[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"hemorrhoids-internal\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:hemorrhoids-internal":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,45,74],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100635972","rectal-arterial-embolization-vs-band-ligation-for-the-treatment-of-internal-hemorrhoids-100635972",false,"NCT07559630","Rectal Arterial Embolization vs Band Ligation for the Treatment of Internal hemOrrhoidS","STRATOS: Single-center Randomized Controlled Trial of Rectal Arterial Embolization vs Band Ligation for the Treatment of Internal hemOrrhoidS","STRATOS","Inclusion Criteria:\n\n1. Age ≥ 18 years and less than 90 years.\n2. Ability to provide written informed consent.\n3. Documented clinical history of chronic bleeding from internal hemorrhoids.\n4. Documented presence of Goligher grade II-III internal hemorrhoids.\n5. Failed conservative treatment for bleeding hemorrhoids (e.g. fiber supplementation, topical ointments and creams, dietary modifications, stool softeners, warm baths).\n6. Able to comply with all treatments and protocol follow-up visits, in the opinion of the PI's.\n\nExclusion Criteria:\n\n1. Moderate loss of kidney function, defined as estimated glomerular filtration rate of less than 45 mL\u002Fmin.\n2. Significant arterial atherosclerosis that would limit selective angiography.\n3. Known alternative causes of GI bleeding.\n4. Allergy to iodinated contrast agents.\n5. Active infection or malignancy.\n6. Pregnancy.\n7. Active nicotine use within the last 12 months.\n8. Portal hypertension\u002Frectal varices.\n9. Uncorrectable coagulopathy (INR \\> 2; Platelet count \\\u003C100,000; PTT \\> 40 sec).\n10. Findings on baseline CTA that adversely affect treatment, based on PI's clinical judgment, including but not limited to stenosis, occlusion, or hypoplasia of the superior and\u002For middle rectal arteries.","ALL","18 Years","89 Years",{"count":21,"type":22},40,"ESTIMATED","INTERVENTIONAL",[25],"NA","The purpose of this clinical trial is to compare two standard of care non-surgical treatments for hemorrhoidal bleeding: hemorrhoidal artery embolization (HAE) versus rubber band ligation (RBL). Directly comparing these two methods may help to clarify which treatment is better for controlling hemorrhoidal bleeding, reducing symptoms, and improving patients' quality of life.\n\nHAE is a standard minimally invasive procedure to put tiny particles or coils into the blood vessel that feeds a hemorrhoid to block the blood flow (embolization). This involves using a catheter inserted into an artery, using twilight (conscious) sedation.\n\nRBL is a standard procedure that involves using small rubber bands around the base of the hemorrhoids to cut off blood flow, causing it to shrink or shrivel.",[28,29,30,31],"Hemorrhoidal Bleeding","Hemorrhoids, Internal","HAE","RBL","RECRUITING","2026-05-06",{"date":35,"type":36},"2026-05-08","ACTUAL",{"date":38,"type":22},"2026-05-29",{"date":40,"type":22},"2031-11",{"name":42,"class":43},"Jessica K. Stewart, MD","OTHER",1,{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":4,"eligibilityCriteria":51,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":52,"targetDuration":54,"studyType":55,"phases":4,"briefSummary":56,"conditions":57,"keywords":63,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":44},"100583583","cough-and-hemorrhoids-100583583","NCT06878209","Cough and Hemorrhoids","Is Cough a Predisposing Factor for Hemorrhoids? A Prospective, Analytical Study","Inclusion Criteria:\n\n1. Being 18 years of age or older\n2. Speaking and understanding Turkish\n3. To be mentally and cognitively capable of understanding the questions asked\n4. To agree to participate in the research\n5. individuals diagnosed with hemorrhoidal disease\n\nExclusion Criteria:\n\n1. Those with existing proctologic disease other than hemorrhoidal disease and pelvic floor disease\n2. Patients with previous surgery for hemorrhoidal disease\n3. Patients with hemorrhoidal disease caused by portal hypertension\n4. Patients during pregnancy and diagnosed with postpartum hemorrhoidal disease\n5. those with benign prostatic hyperplasia or neurogenic bladder that may cause increased intra-abdominal pressure",{"count":53,"type":22},134,"1 Day","OBSERVATIONAL","The aim of the study is to investigate the relationship between hemorrhoids and cough by assessing the symptoms, duration, and severity of cough in patients who will present to the general surgery outpatient clinic of Muğla Education and Research Hospital (MERH) with symptoms such as bleeding, pain, itching, fecal leakage, prolapse, and mucus discharge. These patients will be diagnosed with hemorrhoidal disease through rectal examination to detect anal pathology and will be graded according to mucosal prolapse. Our study will aim to determine whether cough is a predisposing factor for hemorrhoids by evaluating the presence, duration, and frequency of cough symptoms in patients with hemorrhoids. The study will be designed as a cross-sectional, analytical, and descriptive study. Between March 2025 and June 2025, patients with newly diagnosed hemorrhoids who will present to the MEAH General Surgery