[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"hip-fracture-surgeries\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:hip-fracture-surgeries":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,9,0,[8,47,70,96,123,165,191,214,238],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100619855","comparison-of-femoral-nerve-block-and-combined-peng-plus-femoral-nerve-block-in-geriatric-hip-surgery-100619855",false,"NCT07350044","Comparison of Femoral Nerve Block and Combined PENG Plus Femoral Nerve Block in Geriatric Hip Surgery","A Prospective Randomized Controlled Trial Comparing Femoral Nerve Block and Combined Pericapsular Nerve Group (PENG) Plus Femoral Nerve Block for Perioperative Analgesia in Geriatric Hip Fracture Surgery","PENG-FEM","Inclusion Criteria:\n\n* Age 65 years and older,\n* Patients scheduled for surgery due to hip fracture,\n* American Society of Anesthesiologists (ASA) physical status I-III,\n* Body mass index between 18 and 40 kg\u002Fm²,\n* Preoperative fasting duration of approximately 8 hours,\n* Planned spinal anesthesia,\n* Ability to provide written informed consent.\n\nExclusion Criteria:\n\n* Age below 65 years,\n* Refusal to participate in the study,\n* Severe cognitive impairment, dementia, or Alzheimer's disease,\n* ASA physical status IV or higher,\n* Body mass index \\> 40 kg\u002Fm²,\n* Failed spinal anesthesia or conversion to general anesthesia,\n* Revision hip surgery,\n* Multiple trauma patients,\n* Old hip fractures (\\>3 weeks),\n* Active malignancy receiving chemotherapy or radiotherapy,\n* Active infection requiring antibiotic treatment (except prophylaxis),\n* Contraindications to regional anesthesia techniques,\n* Chronic steroid or immunosuppressive therapy,\n* Use of anti-inflammatory drugs,\n* Non-fasted patients,\n* Allergy or intolerance to local anesthetics, paracetamol, tramadol, or other opioids.","ALL","65 Years",{"count":20,"type":21},68,"ESTIMATED","INTERVENTIONAL",[24],"NA","Hip fracture surgery in geriatric patients is frequently associated with severe perioperative pain, which may complicate positioning for spinal anesthesia and increase perioperative opioid requirements. Regional analgesic techniques are commonly used to improve patient comfort and reduce opioid consumption in this vulnerable population. The femoral nerve block is a well-established method for analgesia in hip surgery, while the pericapsular nerve group (PENG) block has emerged as a novel technique targeting articular branches of the hip joint with potential advantages in pain control.\n\nThis prospective randomized controlled trial aims to compare the analgesic efficacy of femoral nerve block alone versus a combined pericapsular nerve group (PENG) plus femoral nerve block in geriatric patients undergoing hip fracture surgery under spinal anesthesia. The primary outcomes include perioperative pain intensity, opioid consumption within the first 24 hours postoperatively, and the need for additional analgesia during positioning for spinal anesthesia. Secondary outcomes include spinal anesthesia procedure duration, time to sensory block onset, time to first postoperative opioid requirement, and perioperative hemodynamic parameters.\n\nThe results of this study are expected to clarify whether the addition of the PENG block to femoral nerve block provides superior perioperative analgesia and improved patient comfort compared with femoral nerve block alone in geriatric hip fracture surgery.",[27,28],"PENG Block","Hip Fracture Surgeries",[30,31,28,32,33],"PENG block","Femoral block","Pain","Opioid","RECRUITING","2026-03-23",{"date":37,"type":38},"2026-03-25","ACTUAL",{"date":40,"type":38},"2026-01-15",{"date":42,"type":21},"2026-06-01",{"name":44,"class":45},"Ankara City Hospital Bilkent","OTHER",1,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":4,"eligibilityCriteria":53,"healthyVolunteers":11,"sex":17,"minAge":54,"maxAge":4,"enrollmentInfo":55,"targetDuration":4,"studyType":22,"phases":57,"briefSummary":58,"conditions":59,"keywords":4,"overallStatus":60,"whyStopped":4,"lastUpdateSubmitDate":61,"lastUpdatePostDateStruct":62,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":4},"100626544","the-effect-of-abdomnal-massage-and-warm-water-consumpton-on-postoperatve-constpaton-development-and-qualty-of-recovery-in-patents-undergong-hp-fractures-surgery-100626544","NCT07437014","The