[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"hip-replacement-total\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:hip-replacement-total":32},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,51,82,111],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":34,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":50},"100579224","comparison-of-pain-relief-methods-for-hip-surgery-a-study-on-two-different-nerve-block-techniques-100579224",false,"NCT06821516","Comparison of Pain Relief Methods for Hip Surgery: A Study on Two Different Nerve Block Techniques","Comparison of Analgesic Effectiveness Between Pericapsular Nerve Group (PENG) Block and Lumbar Erector Spinae Plane Block in Patients Undergoing Total Hip Arthroplasty With Spinal Anesthesia: a Randomized Controlled Trial","Inclusion Criteria:\n\n* Voluntary willingness to participate in the study.\n* Patients who will undergo Total Hip Arthroplasty surgery.\n* Patients aged over 18 years.\n* ASA score I-II-III.\n* Patients who are fully oriented and can cooperate.\n\nExclusion Criteria:\n\n* ASA score IV-V.\n* Patients who refuse to participate in the study.\n* Patients under 18 years of age.\n* Presence of active infection in the area to be operated on.\n* Chronic pain and continuous analgesic use.\n* Patients with coagulation disorders.\n* Patients who cannot cooperate with postoperative pain follow-up.\n* Patients with allergies to local anesthetic agents.\n* Presence of neuropathy or myopathy in the operated extremity.",true,"ALL","18 Years",{"count":20,"type":21},52,"ESTIMATED","INTERVENTIONAL",[24],"NA","This prospective randomized comparative study aims to compare the analgesic efficacy of pericapsular nerve group block (PENG) and lumbar erector spinae plane block (L-ESP) groups to relieve postoperative pain in participants over the age of 18 undergoing total hip arthroplasty under spinal anesthesia. The main question it aims to answer is:\n\nTo demonstrate whether PENG block or L-ESP block is more effective in postoperative analgesia in patients undergoing total hip arthroplasty surgery based on pain scores, opioid consumption, and patient satisfaction.\n\nTotal hip arthroplasties cause severe pain with movement in the postoperative period. After surgery, the movements of the participants are severely restricted, which increases the possibility of complications. In this study, the participants' pain status, VAS score, opioid consumption through patient-controlled analgesia, and patient satisfaction will be measured with a questionnaire for 24 hours at predetermined time points and then compared. Both types of blocks have pain-relieving effects. This study will only investigate which one is more effective in reducing pain, and there will be no deficiency in relieving the pain of the participants.",[27,28,29,30,31,32,33],"Opioid Consumption, Postoperative","Pain, Postoperative","Nerve Block","PENG Block","Lumbar Erector Spinae Plane Block","Hip Replacement, Total","Postoperative Analgesia",[35,31,36,37],"Pericapsular Nerve Group (PENG) Block","Total Hip Arthroplasty","Postoperative analgesia","RECRUITING","2026-05-01",{"date":41,"type":42},"2026-05-07","ACTUAL",{"date":44,"type":42},"2025-01-21",{"date":46,"type":21},"2026-06-01",{"name":48,"class":49},"Başakşehir Çam & Sakura City Hospital","OTHER_GOV",1,{"id":52,"slug":53,"hasResults":11,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":4,"eligibilityCriteria":57,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":58,"targetDuration":4,"studyType":22,"phases":60,"briefSummary":61,"conditions":62,"keywords":66,"overallStatus":72,"whyStopped":4,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":76,"completionDateStruct":77,"leadSponsor":79,"locationsCount":4},"100627511","pericapsular-nerve-group-block-versus-intrathecal-morphine-for-analgesia-after-total-hip-arthroplasty-100627511","NCT07449585","Pericapsular Nerve Group Block Versus Intrathecal Morphine for Analgesia After Total Hip Arthroplasty","Comparison of the Efficacy of the Pericapsular Nerve Group (PENG) Block Versus Intrathecal Morphine for Postoperative Analgesia Following Total Hip Arthroplasty","Inclusion Criteria:\n\n* Informed, written consent for study participation.\n* Qualification for elective primary total hip arthroplasty via a posterolateral approach.\n* Age above 18 years.\n* ASA Physical Status I-III.\n* Absence of contraindications to spinal anesthesia.\n* Absence of contraindications to performing a Pericapsular Nerve Group (PENG) block.\n* Absence of contraindications to the administration of the pharmacological agents utilized in the study.