[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"hospital-acquired-condition\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:hospital-acquired-condition":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,6,0,[8,43,67,101,130,152],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":42},"100495034","assisted-ambulation-to-improve-health-outcomes-for-older-medical-inpatients-100495034",false,"NCT05725928","Assisted Ambulation to Improve Health Outcomes for Older Medical Inpatients","Randomized Trial of Assisted Ambulation to Improve Health Outcomes for Older Medical Inpatients","Inclusion Criteria:\n\nParticipants must meet all of the inclusion criteria listed below to participate in this study:\n\n1. ≥65 years of age\n2. Admitted to a medical service\n3. Complete history and physical examination on file\n4. 6-Clicks score of 16-23\n5. Insurance with Traditional Medicare or Medicare Advantage\n\nExclusion Criteria:\n\nAny patient meeting any of the exclusion criteria listed below at baseline will be excluded from study participation:\n\n1. Significant language barrier that requires a translator (other than Spanish at Baystate site only)\n2. Discharge planned for that day or the following day\n3. Observation status\n4. Surgical procedure planned\n5. Patients diagnosed with unstable angina or other medical conditions precluding participation in exercise\u002Fambulation\n6. Permanent residence in a skilled nursing facility\n7. Comfort care measures only\n8. \\>48 hours since admission\n9. Active infection with COVID-19\n10. Other active infection requiring contact or droplet precautions\n11. Order for bedrest","ALL","65 Years",{"count":19,"type":20},3000,"ESTIMATED","INTERVENTIONAL",[23],"NA","The investigator proposes to conduct a randomized trial of supervised ambulation delivered by mobility technician (MT) up to three times daily, including weekends, to hospitalized medical patients. The aims of the study are to compare the short and intermediate-term outcomes of patients randomized to the intervention versus those patients randomized to receive usual care, to identify patients who are most likely to benefit from the intervention and to assess whether the intervention increases or decreases overall costs of an episode of care, including the cost of the MTs, the index hospitalization and the first 30 days post enrollment.",[26,27,28,29],"Mobility Limitation","Frailty","Hospital Acquired Condition","Weakness, Muscle","RECRUITING","2026-06-05",{"date":33,"type":34},"2026-06-08","ACTUAL",{"date":36,"type":34},"2023-05-15",{"date":38,"type":20},"2026-12-01",{"name":40,"class":41},"The Cleveland Clinic","OTHER",5,{"id":44,"slug":45,"hasResults":11,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":49,"eligibilityCriteria":50,"healthyVolunteers":11,"sex":16,"minAge":51,"maxAge":4,"enrollmentInfo":52,"targetDuration":4,"studyType":21,"phases":54,"briefSummary":55,"conditions":56,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":57,"lastUpdatePostDateStruct":58,"startDateStruct":60,"completionDateStruct":62,"leadSponsor":64,"locationsCount":66},"100543724","re-purposing-the-ordering-of-routine-laboratory-tests-in-hospitals-in-british-columbia-100543724","NCT06359587","Re-Purposing the Ordering of Routine Laboratory Tests in Hospitals in British Columbia","Re-Purposing the Ordering of Routine Laboratory Testing in Hospitalized Medical Patients in British Columbia","RePORT-BC","Participants involved in this study include the following groups: patients and healthcare providers (including learners, physicians and allied health staff)\n\nInclusion Criteria:\n\n* Patients: The study will include all adult general medical patients that are admitted to the selected hospital during the study period under general internal medicine or family medicine (hospitalist) provider groups.\n* Attending Physicians: All physicians who provide patient care in the general internal medicine or family medicine (hospitalist) provider groups in selected hospitals\n* Learners and allied health staff (Medical Students\u002FResident physicians\u002FClinical Assistants\u002F Nurse Practitioners, etc.): All those who help take care of patients and can order labs during the study period in the under general internal medicine or family medicine (hospitalist) provider groups in selected hospitals The date range for both groups will extend from May 2024 until study completion in October 2026.