Effect of Abdomınal Massage and Warm Water Consumptıon on Postoperatıve Constıpatıon Development and Qualıty of Recovery in Patıents Undergoıng Hıp Fractures Surgery","The Effect of Abdomınal Massage and Warm Water Consumptıon on Postoperatıve Constıpatıon Development and Qualıty of Recovery in Patıents Undergoıng Hıp Fractures Surgery: A Randomızed Comparatıve Study","Inclusion Criteria:\n\n* Being 18 years of age or older\n* Agreeing to participate in the study\n* Undergoing open surgical treatment due to a hip fracture classified as 31A, 31B, or 31C according to the AO\u002FOTA classification\n* Initiation of postoperative oral feeding\n\nExclusion Criteria:\n\n* Communication problems (speech and hearing impairments)\n* Neurological and psychiatric problems such as Alzheimer's or dementia\n* Problems preventing abdominal massage (surgery, wound site)\n* Regular laxative use before surgery\n* Previous colon surgery - physiological and structural abnormalities in the anal region that may hinder bowel movements\n* Use of medications that reduce bowel motility before surgery (antipsychotics, antidepressants, etc.)\n* Diagnosis of chronic constipation made by a physician before surgery\n* Difficulty transitioning to oral feeding and inability to eat orally\n* Multiple traumas affecting mobilization in addition to a hip fracture\n* Surgery for hip fracture performed using a minimally invasive method","18 Years",{"count":56,"type":21},81,[24],"There is a need for studies investigating the effects of abdominal massage and warm water consumption on the development of postoperative constipation and quality of recovery in patients who have undergone hip fracture surgery. The aim of the study is to investigate the effects of abdominal massage and warm water consumption on the development of postoperative constipation quality of recovery in patients who have undergone hip fracture surgery. The study will be conducted as a prospective, parallel, three-group (1:1:1) randomized controlled trial to determine the effect of abdominal massage alone versus standard care in preventing the development of postoperative constipation in patients who underwent surgery for hip fracture. The following instruments will be used to collect study data: \"Patient Demographic Information Form\", \"Constipation Risk Assessment Scale\" for determining the constipation risk group and for randomization, \"Bristol Stool Scale\" for determining the type of constipation, \"Constipation Assessment Scale\" for determining the severity of constipation, and \"Quality of Recovery-40 Questionnaire\". For data analysis, parametric (Independent Samples T-Test, ANOVA) or non-parametric tests (Mann-Whitney U, Kruskal-Wallis H) will be used for pairwise and multiple group comparisons, depending on the distribution of the data. The Chi-Square test will be used for categorical data, and logistic regression analysis will be performed to determine the effect of continuous variables obtained from constipation development status and patient follow-up on the development or absence of constipation.",[28],"NOT_YET_RECRUITING","2026-03-01",{"date":63,"type":38},"2026-03-04",{"date":65,"type":21},"2026-02-20",{"date":67,"type":21},"2028-03-01",{"name":69,"class":45},"Hacettepe University",{"id":71,"slug":72,"hasResults":11,"nctId":73,"briefTitle":74,"officialTitle":75,"acronym":4,"eligibilityCriteria":76,"healthyVolunteers":11,"sex":17,"minAge":77,"maxAge":78,"enrollmentInfo":79,"targetDuration":4,"studyType":22,"phases":81,"briefSummary":82,"conditions":83,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":46},"100626983","sacral-espb-vs-peng-block-for-hip-hemiarthroplasty-analgesia-100626983","NCT07442721","Sacral ESPB vs. PENG Block for Hip Hemiarthroplasty Analgesia","Sacral Erector Spinae Plane Block Versus Pericapsular Nerve Group Block For Analgesia In Hip Hemi Arthroplasty: A Randomized Comparative Study","Inclusion Criteria:\n\n* Patients with ages from 50 to 90 years of either gender, with diagnosis of intracapsular neck of femur fracture scheduled for elective hip hemiarthroplasty • Patients with an American Society of Anesthesiologists (ASA) physical status I to III.\n\nExclusion Criteria:\n\n* • Patient refusal.