\n\nExclusion Criteria:\n\n* Absence of informed consent.\n* Age below 18 years.\n* Psychoactive substance abuse or dependence.\n* Chronic opioid therapy.\n* Contraindications to spinal anesthesia.\n* Contraindications to the Pericapsular Nerve Group (PENG) block.\n* Contraindications to the administration of study medications.\n* Body Mass Index (BMI) above 30 kg\u002Fm\\^2.\n* Pregnancy.\n* History of chronic pain management.",{"count":59,"type":21},180,[24],"The Pericapsular Nerve Group (PENG) block is an effective method for postoperative pain management in patients undergoing primary total hip arthroplasty (THA) via a posterolateral approach. The application of this technique reduces postoperative opioid requirements, thereby limiting the risk of adverse effects associated with systemic opioid administration. Effective pain control and a reduced incidence of side effects may translate into higher patient satisfaction and a decreased length of hospital stay (LOS). The PENG block serves as an effective component of multimodal analgesia and may provide an alternative to intrathecal morphine in patients undergoing primary total hip arthroplasty via a posterolateral approach, where the primary anesthetic technique is spinal anesthesia with hyperbaric bupivacaine.\n\nObjectives\n\n1. To evaluate the efficacy of the PENG block in postoperative pain control and compare its effectiveness with intrathecal morphine administration.\n2. To assess the impact of the PENG block on postoperative opioid consumption in comparison to analgesia achieved via intrathecal morphine.\n3. To analyze the incidence of selected adverse effects associated with systemic opioid administration in patients receiving a PENG block versus those in the intrathecal morphine group.\n4. To evaluate patient satisfaction levels regarding postoperative pain management across the different analgesic modalities.\n5. To analyze the correlation between the type of analgesia employed and the duration of hospitalization.",[63,32,64,65],"Perioperative Analgesia","Postoperative Pain","Hip Disease",[67,68,69,36,64,33,70,71],"Pericapsular Nerve Group Block","Intrathecal Morphine","Spinal Anesthesia","Opioid Consumption","Patient-Controlled Analgesia","NOT_YET_RECRUITING","2026-03-01",{"date":75,"type":42},"2026-03-04",{"date":73,"type":21},{"date":78,"type":21},"2028-12-31",{"name":80,"class":81},"Medical University of Gdansk","OTHER",{"id":83,"slug":84,"hasResults":11,"nctId":85,"briefTitle":86,"officialTitle":87,"acronym":4,"eligibilityCriteria":88,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":89,"enrollmentInfo":90,"targetDuration":4,"studyType":22,"phases":92,"briefSummary":93,"conditions":94,"keywords":4,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":102,"lastUpdatePostDateStruct":103,"startDateStruct":105,"completionDateStruct":107,"leadSponsor":109,"locationsCount":50},"100594265","opposed-anterior-hip-arthroplasty-regional-anesthesia-study-study-100594265","NCT07017192","OPPOSED (anteriOr hiP arthroPlasty regiOnal aneSthEsia stuDy) Study","OPPOSED (anteriOr hiP arthroPlasty regiOnal aneSthEsia stuDy) Study. Regional Anesthesia Techniques for Anterior Approach Hip Arthroplasty Analgesia: SIFI Block Versus Lumbar ESP Block","Inclusion Criteria:\n\n* Age \\>=18 years and =\\\u003C85 years\n* patients undergoing elective unilateral THA with direct anterior approach\n* patients able to understand the purposes of the study and provide signed informed consent\n\nExclusion Criteria:\n\n* pregnancy\n* Age \\\u003C18 years or \\>85 years\n* revision or bilateral surgeries\n* psychiatric pathology or cognitive deficits, mental retardation, inability to provide valid informed consent\n* History of illicit drugs and\u002For alcohol abuse\n* urgent\u002Femergent surgery with admission to Intensive Care under sedation and mechanical ventilation or complications that do not allow evaluation\n* known allergy to the drugs used in the study\n* refusal to provide informed consent","85 Years",{"count":91,"type":21},50,[24],"Main indications for total hip arthroplasty (THA) are degenerative osteoarthritis of the coxofemoral joint, osteonecrosis of the hip, congenital disorders such as dysplasia and inflammatory arthritis. More recently, surgery using the direct anterior approach is getting popularity: this method, in fact, granting a significant sparing of the hip muscles, is associated with favorable results compared to other techniques, such as a lower risk of dislocation, limitated damage to soft tissues with better recovery and early discharge.