\n* able to visually attend to objects\n* demonstrate an interest in objects\n* attempt to reach for or grasp objects with the impaired upper extremity\n\nExclusion Criteria:\n\n* uncontrolled epilepsy\n* significant visual impairment\n* severe behavioral problems\n* inability to complete the assessment protocol.","3 Months","71 Months",{"count":206,"type":21},30,[24],"The goal of this clinical trial is to learn about the implementation of Therapy Together, a pediatric constraint-induced movement therapy program in young children with unilateral cerebral palsy. The main question\\[s\\] it aims to answer are:\n\n* Is the Therapy Together program effective in improving hand function and occupational performance compared to usual care?\n* Is it feasible to implement the Therapy Together program within the standard care, early intervention framework?\n\nParticipants will participate in an 8-week pediatric constraint-induced movement therapy program. Researchers will compare the group completing the Therapy Together Program to a group that is receiving usual care to see if there is a difference in the change in hand function, occupational performance, and development.",[96,27],[211,212],"constraint induced movement therapy","caregiver coaching","2025-09-04",{"date":215,"type":36},"2025-09-11",{"date":217,"type":36},"2023-11-13",{"date":219,"type":21},"2026-08",{"name":221,"class":42},"Texas Scottish Rite Hospital for Children",{"id":223,"slug":224,"hasResults":11,"nctId":225,"briefTitle":226,"officialTitle":227,"acronym":4,"eligibilityCriteria":228,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":229,"targetDuration":4,"studyType":22,"phases":230,"briefSummary":231,"conditions":232,"keywords":233,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":238,"lastUpdatePostDateStruct":239,"startDateStruct":241,"completionDateStruct":243,"leadSponsor":245,"locationsCount":4},"100598319","weight-bearing-exercises-with-nmes-on-balance-and-functional-abilities-in-children-with-hemiplegia-100598319","NCT07069946","Weight Bearing Exercises With NMES on Balance and Functional Abilities In Children With Hemiplegia","Effect of Weight Bearing Exercises With Neuromuscular Electrical Stimulation on Balance and Functional Abilities In Children With Hemiplegia","Inclusion Criteria:\n\n* Children diagnosed with hemiplegic cerebral palsy.\n* Their age will range from 6-10 years.\n* Both sexes will be included.\n* All participants will be able to follow simple commands.\n* They will be graded as mild spasticity of the lower limbs according to MAS grade 1 to 1+ .\n* They will be at levels I and II based on the GMFCS\n\nExclusion Criteria:\n\n* Children with any neurological conditions other than hemiplegic cerebral palsy will be excluded from the study.\n* Musculoskeletal problems or congenital deformity.\n* Children with fixed contracture.\n* Lower limb surgery in the last one year.\n* Rhizotomy, or injection of botulinum toxin into the lower limb muscles during the previous 6 months.\n* Receive any medications that affect the arousal and alertness status.\n* Children having epilepsy.\n* Visual or auditory defects.\n* Skin sensitivity.",{"count":206,"type":21},[24],"This study will be conducted to investigate the combining effect of weight-bearing exercises program with neuromuscular electrical stimulation on balance and functional abilities in children with hemiplegic cerebral palsy.",[27],[234,235,185,236,237],"weight-bearing exercises program","neuromuscular electrical stimulation","functional abilities","hemiplegic cerebral palsy","2025-07-08",{"date":240,"type":36},"2025-07-17",{"date":242,"type":21},"2025-07-15",{"date":244,"type":21},"2025-12-15",{"name":41,"class":42},{"id":247,"slug":248,"hasResults":11,"nctId":249,"briefTitle":250,"officialTitle":251,"acronym":4,"eligibilityCriteria":252,"healthyVolunteers":11,"sex":16,"minAge":253,"maxAge":90,"enrollmentInfo":254,"targetDuration":4,"studyType":22,"phases":256,"briefSummary":257,"conditions":258,"keywords":259,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":261,"lastUpdatePostDateStruct":262,"startDateStruct":264,"completionDateStruct":266,"leadSponsor":268,"locationsCount":81},"100519812","acceptability-and-efficacy-of-go-move-100519812","NCT06048419","Acceptability