[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"hip-dysplasia\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:hip-dysplasia":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,14,0,[8,41,76,106,136,166,207,230,255,287,315,337,359,380],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":40},"100638438","sii-levels-following-peng-block-in-pediatric-hip-surgery-100638438",false,"NCT07607535","SII Levels Following PENG Block in Pediatric Hip Surgery","Pericapsular Nerve Group Block Mitigates Surgical Stress and Enhances Analgesia in Pediatric Hip Surgery: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Age 3-8 years\n* Scheduled for elective unilateral hip surgery\n* American Society of Anesthesiologists (ASA) physical status I-III\n* Written informed consent from the parent or legal guardian\n\nExclusion Criteria:\n\n* Contraindications to spinal anesthesia or PENG block\n* Infection at the planned needle insertion site\n* Coagulation disorders\n* Chronic immunosuppressive therapy or chronic steroid use\n* Active infection or inflammatory disease\n* Ongoing oncological treatment\n* Known allergy to local anesthetics or study-related medications\n* Conversion to general anesthesia\n* Refusal to participate","ALL","3 Years","8 Years",{"count":20,"type":21},100,"ESTIMATED","INTERVENTIONAL",[24],"NA","This study is a prospective, randomized, double-blind clinical trial. Its aim is to evaluate whether adding a pericapsular nerve group (PENG) block to spinal anesthesia can reduce the inflammatory response after hip surgery in children.\n\nHip surgery in children can cause a strong stress and inflammatory reaction, which may affect pain after surgery, the need for opioid medications, and recovery.\n\nChildren aged 3 to 8 years will be randomly assigned to one of two groups: spinal anesthesia alone or spinal anesthesia combined with a PENG block. The main goal is to compare changes in the Systemic Immune-Inflammation Index (SII), a blood-based marker of inflammation, measured before surgery and 24 hours after surgery.\n\nAdditional outcomes include other inflammatory markers, postoperative pain, opioid use, time to first rescue pain medication, and side effects.",[27],"Hip Dysplasia","NOT_YET_RECRUITING","2026-05-20",{"date":31,"type":32},"2026-05-26","ACTUAL",{"date":34,"type":21},"2026-06-01",{"date":36,"type":21},"2027-08-31",{"name":38,"class":39},"Poznan University of Medical Sciences","OTHER",1,{"id":42,"slug":43,"hasResults":11,"nctId":44,"briefTitle":45,"officialTitle":46,"acronym":47,"eligibilityCriteria":48,"healthyVolunteers":11,"sex":16,"minAge":49,"maxAge":50,"enrollmentInfo":51,"targetDuration":4,"studyType":22,"phases":53,"briefSummary":54,"conditions":55,"keywords":56,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":75},"100423590","exercise-and-patient-education-compared-with-usual-care-in-patients-with-hip-dysplasia-100423590","NCT04795843","Exercise and Patient Education Compared With Usual Care in Patients With Hip Dysplasia","MovetheHip-trial: The Effectiveness of Exercise and Patient Education Compared With Usual Care on Self-reported Pain in Patients With Hip Dysplasia","MovetheHip","Inclusion Criteria:\n\n* Radiographically verified hip dysplasia by a Wiberg's centre edge (CE) angle of 10-25 degrees and an acetabular Index (AI) angle \\>10 degrees\n* Hip and\u002For groin pain as primary pain for at least three months\n* Candidate for periacetabular osteotomy (PAO) but unwilling to undergo PAO, or on a waiting list for surgery (PAO) for 12 months or longer\n* Not candidate for PAO (negative impingement test, BMI \\>25, hip osteoarthritis, age \\>45 years or reduced hip range of motion)\n\nExclusion Criteria:\n\n* Self-reported pain score \\>80 points measured with Copenhagen Hip and Groin outcome score\n* Any major planned surgery (i.e. arthroplastic surgery or discectomy surgery)\n* BMI \\>35\n* Acetabular retroversion defined by crossover sign and posterior wall sign\n* Calvé Legg Perthes or epiphysiolysis\n* Previous pelvic\u002Fhip surgery in index limb\n* Previous pelvic\u002Fhip surgery within the last 2 years in contralateral limb\n* Previous surgery due to herniated disc or spondylodesis\n* Previous arthroplastic surgery in the hip, knee or ankle\n* Physical (pregnancy\u002Ftrauma), neurological, medical or rheumatic conditions severely affecting the hip function\n* Inadequacy in written and spoken Danish, mental illness or other conditions affecting the ability to follow mandatory procedures for participation","18 Years","50 Years",{"count":52,"type":21},200,[24],"This effectiveness trial will investigate if patients with hip dysplasia randomised to exercise and patient education have a different mean change in self-reported pain measured by the Copenhagen Hip and Groin Outcome Score (HAGOS) compared with those randomised to usual care over a six-month follow-up period.