[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"high-anal-fistula\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:high-anal-fistula":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,47],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100618673","tropis-versus-coring-out-fistulectomy-in-high-anal-fistula-100618673",false,"NCT07334678","TROPIS Versus Coring Out Fistulectomy in High Anal Fistula","Early Results of Transanal Opening of the Intersphincteric Space (TROPIS) Versus Coring Out Fistulectomy in Management of High Anal Fistulas: A Randomized Clinical Trial","TROCO-HAF","Inclusion Criteria:\n\n* Patients with high anal fistula ( involving more than 1\u002F3 of the sphincter complex), whether de novo or recurrent\n\nExclusion Criteria:\n\n* Patients with fistula secondary to malignancy, inflammatory bowel disease, trauma or radiation\n* Patients with Low anal fistula\n* Patient with preoperative fecal incontinence\n* Previous levator ani muscle injury","ALL","18 Years",{"count":20,"type":21},64,"ESTIMATED","INTERVENTIONAL",[24],"NA","High anal fistulas represent a surgical challenge due to high recurrence rates and risk of postoperative fecal incontinence. Several sphincter-preserving techniques have been developed to address these issues. Coring Out fistulectomy is a traditional sphincter-saving approach, while Transanal Opening of the Intersphincteric Space (TROPIS) is a recently introduced technique with promising outcomes. This randomized clinical trial aims to compare the efficacy, safety, and patient outcomes of TROPIS versus coring out fistulectomy in the management of high complex anal fistulas.",[27],"High Anal Fistula",[29,30,31,32,33],"TROPIS","Intersphincteric Space","Coring Out Fistulectomy","High anal fistulas","Sphincter-Preserving Surgery","RECRUITING","2026-05-23",{"date":37,"type":38},"2026-05-27","ACTUAL",{"date":40,"type":38},"2025-07-08",{"date":42,"type":21},"2026-06-01",{"name":44,"class":45},"Cairo University","OTHER",1,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":4,"eligibilityCriteria":53,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":54,"targetDuration":4,"studyType":22,"phases":56,"briefSummary":57,"conditions":58,"keywords":60,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":46},"100632962","ifoc-compared-with-lift-in-high-anal-fistula-100632962","NCT07520500","IFOC Compared With LIFT in High Anal Fistula","Early Outcomes of Intra-anal Fistulotomy With Fistula Opening Closure (IFOC) Compared With Ligation of the Intersphincteric Fistula Tract (LIFT) in High Anal Fistula: A Pilot Randomized Controlled Trial","Inclusion Criteria:\n\n* Patients with high anal fistula from both gender\n\nExclusion Criteria:\n\n* Patient with preoperative fecal incontinence\n* Fistula secondary to colorectal malignancy\n* Patients with inflammatory bowel disease\n* Fistula secondary to trauma or radiation\n* Low anal fistula",{"count":55,"type":21},66,[24],"Patients presenting to the outpatient clinic at Kasr Al-Ainy Hospitals with high anal fistula will be assessed according to the inclusion and exclusion criteria. The study purpose will be explained, and informed consent will be obtained from eligible participants. A detailed medical history and routine preoperative assessment will be conducted.\n\nClinical evaluation will include identification of the internal and external openings, assessment of discharge, and continence status using the Jorge-Wexner incontinence score. MRI fistulogram will be performed preoperatively to evaluate the fistula tract and its relation to the sphincter complex.\n\nPatients will be randomly allocated into two equal groups (1:1 ratio) using a computer-generated sequence:\n\nGroup A: Undergo LIFT procedure Group B: Undergo IFOC procedure Both procedures will be performed as per standard surgical techniques. Postoperatively, patients will start oral fluids after 2 hours and resume a normal diet as tolerated. Discharge is planned on the first postoperative day unless otherwise indicated. Follow-up will be conducted at 1 week, 2 weeks, 1 month, and monthly thereafter for at least 6 months to assess healing and detect complications, including recurrence.",[59,27],"Anal Fistula Surgery",[61,62,63],"High anal fistula","IFOC","LIFT","2026-05-20",{"date":66,"type":38},"2026-05-22",{"date":68,"type":38},"2026-04-19",{"date":70,"type":21},"2027-04-01",{"name":44,"class":45}]