[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"high-flow-nasal-canula\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:high-flow-nasal-canula":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,45,77],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":31,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100638571","hfno-flow-rates-and-cerebral-oxygenation-during-deep-sedation-for-cystoscopy-100638571",false,"NCT07630038","HFNO Flow Rates and Cerebral Oxygenation During Deep Sedation for Cystoscopy","Effect of Different Flow Rates of High-Flow Nasal Oxygen on Peripheral and Cerebral Oxygenation and Ventilation During Procedural Sedation for Cystoscopy: A Prospective Randomized Controlled Trial","Inclusion Criteria:\n\n* Age ≥18 years\n* Scheduled to undergo elective cystoscopy under procedural sedation in an operating room setting\n* American Society of Anesthesiologists (ASA) physical status classification I-III\n* Ability to provide written informed consent\n\nExclusion Criteria:\n\n* Known neurological disorders\n* History of ischemic or hemorrhagic stroke\n* Peripheral artery disease\n* Vasculitis\n* Severe heart failure\n* Uncontrolled hypertension\n* Uncontrolled diabetes mellitus\n* Advanced-stage chronic obstructive pulmonary disease\n* Severe anemia (hemoglobin \\\u003C8 g\u002FdL)\n* Skin lesions that could interfere with near-infrared spectroscopy (NIRS) measurements\n* History of head trauma\n* History of cranial surgery\n* Nasal deformity or nasal obstruction",true,"ALL","18 Years",{"count":20,"type":21},200,"ESTIMATED","INTERVENTIONAL",[24],"NA","For Patients and Families\n\nThis study aims to investigate how high-flow oxygen therapy affects oxygen levels, especially brain oxygenation, during cystoscopy procedures performed under sedation. The goal is to improve patient safety and comfort by ensuring better oxygen delivery during the procedure. Different oxygen flow rates will be compared, while patients' breathing, oxygen levels, and vital signs are continuously monitored throughout the procedure. All methods used in the study are consistent with routine anesthesia practices, and patient safety remains the highest priority.\n\nFor Healthcare Professionals\n\nThis prospective randomized controlled study evaluates the effects of different high-flow nasal oxygen (HFNO) flow rates on cerebral oxygenation, peripheral oxygenation, and ventilation parameters in patients undergoing cystoscopy under procedural sedation. The primary aim is to determine the contribution of HFNO to sedation safety and to provide clinical evidence regarding the optimal flow rate. In addition, hypoxemia incidence, airway intervention requirements, hemodynamic variables, and sedation depth are being analyzed.",[27,28,29,30],"Deep Sedation","High Flow Nasal Canula","Cerebral Oxygenation","PSI",[28,27,32,30],"rSO2","NOT_YET_RECRUITING","2026-06-01",{"date":36,"type":37},"2026-06-05","ACTUAL",{"date":34,"type":21},{"date":40,"type":21},"2026-10-01",{"name":42,"class":43},"Firat University","OTHER",1,{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":4,"eligibilityCriteria":51,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":52,"targetDuration":4,"studyType":54,"phases":4,"briefSummary":55,"conditions":56,"keywords":62,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":4},"100640762","effect-of-high-flow-nasal-oxygen-on-laryngoscopic-view-100640762","NCT07575776","Effect of High-Flow Nasal Oxygen on Laryngoscopic View","Effect of Different Flows Using High-Flow Nasal Oxygen (HFNO) on Laryngoscopic View Quality During Videolaryngoscopy","Inclusion Criteria:\n\n* Age ≥18 years\n* Scheduled for endotracheal intubation under general anesthesia\n* Use of videolaryngoscopy\n\nExclusion Criteria:\n\n* Anticipated difficult airway\n* Emergency intubation\n* Contraindications to HFNO\n* Inability to obtain adequate video recording",{"count":53,"type":21},150,"OBSERVATIONAL","This prospective, multicenter observational study aims to evaluate the effect of different flow rates of high-flow nasal oxygen (HFNO) on the quality of the laryngoscopic view during videolaryngoscopy in adult patients undergoing general anesthesia. Each patient will serve as their own control, with repeated measurements obtained at three different HFNO flow settings (0, 40, and 60 L\u002Fmin). The study will assess objective and subjective parameters of glottic visualization using standardized scoring systems.",[28,57,58,59,60,61],"Laryngoscopy","Airway Anesthesia","Airway Complication of Anaesthesia","Difficult Airway","Difficult \u002F Failed Intubation",[63,64,65,66,67],"high flow nasal canula","thrive","difficult airway","airway management","anaesthesia","2026-05-04",{"date":70,"type":37},"2026-05-08",{"date":72,"type":21},"2026-09-01",{"date":74,"type":21},"2027-12-01",{"name":76,"class":43},"Masarykova Nemocnice v Usti nad Labem, Krajska Zdravotni a.s.",{"id":78,"slug":79,"hasResults":11,"nctId":80,"briefTitle":81,"officialTitle":82,"acronym":83,"eligibilityCriteria":84,"healthyVolunteers":11,"sex":17,"minAge":85,"maxAge":86,"enrollmentInfo":87,"targetDuration":4,"studyType":22,"phases":89,"briefSummary":90,"conditions":91,"keywords":4,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":94,"lastUpdatePostDateStruct":95,"startDateStruct":97,"completionDateStruct":99,"leadSponsor":101,"locationsCount":44},"100568626","high-flow-nasal-cannula-for-stabilization-of-extremely-premature-infants-100568626","NCT06683677","High Flow Nasal Cannula for Stabilization of Extremely Premature Infants","High Flow Nasal Cannula is Appropriate Alternative for Stabilization of Extremely Premature Infants: a Prospective Observational Study","SIMPLSAFE2","Inclusion Criteria:\n\n* Preterm infants born between 25+0 and 27+6 gestational weeks\n* Weight above 500 grams\n\nExclusion Criteria:\n\n* Previable rupture of membranes,\n* Congenital malformations previable\n* Acute intrauterine hypoxia.","0 Minutes","2 Minutes",{"count":88,"type":21},60,[24],"A prospective observational study evaluates the safety and efficacy of using High-Flow Nasal Cannula to stabilize extremely preterm infants immediately after birth. Following placental transfusion, high flow nasal cannula at 6-8 l\u002Fmin is administered along with intermittent tactile stimulation. Criteria for switching to other interventions like continuous positive airway pressure or positive pressure ventilation are set for cases of persistent bradycardia or low Saturation of oxygen (SpO2).",[92,93,28],"Premature Infant","Ventilation Therapy","2024-11-12",{"date":96,"type":37},"2024-11-14",{"date":98,"type":21},"2024-12-01",{"date":100,"type":21},"2029-07-01",{"name":102,"class":43},"Charles University, Czech Republic"]