[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"hemodynamic-effects-of-general-anesthesia\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:hemodynamic-effects-of-general-anesthesia":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":29,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":5},"100615548","incidence-and-risk-factors-of-post-induction-hypotension-in-geriatric-cancer-patients-100615548",false,"NCT07294040","Incidence and Risk Factors of Post-Induction Hypotension in Geriatric Cancer Patients","A Prospective Observational Study to Determine the Incidence and Risk Factors of Post-Induction Hypotension in Geriatric Oncologic Patients Undergoing General Anesthesia at a Tertiary Oncology Center","Inclusion Criteria:\n\n* Adults ≥65 years of age\n\nPatients with a diagnosis of cancer and scheduled for surgery\n\nAbility and willingness to provide written informed consent\n\nASA physical status class II-IV\n\nExclusion Criteria:\n\nPatients under 65 years of age\n\nPatients without a confirmed oncologic diagnosis\n\nRefusal to provide written informed consent\n\nPatients undergoing regional anesthesia\n\nPatients with tracheostomy or requiring multiple intubation attempts\n\nHistory of peripheral arterial disease\n\nUse of vasopressors before the start of surgery\n\nUncontrolled hypertension (blood pressure \\>180\u002F110 mmHg)\n\nAdvanced heart failure (Ejection Fraction \\\u003C40%)\n\nSevere arrhythmias such as atrial fibrillation or significant ventricular arrhythmias that preclude reliable hemodynamic monitoring","ALL","65 Years",{"count":19,"type":20},140,"ESTIMATED","OBSERVATIONAL","This observational clinical study aims to investigate the incidence and risk factors of post-induction hypotension (PIH) in geriatric cancer patients undergoing surgery under general anesthesia. PIH is defined as a drop in mean arterial pressure of ≥30% from baseline or below 65 mmHg within the first 20 minutes after anesthesia induction, prior to surgical stimulation.\n\nThe primary objective is to determine the frequency of PIH in elderly oncology patients. Secondary objectives include evaluating the association of PIH with age, ASA score, cancer type, oncological treatments (chemotherapy\u002Fradiotherapy), comorbidities, medication use, anemia, biochemical parameters, and preoperative perfusion index (PI) and pleth variability index (PVI).\n\nFindings from this study are expected to contribute to improved perioperative management and to the development of tailored anesthesia protocols for geriatric oncology patients.",[24,25,26,27,28],"Post-induction Hypotension (PIH)","Geriatric Patient","Oncologic Disease","Hemodynamic Effects of General Anesthesia","Risk Factors Associated With Anesthesia-Induced Hypotension",[30,31,32,33,34,35,36],"Post-induction Hypotension","Perfusion Index (PI)","Pleth Variability Index (PVI)","geriatric patient","Oncologic Patients","General Anesthesia","Hemodynamics","RECRUITING","2025-12-07",{"date":40,"type":41},"2025-12-19","ACTUAL",{"date":43,"type":41},"2025-05-25",{"date":45,"type":20},"2026-05-25",{"name":47,"class":48},"Dolunay ARIK","OTHER"]