[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"hemodynamic-stability\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:hemodynamic-stability":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,6,0,[8,47,84,111,133,165],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100644754","remimazolam-on-the-incidence-of-postoperative-acute-kidney-injury-100644754",false,"NCT07674719","Remimazolam on the Incidence of Postoperative Acute Kidney Injury","The Effect of Intraoperative Remimazolam Administration on the Incidence of Postoperative Acute Kidney Injury After Hepatobiliary and Pancreatic Surgery : a Prospective Randomized Controlled Trial","Inclusion Criteria:\n\n* Ages 19 or older and under 85\n* Patients scheduled to undergo elective hepatopancreatic surgery under general anesthesia\n* American Society of Anesthesiologists (ASA) physical grade 1-3\n* Those who voluntarily consented to a written informed consent form prior to participation in the study\n\nExclusion Criteria:\n\n* Patients with hypersensitivity to other benzodiazepine drugs, including remimazolam, and to the components of this drug (e.g., patients with severe hypersensitivity to dextran 40)\n* Patients with hypersensitivity to propofol\n* Patients with underlying conditions: liver, neurological disorders, or acute narrow-angle glaucoma\n* Patients with severe or acute respiratory failure\n* Patients in shock or a coma\n* Patients taking TCA antidepressants\n* Patients with preoperative chronic kidney disease","ALL","19 Years","85 Years",{"count":20,"type":21},78,"ESTIMATED","INTERVENTIONAL",[24],"NA","We hypothesized that in patients undergoing elective hepatobiliary-pancreatic surgery, the group in which anesthesia is induced and maintained with remimazolam during surgery would maintain hemodynamic stability and reduce the incidence of postoperative acute kidney injury compared to propofol. The purpose is to provide practical evidence for perioperative management differentiated from other surgeries for hepatobiliary-pancreatic surgery patients for whom intraoperative fluid therapy is restricted.",[27,28,29,30,31,32,33],"Remimazolam","Propofol","Acute Kidney Injury","Hemodynamic Stability","Hepatobiliary Surgery","Fluid Therapy","Fluid Therapy DURING SURGERY","NOT_YET_RECRUITING","2026-06-24",{"date":37,"type":38},"2026-06-29","ACTUAL",{"date":40,"type":21},"2026-06-26",{"date":42,"type":21},"2028-06-26",{"name":44,"class":45},"Seoul National University Bundang Hospital","OTHER",1,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":53,"eligibilityCriteria":54,"healthyVolunteers":11,"sex":55,"minAge":4,"maxAge":56,"enrollmentInfo":57,"targetDuration":4,"studyType":22,"phases":59,"briefSummary":60,"conditions":61,"keywords":64,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":83},"100612247","hemodynamic-effects-of-remimazolam-vs-propofol-during-robot-assisted-gynecologic-surgery-100612247","NCT07251101","Hemodynamic Effects of Remimazolam vs Propofol During Robot-assisted Gynecologic Surgery","A Randomized, Parallel, Open-label With Blinded Assessment Study Comparing Hemodynamic Profiles Between Remimazolam- and Propofol-based Total Intravenous Anesthesia in Patients Undergoing Robot-assisted Gynecologic Surgery","By_HD","Inclusion Criteria:\n\n* Female patients \\\u003C65 years of age\n* American Society of Anesthesiologists (ASA) physical status I-II\n* Scheduled to undergo robotic hysterectomy under general anesthesia\n\nExclusion Criteria:\n\n* Body mass index (BMI) \\> 35 kg\u002Fm²\n* Baseline hypotension (systolic blood pressure \\\u003C100 mmHg) or bradycardia (heart rate \\\u003C60 bpm)\n* History of ischemic heart disease or cardiac conduction block\n* Significant cardiopulmonary disease, including hypoxemia (SpO₂ \\\u003C90%), uncontrolled asthma, or chronic obstructive pulmonary