Outpatient Clinic will undergo physical examinations and will be assessed for cough symptoms. Evaluations will include height and weight measurements, the Leicester Cough Questionnaire, the Cough Visual Analog Scale (VAS) questionnaire, duration of cough (categorized as acute if shorter than 4 weeks, or chronic if longer than 4 weeks), timing of cough (day, night, or all day), comorbidities (such as COPD, asthma, chronic bronchitis, interstitial lung disease, idiopathic pulmonary fibrosis, and others), and smoking history (active, former, or never smoked). The primary endpoint will be to compare the relationship between the severity of hemorrhoids and the duration and frequency of cough in patients with both conditions. The secondary endpoint will be to compare the grade of hemorrhoids with comorbid chest diseases in these patients. The tertiary endpoint will be to compare the degree of hemorrhoids with the smoking history of patients who have both hemorrhoids and cough.",[58,59,60,61,62,29],"Hemorrhoid","Cough","Cough Duration","Cough Frequency","Cough Severity",[64],"cough, hemorrhoid","2025-05-08",{"date":67,"type":36},"2025-05-11",{"date":69,"type":36},"2025-03-14",{"date":71,"type":22},"2025-10-14",{"name":73,"class":43},"Muğla Sıtkı Koçman University",{"id":75,"slug":76,"hasResults":11,"nctId":77,"briefTitle":78,"officialTitle":79,"acronym":80,"eligibilityCriteria":81,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":82,"enrollmentInfo":83,"targetDuration":4,"studyType":23,"phases":85,"briefSummary":86,"conditions":87,"keywords":92,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":94,"lastUpdatePostDateStruct":95,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":5},"100499342","sci-pex-study---safety-and-performance-of-pexyeazy-a-device-for-treatment-of-hemorrhoids-100499342","NCT05782010","SCI-Pex Study - Safety and Performance of PexyEazy®, a Device for Treatment of Hemorrhoids","SCI-Pex, a Multi-center, Prospective, Non-controlled Investigation to Evaluate the Safety and Performance of PexyEazy®, a Device for Treatment of Hemorrhoids","SCI-Pex","Inclusion Criteria:\n\n* Adult\n* Hemorrhoidal disease grade II and III\n* American Society of Anesthesiologists (ASA) classification I-III.\n\nExclusion Criteria:\n\n* Previous surgical treatment for hemorrhoids by all methods except rubber band ligation or sclerosing injection therapy within the last 3 years.\n* Previous surgical treatment with rubber band ligation or injection therapy within the last 2 months.\n* More than three surgical treatments with rubber band ligation or sclerosing injection therapy within the last 3 years.\n* Under medication with immunosuppressive drugs and\u002For anticoagulant drugs (not including 75mg acetylsalicylic acid) and not able to interrupt the anticoagulant drug medication or replace it with low molecular weight heparin for 5 days.\n* Have ulcerative colitis, Crohn's disease or other intestinal inflammatory disease or presence of inflamed or thickened mucosa of the rectum.\n* Presence of anal fissure, anal stenosis, stricture, fistulas or ulcers in the rectal area.\n* The rectum has not been prepared prior to the investigation with rectal enema and is contaminated with feces that cannot easily be removed.\n* Have schizophrenia, untreated depression or other mental illness or conditions that may affect judgment, sensation of pain or inability to complete the follow-up.\n* Under medication of morphine or other strong painkillers, not including paracetamol.\n* Fecal incontinence (not including soiling due to hemorrhoidal disease), or conditions with impaired sensation in the rectal area or impaired function of the anal sphincter.\n* Previous rectal radiation.\n* Rectal cancer or previous surgery due to rectal cancer.\n* Pregnancy\n* Hypercoagulability disorders or diseases that result in increased risk of bleeding.\n* Impaired immune system or condition that increases the risk of infection.","84 Years",{"count":84,"type":22},35,[25],"The SCI-Pex study is a multicenter, prospective, non-controlled investigation on PexyEazy®, a new device for treatment of hemorrhoids based on the mucopexy method. Mucopexy is a well established method where sutures are applied above the hemorrhoids. When knots are tied, the hemorrhoids are lifted inwards to their normal position, which makes them swell down and symptoms disappears. PexyEazy® perform a mukopexy in a semiautomatic, faster and easier way on awake patient in less than 10 minutes. The SCI-Pex study will evaluate the safety and performance of PexyEazy on 35 patients with hemorrhoids grade II and III with a follow-up after 1 week, 3 months and 1 years. Adverse events, pain and other complications will be recorded, quality of life and hemorrhoid symptom questionnaires and clinical examination after 3 months and 1 year will be monitored to evaluate the result after a PexyEazy® procedure.",[88,29,89,90,91],"Hemorrhoids","Suture; Complications, Infection or Inflammation","Rectal Diseases","Gastrointestinal Diseases",[93],"PexyEazy","2025-03-04",{"date":96,"type":36},"2025-03-07",{"date":98,"type":36},"2023-06-15",{"date":100,"type":22},"2026-05-30",{"name":102,"class":103},"Developeration AB","INDUSTRY"]