\n\nPatients undergoing this procedure may although experience moderate to severe postoperative pain in the first few hours (with peaks observed in the first 12 hours), as well as potential complications such as nausea and vomiting related to opioids use.\n\nIt has been shown that adequate pain control influences early mobilization and rehabilitation, ensuring a quicker recovery. The role of regional anesthesia techniques has been established in almost all areas of orthopedic surgery, and in particularly in the management of postoperative pain following hip replacement surgery, but definitive data are missing with regard to direct anterior approach.\n\nRegional anesthesia consists of infiltrating local anesthetics in sites (fascial planes or nerves), in order to limit or even eliminate the use of traditional painkillers, with a significant reduction in the side effects.\n\nThe aim of this study is to compare the impact of two techniques, the Suprainguinal Fascia Iliaca (SIFI) block and the lumbar Erector Spinae Plane (ESP) block, in managing postoperative pain in subjects undergoing total hip replacement surgery performed by direct anterior approach.\n\nThe primary objective of the study is the incidence of residual femoral and obturator nerves block (knee extension and hip adduction according to ASIA score) 8 hours after surgery in the two treatment groups.\n\nSecondary objectives include: • Time elapsed between the end of surgery and the recovery of lower limb motility enough to allow the patient to mobilize independently; • Total opioid consumption (calculated as morphine equivalents) at 8, 24 and 48 hours after surgery; • Pain according to NRS (numerica rating scale) at 8, 24 and 48 hours after surgery; • Extent of sensory block of the three branches of the lumbar plexus (femoral, obturator, lateral femorocutaneuous nerves) at 8, 24 and 48 hours after surgery; • Timing of hospital discharge; • Incidence of chronic or persistent postoperative pain (at 30 and 90 days after surgery); • Any postoperative complication",[95,32,96,97,98,99,100,101],"Hip Replacement Surgery","Hip Pain","Hip Arthroplasty","Hip Replacement Postoperative","Hip Surgery","Pain,Postoperative","Mobility and Independence","2025-06-27",{"date":104,"type":42},"2025-06-29",{"date":106,"type":42},"2025-06-23",{"date":108,"type":21},"2026-09-23",{"name":110,"class":81},"A.O.U. Città della Salute e della Scienza",{"id":112,"slug":113,"hasResults":11,"nctId":114,"briefTitle":115,"officialTitle":116,"acronym":117,"eligibilityCriteria":118,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":89,"enrollmentInfo":119,"targetDuration":4,"studyType":22,"phases":121,"briefSummary":122,"conditions":123,"keywords":124,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":134,"lastUpdatePostDateStruct":135,"startDateStruct":137,"completionDateStruct":139,"leadSponsor":141,"locationsCount":143},"100585914","balance-rehabilitation-based-on-serious-games-100585914","NCT06908564","Balance Rehabilitation Based on Serious Games","Efficacy of BalancE RehabiliTation Based on Serious Games in People With Hip Arthroplasty: a Pilot Non-Randomized Multicenter Study","BERTHA","Inclusion Criteria:\n\n* Age over 18 years;\n* First elective hip arthroplasty;\n* Cognitive ability to understand and perform the exercises outlined in the protocol;\n* Ability to sign the informed consent.\n\nExclusion Criteria:\n\n* Unable to adhere to the exercise program due to poor compliance;\n* Previous contralateral hip arthroplasty;\n* Surgical wound complications;\n* Severe cognitive, linguistic, or visual impairments (inability to understand and follow the study procedures);\n* Conditions that, in the investigator's judgment, may interfere with the study or contraindicate participation for safety reasons;\n* Diagnosis of epilepsy;\n* Presence of implanted cardiac pacemakers;\n* Lack of signed informed consent for the study.",{"count":120,"type":21},20,[24],"The effects of new technologies, particularly exergames, on the rehabilitation process of patients with hip arthroplasty have not yet been verified. For this reason, the aim of this study is to evaluate the effectiveness, in terms of balance recovery, of a balance rehabilitation program based on serious games in individuals with hip arthroplasty compared to conventional treatment.",[32],[125,126,127,128,129,130,131,132,133],"Hip Arthroplasty Replacement","Lower Limb","Balance","Rehabilitation","Robotic-Assisted Therapy","Range Of Motion","Pain","Activity of Daily Living","Hip Replacement Total","2025-04-07",{"date":136,"type":42},"2025-04-09",{"date":138,"type":42},"2023-06-23",{"date":140,"type":21},"2026-03-23",{"name":142,"class":81},"IRCCS San Raffaele Roma",2]