[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"hemorrhoid-bleeding\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:hemorrhoid-bleeding":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,50,82,112],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":26,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":4},"100613271","bleeding-reduction-in-grade-ii-iii-haemorrhoids-through-embolization-treatment-100613271",false,"NCT07264413","Bleeding Reduction in Grade II-III Haemorrhoids Through Embolization Treatment","BRIGHT","Inclusion Criteria:\n\n1. Adult patients presenting bleeding Grade II-III haemorrhoids with French bleeding score ≥3 planned to be treated with HAE using embolization coils;\n2. Patients competent and willing to give written informed consent.\n\nExclusion Criteria:\n\n1. Minors and other vulnerable populations who may not be able to give informed consent freely or for whom participation is not essential to the study (incapacitated and unconscious individuals, persons deprived of liberty, pregnant and breastfeeding women, etc.);\n2. Patients receiving HAE using a combination of coils and particles, particles only, or any other embolic agents;\n3. Patients who have had previous surgical haemorrhoidectomy at any time or other treatments for haemorrhoids within 1 year before the planned HAE;\n4. Patients with known perianal sepsis, inflammatory bowel disease, peri-anal fistula, colorectal malignancy or pre-existing sphincter injury resulting in incontinence;\n5. Patients with an immunodeficiency;\n6. Known severe atheromatous disease with occlusion of target vessels preventing embolization;\n7. Absolute contraindication to contrast media;\n8. ECOG performance status \\> 2;\n9. Life expectancy \\\u003C 12 months;\n10. Patients with unstable angina;\n11. Patients currently taking nicorandil.","ALL","18 Years",{"count":19,"type":20},250,"ESTIMATED","OBSERVATIONAL","BRIGHT is a Europe-wide study that will follow up to 250 adults with bleeding symptoms from haemmorhoids (Grade II-III categories). It aims to understand how well a minimally invasive procedure called haemorrhoid artery embolization (HAE) works in everyday clinical practice, which is a technique that blocks the blood vessels feeding the haemorrhoids. As this technique does not require major surgery, HAE offers several benefits such as less trauma, quicker recovery, and the use of only local anaesthesia.",[24,25],"Hemorrhoid","Hemorrhoid Bleeding",[27,28,29,30,31,32,33,34,35,36,37],"Haemorrhoids","Grade II-III haemorrhoids","Symptomatic haemorrhoids","Hemorrhoidal bleeding","Haemorrhoidal disease","Haemorrhoid artery embolization","HAE","Artery embolization","Transarterial embolization","Minimally invasive","Embolization coils","NOT_YET_RECRUITING","2026-07-01",{"date":41,"type":42},"2026-07-02","ACTUAL",{"date":44,"type":20},"2026-08",{"date":46,"type":20},"2030-12",{"name":48,"class":49},"Cardiovascular and Interventional Radiological Society of Europe","OTHER",{"id":51,"slug":52,"hasResults":11,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":56,"eligibilityCriteria":57,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":58,"targetDuration":60,"studyType":21,"phases":4,"briefSummary":61,"conditions":62,"keywords":66,"overallStatus":70,"whyStopped":4,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":81},"100643064","prospective-hemorrhoidal-embolisation-piles-registry-100643064","NCT07635784","Prospective HemorrhoIdaL EmboliSation (PILES) Registry","Creation Of a Prospective Registry For Hemorrhoid Artery Embolization At The Joint & Vascular Institute","PILES","Inclusion Criteria:\n\n* Adults (≥18 years) with symptomatic bleeding internal hemorrhoids refractory to medical therapy, referred for HAE.\n\nExclusion Criteria:\n\n* Pregnancy, coagulopathy, severe comorbidities, or inability to consent.",{"count":59,"type":20},1200,"5 Years","The goal of this observational study (prospective registry) is to collect long-term real-world data on the effectiveness and safety of hemorrhoid artery embolization (HAE) for symptomatic bleeding internal hemorrhoids in adults aged 18 years or older that have not responded to medical therapy.\n\nThe main question it aims to answer are:\n\n1\\) Does HAE lead to sustained improvement in bleeding (HDSS scores over 12-36 months?\n\nParticipants will:\n\n* Undergo HAE as part of their routine clinical care.\n* Complete clinical follow-up assessments at 1, 3, 6, 12, 18, 24, and 36 months after treatment, including symptom and quality-of-life questionnaires.\n* Have safety outcomes tracked according to Society of Interventional Radiology guidelines.