\n\nParticipating patients will be allocated to either exercise and patient education or usual care. Alongside this, a health-economic study and a process-evaluation study will be conducted.",[27],[57,58,59,60,61,62,63,64],"Hip Dislocation, Congenital","Exercise","Patient education","Usual care","Effectiveness","Cost-effectiveness","Process evaluation","Periacetabular osteotomy","RECRUITING","2026-05-12",{"date":68,"type":32},"2026-05-15",{"date":70,"type":32},"2021-04-16",{"date":72,"type":21},"2027-12",{"name":74,"class":39},"University of Aarhus",2,{"id":77,"slug":78,"hasResults":11,"nctId":79,"briefTitle":80,"officialTitle":81,"acronym":82,"eligibilityCriteria":83,"healthyVolunteers":84,"sex":16,"minAge":85,"maxAge":50,"enrollmentInfo":86,"targetDuration":4,"studyType":22,"phases":88,"briefSummary":91,"conditions":92,"keywords":93,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":97,"lastUpdatePostDateStruct":98,"startDateStruct":100,"completionDateStruct":102,"leadSponsor":104,"locationsCount":40},"100556043","phase-2-can-plia-reduce-early-post-operative-pain-after-pao-surgery-100556043","NCT06519955","Can PLIA Reduce Early Post-operative Pain After PAO Surgery?","Peri-incisional Local Infiltration to Improve Pain Control After Periacetabular Osteotomy","PILA PAO","Inclusion Criteria:\n\n* Adolescent or young adult diagnosed with hip dysplasia indicated for PAO at University of Iowa Hospital and Clinics.\n\nExclusion Criteria:\n\n* Unable to provide informed consent.\n* Pregnant or breast-feeding individuals\n* Prisoner or ward of the state\n* Allergy or medical contradiction to any of the study medications\n* Patients undergoing femoral osteotomy or surgical hip dislocation with PAO will be excluded",true,"13 Years",{"count":87,"type":21},120,[89,90],"PHASE2","PHASE3","The goal of this clinical trial is to compare different peri-incisional local infiltrative anesthesia (PLIA) methods in patients ages 13 to 50 undergoing a periacetabular osteotomy (PAO). The main questions to answer here are:\n\n1. Does PLIA impact post-operative pain after PAO?\n2. Does PLIA impact pain medication usage as measured by morphine equivalent dosing (MED) after PAO?\n3. Does the timing of PLIA administration impact post-operative pain and MED after PAO? Participants will be asked to complete some surveys; demographics survey, General Self-Efficacy Scale (GSE) and the Pain Resilience Scale. All other information will be gathered from the patients medical chart.\n\nResearchers will compare three groups. 1.) Patients who do not receive PLIA. 2.) Patients who receive PLIA after their incision is closed. 3.) Patients who receive PLIA throughout PAO.",[27],[27,94,95,96],"Periacetabular Osteotomy","PLIA","Peri-Incisional Local Infiltrative Anesthesia","2026-04-14",{"date":99,"type":32},"2026-04-17",{"date":101,"type":32},"2024-10-03",{"date":103,"type":21},"2026-09",{"name":105,"class":39},"Michael C Willey",{"id":107,"slug":108,"hasResults":11,"nctId":109,"briefTitle":110,"officialTitle":110,"acronym":4,"eligibilityCriteria":111,"healthyVolunteers":11,"sex":16,"minAge":112,"maxAge":113,"enrollmentInfo":114,"targetDuration":4,"studyType":22,"phases":116,"briefSummary":117,"conditions":118,"keywords":123,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":97,"lastUpdatePostDateStruct":129,"startDateStruct":131,"completionDateStruct":133,"leadSponsor":135,"locationsCount":40},"100365525","psychosocial-interventions-for-young-adults-with-hip-pain-100365525","NCT04039386","Psychosocial Interventions for Young Adults With Hip Pain","Inclusion Criteria:\n\n* We will enroll young adults (15-39) presenting to one of several physical therapy and orthopedic practices in the state of Iowa for treatment of nonarthritic hip pain.\n* Chief complaint of hip pain or dysfunction, and a diagnosis of a nonarthritic hip condition including labral tear, femoroacetabular impingement (FAI), snapping hip, femoral anteversion or dysplasia.\n\nExclusion Criteria:\n\n* Exclusion criteria will include age \\\u003C15 or \\>40 years\n* Difficulty with written English\n* Treatment for alternative conditions such as trochanteric bursitis, hip dislocation, avascular necrosis or fracture.","15 Years","39 Years",{"count":115,"type":21},150,[24],"Psychosocial conditions are common in young adults with hip pain including depression, anxiety, pain catastrophizing, and narcotic use. The incidence of these conditions is not well defined. Interventions to optimize psychosocial conditions with non-surgical or surgical treatments has not been investigated. The goal of this project is to determine the incidence of psychosocial conditions in the young adult population with hip pain and determine if cognitive based therapy can improve clinical outcomes in these