disease (COPD)\n* Use of inhalational anesthetics during anesthesia\n* Conversion from robotic\u002Flaparoscopic surgery to open laparotomy","FEMALE","65 Years",{"count":58,"type":21},58,[24],"This single-center study at CHA Ilsan Medical Center compares intraoperative hemodynamics between remimazolam- and propofol-based total intravenous anesthesia (TIVA) in patients undergoing robot-assisted gynecologic surgery requiring pneumoperitoneum and steep Trendelenburg positioning.",[62,30,63],"Anesthesia, Intravenous","Gynecologic Surgery",[65,66,67,68,69,70,71,72,73],"remimazolam","propofol","hemodynamics","laparoscopic surgery","general anesthesia","Trendelenburg position","pneumoperitoneum","gynecologic surgery","total intravenous anesthesia (TIVA)","2026-03-23",{"date":76,"type":38},"2026-03-27",{"date":78,"type":21},"2026-05-02",{"date":80,"type":21},"2027-12-30",{"name":82,"class":45},"Ilsan Cha hospital",2,{"id":85,"slug":86,"hasResults":11,"nctId":87,"briefTitle":88,"officialTitle":89,"acronym":90,"eligibilityCriteria":91,"healthyVolunteers":11,"sex":16,"minAge":92,"maxAge":4,"enrollmentInfo":93,"targetDuration":4,"studyType":22,"phases":95,"briefSummary":96,"conditions":97,"keywords":4,"overallStatus":101,"whyStopped":4,"lastUpdateSubmitDate":102,"lastUpdatePostDateStruct":103,"startDateStruct":105,"completionDateStruct":107,"leadSponsor":109,"locationsCount":46},"100621032","frequency-of-electrical-acupoint-stimulation-on-hypotension-in-tavr-patients-100621032","NCT07365345","Frequency of Electrical Acupoint Stimulation on Hypotension in TAVR Patients","The Influence of Electrical Acupoint Stimulation at Different Frequencies on Hemodynamics During Anesthesia Induction in Patients Undergoing TAVR Surgery","FRESH-T","Inclusion Criteria:\n\n* The age of the patients is 60 years or older;\n* Patients who are scheduled to undergo TAVR surgery under general anesthesia;\n\nExclusion Criteria:\n\n* Body mass index less than 18 kg\u002Fm2 or greater than 30 kg\u002Fm2;\n* Hemodynamic instability (severe arrhythmia, decompensated heart failure);\n* Hypotension after admission requiring intervention with vasoactive drugs;\n* Severe liver or kidney dysfunction;\n* Those who are contraindicated for electrical stimulation, including those with local skin damage, infection, or having implanted electrophysiological devices in the body.","60 Years",{"count":94,"type":21},150,[24],"Within 30 minutes before anesthesia, acupoint electrical stimulation at different frequencies were applied at Neiguan, Jian Shi, and Baihui. The changes in blood pressure during the anesthesia induction period were compared between the high-frequency group and the low-frequency group.",[98,30,99,100],"Transcatheter Aortic Valve Replacement (TAVR)","Anesthesia Induction","Electro-acupuncture","RECRUITING","2026-03-22",{"date":104,"type":38},"2026-03-25",{"date":106,"type":38},"2026-01-30",{"date":108,"type":21},"2026-12-31",{"name":110,"class":45},"Air Force Military Medical University, China",{"id":112,"slug":113,"hasResults":11,"nctId":114,"briefTitle":115,"officialTitle":116,"acronym":117,"eligibilityCriteria":118,"healthyVolunteers":11,"sex":16,"minAge":119,"maxAge":4,"enrollmentInfo":120,"targetDuration":4,"studyType":22,"phases":122,"briefSummary":123,"conditions":124,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":126,"lastUpdatePostDateStruct":127,"startDateStruct":129,"completionDateStruct":131,"leadSponsor":132,"locationsCount":4},"100618287","crystalloid-vs-colloid-for-hemodynamics-during-anesthesia-induction-in-tavr-patients-100618287","NCT07329660","Crystalloid vs Colloid for Hemodynamics During Anesthesia Induction in TAVR Patients","The Impact of Different Preload Strategies on Hemodynamics During Anesthesia Induction in TAVR Patients","CHAIN-T","Inclusion Criteria:\n\n* Age ≥ 18 