[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"hernia-ventral\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:hernia-ventral":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,7,0,[8,46,73,110,144,171,199],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":4,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":30,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100422368","ventral-or-inguinal-hernia-robotically-repaired-with-ovitex-mesh-100422368",false,"NCT04779918","Ventral or Inguinal Hernia, Robotically Repaired With OviTex Mesh","A Prospective Study Evaluating the Clinical Outcomes of Ventral or Inguinal Hernias Treated Robotically With OviTex® Reinforced Tissue Matrix","BRAVOII","Inclusion Criteria:\n\n1. Subject suffers from a ventral or inguinal hernia that requires surgical repair with the use of an implant to reinforce or replace weakened or missing tissue.\n2. The patient is scheduled for an elective robotic approach with the use of OviTex LPR, OviTex Core Permanent, OviTex 1S Permanent, or OviTex IHR.\n3. The size of the implant needed for repair is expected to be less than or equal to 15 x 25 cm for OviTex LPR and 25 x 40 cm for OviTex Core Permanent and OviTex 1S Permanent, with no size limitation for OviTex IHR.\n4. Subject meets CDC\u002FSSI Wound Classification Class I (Clean), Class II (Clean-Contaminated) or Class III (Contaminated) criteria.\n5. Subject is willing and able to sign an informed consent for the study and has signed the IRB approved Informed Consent form for this study.\n6. Subject is able to complete Quality of Life (QoL) and pain questionnaires.\n7. Subject is at least 21 years old.\n8. Subject is willing to comply and able to participate fully in, and for the full duration of, the study including follow-up requirements.\n\nExclusion Criteria at Baseline:\n\n1. Subject has a BMI of \\> 40\n2. Subject meets CDC\u002FSSI Wound Classification Class IV (Dirty-Infected) criteria\n3. Subject is female and is pregnant or plans to become pregnant during the course of the study.\n4. Subject has a life expectancy of \\\u003C 2 years making it unlikely that the subject will successfully achieve two-year follow-up.\n5. Subject has recent history of drug or alcohol abuse (in last 3 years).\n6. Subject has an allergy to ovine-derived products.\n7. Subject has participated in another clinical trial within the past 30 days or is currently involved in another clinical trial.\n8. Subject has a strangulated hernia.\n\nExclusion Criteria Intraoperative:\n\n1. Subject requires implant that cannot be introduced into the surgical site during the procedure via port or an existing incision.\n2. Subject unable to receive OviTex LPR, OviTex Core Permanent, OviTex 1S Permanent, or OviTex IHR at time of surgery.",true,"ALL","21 Years",{"count":21,"type":22},160,"ESTIMATED","INTERVENTIONAL",[25],"NA","This study is designed to evaluate the post-operative complications and hernia recurrence following the use of OviTex in subjects with ventral or inguinal hernias. Up to 160 subjects will participate in the study from up to 20 investigator sites.",[28,29],"Hernia, Ventral","Hernia, Inguinal",[31,32],"use of mesh","robotic hernia repair","RECRUITING","2026-04-29",{"date":36,"type":37},"2026-05-05","ACTUAL",{"date":39,"type":37},"2021-04-29",{"date":41,"type":22},"2029-12-30",{"name":43,"class":44},"Tela Bio Inc","INDUSTRY",10,{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":4,"eligibilityCriteria":52,"healthyVolunteers":11,"sex":18,"minAge":53,"maxAge":4,"enrollmentInfo":54,"targetDuration":4,"studyType":56,"phases":4,"briefSummary":57,"conditions":58,"keywords":4,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":72},"100583714","a-study-to-understand-the-utility-of-the-force-feedback-instruments-in-robotic-procedures-using-da-vinci-5-robot-100583714","NCT06879912","A Study to Understand the Utility of the Force Feedback Instruments in Robotic Procedures Using da Vinci 5 Robot","A Prospective, Post-Market Study to Evaluate the Clinical Utility of the Force Feedback Instruments in RAS Procedures Using the da Vinci 5 Surgical System","Pre-Operative Inclusion Criteria:\n\n1. Age 22 years or older\n2. ASA ≤ 3\n3. The clinical decision has been made to perform multi-port robotic assisted surgery with da Vinci 5 with Force Feedback instruments for the study specified procedure as primary procedure prior to enrollment in the study\n4. Subject or a legally authorized representative is able to