and Efficacy of GO MOVE","Acceptability and Efficacy of GO MOVE: A Mobile Health Technology for Youth With Unilateral Cerebral Palsy","Inclusion Criteria:\n\n* Inclusion criteria for participants to enroll in the study include a diagnosis of unilateral CP or a non-progressive brain lesion, injury, or trauma of the developing brain that presents with a unilateral upper limb motor impairment. GMFCS levels 1 or 2. MACS levels 1-3. Age 3-17 years old, ability to follow directions, ability to complete the assessment protocol, and the ability to access the GO MOVE webpage on a personal device. All ethnic\u002Fracial groups will be eligible to participate. The ability to participate in everyday activities without restriction from a physician throughout the duration of their participation in the study (does not have restrictions\u002Fcontraindications following a medical procedure).\n\nExclusion Criteria:\n\n* The study will exclude any patients with uncontrolled epilepsy or significant visual impairment. The study will exclude any patient with severe behavioral problems or the inability to complete the assessment protocol or home program.","3 Years",{"count":255,"type":21},50,[24],"The goal of this clinical trial is to learn about the acceptability and efficacy of Go Move, a mobile website developed to assist youth with unilateral cerebral palsy and their caregivers with setting goals and selecting exercises and activities to meet the goals. The main question\\[s\\] it aims to answer are:\n\n* Is Go Move accepted by youth with unilateral cerebral palsy and their caregivers?\n* Does Go Move support goal attainment for youth with unilateral cerebral palsy?\n\nParticipants will set up and participate in a goal-driven home program using the Go Move mobile website. Participants will spend 1 hour and 15 minutes per week for 6 weeks working on their home program and will complete pre-intervention and post-intervention assessments.",[96,27],[260],"home program","2025-03-06",{"date":263,"type":36},"2025-03-10",{"date":265,"type":36},"2024-02-20",{"date":267,"type":21},"2026-12",{"name":221,"class":42},{"id":270,"slug":271,"hasResults":11,"nctId":272,"briefTitle":273,"officialTitle":274,"acronym":4,"eligibilityCriteria":275,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":172,"enrollmentInfo":276,"targetDuration":4,"studyType":22,"phases":278,"briefSummary":279,"conditions":280,"keywords":281,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":287,"lastUpdatePostDateStruct":288,"startDateStruct":290,"completionDateStruct":292,"leadSponsor":294,"locationsCount":81},"100581121","modified-constraint-induced-movement-therapy-versus-virtual-reality-training-in-children-with-cerebral-palsy-100581121","NCT06846190","Modified Constraint Induced Movement Therapy Versus Virtual Reality Training in Children With Cerebral Palsy","Effects of Modified Constraint Induced Movement Therapy Versus Virtual Reality Training in Children With Hemiplegic Cerebral Palsy","Inclusion Criteria:\n\n* Age range between 5 to 16 years of age.\n* Medical diagnosis of spastic hemiparetic CP.\n* At least 20◦wrist and 10◦ active finger extension from full flexion.\n* More movement deficits in 1 upper extremity (less than 2.5 on the Amount of Use scale (AOU) on the Pediatric Motor Activity Log (PMAL)).\n* Muscle tone less than 3 on the Modified Ashworth Scale.\n* Normal or corrected-to-normal vision and hearing.\n* Classified level I, II, or III of the Manual Ability Classification System ( MACS) for Children with CP\n\nExclusion Criteria:\n\n* Health problems not associated with CP.\n* Seizure hemispatial neglect.\n* Orthopaedic surgery on the involved upper extremity.\n* Botulinum toxin therapy for the affected upper extremity within the past 6 months or within the study period.