individuals.",[27,119,120,121,122],"Hip Pain Chronic","Hip Osteoarthritis","Hip Arthritis","Psychosocial Problem",[124,125,126,127,128],"Hip Pain","Hip Instability","Hip Impingement","Cognitive Based Therapy","Psychosocial Conditions",{"date":130,"type":32},"2026-04-15",{"date":132,"type":21},"2026-09-01",{"date":134,"type":21},"2028-08-01",{"name":105,"class":39},{"id":137,"slug":138,"hasResults":11,"nctId":139,"briefTitle":140,"officialTitle":141,"acronym":142,"eligibilityCriteria":143,"healthyVolunteers":11,"sex":16,"minAge":49,"maxAge":4,"enrollmentInfo":144,"targetDuration":4,"studyType":22,"phases":146,"briefSummary":147,"conditions":148,"keywords":150,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":157,"lastUpdatePostDateStruct":158,"startDateStruct":160,"completionDateStruct":162,"leadSponsor":164,"locationsCount":4},"100626687","dynamic-lycra-garments-for-hip-dysplasia-feasibility-study-100626687","NCT07438873","Dynamic Lycra Garments for Hip Dysplasia Feasibility Study","Dynamic Lycra Garments to Address Pain and Instability Associated With Hip Dysplasia: a Single Cohort Observational Pilot Study","HIPlycra","Inclusion Criteria:\n\n* 18 years of age or over\n* Clinical diagnosis of Develomental Dysplasia of the Hip (DDH)\n* Clinical diagnosis of hypermobility\n\nExclusion Criteria:\n\n* Under 18 years of age\n* Clinical diagnosis of additional musculoskeletal pathology affecting hips or pelvis",{"count":145,"type":21},12,[24],"Dynamic lycra garments are deployed in rehabilitation and exercise to support unstable areas of the body, enhance sensory feedback to improve movement patterns, reduce fatigue and pain and improve function.\n\n2 case studies have respectively highlighted the effective use of postural correction to reduce hip pain in an adult with acetabular dysplasia while lycra orthoses have reduced pain and improved stability in the hip. Larger scale studies assessing the effect of lycra garments across a clinical population of those presenting with combined hypermobility and hip dysplasia are needed to investigate the extent of generalisable effects.\n\nThe research question underpinning the project is as follows,\"Can the use of dynamic compression shorts during daily activities improve short term treatment outcomes in hip dysplasia patients?\".\n\nThe intention of this single cohort, observational pilot is primarily to establish the feasibility of studying the effect of the garments and assess the justification for further quantitative study, rather than the adjunctive effect of the shorts themselves.\n\nThe investigators are aiming to recruit 8-10 participants who will form a single cohort for observation, with the aim of gathering chiefly qualitative outcomes. This feasibility study is not intended to be blinded.",[27,149],"Hypermobility Syndrome",[151,152,153,154,155,156],"Hypermobility","Orthotic","Hip dysplasia","Physiotherapy","Lycra","Dynamic lycra garments","2026-02-23",{"date":159,"type":32},"2026-02-27",{"date":161,"type":21},"2026-03-03",{"date":163,"type":21},"2027-09-08",{"name":165,"class":39},"Royal National Orthopaedic Hospital NHS Trust",{"id":167,"slug":168,"hasResults":11,"nctId":169,"briefTitle":170,"officialTitle":170,"acronym":4,"eligibilityCriteria":171,"healthyVolunteers":11,"sex":16,"minAge":172,"maxAge":173,"enrollmentInfo":174,"targetDuration":4,"studyType":22,"phases":176,"briefSummary":177,"conditions":178,"keywords":184,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":198,"lastUpdatePostDateStruct":199,"startDateStruct":201,"completionDateStruct":203,"leadSponsor":205,"locationsCount":40},"100579345","early-feasibility-study-of-cartilage-defect-repair-100579345","NCT06823089","Early Feasibility Study of Cartilage Defect Repair","Inclusion Criteria:\n\n1. At least 14 years of age to no older than 64 years of age Subjects 14-21 years of age must have radiographic evidence of epiphyseal closure in the hip joint\n2. BMI \\\u003C 35\n3. Failed at least 6 weeks of conservative treatment (e.g., anti-inflammatory pain medications, physical therapy, injections)\n4. Duration of symptoms consistent with intra-articular disease (i.e., groin, lateral and\u002For posterior hip pain) that have persisted for at least 3 months)\n5. Loss of articular cartilage integrity (\\~1 - 6 cm\\^2 in area) on the femoral head (confirmed by MRI), without an opposing lesion, that can be treated with a single ReNew Hip Implant\n6. Radiographic assessment with joint space width \\> 2 mm (verified by x-ray)\n7. Meets an acceptable preoperative medical clearance and is free of conditions that would pose excessive operative risk, in the opinion of the investigator\n8. Given consent to participate in the study\n9. Able to understand the purpose of the study, his\u002Fher role, and is available for follow-up for the duration of the study:\n\n   1. Subject has signed an IRB (Institutional Review Board) approved Informed Consent Form agreeing to participate in the extension study after the nature, scope, and possible consequences of the study have been explained in an understandable form\n   2. Subject is able to fully understand the purpose of the study, his\u002Fher role as a participant in the study, and plans to be available through five years post-operative follow-up\n\nExclusion Criteria:\n\n1. Current users of nicotine in any form (e.g., cigarettes, e- cigarettes\u002Fvaping, chewing tobacco, nicotine patches, gum, lozenges), or individuals who have discontinued nicotine use less than 30 days prior to screening.