[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"heparin\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:heparin":29},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":43},"100524471","phase-4-the-effect-of-act-and-tranexamic-acid-on-bleeding-in-cardiac-surgery-100524471",false,"NCT06109155","The Effect of ACT and Tranexamic Acid on Bleeding in Cardiac Surgery","The Dose Effect of Activated Clotting Time and Tranexamic Acid on Bleeding in Adult Cardiac Surgery","Inclusion Criteria:\n\n* adult, cardiac surgery with cardiopulmonary bypass\n\nExclusion Criteria:\n\n* pregnant\n* emergency procedure\n* immune compromised\n* aortic surgery\n* end-stage renal disease\n* liver disease\n* critical status\n* incomplete clinical data","ALL","18 Years",{"count":19,"type":20},150,"ESTIMATED","INTERVENTIONAL",[23],"PHASE4","The goal of this clinical trial is to the dose effect of tranexamic acid and the level of ACT on bleeding in adult cardiac surgery.\n\nThe main questions it aims to answer are:\n\n1. Does higher dose of tranexamic acid reduce the amount of bleeding and blood transfusion?\n2. Does lower ACT level during cardiac surgery reduce the amount of bleeding and blood transfusion?\n\nParticipants will divided into four groups which have different tranexamic acid dose and ACT level during cardiac surgery to see if there is any different in the amount of bleeding and blood transfusion.",[26,27,28,29,30],"Surgery, Cardiac","Tranxemic Acid","Activated Clotting Time","Heparin","Cardiopulmonary Bypass","RECRUITING","2024-02-20",{"date":34,"type":35},"2024-02-21","ACTUAL",{"date":37,"type":35},"2024-02-08",{"date":39,"type":20},"2026-12-31",{"name":41,"class":42},"Taichung Veterans General Hospital","OTHER",2]