[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"hemodynamic-response\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:hemodynamic-response":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":26,"conditions":27,"keywords":31,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":5},"100587969","phase-2-oral-melatonin-vs-nebulized-dexmedetomidine-premedication-on-attenuation-of-hemodynamic-response-to-direct-laryngoscopy-and-tracheal-intubation-in-hypertensive-patients-100587969",false,"NCT06935292","Oral Melatonin VS Nebulized Dexmedetomidine Premedication on Attenuation of Hemodynamic Response to Direct Laryngoscopy and Tracheal Intubation in Hypertensive Patients","Comparative Study Between Oral Melatonin and Nebulized Dexmedetomidine Premedication on Attenuation of Hemodynamic Response to Direct Laryngoscopy and Tracheal Intubation in Hypertensive Patients: A Prospective Randomized Trial","Inclusion Criteria:\n\n* Age (40-60) years of both genders.\n* Controlled hypertensive patients.\n* Categorized as ASA physical status II.\n* Planning to do an elective surgery under General Anesthesia.\n\nExclusion Criteria:\n\n* Patient refusal to participate in the study.\n* Patient with expected difficult intubation.\n* Body Mass Index (BMI) \\> 30 kg\u002Fm2.\n* History of allergy to the drugs of the study.\n* Patients with Heart rate\\\u003C50 or Heart block.\n* End stage renal and hepatic disease.\n* Patients on beta blocker, oral hypoglycemics, anti-depressants, anti-convulsants, anti- psychotics and thyroid medications.\n* Pregnant or lactating females.","ALL","40 Years","60 Years",{"count":20,"type":21},70,"ESTIMATED","INTERVENTIONAL",[24,25],"PHASE2","PHASE3","The aim of this study is to compare the efficacy of oral melatonin versus nebulized dexmedetomidine in attenuating the hemodynamic response to direct laryngoscopy and endotracheal intubation in controlled hypertensive patients prepared for general anesthesia",[28,29,30],"Tracheal Intubation Morbidity","Laryngoscopy","Hemodynamic Response",[32,33,34,35,36,37],"Direct laryngoscope","Dexmedetomidine","Melatonin","Tracheal Intubation","Hypertension","Hemodynamic response","NOT_YET_RECRUITING","2025-04-11",{"date":41,"type":42},"2025-04-20","ACTUAL",{"date":44,"type":21},"2025-04",{"date":46,"type":21},"2026-04",{"name":48,"class":49},"Tanta University","OTHER"]