\n2. Type 1 or Type 2 Diabetes\n3. Systemic steroid use in the 3 months prior to screening\n4. Coxa plana, coxa magna, or proximal femoral focal deficiency on the femoral head that would result in implant mismatch of the femoral head contour\n5. Any acute or chronic condition that would limit the ability of the patient to participate in the study (e.g., COPD, congestive heart failure),\n6. Bleeding disorders\n7. Current cancer (with the exception of non-melanoma skin cancer)\n8. Pregnancy or planning to become pregnant during the study period\n9. Active infection or sepsis\n10. History of local hip infection\n11. Known metastatic or neoplastic disease\n12. Conditions that may interfere with implant survival or outcomes (e.g., severe dysplasia)\n13. Life expectancy less than 2 years\n14. Intra-articular therapy within 3 months of enrollment\n15. Inadequate bone stock (as determined by SCORE or MORES assessment) to support the device\n16. Femoral head is:\n\n    1. outside of the 46 - 56 mm range in either anteroposterior diameter or lateral diameters or\n    2. an aspherical head deformity that results in contour mismatch of 16a\n17. Moderate to severe renal insufficiency\n18. Emotional or neurological condition that would preempt ability or willingness to participate in the study\n19. Above the knee amputation of the contralateral or ipsilateral leg\n20. Known allergies to the components of the device (polycaprolactone)\n21. Is a prisoner","14 Years","64 Years",{"count":175,"type":21},15,[24],"Any patient aged 14 or older up to 64 years of age with hip disease, resulting in loss of articular cartilage integrity on the femoral head (e.g., femoroacetabular impingement or other structural deformity), has failed conservative care, and is a candidate for surgical intervention to treat.",[179,180,181,182,183,27],"Osteoarthritis, Hip","Femoroacetabular Impingement","Osteonecrosis","Legg-Calvé-Perthes Disease","Osteochondral Lesion",[185,186,187,188,189,190,191,192,193,194,195,196,197],"articular cartilage","hip resurfacing","residual Perthes disease","post-Perthes deformity","femoral head deformity","secondary hip osteoarthritis","hip preservation surgery","adolescent hip deformity","adult hip deformity","avascular necrosis of femoral head","early-stage avascular necrosis","Perthes sequelae","traumatic femoral head lesion","2026-02-12",{"date":200,"type":32},"2026-02-17",{"date":202,"type":32},"2025-11-06",{"date":204,"type":21},"2031-10",{"name":206,"class":39},"Cytex Therapeutics, Inc.",{"id":208,"slug":209,"hasResults":11,"nctId":210,"briefTitle":211,"officialTitle":212,"acronym":4,"eligibilityCriteria":213,"healthyVolunteers":11,"sex":16,"minAge":214,"maxAge":50,"enrollmentInfo":215,"targetDuration":4,"studyType":22,"phases":217,"briefSummary":218,"conditions":219,"keywords":4,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":220,"lastUpdatePostDateStruct":221,"startDateStruct":223,"completionDateStruct":225,"leadSponsor":227,"locationsCount":229},"100322676","periacetabular-osteotomy-with-and-without-arthroscopic-management-of-central-compartment-pathology-100322676","NCT03481010","Periacetabular Osteotomy With and Without Arthroscopic Management of Central Compartment Pathology","Periacetabular Osteotomy With and Without Arthroscopic Management of Central Compartment Pathology: A Multicenter Randomized Controlled Trial","Inclusion Criteria:\n\n* Skeletally mature patient undergoing Bernese periacetabular osteotomy for symptomatic acetabular dysplasia\u002Fhip instability\n* Pre-Operative MRI at 3T and\u002For gadolinium MR arthrogram\n* Age, 16-50 years old\n* Patient capable of giving informed consent\n\nExclusion Criteria:\n\n* Prior hip\u002Fpelvis surgery of any kind on the surgical side\n* Prior hip arthroplasty surgery on either side\n* Radiographic evidence of arthritis (i.e. Tönnis grade =2)\n* Known connective tissue disorder (e.g. Ehlers-Danlos Syndrome, etc.)\n* Known neuromuscular disorder (e.g. Cerebral Palsy, Spina bifida, etc.)\n* Known skeletal dysplasia (e.g. Achondroplasia, Multiple Epiphyseal Dysplasia, etc.)\n* Cognitive impairment that prevents accurate completion of patient-reported outcome questionnaires.