\n\n  * Allergy to local anesthetics and patient with infection at the injection site of block\n  * Patient with contraindication to spinal anesthesia.\n  * Coagulopathy as INR≥1.5 or platelets ≤80\\*103 \u002F microliter)\n  * Patients with body mass index\\>35 kg \u002F m2\n  * Patients with peripheral neuropathy or diabetic neuropathy\n  * Patients receiving opioids for chronic analgesic therapy (cancer, addiction).\n  * Cognitive impairment preventing pain scoring.\n  * Chronic renal failure requiring dose modification.\n  * Bilateral hip fracture or previous ipsilateral hip surgery","50 Years","90 Years",{"count":80,"type":21},80,[24],"Sacral erector spinae plane block(S-ESPB) has been recently described. Case reports are showing that it is useful in various types of surgery. In case presentations, it has been reported as effective in providing analgesia in the posterior branches of the sacral nerves in pilonidal sinus surgery, in the treatment of radicular pain at the L5 - S1 level, after a sex reassignment operation and hypospadias surgery, and its use in combination with lumbar ESPB for analgesia was reported after hip prosthesis surgery . Described in 2018, pericapsular nerve group (PENG) block selectively targets the articular branches of the femoral and accessory obturator nerves thereby providing potential motorsparing analgesia for hip surgery\n\n. Recent studies found that PENG block targets the articular branches of the femoral and accessory obturator nerves, only anesthetizes the anterior hip joint sparing posterior part , as well as there was a motor impairment after block which is from local anesthetic (LA) diffusion to the femoral nerve\n\n. Motor-sparing regional anesthesia techniques have emerged as a safer alternative, balancing effective pain relief with the preservation of quadriceps function . These techniques align with Enhanced Recovery After Surgery (ERAS) protocols, which emphasize multimodal pain control, opioid minimization, and early mobility to reduce complications such as venous thromboembolism (VTE) and postoperative pneumonia\n\n.",[84,28,85,86],"Hip Arthroplasty","Femoral Neck Fractures","Postoperative Pain","2026-02-28",{"date":89,"type":38},"2026-03-03",{"date":91,"type":38},"2026-02-01",{"date":93,"type":21},"2027-08-01",{"name":95,"class":45},"Fayoum University Hospital",{"id":97,"slug":98,"hasResults":11,"nctId":99,"briefTitle":100,"officialTitle":100,"acronym":101,"eligibilityCriteria":102,"healthyVolunteers":11,"sex":17,"minAge":103,"maxAge":4,"enrollmentInfo":104,"targetDuration":4,"studyType":22,"phases":106,"briefSummary":107,"conditions":108,"keywords":111,"overallStatus":60,"whyStopped":4,"lastUpdateSubmitDate":114,"lastUpdatePostDateStruct":115,"startDateStruct":117,"completionDateStruct":119,"leadSponsor":121,"locationsCount":46},"100626001","impact-of-pre-operative-sarcopenia-on-functional-recovery-after-hip-arthroplasty-in-older-adults-100626001","NCT07429955","Impact of Pre-operative Sarcopenia on Functional Recovery After Hip Arthroplasty in Older Adults","HIP-REGEN","Inclusion Criteria:\n\n\\- Elderly subjects undergoing surgical hip replacement for fracture of the upper end of the femur or severe hip osteoarthritis.\n\nExclusion Criteria for both groups :\n\n* Contraindications to MRI : pacemaker, metallic implants.\n* Presence of a lower-limb prosthesis on the contralateral side to the surgery that may interfere with quadriceps mass measurements.\n* Progressive high-grade neoplasia.\n* Documented major cognitive disorders\n* Under legal protection measures (guardianship, conservatorship, or curatorship).\n* Subjects not affiliated with or not covered by a social security system.\n* Participation in another ongoing study with an active exclusion period.\n\nExclusion criteria - Fracture group :\n\n* Fracture with a suspicion of underlying neoplasia.\n* Placement of a lower-limb prosthesis on the surgical side within the last 12 months.\n* Inability to walk with or without human\u002Ftechnical assistance prior to fracture.