provide written informed consent using the study informed consent form prior to the study\n5. Subject is willing and able to comply with the study protocol requirements including follow up schedule\n\nPre-operative Exclusion Criteria:\n\n* Subject receiving an emergent procedure\n* Subject planned to undergo major concomitant surgery for the treatment of a different medical condition than was originally planned\n* Subject with previous ipsilateral surgery (open, endoscopic or robotic) with the same surgical indication\n* Subject with past or ongoing medical conditions (for example: inflammatory bowel disease) which, in the judgment of the Investigator, puts them at high risk for surgery and not appropriate for the study\n* Subject is pregnant or suspected to be pregnant or breastfeeding\n* Subject has any other condition or personal circumstance that, in the judgment of the Investigator, might interfere with the collection of complete quality data\n* Subject is currently participating in or has participated in a study of an investigational agent or a significant risk investigational device study within the past 6 months\n* Subject belongs to a vulnerable population.\n* Subject is contraindicated for anesthesia or surgery.\n* Subject has had previous neoadjuvant therapy, previous chemotherapy, immunotherapy, and\u002For radiation therapy for the treatment of the cancer to be resected within the past 6 months\n\nIntra-operative Exclusion Criteria\n\n* Subject with hemodynamic or respiratory instability, which precludes the Investigator from performing the RAS.\n* Subject in whom inadequate visualization makes a minimally invasive approach not feasible, as determined from the investigator assessment prior to docking the robot.\n* Subject with adhesions, scarring and disease status in the body which in the opinion of the investigator limits the ability to perform the minimally invasive procedure.","22 Years",{"count":55,"type":22},200,"OBSERVATIONAL","The goal of this observational study is to understand the utility of force feedback instruments in surgeries that are done using the da Vinci 5 robot.",[29,28,59,60,61,62],"Colorectal","Thoracic","Gynecologic","Partial Nephrectomy","2026-02-23",{"date":65,"type":37},"2026-02-25",{"date":67,"type":37},"2025-05-22",{"date":69,"type":22},"2026-08",{"name":71,"class":44},"Intuitive Surgical",5,{"id":74,"slug":75,"hasResults":11,"nctId":76,"briefTitle":77,"officialTitle":78,"acronym":79,"eligibilityCriteria":80,"healthyVolunteers":11,"sex":18,"minAge":81,"maxAge":4,"enrollmentInfo":82,"targetDuration":4,"studyType":23,"phases":84,"briefSummary":85,"conditions":86,"keywords":90,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":100,"lastUpdatePostDateStruct":101,"startDateStruct":103,"completionDateStruct":105,"leadSponsor":107,"locationsCount":109},"100417629","gore-enform-biomaterial-product-study-100417629","NCT04718168","GORE® ENFORM Biomaterial Product Study","GORE® ENFORM Biomaterial Product Study: A Study to Describe Multi-use Biomaterial Performance in Hernia Patients","ENF 18-06","Pre-procedure Inclusion Criteria:\n\nThe subject is \u002F has:\n\n1. At least 18 years old at the time of informed consent. Minimum age required by state regulations (as applicable).\n2. An expected scored Class I (Clean) surgical wound using CDC Surgical Wound Classification system.\n3. A planned implant with GORE® ENFORM Biomaterial for a single site ventral or hiatal hernia repair as suture line reinforcement.\n4. An expected scored Grade 1 or Grade 2 using the Ventral Hernia Working Group Grading system.\n5. Willing to provide informed consent and comply with follow-up requirements.\n\nPre-procedure Exclusion Criteria:\n\nThe subject is \u002F has:\n\n1. Treated in another drug or medical device study within 1 year of study enrollment.\n2. Implanted with GORE® ENFORM Biomaterial in the reconstruction of cardiovascular defects.\n3. Hernia repair expected to be performed as part of a bridged procedure (i.e., expected inability to perform primary closure of fascia or crura, patients requiring permanent support from the device).\n4. A BMI \\>40.\n5. Evidence of a systemic infection.\n6. Cirrhosis or undergoing dialysis.\n7. A wound-healing disorder.\n8. Immunocompromised such as, with HIV or transplant, or receiving chemo or radiation therapy.\n9. Expected to undergo mesh implantation in conjunction with any bariatric procedure and \u002F or panniculectomy procedure.\n10. A stoma.