\n\nExclusion Criteria:\n\n* Patients: all patients in specialized medical units (e.g., coronary care, dialysis units, bone marrow transplants units etc.), in critical care, pediatric, obstetrical, surgical, and psychiatric units.\n* Patients and Health Care Providers (HCPs) who are not in the internal medicine or family medicine groups","18 Years",{"count":53,"type":20},700000,[23],"The goal of this stepped-wedge cluster randomized trial is to assess the impact of a laboratory test overuse intervention bundle on laboratory test utilization in 6 health authorities (16 hospitals) in British Columbia. The main question it aims to answer is if the intervention bundle, inclusive of healthcare provider and patient engagement tools, can be effectively implemented for hospitalized medical inpatients in 16 hospitals across BC and reduce laboratory test over-use. Researchers will compare hospital clusters that receive the intervention at different (sequential) time points to see if there are significant changes in the measured outcomes after the intervention.",[28],"2026-04-30",{"date":59,"type":34},"2026-05-07",{"date":61,"type":34},"2024-05-06",{"date":63,"type":20},"2026-11-16",{"name":65,"class":41},"University of British Columbia",4,{"id":68,"slug":69,"hasResults":11,"nctId":70,"briefTitle":71,"officialTitle":71,"acronym":72,"eligibilityCriteria":73,"healthyVolunteers":74,"sex":16,"minAge":51,"maxAge":75,"enrollmentInfo":76,"targetDuration":4,"studyType":21,"phases":78,"briefSummary":79,"conditions":80,"keywords":85,"overallStatus":91,"whyStopped":4,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":95,"completionDateStruct":97,"leadSponsor":99,"locationsCount":4},"100614595","bedside-bike-early-mobilization-program-for-inpatients-100614595","NCT07281638","Bedside Bike Early Mobilization Program for Inpatients","BB-STEP","Inclusion Criteria:\n\n* Age 18 years or older\n* Admitted to participating hospital unit within 24 hours or less\n* Expected hospital stay of at least 3 days\n* Able to follow one-step commands\n* Anti-gravity leg strength\n* Informed consent obtained from patient or legally authorized representative\n\nExclusion Criteria:\n\n* Hemodynamic instability requiring vasopressor support with systolic blood pressure \\\u003C90 mmHg\n* Requiring fraction of inspired oxygen (FiO₂) \\>0.6 or positive end-expiratory pressure (PEEP) \\>8 cm H₂O\n* Uncontrolled cardiac arrhythmia\n* Open lower extremity wounds within the pedal arc area\n* Lower limb fracture requiring traction or immobilization\n* Active deep vein thrombosis (DVT) without therapeutic anticoagulation\n* Body mass index (BMI) \\>45 kg\u002Fm² (exceeds device reach limit)\n* Current pregnancy\n* Concurrent enrollment in another interventional clinical trial that would conflict with study procedures or outcomes",true,"110 Years",{"count":77,"type":20},80,[23],"Hospital immobility leads to serious complications including muscle loss, weakness, delirium, pressure ulcers, and blood clots. Despite being medically stable, hospitalized patients spend over 90% of their time in bed due to staffing shortages, fall risks, and limited physical therapy availability. Within one week of admission, patients can lose approximately 2% of thigh muscle mass per day, and nearly half develop clinically significant hospital-acquired weakness.The Bedside Bike is a portable, low-resistance exercise device that clamps securely to hospital beds, allowing patients to perform leg and arm cycling exercises safely without leaving their bed. This study will evaluate whether hospitalized patients at Indiana University Health facilities can feasibly and safely use the Bedside Bike to maintain mobility during their hospital stay.This quality improvement study will enroll 80 adult inpatients expected to stay at least 3 days. All participants will receive the Bedside Bike in addition to usual care (standard physical therapy and