\n* Patient unable\u002Funwilling to complete all required follow-up visits\n* Concurrent proximal femoral osteotomy and\u002For surgical hip dislocation","16 Years",{"count":216,"type":21},204,[24],"At present, it is not clear whether performing a hip arthroscopy at the same time as a PAO improves patient outcomes after surgery compared to a PAO alone.\n\nThis research project will randomize patients to receive either a PAO alone, or a PAO and a hip arthroscopy at the same time.",[27],"2025-12-24",{"date":222,"type":32},"2025-12-30",{"date":224,"type":32},"2018-04-04",{"date":226,"type":21},"2030-12-31",{"name":228,"class":39},"Ottawa Hospital Research Institute",7,{"id":231,"slug":232,"hasResults":11,"nctId":233,"briefTitle":234,"officialTitle":235,"acronym":4,"eligibilityCriteria":236,"healthyVolunteers":11,"sex":16,"minAge":4,"maxAge":237,"enrollmentInfo":238,"targetDuration":4,"studyType":22,"phases":240,"briefSummary":241,"conditions":242,"keywords":4,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":246,"lastUpdatePostDateStruct":247,"startDateStruct":249,"completionDateStruct":251,"leadSponsor":253,"locationsCount":40},"100506089","developmental-dysplasia-of-the-hip-observation-vs-bracing-100506089","NCT05869851","Developmental Dysplasia of the Hip: Observation vs. Bracing","Comparison of Brace to Observation in Stable, Radiological Developmental Dysplasia of the Hip: A Multi-centre, International Randomized Controlled Non-inferiority Trial","Inclusion Criteria:\n\n* Patients presenting with radiological dysplasia of a clinically stable hip under three months (12 weeks) of age\n* Radiological dysplasia will be defined as a centred hip with an alpha angle between 43 and 60 degrees and a percent coverage of the femoral head (FHC) greater than 35%, as measured on ultrasound exam\n\nExclusion Criteria:\n\n* Patients presenting with radiological dysplasia older than three months (12 weeks) of age\n* Patients presenting with clinical hip instability (Ortolani or Barlow positive)\n* Patients with known or suspected neuromuscular, collagen, chromosomal or lower-extremity congenital abnormalities or syndromic-associated hip abnormalities\n* Patients who received prior treatment (i.e. Pavlik harness) for DDH","12 Weeks",{"count":239,"type":21},514,[24],"Developmental dysplasia of the hip (DDH) is the most common childhood hip condition. When caught early, bracing is the most frequently used treatment; however, the brace can disrupt important mother-baby bonding time in the newborn period and present challenges to daily living. In babies with mild DDH, some studies have suggested that their hips may improve naturally as they grow and develop. This study will look at whether careful monitoring can be just as good as bracing for babies diagnosed with mild DDH less than 3 months of age, potentially avoiding unnecessary treatment. This will be the first study to look at this question with babies being treated at different hospitals in seven different countries, so the results will make an impact on children and families worldwide.",[243,27,244,245],"Developmental Dysplasia of the Hip","Hip Dysplasia, Congenital","Hip Dysplasia, Developmental","2025-11-19",{"date":248,"type":32},"2025-11-24",{"date":250,"type":32},"2024-04-25",{"date":252,"type":21},"2028-09",{"name":254,"class":39},"University of British Columbia",{"id":256,"slug":257,"hasResults":11,"nctId":258,"briefTitle":259,"officialTitle":260,"acronym":261,"eligibilityCriteria":262,"healthyVolunteers":84,"sex":16,"minAge":263,"maxAge":264,"enrollmentInfo":265,"targetDuration":267,"studyType":268,"phases":4,"briefSummary":269,"conditions":270,"keywords":4,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":246,"lastUpdatePostDateStruct":281,"startDateStruct":282,"completionDateStruct":284,"leadSponsor":286,"locationsCount":40},"100467071","pediatric-orthopaedic-implant-safety--efficacy-100467071","NCT05361980","Pediatric Orthopaedic Implant Safety & Efficacy","Global Pediatric Orthopaedic Implant Safety & Efficacy Clinical Follow-up Program","Global POISE","Inclusion Criteria:\n\n* Patients indicated for the device-specific indication, per physician discretion and as indicated in the device IFU. Off-label use is strongly discouraged; however, any and all on- and off-label indications for use of the products in this program will be collected and stratified accordingly\n* Patients must be able to adhere to the required length of follow-up for the endpoints of each individual product\n* Informed consent\u002Fassent is required\n\nExclusion Criteria:\n\n* Patients with a demonstrated sensitivity to metals\n* Patients with an inability to follow a post-operative regimen","0 Years","25 Years",{"count":266,"type":21},4000,"2 Years","OBSERVATIONAL","Implant devices are important tools - their use is essential across a number of orthopaedic indications, including hip conditions, trauma and limb deformity.