years;\n* Patients scheduled to undergo elective TAVR under general anesthesia;\n\nExclusion Criteria:\n\n* Allergy to hydroxyethyl starch, its components, and\u002For sodium lactate Ringer's solution, or a history of colloidal allergy;\n* Severe cardiac dysfunction (ejection fraction\\[EF\\] \\\u003C 35%);\n* Severe renal dysfunction (creatinine \\> 132 μg\u002FL and\u002For requiring renal replacement therapy);\n* Morbid obesity (body mass index\\[BMI\\] \\> 37.5 kg\u002Fm² or \\> 32.5 kg\u002Fm² with metabolic diseases);\n* Severe hepatic dysfunction ;\n* Severe electrolyte disturbances ;\n* Patients with preoperative intracranial hypertension requiring dehydration therapy;\n* Expected postoperative hospital stay \\\u003C 24 hours;\n* Patients scheduled for multiple surgeries during this hospitalization.","18 Years",{"count":121,"type":21},116,[24],"The purpose of this study is to evaluate whether the administration of 5 ml\u002Fkg of colloid solution prior to anesthesia induction, compared with 5 ml\u002Fkg of lactated Ringer's solution, can reduce hemodynamic fluctuations during the induction period (defined as the first 15 minutes after induction) in patients undergoing Transcatheter Aortic Valve Replacement (TAVR).",[125,30,99],"Transcatheter Aortic Valve Replacement","2026-02-25",{"date":128,"type":38},"2026-02-27",{"date":130,"type":21},"2026-02-16",{"date":108,"type":21},{"name":110,"class":45},{"id":134,"slug":135,"hasResults":11,"nctId":136,"briefTitle":137,"officialTitle":138,"acronym":4,"eligibilityCriteria":139,"healthyVolunteers":11,"sex":16,"minAge":119,"maxAge":140,"enrollmentInfo":141,"targetDuration":4,"studyType":22,"phases":143,"briefSummary":144,"conditions":145,"keywords":151,"overallStatus":101,"whyStopped":4,"lastUpdateSubmitDate":155,"lastUpdatePostDateStruct":156,"startDateStruct":158,"completionDateStruct":160,"leadSponsor":162,"locationsCount":46},"100603619","hemodynamic-effects-of-surgical-position-in-prone-vs-supine-percutaneous-nephrolithotomy-100603619","NCT07138872","Hemodynamic Effects of Surgical Position in Prone vs. Supine Percutaneous Nephrolithotomy","The Effect of Surgical Position on Hemodynamics in Percutaneous Nephrolithotomy Performed in Prone and Supine Positions","Inclusion Criteria:\n\n* ASA physical status I-III\n* Presence of renal calculi indicated for PNL\n\nExclusion Criteria:\n\n* Pregnancy\n* Uncontrolled coagulopathy\n* Previous renal surgery\n* Severe cardiac, pulmonary, or neurological disease\n* Preoperative urinary tract infection (non-sterile urine culture)\n* Surgery duration \\\u003C60 minutes or \\>120 minutes\n* Preoperative blood transfusion\n* Multiple access tracts","80 Years",{"count":142,"type":21},84,[24],"This prospective, randomized controlled study evaluates the hemodynamic effects of prone and supine positions during percutaneous nephrolithotomy (PNL) for large kidney stones. Surgical position may influence intraoperative and postoperative hemodynamic stability. Prone positioning can increase intrathoracic pressure and reduce venous return, whereas supine positioning may provide greater hemodynamic stability. A total of 84 patients will be randomized to undergo PNL in prone or supine positions. Primary outcomes include changes in hemodynamic parameters during surgery. Results may guide surgical position selection, especially in patients with potential hemodynamic risk.",[146,147,148,149,30,150],"Percutaneous Nephrolithotomy (PCNL)","Surgical Positioning","Prone Position","Supine Position","Nephrolithiasis",[152,148,153,149,154,150],"PCNL","Percutaneous Nephrolithotomy","Hemodynamic stability","2025-08-16",{"date":157,"type":38},"2025-08-24",{"date":159,"type":38},"2025-06-01",{"date":161,"type":21},"2025-12-30",{"name":163,"class":164},"Gaziosmanpasa Research and Education