\n\nExclusion criteria - Hip osteoarthritis group :\n\n\\- Active inflammatory joint disease (rheumatoid arthritis, spondyloarthritis).","75 Years",{"count":105,"type":21},20,[24],"This single-centre, exploratory study at Montpellier University Hospital will investigate whether having low muscle mass and strength before hip-replacement surgery, a condition called sarcopenia, impact the return to everyday independence in people aged 75 years or older. About 20 volunteers, scheduled for surgery because of a recent femoral-neck fracture or severe arthritis that no longer responds to usual care, will give consent, answer brief health questionnaires, attempt simple walking and chair-rise tests if possible, and provide a small blood sample. While they are already under anaesthesia for their planned operation, the surgical team will take a tiny muscle sample through the same incision, so no extra cuts are needed. During the hospital stay or shortly after discharge, each participant will have a painless MRI scan of the thigh muscles and a very-low-dose bone scan (DXA) to measure muscle and bone health. The research team will then telephone participants at 3 and 6 months to ask about daily activities, walking ability, and any complications. The study lasts about six months for each person and does not alter their usual medical or rehabilitation care. Potential benefits include close follow-up, personalised feedback on muscle and bone results, and helping doctors learn whether pre-surgery muscle weakness predicts slower recovery-information that could guide future, more personalised exercise and nutrition programs. Extra study procedures carry only minimal risks: a routine blood draw, scans with none (MRI) or very little (DXA) radiation, and a muscle biopsy taken during surgery. Taking part is entirely voluntary, and participants may withdraw at any time without affecting their current or future care. The whole project will run for 18 months.",[109,110,28],"Sarcopenia in Elderly","Osteoarthritis (OA)",[109,110,28,112,113],"Functional Recovery","Rehabilitation","2026-02-17",{"date":116,"type":38},"2026-02-24",{"date":118,"type":21},"2026-02",{"date":120,"type":21},"2027-08",{"name":122,"class":45},"University Hospital, Montpellier",{"id":124,"slug":125,"hasResults":11,"nctId":126,"briefTitle":127,"officialTitle":128,"acronym":129,"eligibilityCriteria":130,"healthyVolunteers":11,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":131,"targetDuration":4,"studyType":133,"phases":4,"briefSummary":134,"conditions":135,"keywords":144,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":155,"lastUpdatePostDateStruct":156,"startDateStruct":158,"completionDateStruct":160,"leadSponsor":162,"locationsCount":164},"100616764","hip-fracture-surgery-timing-and-blood-transfusion-risk-in-patients-on-doacs-100616764","NCT07309848","Hip Fracture Surgery Timing and Blood Transfusion Risk in Patients on DOACs","Blood Transfusion Risk After Early vs. Delayed Surgery in Hip Fracture Patients on Direct Oral Anticoagulants: A Natural Experiment","OPTIMIZEDOAC","Inclusion Criteria:\n\n* Isolated hip fracture classified as AO\u002FOTA 31A or 31B requiring surgical intervention.\n* Current DOAC use with the last dose taken ≤24 hours before emergency department (ED) presentation\n\nExclusion Criteria:\n\n* Pathologic or periprosthetic hip fractures.\n* Fracture sustained \\>24 hours before ED presentation.\n* Inter-hospital transfer.\n* Hematologic disorders (e.g., thalassemia, sickle cell disease, aplastic anemia, myelodysplastic syndromes, leukemia).\n* Use of a non-EMA-approved DOAC (e.g., betrixaban).",{"count":132,"type":21},374,"OBSERVATIONAL","This study looks at patients with hip fractures who are taking direct oral anticoagulants (DOACs), a type of blood thinner. In many hospitals, surgery for these patients is delayed because of concerns about bleeding, but waiting longer can also increase risks such as complications and longer hospital stays. The purpose of this study is to find out whether operating within 24 hours is as safe as delaying surgery beyond 24 hours. Specifically, the investigators want to know if early surgery does not lead to a higher need for blood transfusions compared to delayed surgery.",[136,28,137,138,139,140,141,142,143],"Blood Transfusion","Geriatric","Bleeding Complications","Bleeding as Surgical Complication (Treatment)","Bleeding","Blood Transfusions","Blood Transfusion Complication","Direct Oral Anticoagulants (DOACs)",[145,146,147,148,149,150,151,152,153,154],"natural experiment","doac","direct oral anticoagulant","hip fracture","geriatric","surgery","bleeding","blood