\n\nGiven the vital role fixation devices play in maintaining alignment, promoting healthy bone healing and preventing joint degeneration, it is essential to understand the expected lifetime outcomes of these implants, and evaluate their safety and efficacy.\n\nProspective implant efficacy and safety registries are needed to support this endeavour, especially considering new regulatory requirements from the European Union Medical Devices Regulation (EU MDR) in relation to post-market clinical follow-up (PMCF).",[271,272,273,274,275,276,277,27,278,279,280],"Fracture","Lengthening; Leg","Orthopedic Disorder","Deformity of Limb","Deformity; Bone","Implant Breakage","Implant Complication","Pediatric ALL","Hip Disease","Hip Dislocation",{"date":248,"type":32},{"date":283,"type":32},"2022-01-06",{"date":285,"type":21},"2029-12",{"name":254,"class":39},{"id":288,"slug":289,"hasResults":11,"nctId":290,"briefTitle":291,"officialTitle":291,"acronym":4,"eligibilityCriteria":292,"healthyVolunteers":11,"sex":16,"minAge":49,"maxAge":293,"enrollmentInfo":294,"targetDuration":4,"studyType":22,"phases":296,"briefSummary":297,"conditions":298,"keywords":299,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":305,"lastUpdatePostDateStruct":306,"startDateStruct":308,"completionDateStruct":310,"leadSponsor":312,"locationsCount":40},"100598541","shelf-acetabuloplasty-with-3d-printed-implants-as-a-new-treatment-for-symptomatic-adult-hip-dysplasia-100598541","NCT07072832","Shelf Acetabuloplasty With 3D Printed Implants as a New Treatment for Symptomatic Adult Hip Dysplasia","Inclusion Criteria:\n\n* Hip dysplasia based on AP x-ray with a LCEA of \\\u003C25°\n* Groin pain and\u002For gait abnormalities, with no other explanatory hip pathology\n* Aged at least 18 years and maximal 45 years at time of surgery (indicated age for PAO(19))\n* Willing to comply with the study visit schedule during 12 month follow-up\n* Able and willing to provide informed consent\n\nExclusion Criteria:\n\n* Previous acetabular surgery \\>10yr of age\n* Signs of osteoarthritis on x-ray (Tonnis classification \\>1),\n* Body mass index of more than 35\n* Large labral tears visible on non-contrast MRI\n* Pre-consultation known titanium allergy\n* Pre-consultation known medical histories of diseases that per the investigator possibly affect the outcome: neuromuscular disease affecting the stability of the hip, diseases affecting bone ingrowth and fixation strength of the implant like rheumatoid arthritis and metabolic bone diseases, e.g. osteomalacie, osteoporosis, hyperparathyroidism, hypercalcemia.\n* Pre-consultation known pregnant women or women who are planning to become pregnant during the duration of the study.\n* Part of vulnerable population (e.g. Mentally disabled with cognitive impairment or mental disease)\n* Currently participating in another investigational clinical trial.\n* Unable to provide informed consent (e.g. insufficient language skills)","45 Years",{"count":295,"type":21},10,[24],"Hip dysplasia is a common orthopedic condition, defined as an abnormality in the shape, size and orientation of the femoral head, acetabulum or both. The most frequent presentation of hip dysplasia is the maldevelopment of the acetabulum, resulting in insufficient superior coverage of the femoral head, defined as a lateral center-edge angle (Wiberg) of less than 20 degrees. Patients suffer from groin pain, an abnormal gait, decreased strength, and an increased rate of degenerative hip disease.\n\nThe possible treatments affecting the shape of the acetabulum once the patient reaches adolescence are all surgical. The PAO is regarded as the current gold standard in the treatment of symptomatic adult hip dysplasia. The 3-dimensional orientation of the acetabulum is changed with the use of 3 osteotomies around the acetabulum and a refixation in the obtained position. However, the PAO is a difficult operation and is associated with a large number of major complications (up to 37%), and the surgery is associated with a long rehabilitation period.\n\nHence, a strong unmet need exists for an effective but less invasive solution that enhances the quality of life of adult hip dysplasia patients. The treatment gap can be filled with a 3-dimensional (3D) shelf procedure. This custom-made implant (called the 3D-Shelf implant) was developed with the goal to be more predictable in terms of containment and fit than the old autologous shelf-acetabuloplasty, and less invasive and easier to perform than the PAO.