\n11. Co-morbid conditions that may limit their ability to comply with study and follow-up requirements.\n12. Positive pregnancy or lactation status as confirmed by site standard of care.\n13. Hernias requiring treatment within multiple body regions or expected use of multiple hernia mesh devices.\n\nPost-procedure Inclusion Criteria\n\nAt the time of index procedure, the subject is \u002F has:\n\n1. At least 18 years old. Minimum age required by state regulations (as applicable).\n2. Implanted with GORE® ENFORM Biomaterial for a single site ventral or hiatal hernia repair as suture-line reinforcement on or before 365 days prior to site protocol amendment 3 approval date.\n3. Unless there is an Informed Consent waiver issued by the Institutional Review Board (IRB), an Informed Consent Form (ICF) signed by subject.\n\nPost-procedure Exclusion Criteria\n\nAt the time of index procedure, the subject is \u002F has:\n\n1. Treated in another drug or medical device study within 1 year of study enrollment.\n2. Implanted with GORE® ENFORM Biomaterial in the reconstruction of cardiovascular defects.\n3. Hernia repair that was performed as part of a bridged procedure (i.e., inability to perform primary closure of fascia or crura, patients requiring permanent support from the device).\n4. A BMI \\>40.\n5. Evidence of a systemic infection.\n6. Cirrhosis or undergoing dialysis.\n7. A wound-healing disorder.\n8. Immunocompromised such as, with HIV or transplant, or receiving chemo or radiation therapy.\n9. Underwent mesh implantation in conjunction with any bariatric procedure and \u002F or panniculectomy procedure.\n10. A stoma.\n11. Co-morbid conditions that may limit their ability to comply with study and follow-up requirements.\n12. Positive pregnancy or lactation status as confirmed by site standard of care.\n13. Hernias requiring treatment within multiple body regions or expected use of multiple hernia mesh devices.","18 Years",{"count":83,"type":22},245,[25],"A prospective, retrospective, non-randomized, multicenter study with two independent hernia study cohorts (Ventral \u002F Incisional Hernia Repair and Diaphragmatic \u002F Hiatal Hernia Repair). The primary objective of this study is to collect GORE® ENFORM Biomaterial product commercial-use data on device functional performance and short-term patient experience.",[28,87,88,89],"Hernia, Hiatal","Hernia, Diaphragmatic","Incisional Hernia",[91,92,93,94,95,96,97,98,99],"hernia","ventral","hiatal","diaphragmatic","incisional","mesh","Gore","W.L. Gore","Enform","2026-02-17",{"date":102,"type":37},"2026-02-18",{"date":104,"type":37},"2021-05-17",{"date":106,"type":22},"2026-09",{"name":108,"class":44},"W.L.Gore & Associates",9,{"id":111,"slug":112,"hasResults":11,"nctId":113,"briefTitle":114,"officialTitle":115,"acronym":116,"eligibilityCriteria":117,"healthyVolunteers":11,"sex":18,"minAge":81,"maxAge":4,"enrollmentInfo":118,"targetDuration":4,"studyType":23,"phases":120,"briefSummary":121,"conditions":122,"keywords":126,"overallStatus":134,"whyStopped":4,"lastUpdateSubmitDate":135,"lastUpdatePostDateStruct":136,"startDateStruct":138,"completionDateStruct":139,"leadSponsor":141,"locationsCount":4},"100625423","compliance-guided-abdominal-wall-closure-strategy-in-large-ventral-hernia-repair-100625423","NCT07422441","Compliance-Guided Abdominal Wall Closure Strategy in Large Ventral Hernia Repair","Impact of a Compliance-Guided Intraoperative Abdominal Wall Closure Decision Strategy on Early Postoperative Respiratory Failure After Large Ventral Hernia Repair Following Preoperative Botulinum Toxin A","CLOSE-STAT","Inclusion Criteria:\n\n* Age 18 years or older\n* Elective repair of a large ventral abdominal wall hernia (including incisional hernia)\n* Preoperative botulinum toxin A preparation performed as part of the local prehabilitation pathway\n* Preoperative abdominal CT available\n* General anesthesia with mechanical ventilation and feasibility of standardized intraoperative respiratory mechanics measurements\n\nExclusion Criteria:\n\n* Severe preoperative respiratory failure judged to preclude standardized intraoperative respiratory mechanics assessment\n* Inability to obtain reliable static respiratory system compliance measurements at predefined timepoints\n* Hemodynamic instability preventing protocolized measurements (as judged by the anesthesiologist)",{"count":119,"type":22},50,[25],"People undergoing repair of large ventral hernias can develop breathing problems after surgery, especially around