transfusion","early","delayed","2025-12-15",{"date":157,"type":38},"2025-12-30",{"date":159,"type":38},"2025-11-01",{"date":161,"type":21},"2027-12-31",{"name":163,"class":45},"St. Antonius Hospital",7,{"id":166,"slug":167,"hasResults":11,"nctId":168,"briefTitle":169,"officialTitle":170,"acronym":4,"eligibilityCriteria":171,"healthyVolunteers":11,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":172,"targetDuration":4,"studyType":22,"phases":174,"briefSummary":175,"conditions":176,"keywords":178,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":182,"lastUpdatePostDateStruct":183,"startDateStruct":185,"completionDateStruct":187,"leadSponsor":189,"locationsCount":46},"100595635","self-guided-immersive-virtual-reality-versus-mannequin-based-simulators-to-teach-the-ultrasound-guided-supra-inguinal-fascia-iliaca-block-100595635","NCT07035015","Self-Guided Immersive Virtual Reality Versus Mannequin-based Simulators to Teach the Ultrasound-Guided Supra-Inguinal Fascia Iliaca Block","Self-Guided Immersive Virtual Reality Versus Mannequin-based Simulators to Teach the Ultrasound-Guided Supra-Inguinal Fascia Iliaca Block: A Non-inferiority Randomized Controlled Study","Inclusion Criteria:\n\n* Staff and trainees from anesthesiology, emergency medicine, and orthopedic surgery. All participants will be locally recruited within The Ottawa Hospital",{"count":173,"type":21},36,[24],"This research project aims to see if using immersive virtual reality (iVR) is as good as using traditional mannequins to teach medical staff how to perform a specific nerve block called an ultrasound-guided supra-inguinal fascia iliaca (SIFI) block. This nerve block is important for managing pain in patients with hip fractures, as it can improve recovery, shorten hospital stays, and reduce healthcare costs. Currently, not enough eligible hip fracture patients receive these beneficial nerve blocks.\n\nThe study will recruit 36 staff and trainees from anesthesiology, emergency medicine, and orthopedic surgery at The Ottawa Hospital. Participants will be randomly assigned to one of two groups. One group will learn the SIFI block using a newly developed iVR simulator that uses real human anatomy and allows for practice of needling and injecting. The other group will use traditional mannequin-based simulators.\n\nAll participants will receive educational materials and videos before their training. Their skills will be tested before the training, immediately after, and again one month later using a hybrid simulator (a combination of a mannequin and a soft embalmed human cadaver part). The main thing being measured is their skill level using a standardized scoring system. The study also wants to see if the iVR simulator is well-tolerated by users. The overall goal is to improve care for hip fracture patients through better, more accessible training for medical staff.",[177,28],"Nerve Block",[179,180,181],"Virtual Reality","Ultrasound-guided Regional Anesthesia","Simulation","2025-06-15",{"date":184,"type":38},"2025-06-24",{"date":186,"type":38},"2025-06-01",{"date":188,"type":21},"2025-11",{"name":190,"class":45},"The Ottawa Hospital",{"id":192,"slug":193,"hasResults":11,"nctId":194,"briefTitle":195,"officialTitle":196,"acronym":4,"eligibilityCriteria":197,"healthyVolunteers":11,"sex":17,"minAge":54,"maxAge":198,"enrollmentInfo":199,"targetDuration":4,"studyType":133,"phases":4,"briefSummary":201,"conditions":202,"keywords":4,"overallStatus":60,"whyStopped":4,"lastUpdateSubmitDate":205,"lastUpdatePostDateStruct":206,"startDateStruct":208,"completionDateStruct":210,"leadSponsor":212,"locationsCount":4},"100594822","comparison-of-cardiovascular-risks-between-hip-fracture-surgery-with-continued-daptdual-antiplatelet-therapy--within-6-weeks-vs-after-6-weeks-post-pcipercutaneous-coronary-intervention-a-prospective-observational-cohort-study-100594822","NCT07024446","Comparison of Cardiovascular Risks Between Hip Fracture Surgery With Continued DAPT（Dual Antiplatelet Therapy ） Within 6 Weeks vs After 6 Weeks Post-PCI（Percutaneous Coronary Intervention）: A Prospective Observational Cohort Study","Comparison of Cardiovascular Risks Between Hip Fracture Surgery With Continued （Dual Antiplatelet Therapy ） Within 6 Weeks vs After 6 Weeks Post-（Percutaneous Coronary Intervention）: A Prospective