medical treatment). The study will measure how often patients use the device, whether it is safe (tracking any device-related problems), and whether it may help improve outcomes such as hospital length of stay, functional mobility scores, discharge to home, and rates of hospital-acquired weakness. Participants will have functional assessments at admission and discharge, use the Bedside Bike throughout their hospitalization (targeting at least 15 minutes daily), and be followed for 60 days after discharge to track readmissions, falls, living arrangements, and mortality.",[81,82,83,28,84,26],"Immobility Syndrome","Deep Venous Thrombosis","Delirium","Fall",[86,87,88,89,90],"Immobility Harm","Hospital-Acquired Disability","Falls","Deconditioning","In-bed exercise","NOT_YET_RECRUITING","2026-03-24",{"date":94,"type":34},"2026-03-27",{"date":96,"type":20},"2026-07-05",{"date":98,"type":20},"2026-12-31",{"name":100,"class":41},"Indiana University",{"id":102,"slug":103,"hasResults":11,"nctId":104,"briefTitle":105,"officialTitle":106,"acronym":107,"eligibilityCriteria":108,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":109,"targetDuration":4,"studyType":111,"phases":4,"briefSummary":112,"conditions":113,"keywords":115,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":120,"lastUpdatePostDateStruct":121,"startDateStruct":123,"completionDateStruct":125,"leadSponsor":127,"locationsCount":129},"100541174","delirium-identification-in-older-patients-with-alzheimers-and-other-related-dementias-in-the-emergency-department-100541174","NCT06326424","Delirium Identification in Older Patients With Alzheimer's and Other Related Dementias In the Emergency Department","Delirium Identification in Older Patients With Alzheimer's and Other Related Dementias In the Emergency Department Using Wrist Accelerometer Biosensors and Machine Learning","DELIRIUM","Inclusion Criteria:\n\n* adults patients 65+ years old with a known diagnosis of dementia or medical team highly suspects or confirms dementia this visit.\n* Emergency Department visit and\u002For hospitalization anticipated to last \\>4 more hours from the time of enrollment.\n\nExclusion Criteria:\n\n* Intubation\u002Fmechanical ventilation\n* Patients undergoing a procedure requiring sedation\n* Patients who cannot consent due to cognitive impairment and do not have a legally authorized representative or caregiver present.",{"count":110,"type":20},60,"OBSERVATIONAL","Delirium is highly prevalent and very bad for patients with dementia. Delirium is a dangerous medical condition that occurs in 6-38% of older Emergency Department patients and 70% of ICU patients. A person who develops delirium in the ED or hospital has a 12 times higher odds of being newly diagnosed with dementia in the next year compared to a similar patient who does not become delirious. Delirium is especially dangerous for persons living with Alzheimer Disease and Related Dementias (AD\u002FADRD). Persons living with ADRD have an almost 50% chance of developing delirium in the hospital.\n\nClinicians are bad at recognizing delirium. A recent systematic review led by the Geriatric Emergency Care Applied Research network (NIH funded) found that current delirium screening tools are at most 64% sensitive, meaning that physicians can identify some phenotypes of delirium well, but cannot easily rule out delirium in acutely ill older patients.\n\nThe investigators propose integrating wrist biosensors into the emergency management of older adults with dementia. The investigators will monitor heart rate variability, movement, and electrodermal activity (electrical activity of at the level of the skin) to determine if an array of biosensors more sensitive to delirium than current verbal screening tools.",[83,114,28],"Dementia",[116,117,118,119],"emergency department","delirium","older adults","dementia","2025-03-30",{"date":122,"type":34},"2025-04-03",{"date":124,"type":34},"2024-04-10",{"date":126,"type":20},"2026-03-01",{"name":128,"class":41},"Ohio State