Hospital","OTHER_GOV",{"id":166,"slug":167,"hasResults":11,"nctId":168,"briefTitle":169,"officialTitle":170,"acronym":171,"eligibilityCriteria":172,"healthyVolunteers":11,"sex":16,"minAge":119,"maxAge":18,"enrollmentInfo":173,"targetDuration":4,"studyType":22,"phases":175,"briefSummary":176,"conditions":177,"keywords":180,"overallStatus":101,"whyStopped":4,"lastUpdateSubmitDate":186,"lastUpdatePostDateStruct":187,"startDateStruct":189,"completionDateStruct":191,"leadSponsor":193,"locationsCount":83},"100535429","fluid-removal-guided-by-vexus-score-with-usual-care-in-patients-with-acute-kidney-injury-after-cardiac-surgery-100535429","NCT06251713","Fluid-removal Guided by VeXUS Score With Usual Care in Patients With Acute Kidney Injury After Cardiac Surgery","Feasibility of a Randomised Trial Comparing a Fluid-removal Guided by VeXUS Score With Usual Care in Patients With Acute Kidney Injury After Cardiac Surgery: a Pilot Randomised Trial.","VeXUS","Inclusion Criteria:\n\n* Intensive care unit admission within 72 hours of cardiac surgery with extracorporeal circulation\n* Acute kidney injury defined by KDIGO criteria\n* Vasoactive inotropic score \\\u003C45 and capillary refill time \\\u003C3s\n* Informed written consent\n\nExclusion Criteria:\n\n* Hypokalaemia \\\u003C3.5mmol\u002FL\n* Hyponatremia\\\u003C125mmol\u002FL\n* Hypernatremia \\>145mmol\u002FL\n* Metabolic alkalosis with pH \\>7.50\n* Impossibility to measure capillary refill time\n* Chronic liver disease\n* Cirrhosis with portal hypertension\n* Known thrombus of the inferior vena cava\n* Mechanical circulatory assistance (ECMO or mono left ventricular assistance)\n* Severe pre-operative chronic kidney disease (GFR \\\u003C 30mL\u002Fmin\u002F1.73m2)\n* Need for renal replacement therapy anticipated by the attending physician within 24 hours\n* Known hypersensitivity to Furosemide and\u002For hydrochlorothiazide\n* Severe allergy to wheat\n* Patient already included in another interventional study with an exclusion period still in progress\n* Pregnant, breast-feeding or women of childbearing age without suitable contraception\n* Patients under guardianship, curatorship or safeguard of justice\n* Patients under psychiatric care\n* Patients not affiliated to a social security scheme or beneficiaries of a similar scheme",{"count":174,"type":21},40,[24],"Acute kidney injury affects more than 30% of patients after cardiac surgery, and is associated with an excess in mortality. There is a clinical continuum between acute kidney injury (transient if \\\u003C48h, persistent if \\>48h), the development of acute kidney and chronic renal failure. Each of these entities characterising renal recovery is associated with an increase in long-term morbidity and mortality. Fluid management in patients with acute kidney injury is challenging, as both hypovolaemia and hypervolaemia are detrimental. Venous congestion (reflecting intravascular hypervolaemia), is a well-established haemodynamic factor contributing to acute kidney injury after cardiac surgery. An ultrasound score, based on the venous doppler pattern explored in intra-abdominal organs, has recently been developed and is a better predictor of acute kidney injury than central venous pressure. Whether using the VeXUS score to guide fluid removal in haemodynamically stabilised patients could promote renal recovery after acute kidney injury remains to be investigated.\n\nBefore designing a large randomised trial to test such a strategy, its feasibility in a pilot randomised trial is assessed.",[29,178,179,30],"Cardiac Surgery","Venous Congestion",[181,182,179,183,184,185],"Acute kidney injury","Cardiac surgery","VeXUS score","diuretic","fluid removal","2025-04-09",{"date":188,"type":38},"2025-04-13",{"date":190,"type":38},"2024-07-31",{"date":192,"type":21},"2026-07",{"name":194,"class":45},"Hospices Civils de Lyon"]