the time when the abdominal wall is closed. During closure, pressure inside the abdomen may increase and lung mechanics can worsen. This study will evaluate a structured intraoperative decision approach that uses standard anesthesia measurements of static respiratory system compliance at predefined timepoints to support the choice of abdominal wall closure technique. The main goal is to assess the rate of early postoperative respiratory failure within 72 hours after surgery.",[28,123,124,125],"Hernia Incisional","Postoperative Complications","Respiratory Insufficiency",[127,128,129,130,131,132,133],"adbominal wall closure","static compliance","respiratory system compliance","intraoperative monitoring","intra-abdominal pressure","complex hernia repair","botulinum toxin a","NOT_YET_RECRUITING","2026-02-12",{"date":137,"type":37},"2026-02-20",{"date":137,"type":22},{"date":140,"type":22},"2026-11-01",{"name":142,"class":143},"Swissmed Hospital","OTHER",{"id":145,"slug":146,"hasResults":11,"nctId":147,"briefTitle":148,"officialTitle":149,"acronym":150,"eligibilityCriteria":151,"healthyVolunteers":11,"sex":18,"minAge":81,"maxAge":4,"enrollmentInfo":152,"targetDuration":4,"studyType":23,"phases":154,"briefSummary":155,"conditions":156,"keywords":159,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":162,"lastUpdatePostDateStruct":163,"startDateStruct":165,"completionDateStruct":167,"leadSponsor":169,"locationsCount":72},"100617269","preoptimisation-in-ventral-hernia-surgery-100617269","NCT07316426","Preoptimisation in Ventral Hernia Surgery","Preoptimisation in Ventral Hernia Surgery- a Randomised Trial","PreOpt","Inclusion Criteria:\n\n* Patients with a ventral hernia with a defect width of at least 4 cm.\n* Symptom burden related to the hernia sufficient to justify surgical intervention.\n* Age ≥ 18 years.\n\nExclusion Criteria:\n\n* Expected survival of less than three years.\n* Inability to comprehend oral and written information or to provide informed consent.\n* Acute complication of the hernia requiring emergency surgical intervention.\n* General condition characterised by severe limitations in physical functional capacity.",{"count":153,"type":22},130,[25],"The study is a multicentre, single-blinded, randomised controlled trial. Ventral hernia patients with an aperture width between four and eight centimetres are randomised to either participation in a multimodal preoptimisation programme, including interventions to increase physical activity, promote weight loss, and optimise the treatment of comorbidities, or to surgery without structured preoptimisation. The primary endpoint is complications at three months postoperatively. During surgery, biopsies of skin, muscle, and fascia will be collected, along with pre- and postoperative blood samples, to analyse the molecular effects of preoptimisation, particularly in relation to collagen metabolism.",[157,28,123,158],"Hernia","Hernia, Umbilical",[160,161],"preoptimisation","prehabilitation","2025-12-18",{"date":164,"type":37},"2026-01-05",{"date":166,"type":37},"2025-09-22",{"date":168,"type":22},"2029-09-01",{"name":170,"class":143},"Umeå University",{"id":172,"slug":173,"hasResults":11,"nctId":174,"briefTitle":175,"officialTitle":176,"acronym":177,"eligibilityCriteria":178,"healthyVolunteers":11,"sex":18,"minAge":81,"maxAge":4,"enrollmentInfo":179,"targetDuration":4,"studyType":23,"phases":181,"briefSummary":182,"conditions":183,"keywords":185,"overallStatus":134,"whyStopped":4,"lastUpdateSubmitDate":189,"lastUpdatePostDateStruct":190,"startDateStruct":192,"completionDateStruct":194,"leadSponsor":196,"locationsCount":198},"100589378","quadratus-lumborum-versus-placebo-in-open-ventral-hernia-repair-100589378","NCT06953635","Quadratus Lumborum Versus Placebo in Open Ventral Hernia Repair","Quadratus Lumborum Blocks for Pain Control Following Open Ventral Hernia Repair: A Double Blinded Randomized Control Trial","VHR","Inclusion Criteria:\n\n1. \\>18 years of age\n2. Able to read and understand study procedures\n3. Willing to participate and sign an informed consent form\n4. Open approaches to ventral hernia repair\n5. Clean (CDC Class I), clean-contaminated (CDC Class II)\n6. Elective surgery\n7. Mesh placed in the retromuscular position\n\nExclusion Criteria:\n\n1. Dirty-Infected cases (CDC Class IV): Old traumatic wounds with retained devitalized tissue and those that involve existing clinical infection or perforated viscera\n2. Patient has a contraindication to receiving the drug and\u002For procedure: allergy\u002Fsensitivity to the drug, coagulopathy, abdominal wall infection at the drug administration site, systemic infection, anatomical distortion, neuropathy\n3. Emergent procedure\n4. Mesh not placed",{"count":180,"type":22},70,[25],"The purpose of this study is to determine whether using a QL block is better than placebo (a look-alike substance that contains no drug) in lowering the amount of opioids you need for pain relief in the first 24 hours and if it improves your recovery following a ventral hernia repair.