Observational Cohort Study","Inclusion Criteria:\n\nNormal hs-cTnI levels prior to NCS BMI 20-28 kg\u002Fm² Post-PCI procedure, currently on regular DAPT therapy Complete PCI procedural documentation (date, quantity, stent type) Mentally sound, capable of normal communication\n\nExclusion Criteria:\n\nAbnormal hs-cTnI before NCS; Accompanied by dysfunction of other organs History of other major surgeries Risk factors for stent thrombosis (age \\>79 years, impaired left ventricular function, stent implantation due to acute coronary syndrome, multiple stents, diabetes, renal insufficiency with creatinine \\>1.5 mg\u002Fdl) Abnormal coagulation function Local anesthesia surgery Inability to cooperate","79 Years",{"count":200,"type":21},50,"Percutaneous coronary intervention (PCI) is commonly used to treat stable ischemic heart disease. Among patients, 7.5% require surgical treatment, and up to 20% may need noncardiac surgery (NCS) within two years.\n\nCompared to patients without coronary stents, those requiring NCS shortly after PCI face an increased risk of perioperative major adverse cardiac and cerebrovascular events (MACCE), primarily manifested as thrombotic and bleeding events. Guidelines recommend 6-12 months of dual antiplatelet therapy (DAPT) post-PCI to prevent stent thrombosis, which is associated with an elevated risk of perioperative bleeding during NCS. Multiple retrospective studies suggest that the incidence of MACCE decreases as the interval between PCI and NCS lengthens, reaching a risk level similar to non-PCI patients after 12 months. However, other studies indicate that the risk in patients with similar PCI-NCS intervals correlates more with surgical complexity and urgency. Guidelines advise adequate antiplatelet therapy post-PCI to prevent stent thrombosis and recommend avoiding elective surgery within 4-6 weeks after PCI, contingent on bleeding and thrombotic risk assessments.\n\nMany post-PCI patients facing NCS option to delay surgery after weighing the risks of discontinuing antiplatelet therapy versus postponement, which not only reduces quality of life but also increases the risks associated with delayed surgery. Additionally, retrospective studies have found that in unavoidable emergency or time-sensitive surgeries, the heightened perioperative cardiovascular risk is primarily due to the underlying surgical condition affecting organ function, rather than the PCI-NCS interval or antiplatelet therapy discontinuation.\n\nRecent advancements in minimally invasive surgical techniques have reduced trauma and bleeding, leading to broader indications for surgery in patients on anticoagulant or antiplatelet therapy. The widespread use of newer-generation drug-eluting stents (DES) with advanced antiproliferative drugs has further lowered stent thrombosis rates. Moreover, refined PCI techniques minimize vascular injury during stent placement, reducing the likelihood of extra-stent restenosis. From an anesthesiology perspective, concerns for post-PCI surgical patients extend beyond bleeding risks to whether cardiac function can withstand perioperative hemodynamic changes. As surgical and anesthetic techniques evolve, traditional single-method anesthesia is increasingly replaced by combined techniques that ensure adequate analgesia while minimizing hemodynamic disturbances, maintaining oxygen supply-demand balance, and reducing ischemic and bleeding events.\n\nHip fractures in elderly patients, often termed the \"last fracture in life,\" carry high surgical and anesthetic risks for those with coronary artery disease. While PCI addresses coronary stenosis, the use or discontinuation of antiplatelet therapy exposes patients to bleeding and ischemic risks. The optimal timing for hip fracture surgery is within 48 hours; delays may lead to malunion, prolonged bedrest complications (e.g., pressure sores, pneumonia), and increased deep vein thrombosis risk. Modern hip fracture surgeries (e.g., internal fixation, hip replacement, Proximal femoral nail antirotation internal fixation) are well-established, with reduced bleeding and faster recovery, making it feasible to perform surgery without interrupting antiplatelet therapy.