\n* Balance problems",{"count":277,"type":21},20,[24],"Children with hemiplegic cerebral palsy (CP) are characterized by motor impairments mainly lateralized to one side of the body, with greater upper limb than lower limb involvement; these impairments may further limit the daily activities and school participation of children with hemiplegic CP. For the improvement of activity limitations in hemipelagic cerebral palsy children will take 20 hemiplegic cerebral palsy children with the age of 5-16 year all participants will be randomly assign and use modified Constraint induced movement therapy and virtual reality techniques.\n\nmCIMT and Hot pack will be given to group I and unaffected hand will immobilized by a volar resting splint extending from finger tips to the proximal forearm. Use splint every day for at least 5 waking hours individualized, 18-hour program of mCIMT every other day, 3 times per week during a 4-week period. Each modified CIMT session continued for 1.5 hours will give to group I on the other hand VR and Hot pack will give to group II and 18-hour VR program, every other day, 3 times per week for 4 weeks will give Each VR session continued for 1.5 hours. Then evaluate both groups on follow up.\n\nAll the data will be collected from Rising Sun Institute by using ABILHAND-KIDS questionnaire and Children's hand-use experience questionnaire. The reliability and validity of tools and mentioned.\n\nThe duration of study will be 6-months. Data will be analyzed with the help of SPSS 27",[27],[282,283,284,285,286],"Cerebral palsy","Hemiplegic","Modified constraint induced movement therapy","Spastic","Virtual reality","2025-02-24",{"date":289,"type":36},"2025-02-25",{"date":291,"type":36},"2025-02-15",{"date":293,"type":21},"2025-07-31",{"name":164,"class":42},{"id":296,"slug":297,"hasResults":11,"nctId":298,"briefTitle":299,"officialTitle":300,"acronym":4,"eligibilityCriteria":301,"healthyVolunteers":11,"sex":16,"minAge":302,"maxAge":18,"enrollmentInfo":303,"targetDuration":4,"studyType":22,"phases":305,"briefSummary":306,"conditions":307,"keywords":308,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":313,"lastUpdatePostDateStruct":314,"startDateStruct":316,"completionDateStruct":318,"leadSponsor":320,"locationsCount":81},"100572069","virtual-reality-with-mirror-therapy-on-upper-limb-function-100572069","NCT06728475","Virtual Reality With Mirror Therapy on Upper Limb Function","Effect Of Virtual Reality With Mirror Therapy on Upper Limb Functions in Children With Hemiplegic Cerebral Palsy","Inclusion Criteria:\n\n* Children will be included in the study if they fulfil the following criteria:\n\n  1. A medical diagnosis of spastic hemiplegic CP made by pediatric neurologists.\n  2. Children with spasticity grades ranged from 1 to 1+ according to MAS.\n  3. Their age range from 4 to 10 years.\n  4. Children level 1 and level 2 in gross motor functional classification (GMFC 1\\&2)\n\nExclusion Criteria:\n\n* Children will be excluded from the study if:\n\n  1. They had a permanent deformity (bony or soft tissue contractures).\n  2. Children having visual or auditory defects.\n  3. Children who can not understand verbal commands\n  4. Children who had Botox application to the upper extremity in the past 6 months or had undergone a previous surgical intervention to wrist and hand.","4 Years",{"count":304,"type":21},60,[24],"The goal of this clinical trial is to address the effect of (Virtual Reality) and (Mirror Therapy) together on upper limb function in hemiplegic Cerebral Palsy children , male or female ranged between 3 to 10 years of age\n\n. The main question of the study is Are there any significant differences between the effects of virtual reality , mirror therapy and the combined effect of both techniques and on upper limb function in hemiplegic CP children?