\n\nThis study aims to study the safety and evaluate the early performance in terms of the clinical outcomes after implantation of the 3D-Shelf implant in patients with adult hip dysplasia, to show that the 3D-Shelf procedure is safe, has lower complication rates, and shows no inferiority in clinical outcomes compared to the current treatment of a peri-acetabular osteotomy.",[27],[300,301,302,303,304],"Dysplasia","Hip","Adult","Preservation","Shelf","2025-10-01",{"date":307,"type":32},"2025-10-07",{"date":309,"type":32},"2025-08-08",{"date":311,"type":21},"2028-02",{"name":313,"class":314},"Replasia BV","INDUSTRY",{"id":316,"slug":317,"hasResults":11,"nctId":318,"briefTitle":319,"officialTitle":320,"acronym":4,"eligibilityCriteria":321,"healthyVolunteers":11,"sex":16,"minAge":112,"maxAge":322,"enrollmentInfo":323,"targetDuration":4,"studyType":22,"phases":325,"briefSummary":326,"conditions":327,"keywords":4,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":328,"lastUpdatePostDateStruct":329,"startDateStruct":331,"completionDateStruct":333,"leadSponsor":335,"locationsCount":40},"100299668","clinical-trial-of-concomitant-hip-arthroscopy-during-pao-100299668","NCT03181048","Clinical Trial of Concomitant Hip Arthroscopy During PAO","Single-Blind Randomized Clinical Trial of Concomitant Hip Arthroscopy During Periacetabular Osteotomy for the Management of Hip Dysplasia","Inclusion Criteria:\n\n* Diagnosis of hip dysplasia (DDH) electing periacetabular osteotomy (PAO) for treatment\n* Skeletally mature\n* Age 15 - 55\n* Tonnis Grade 0 or 1 osteoarthritis (minimal or no arthritis)\n* Ability to receive a standard of care preoperative (magnetic resonance imaging) MRI arthrogram of the hip\n\nExclusion Criteria:\n\n* Pregnant women\n* Previous surgery about the hip\n* Patients receiving PAO for acetabular retroversion in the absence of DDH\n* Previous hip arthroscopy to address intra-articular pathology","55 Years",{"count":324,"type":21},106,[24],"The study will assess the outcomes of patients treated with concomitant hip arthroscopy at the time of periacetabular osteotomy (PAO) for patients with hip dysplasia compared with patients treated with PAO alone.",[27],"2025-09-04",{"date":330,"type":32},"2025-09-05",{"date":332,"type":32},"2017-08-23",{"date":334,"type":21},"2028-06",{"name":336,"class":39},"Mayo Clinic",{"id":338,"slug":339,"hasResults":11,"nctId":340,"briefTitle":341,"officialTitle":342,"acronym":4,"eligibilityCriteria":343,"healthyVolunteers":11,"sex":16,"minAge":267,"maxAge":214,"enrollmentInfo":344,"targetDuration":4,"studyType":22,"phases":346,"briefSummary":348,"conditions":349,"keywords":4,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":351,"lastUpdatePostDateStruct":352,"startDateStruct":354,"completionDateStruct":356,"leadSponsor":358,"locationsCount":40},"100594718","phase-4-peng-with-lfcb-vs-esp-blocks-for-pediatric-hip-surgery-100594718","NCT07023094","PENG With LFCB vs. ESP Blocks for Pediatric Hip Surgery","Comparison of Analgesic Efficacy of Pericapsular Nerve Group (PENG) Block With Lateral Femoral Cutaneous Nerve Block (LFCB) Versus Lumbar and Sacral Erector Spinae Plane Blocks (L-ESPB and S-ESPB) in Pediatric Hip Surgery: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Pediatric patients aged between 2 and 16 years.\n* Scheduled for elective orthopedic hip surgery, including: Osteotomies and Hip reconstruction surgeries\n* ASA (American Society of Anesthesiologists) physical status classification: I-III.\n* Written informed consent obtained from the patient's legal guardian(s).\n\nExclusion Criteria:\n\n* Known allergy or hypersensitivity to any of the study medications\n* Presence of infection or inflammation at the intended injection site(s) of regional anesthesia.\n* Coagulopathy or bleeding disorders (including patients on anticoagulant therapy) that contraindicate nerve blocks.\n* Neurological disorders or peripheral neuropathies that could influence sensory or motor assessment of the lower limbs.\n* Cognitive impairment or behavioral disorders significantly affecting pain assessment accuracy or cooperation.\n* History of chronic opioid use or known substance abuse.\n* Severe systemic disease or condition compromising patient safety or interfering with study protocol adherence.",{"count":345,"type":21},60,[347],"PHASE4","This randomized controlled trial (RCT) compares the analgesic effectiveness of two regional anesthesia techniques-Pericapsular Nerve Group (PENG) block combined with Lateral Femoral Cutaneous Nerve Block (LFCB) versus Lumbar and Sacral Erector Spinae Plane Blocks (L-ESPB and S-ESPB)-in pediatric patients undergoing hip surgery.",[279,27,350],"Hip Arthropathy","2025-07-08",{"date":353,"type":32},"2025-07-11",{"date":355,"type":32},"2025-06-16",{"date":357,"type":21},"2026-06-30",{"name":38,"class":39},{"id":360,"slug":361,"hasResults":11,"nctId":362,"briefTitle":363,"officialTitle":363,"acronym":4,"eligibilityCriteria":364,"healthyVolunteers":11,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":365,"targetDuration":4,"studyType":268,"phases":4,"briefSummary":367,"conditions":368,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":371,"lastUpdatePostDateStruct":372,"startDateStruct":374,"completionDateStruct":376,"leadSponsor":378,"locationsCount":4},"100589829","long-term-survival-of-tha-after-pelvic-andor-femoral-osteotomy-100589829","NCT06959498","Long-term