[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"hepatobiliary-surgery\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:hepatobiliary-surgery":31},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,47],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100644754","remimazolam-on-the-incidence-of-postoperative-acute-kidney-injury-100644754",false,"NCT07674719","Remimazolam on the Incidence of Postoperative Acute Kidney Injury","The Effect of Intraoperative Remimazolam Administration on the Incidence of Postoperative Acute Kidney Injury After Hepatobiliary and Pancreatic Surgery : a Prospective Randomized Controlled Trial","Inclusion Criteria:\n\n* Ages 19 or older and under 85\n* Patients scheduled to undergo elective hepatopancreatic surgery under general anesthesia\n* American Society of Anesthesiologists (ASA) physical grade 1-3\n* Those who voluntarily consented to a written informed consent form prior to participation in the study\n\nExclusion Criteria:\n\n* Patients with hypersensitivity to other benzodiazepine drugs, including remimazolam, and to the components of this drug (e.g., patients with severe hypersensitivity to dextran 40)\n* Patients with hypersensitivity to propofol\n* Patients with underlying conditions: liver, neurological disorders, or acute narrow-angle glaucoma\n* Patients with severe or acute respiratory failure\n* Patients in shock or a coma\n* Patients taking TCA antidepressants\n* Patients with preoperative chronic kidney disease","ALL","19 Years","85 Years",{"count":20,"type":21},78,"ESTIMATED","INTERVENTIONAL",[24],"NA","We hypothesized that in patients undergoing elective hepatobiliary-pancreatic surgery, the group in which anesthesia is induced and maintained with remimazolam during surgery would maintain hemodynamic stability and reduce the incidence of postoperative acute kidney injury compared to propofol. The purpose is to provide practical evidence for perioperative management differentiated from other surgeries for hepatobiliary-pancreatic surgery patients for whom intraoperative fluid therapy is restricted.",[27,28,29,30,31,32,33],"Remimazolam","Propofol","Acute Kidney Injury","Hemodynamic Stability","Hepatobiliary Surgery","Fluid Therapy","Fluid Therapy DURING SURGERY","NOT_YET_RECRUITING","2026-06-24",{"date":37,"type":38},"2026-06-29","ACTUAL",{"date":40,"type":21},"2026-06-26",{"date":42,"type":21},"2028-06-26",{"name":44,"class":45},"Seoul National University Bundang Hospital","OTHER",1,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":53,"eligibilityCriteria":54,"healthyVolunteers":11,"sex":16,"minAge":55,"maxAge":4,"enrollmentInfo":56,"targetDuration":4,"studyType":22,"phases":58,"briefSummary":59,"conditions":60,"keywords":62,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":46},"100638009","prophylactic-antibiotics-in-preventing-surgical-site-infection-after-hepatobiliary-surgery-in-high-resistant-settings-100638009","NCT07620223","Prophylactic Antibiotics in Preventing Surgical Site Infection After Hepatobiliary Surgery in High-Resistant Settings","Prophylactic Antibiotics in Preventing Surgical Site Infection After Hepatobiliary Surgery in High-Resistant Settings: A Randomized Clinical Trial","PASH","Inclusion Criteria:\n\n* Adult patients aged ≥18 years;\n* Deemed eligible for elective hepatobiliary surgery;\n* Demonstrated comprehension of the study nature and expressed willingness to comply with trial procedures;\n* Capable of providing written informed consent.\n\nExclusion Criteria:\n\n* History of β-lactam allergy or hypersensitivity\n* Uncontrolled preoperative infection;\n* Current or recent (within the preceding month) systemic corticosteroid administration;\n* Severe hepatic or renal impairment;\n* Pregnancy or lactation;\n* Concurrent enrolment in another clinical trial;\n* Any other condition deemed by the investigator to render the patient unsuitable for study participation.","18 Years",{"count":57,"type":21},378,[24],"To analyse the efficacy of different preoperative prophylactic antimicrobial regimens for perioperative infection prevention in patients undergoing hepatobiliary surgery in a high antimicrobial resistance setting.",[31,61],"Prophylactic Antibiotics",[31,63,64,65],"Antimicrobial resistance","Prophylactic antibiotic","Surgical site infection","RECRUITING","2026-05-27",{"date":69,"type":38},"2026-06-02",{"date":71,"type":38},"2026-05-24",{"date":73,"type":21},"2029-01-31",{"name":75,"class":45},"The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School"]