[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"hereditary-disease\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:hereditary-disease":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,47],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":4,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":29,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100357259","the-china-neonatal-genomes-project-100357259",false,"NCT03931707","The China Neonatal Genomes Project","CNGP","Inclusion Criteria:\n\n* 1\\. Both parents are of Chinese origin;\n* 2\\. Postnatal age less than 28 days;\n* 3\\. Can be retained to at least 1ml venous blood sample;\n* 4\\. Biological parent or guardian's informed consent.\n\nExclusion Criteria:\n\n* 1\\. the nationality of one of the parents is not the Han nationality or other national minorities;\n* 2\\. reluctance of parents to use genetic sequencing data for subsequent research;\n* 3\\. parents under 18 years of age or incapacitated for decision-making;\n* 4\\. subjects older than 28 days.\n* 5\\. multiple pregnancies;\n* 6\\. lack of access to biological samples from which DNA can be extracted;\n* 7\\. failure to sign informed consent",true,"ALL","28 Days",{"count":20,"type":21},100000,"ESTIMATED","OBSERVATIONAL","The project will carry out the genetic testing of 100000 neonates in the next 5 years. The aim of the project is to construct the Chinese neonatal genome database, establish the genetic testing standard of neonatal genetic diseases, and promote the industrialization of neonatal genetic disease gene testing, improve the training system for genetic counseling.",[25,26,27,28],"Newborn","Hereditary Disease","Genetic Predisposition to Disease","Defect, Congenital",[25,26,27,28,30,31,32,33],"Genome Sequencing","Exome Sequencing","Newborn Screening","Genetic Diseases, Inborn","RECRUITING","2026-03-13",{"date":37,"type":38},"2026-03-16","ACTUAL",{"date":40,"type":38},"2016-08-08",{"date":42,"type":21},"2026-12-30",{"name":44,"class":45},"Children's Hospital of Fudan University","OTHER",1,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":51,"acronym":4,"eligibilityCriteria":52,"healthyVolunteers":11,"sex":17,"minAge":4,"maxAge":53,"enrollmentInfo":54,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":56,"conditions":57,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":61,"startDateStruct":63,"completionDateStruct":65,"leadSponsor":67,"locationsCount":46},"100432009","study-on-early-genetic-screening-and-precise-strategy-of-neonatal-critical-illness-100432009","NCT04905537","Study on Early Genetic Screening and Precise Strategy of Neonatal Critical Illness","Inclusion Criteria:\n\n* Postnatal age less than 100 days;\n* Perinatal death after 20 weeks of gestation (more than 500 g)\n* Can be retained biological samples for genetic screening;\n* Biological parent or guardian's informed consent.\n\nExclusion Criteria:\n\n* Reluctance of parents to use genetic sequencing data for subsequent research;\n* Parents under 18 years of age or incapacitated for decision-making;\n* subjects older than 100 days;\n* Perinatal death less than 20 weeks of gestation or weight less than 500 g;\n* Inherited metabolic diseases with chromosomal abnormalities;\n* Multiple pregnancies;\n* Lack of access to biological samples from which DNA can be extracted;\n* Failure to sign informed consent.","100 Days",{"count":55,"type":21},4000,"The researchers hope to establish an overall program of early genetic screening for neonatal critical illness in China, and to develop precise intervention strategies to assist clinical diagnosis and treatment of hereditary critical illness.",[58,26,25,59],"Genetic Screening","Stillbirth","2025-02-19",{"date":62,"type":38},"2025-02-20",{"date":64,"type":38},"2021-01-01",{"date":66,"type":21},"2025-12",{"name":44,"class":45}]