\n\nThere is no comparison group; results will be analyzed to identify predictors of success and inform best practices for patient selection and treatment.",[24,63,25,64,65],"Internal Hemorrhoids","Hemorrhoidal Bleeding","Internal Hemorrhoid",[67,68,69],"bleeding","hemorrhoids","internal hemorrhoids","RECRUITING","2026-06-10",{"date":73,"type":42},"2026-06-12",{"date":75,"type":42},"2026-01-18",{"date":77,"type":20},"2032-01",{"name":79,"class":80},"Joint & Vascular Institute","INDUSTRY",1,{"id":83,"slug":84,"hasResults":11,"nctId":85,"briefTitle":86,"officialTitle":87,"acronym":88,"eligibilityCriteria":89,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":90,"enrollmentInfo":91,"targetDuration":93,"studyType":21,"phases":4,"briefSummary":94,"conditions":95,"keywords":99,"overallStatus":70,"whyStopped":4,"lastUpdateSubmitDate":103,"lastUpdatePostDateStruct":104,"startDateStruct":106,"completionDateStruct":108,"leadSponsor":110,"locationsCount":81},"100615690","topical-nifedipine-03-plus-lidocaine-15-for-uncomplicated-hemorrhoidal-disease-100615690","NCT07295886","Topical Nifedipine 0.3% Plus Lidocaine 1.5% for Uncomplicated Hemorrhoidal Disease","Observational Study on the Use of Topical Nifedipine 0.3% and Lidocaine 1.5% in Acute Uncomplicated Hemorrhoidal Disease","NILOS","Inclusion Criteria:\n\n* Male and female patients aged 18-75 years.\n* Clinical or anoscopic diagnosis of acute hemorrhoidal disease with prolapse severity between Grade II and IV (Goligher), possibly associated with external congestion.\n* Patients who started treatment with nifedipine 0.3% + lidocaine 1.5% within the past 5 days.\n* Availability of clinical evaluations at treatment initiation (proctologic visit and HDSS, SHS-HD, VAS scales).\n* Ability to understand the informed consent.\n* Signed informed consent.\n\nExclusion Criteria:\n\n* Acute hemorrhoidal disease complicated by thrombosis or strangulation.\n* Coagulopathies.\n* Active neoplastic disease.\n* Treatment with anticoagulants and\u002For chemotherapeutic agents.\n* Hypersensitivity to active substances, especially lidocaine (and other amide-type local anesthetics) or excipients.\n* Severe hypotensive states or cardiovascular insufficiency.\n* Pregnancy or breastfeeding.\n* Participation in clinical trials involving investigational drugs.","75 Years",{"count":92,"type":20},80,"30 Days","The goal of this observational study is to evaluate the effectiveness of topical nifedipine 0.3% plus lidocaine 1.5% for uncomplicated hemorrhoidal disease. The main question it aims to answer is:\n\nDoes topical nifedipine 0.3% plus lidocaine 1.5% lower symptoms in patients with uncomplicated acute hemorrhoidal disease? Participants already taking nifedipine 0.3% plus lidocaine 1.5% as part of their regular medical care for hemorrhoidal disease will undergo four visits over a 30-day period, including two telephone contacts and two in-person visits.",[25,96,97,24,98],"Hemorrhoids Prolapse","Hemorrhoid Pain","Topical Administration",[100,101,102],"nifedipine 0.3% plus lidocaine 1.5%","uncomplicated hemorrhoidal disease","hemorrhoids symptoms","2025-12-19",{"date":105,"type":42},"2025-12-22",{"date":107,"type":42},"2025-09-02",{"date":109,"type":20},"2026-05-02",{"name":111,"class":49},"Cardarelli Hospital",{"id":113,"slug":114,"hasResults":11,"nctId":115,"briefTitle":116,"officialTitle":117,"acronym":118,"eligibilityCriteria":119,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":120,"targetDuration":4,"studyType":122,"phases":123,"briefSummary":125,"conditions":126,"keywords":127,"overallStatus":70,"whyStopped":4,"lastUpdateSubmitDate":130,"lastUpdatePostDateStruct":131,"startDateStruct":133,"completionDateStruct":135,"leadSponsor":137,"locationsCount":81},"100564128","trial-of-latex-vs-non-latex-hemorrhoid-banding-100564128","NCT06625138","Trial of Latex Vs Non-latex Hemorrhoid Banding","Single-blinded Randomized Trial of Latex Vs Non-latex Hemorrhoid Banding","NO-Tex","Inclusion Criteria:\n\n* Symptomatic grade 2-3 internal hemorrhoids undergoing rubber band ligation\n\nExclusion Criteria:\n\n* Previous hemorrhoidal banding within the past year\n* Known latex allergy\n* Pregnancy\n* Anticoagulation use\n* Bleeding disorder\n* Portal hypertension\n* Inflammatory bowel disease\n* Immunosuppression\n* Functional neurologic disorder\n* Pelvic floor dysfunction\n* Any records flagged \"break the glass\" or \"research opt out\".",{"count":121,"type":20},164,"INTERVENTIONAL",[124],"NA","This study will involve the recruitment of adult patients with hemorrhoids for whom rubber band ligation is the recommended treatment. Patients will be randomized to receive banding with a latex band or non-latex band. Our goal will be to measure the performance of latex bands vs non-latex bands.",[24,25],[128,129],"hemorrhoid","banding","2024-10-24",{"date":132,"type":42},"2024-10-28",{"date":134,"type":42},"2024-08-30",{"date":136,"type":20},"2026-10-01",{"name":138,"class":49},"Huntington Memorial Hospital"]