\n\nExisting research primarily consists of retrospective analyses of cardiovascular risk prediction in post-PCI patients undergoing NCS, with no recent prospective studies. Guideline recommendations on PCI-NCS intervals remain unchanged since 2016. Consequently, many PCI patients must delay surgery, enduring unpredictable risks and diminished quality of life.\n\nThis study aims to prospectively observe the incidence of MACCE in hip fracture surgery performed within six weeks post-PCI without discontinuing DAPT. The findings may provide evidence for the feasibility of early post-PCI surgery, offer clinicians and patients safer antithrombotic strategies, and present a new option to improve patient quality of life.",[203,204,28],"PCI Patients","DAPT(Dual Antiplatelet Therapy)","2025-06-09",{"date":207,"type":38},"2025-06-17",{"date":209,"type":21},"2025-07-01",{"date":211,"type":21},"2027-07-01",{"name":213,"class":45},"Fujian Medical University Union Hospital",{"id":215,"slug":216,"hasResults":11,"nctId":217,"briefTitle":218,"officialTitle":219,"acronym":4,"eligibilityCriteria":220,"healthyVolunteers":11,"sex":17,"minAge":221,"maxAge":222,"enrollmentInfo":223,"targetDuration":4,"studyType":22,"phases":225,"briefSummary":226,"conditions":227,"keywords":228,"overallStatus":60,"whyStopped":4,"lastUpdateSubmitDate":231,"lastUpdatePostDateStruct":232,"startDateStruct":234,"completionDateStruct":235,"leadSponsor":236,"locationsCount":46},"100593222","preoperative-analgesia-the-effectiveness-of-the-peng-block-in-patients-with-hip-fractures-100593222","NCT07003633","Preoperative Analgesia: The Effectiveness of the PENG Block in Patients With Hip Fractures","Preoperative Analgesia: The Effect of the Pericapsular Nerve Group (PENG) Block Administered Preoperatively in Patients With Hip Fractures on Preoperative Analgesic Efficacy, Early Postoperative Discharge, Mortality, and Morbidity.","Inclusion Criteria:\n\n* Patients undergoing hip farcture surgery\n\nExclusion Criteria:\n\n* Chronic analgesics consumption\n* Patients contraindicated for neuraxial anesthesia\n* Alcohol and drug addiction\n* Allergies to local anesthetics and opioids\n* Patients who refuses to participate in the study","45 Years","95 Years",{"count":224,"type":21},60,[24],"The aim is to provide effective preoperative analgesia in patients undergoing surgical procedures due to hip fractures by administering a pericapsular nerve group (PENG) block under ultrasound guidance. This approach seeks to increase patient satisfaction, reduce analgesic requirements, enable earlier discharge, and decrease morbidity and mortality.",[28],[229,30,230],"Analgesia","Hip Fracture","2025-05-26",{"date":233,"type":38},"2025-06-04",{"date":186,"type":21},{"date":42,"type":21},{"name":237,"class":45},"Sakarya University",{"id":239,"slug":240,"hasResults":11,"nctId":241,"briefTitle":242,"officialTitle":243,"acronym":4,"eligibilityCriteria":244,"healthyVolunteers":11,"sex":17,"minAge":54,"maxAge":18,"enrollmentInfo":245,"targetDuration":4,"studyType":133,"phases":4,"briefSummary":246,"conditions":247,"keywords":4,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":250,"lastUpdatePostDateStruct":251,"startDateStruct":253,"completionDateStruct":254,"leadSponsor":255,"locationsCount":46},"100581597","iliopsoas-nerve-block-and-femoral-nerve-block-in-hip-fracture-surgeries-100581597","NCT06852378","Iliopsoas Nerve Block and Femoral Nerve Block in Hip Fracture Surgeries","Comparison Between Iliopsoas Nerve Block and Femoral Nerve Block in Hip Fracture Surgeries","Inclusion Criteria:\n\n* Age from 18 to 65 years.\n* Both sexes.\n* American Society of Anesthesiologists (ASA) physical status I and II.\n* Patients who are scheduled for elective surgical correction of hip fracture either through open fracture internal fixation (ORIF), partial hip arthroplasty or total hip arthroplasty.\n\nExclusion Criteria:\n\n* Refusal to participate.\n* Coagulopathy.\n* Patients with a history of drug allergies to study drugs.\n* Inability to cooperate.",{"count":80,"type":21},"This study aims to compare iliopsoas nerve Block (IPB) to femoral nerve block (FNB) regarding pain control, patient satisfaction, and early ambulation in patients undergoing hip fracture surgeries",[248,249,28],"Iliopsoas Nerve Block","Femoral Nerve Block","2025-03-01",{"date":252,"type":38},"2025-03-04",{"date":250,"type":38},{"date":91,"type":21},{"name":256,"class":45},"Ain Shams University"]