\n\nParticipants will be subdevided into three groups A , B ,C Group (A): will receive VR in addition to designed physical therapy program Group (B): will receive MT in addition to designed physical therapy program Group (C): will receive the compound effect of both techniques in addition to designed physical therapy program",[27],[309,310,286,311,312],"Hemiplagia","Upper limb function","Mirror therapy","Xbox 360","2024-12-06",{"date":315,"type":36},"2024-12-11",{"date":317,"type":21},"2024-12-10",{"date":319,"type":21},"2025-03-15",{"name":321,"class":42},"Kafrelsheikh University",{"id":323,"slug":324,"hasResults":11,"nctId":325,"briefTitle":326,"officialTitle":327,"acronym":328,"eligibilityCriteria":329,"healthyVolunteers":11,"sex":16,"minAge":330,"maxAge":331,"enrollmentInfo":332,"targetDuration":4,"studyType":22,"phases":333,"briefSummary":334,"conditions":335,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":336,"lastUpdatePostDateStruct":337,"startDateStruct":339,"completionDateStruct":341,"leadSponsor":343,"locationsCount":81},"100570256","constraint-induced-movement-therapy-versus-cross-education-in-children-with-cerebral-palsy-100570256","NCT06704880","CONSTRAINT-INDUCED MOVEMENT THERAPY VERSUS CROSS EDUCATION IN CHILDREN WITH CEREBRAL PALSY","Lower Limb Constraint-induced Movement Training Versus Strength Training of the Non-hemiplegic Lower Limb on Motor Performance in Children With Hemiplegic Cerebral Palsy: A Randomized Control Trial.","NEUROLOGY","Inclusion Criteria:\n\n1. Children with hemiplegic cerebral palsy aged age between 4 and 10.\n2. (GMFCS) levels I, II and III.\n3. Able to follow therapist instructions during training session.\n\nExclusion Criteria:\n\n1. Lack of patient's cooperation.\n2. Difficulty wearing constraint method due to severe joint deformation or\u002Fand contracture.\n3. Patients were treated with botulinum toxin during the last 3 months.\n4. Seizure disorder not fully controlled by medication.","5 Years","15 Years",{"count":20,"type":21},[24],"This clinical trial aims to Compare the effectiveness of lower limb CIMT and the Strength Training of the Non-Hemiplegic lower limb on motor performance in hemiplegic children with CP.\n\nParticipants will:\n\ndiagnosed with hemiplegic cerebral palsy treated with CIMT or Strength training (cross-education) for a non-hemiplegic limb for 8 weeks.\n\n3 sessions per week. Measurements will be taken at baseline and then at the end of the 8 weeks.",[27],"2024-11-25",{"date":338,"type":36},"2024-11-26",{"date":340,"type":21},"2024-11-30",{"date":342,"type":21},"2025-04-29",{"name":344,"class":42},"Imam Abdulrahman Bin Faisal University",{"id":346,"slug":347,"hasResults":11,"nctId":348,"briefTitle":349,"officialTitle":349,"acronym":4,"eligibilityCriteria":350,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":52,"enrollmentInfo":351,"targetDuration":4,"studyType":22,"phases":353,"briefSummary":354,"conditions":355,"keywords":359,"overallStatus":71,"whyStopped":4,"lastUpdateSubmitDate":366,"lastUpdatePostDateStruct":367,"startDateStruct":369,"completionDateStruct":371,"leadSponsor":373,"locationsCount":81},"100316689","tdcs-and-bimanual-therapy-for-children-with-hemiplegic-cerebral-palsy-100316689","NCT03402854","tDCS and Bimanual Therapy for Children With Hemiplegic Cerebral Palsy","Inclusion Criteria:\n\n* Diagnosis of congenital hemiplegic cerebral palsy\n* Ability to lift and grasp light objects with affected hand\n* Ability to extend wrist of affected hand 15 degrees\n* Ability to follow instructions and provide informed assent\n* Parent(s) able to provide informed consent\n\nExclusion Criteria:\n\n* Seizures after age 2 years\n* Spasticity medication within 6 months before study\n* Selective dorsal rhizotomy\n* Surgery in affected upper extremity within year before study",{"count":352,"type":21},80,[24],"The goal of this study is to test the efficacy of transcranial direct current stimulation combined with bimanual training on hand function in children with unilateral spastic cerebral palsy (USCP). Children who enroll in the protocol will be randomized to receive either sham (not stimulating) tDCS plus bimanual training, or active (stimulating) tDCS plus bimanual training.",[96,27,356,357,358],"Spastic Hemiplegic Cerebral Palsy","Spastic Hemiparesis","Spastic Hemiplegia",[360,361,362,363,364,365],"pediatric","children","non-invasive brain stimulation","transcranial direct current stimulation","bimanual training","hand training","2024-07-15",{"date":368,"type":36},"2024-07-16",{"date":370,"type":36},"2019-12-01",{"date":372,"type":21},"2025-08-31",{"name":374,"class":42},"Burke Medical Research Institute"]