\n\nParticipants will be asked to complete a questionnaire before surgery and again at their 30-day follow up. You will also be asked to complete a pain diary 24 hours after surgery and attend a follow-up visit approximately 30 days after surgery.\n\nThe following information will be collected from you or your medical record:\n\n1. Pain medications given to you during surgery.\n2. Pain medications prescribed to you after surgery, including medication name, dose, units, and frequency.\n3. Pain levels during the first 24 hours after surgery.\n4. Your total hospital length of stay after surgery.\n5. Any complications that you may have experienced after surgery.\n6. Demographic information, medical history as well as details about your hernia repair surgery.",[28,184],"Pain Management",[186,187,188],"Regional Anesthesia","Postoperative Pain","Ventral Hernia Repair","2025-04-29",{"date":191,"type":37},"2025-05-01",{"date":193,"type":22},"2025-06-01",{"date":195,"type":22},"2026-02-28",{"name":197,"class":143},"University of Tennessee Graduate School of Medicine",1,{"id":200,"slug":201,"hasResults":11,"nctId":202,"briefTitle":203,"officialTitle":204,"acronym":4,"eligibilityCriteria":205,"healthyVolunteers":11,"sex":18,"minAge":206,"maxAge":207,"enrollmentInfo":208,"targetDuration":4,"studyType":23,"phases":210,"briefSummary":211,"conditions":212,"keywords":215,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":220,"lastUpdatePostDateStruct":221,"startDateStruct":223,"completionDateStruct":225,"leadSponsor":227,"locationsCount":198},"100495670","optimization-of-surgical-treatment-of-patients-with-incisional-ventral-hernias-100495670","NCT05734222","Optimization of Surgical Treatment of Patients With Incisional Ventral Hernias","Optimization of Surgical Treatment of Patients With Postoperative Median and Median-lateral Ventral Hernias","Inclusion Criteria:\n\n* The study will include patients with postoperative ventral hernias of median and lateral localization and an average hernial gate width from 4.1 to 15 cm (W2-W3 according to the EHS classification).. The size of the hernial gate is determined by CT.\n\nExclusion Criteria:\n\n* Patients without postoperative ventral hernias median and lateral localization","25 Years","88 Years",{"count":209,"type":22},110,[25],"The goal of our work of optimization of the treatment of postoperative hernias is to improve the results of treatment of patients with median and median-lateral postoperative hernias of medium (W2) and large (W3) sizes by developing new surgical techniques. The main questions it aims to answer are:\n\n1. To study the topographic and variant anatomy of vessels and nerves in the retromuscular, preperitoneal, postperitoneal and pre-abdominal cell spaces of the anterior abdominal wall. To determine the most probable sources of blood flow and lymph from the anatomical formations forming the bed of the endoprosthesis.\n2. To develop technical, surgical techniques that allow to form an implant bed with minimal traumatization of blood vessels and nerves and reduce the risk of postoperative complications.\n3. To develop a technique for plasty of the anterior abdominal wall in mid-lateral postoperative hernias with a combination of retromuscular and subaponeurotic spaces.\n\nThe researchers will compare an experimental group in which a new method of preparing the implant place will be used and a control group in which standard methods of treating postoperative ventral hernias were used to see whether the new method affects the improvement of the postoperative period and the reduction of complications.",[28,213,214],"Hernias Intestinal","Hernia Abdominal Wall",[157,216,217,218,219],"median","median-lateral","median-lateral Incisional hernia","Incisional","2024-12-31",{"date":222,"type":37},"2025-01-01",{"date":224,"type":37},"2022-09-29",{"date":226,"type":22},"2025-05-23",{"name":228,"class":143},"Samara State Medical University"]