Survival of THA After Pelvic and\u002For Femoral Osteotomy","Inclusion Criteria:\n\n* patients who underwent THA between 1998 and 2010 and had a prior surgical treatment for hip dysplasia (pelvic, femoral osteotomy, shelf acetabuloplasty or combined osteotomy)\n\nExclusion Criteria:\n\n\\-",{"count":366,"type":21},20,"Analyze the long-term clinical and radiological outcomes of total hip arthroplasty (THA) in patients with hip dysplasia treated by pelvic osteotomy, femoral osteotomy, shelf acetabuloplasty, or a combination of these interventions, performed during childhood or early adulthood. The aim is to understand the impact of these early interventions on THA survival and long-term joint function.",[369,27,370],"Hip Arthropathy Associated With Other Conditions","Survival, Prosthesis","2025-04-28",{"date":373,"type":32},"2025-05-06",{"date":375,"type":21},"2025-05-01",{"date":377,"type":21},"2025-06-01",{"name":379,"class":39},"Central Hospital, Nancy, France",{"id":381,"slug":382,"hasResults":11,"nctId":383,"briefTitle":384,"officialTitle":385,"acronym":4,"eligibilityCriteria":386,"healthyVolunteers":11,"sex":16,"minAge":4,"maxAge":49,"enrollmentInfo":387,"targetDuration":4,"studyType":22,"phases":389,"briefSummary":390,"conditions":391,"keywords":4,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":394,"lastUpdatePostDateStruct":395,"startDateStruct":397,"completionDateStruct":399,"leadSponsor":401,"locationsCount":403},"100530668","phase-4-pain-injection-versus-epidural-anesthesia-for-hip-surgery-in-pediatric-patients-with-cerebral-palsy-100530668","NCT06189781","Pain Injection Versus Epidural Anesthesia for Hip Surgery in Pediatric Patients With Cerebral Palsy","Peri-operative Use of a Pain Injection Versus Epidural in Pediatric Patients With Cerebral Palsy","Inclusion Criteria:\n\n* under 18 years old\n* diagnosis of cerebral palsy or similar neuromuscular disease\n* undergoing uni- or bilateral proximal femoral osteotomy\n\nExclusion Criteria:\n\n* ongoing preoperative opioid use\n* history of allergic reaction to any component of the pain injection\n* history of adverse reaction to epidural anesthesia",{"count":388,"type":21},90,[347],"Pain management in pediatric patients presents a difficult challenge. Unlike adults, pediatric patients often cannot communicate their pain management needs clearly. This is especially true in patients with cerebral palsy (CP), who often have concomitant developmental delay, intellectual disability and verbal limitations. Current literature indicates pain as a common experience for children with CP but has been understudied in this population. Moreover, inadequate post-operative pain control can result in negative physiologic and psychological complications and lead to poor surgical outcomes. Currently, perioperative pain management following orthopaedic procedures in pediatric patients follows traditional protocols that rely on the administration of opioid medications despite their known adverse side effects including nausea, vomiting, itching, constipation, urinary retention, confusion, and respiratory depression.\n\nEpidural anesthesia is a key modality in traditional pain management for pediatric patients with CP given its proven efficacy in decreasing pain and managing spasticity. Yet, administering epidural anesthesia in this patient population poses several risks including damage to preexisting intrathecal baclofen pumps, iatrogenic infection, and technically demanding insertion given high rates of concomitant neuromuscular scoliosis. Alternatively, multimodal analgesic injections theoretically offer an efficacious adjunct to traditional pain management protocols with a lower risk profile. Preliminary data from our study group's pilot randomized control trial comparing the safety and efficacy of a multimodal surgical site injection to placebo showed decreased pain scores and narcotic consumption postoperatively in this patient population. Based on these promising results, the objective of this randomized control trial is to evaluate the efficacy of a multimodal surgical site injection compared to epidural anesthesia for postoperative pain control following operative management of hip dysplasia in pediatric patients with CP.",[392,27,393],"Cerebral Palsy","Pain, Postoperative","2024-06-07",{"date":396,"type":32},"2024-06-11",{"date":398,"type":32},"2023-12-01",{"date":400,"type":21},"2027-06-30",{"name":402,"class":39},"University of California, Los Angeles",4]