University",1,{"id":131,"slug":132,"hasResults":11,"nctId":133,"briefTitle":134,"officialTitle":135,"acronym":4,"eligibilityCriteria":136,"healthyVolunteers":11,"sex":16,"minAge":51,"maxAge":4,"enrollmentInfo":137,"targetDuration":4,"studyType":21,"phases":139,"briefSummary":140,"conditions":141,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":142,"lastUpdatePostDateStruct":143,"startDateStruct":145,"completionDateStruct":147,"leadSponsor":149,"locationsCount":129},"100514087","comprehensive-intervention-to-improve-environmental-disinfection-100514087","NCT05973916","Comprehensive Intervention to Improve Environmental Disinfection","A Comprehensive Intervention to Improve the Level of Cleaning and Disinfection of Patients' Units, in Order to Reduce New Acquisitions and Environmental Contamination by Multidrug Resistant Organisms: a Prospective Controlled Crossover Trial, Using VYV Led Lights and Continuous Air Filtering of Patients' Rooms, Coupled With Establishment of a \"Patient's Unit Commando\" Cleaning Team.","Inclusion Criteria:\n\n* Hospitalized at Medicine A or Medicine B, Shamir (Assaf Harofeh) Medical Center.\n\nExclusion Criteria:\n\n* N\u002FA",{"count":138,"type":20},1400,[23],"A comprehensive intervention to improve the level of cleaning and disinfection of patients' units, in order to reduce new acquisitions and environmental contamination by multidrug resistant organisms: a prospective controlled crossover trial, using VYV led lights and continuous air filtering of patients' rooms, coupled with establishment of a \"patient's unit commando\" cleaning team.",[28],"2024-07-30",{"date":144,"type":34},"2024-07-31",{"date":146,"type":34},"2023-08-03",{"date":148,"type":20},"2025-08-03",{"name":150,"class":151},"Assaf-Harofeh Medical Center","OTHER_GOV",{"id":153,"slug":154,"hasResults":11,"nctId":155,"briefTitle":156,"officialTitle":156,"acronym":157,"eligibilityCriteria":158,"healthyVolunteers":74,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":159,"targetDuration":4,"studyType":21,"phases":160,"briefSummary":161,"conditions":162,"keywords":168,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":175,"lastUpdatePostDateStruct":176,"startDateStruct":178,"completionDateStruct":180,"leadSponsor":182,"locationsCount":129},"100501881","yoomi-effect-of-gamified-physical-therapy-exercise-software-on-inpatient-mobility-100501881","NCT05815017","YOOMI: Effect of Gamified Physical Therapy Exercise Software on Inpatient Mobility","YOOMI","Inclusion Criteria:\n\n* \\>= 65 years of age\n* English-fluency in reading and speaking\n* Capacity to consent\n* Enrolled in HELP program\n* Attending physician confirms there are no medical contraindications to in-bed exercises\n\nExclusion Criteria:\n\n* Unstable Psychiatric Illness\n* Unstable\u002FCritically Ill Patients requiring ICU-level of care\n* Surgical tube present (e.g. JP drains)\n* Surgery during the hospitalization\n* Bed Rest Activity Order",{"count":77,"type":20},[23],"Patients admitted to the hospital often develop functional impairments due to being in bed most of the day. Each day of bedrest leads to significant muscle loss. As a result, many patients become dependent on others or require rehabilitation at a facility to improve mobility and function prior to returning home. Staff in the hospital is limited and often unable to mobilize patients every day while hospitalized. The investigators are testing a new experimental gamified physical therapy exercise software to see if it can be a fun, enjoyable way to help mobilize patients without the assistance of staff. The primary aim of this pilot\u002Fproof of concept study is to determine whether gamified physical therapy software can help inpatients exercise within the safety of their own beds and preserve pre-hospitalization function.",[29,163,164,165,28,166,167],"Delirium in Old Age","Muscle Atrophy or Weakness","Muscle Loss","Physical Disability","Physical Inactivity",[169,170,171,172,173,174],"Artificial Intelligence (AI)","Physical Therapy","Hospitalization related muscle atrophy","Hospitalization associated decline","Inpatient rehabilitation","AI driven physical therapy","2024-03-06",{"date":177,"type":34},"2024-03-08",{"date":179,"type":34},"2023-11-29",{"date":181,"type":20},"2024-12",{"name":183,"class":41},"Rutgers, The State University of New Jersey"]