[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"human-performance\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:human-performance":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,54],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":31,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":42,"lastUpdatePostDateStruct":43,"startDateStruct":46,"completionDateStruct":48,"leadSponsor":50,"locationsCount":53},"100623223","molecular-indicators-of-systematic-fitness-100623223",false,"NCT07393841","Molecular Indicators of Systematic Fitness","MISFIT","Inclusion Criteria:\n\n* Be ≥18 years old\n* Be able to understand and provide informed consent (English; additional languages may be added via amendment with translated materials)\n* Be willing to complete VO₂max testing, blood draw, and questionnaires.\n* Be able to safely perform maximal\u002Fsymptom-limited exercise testing as determined by: PAR-Q+ screening and investigator review (included as an attachment) and resting vitals screening (heart rate)\n\nExclusion Criteria:\n\n* Conditions that, in the investigator's judgment, or a medical doctor, makes maximal exercise testing unsafe (e.g., unstable cardiovascular symptoms)\n* Contraindications or unwillingness to undergo venipuncture\n* Acute illness (fever, significant respiratory illness) at the time of testing\n* Failure to comply with procedures.",true,"ALL","18 Years",{"count":20,"type":21},250,"ESTIMATED","OBSERVATIONAL","The goal of this study is to characterize associations between cardiorespiratory fitness, as measured by VO₂max\u002FVO₂peak, and blood-based molecular measurements in adults. This is an observational study where research staff measures VO₂max\u002FVO₂peak and collects fasted, resting blood samples on the same day. The main questions it aims to answer are:\n\n1. Can a multi-analyte blood panel accurately predict directly measured VO₂max\u002FVO₂peak?\n2. How do these blood-based features vary across age, sex, and self-reported or documented physical activity profiles?\n3. Are the predictor analytes able to capture changes in VO₂max\u002FVO₂peak caused by a self-directed intervention (e.g., training for a marathon)?\n4. What is the analytic reliability of the predictor biomarkers?",[25,26,27,28,29,30],"Healthy Adult","Fitness Testing","Athlete","Aging","Exercise Physiology","Human Performance",[32,33,34,35,36,37,38,39,40],"VO2peak","VO2max","cardiorespiratory fitness","proteomics","blood biomarkers","cardiovascular health","oxygen transport","exercise performance","functional capacity","RECRUITING","2026-02-02",{"date":44,"type":45},"2026-02-06","ACTUAL",{"date":47,"type":45},"2026-01-05",{"date":49,"type":21},"2028-05-10",{"name":51,"class":52},"VO Health, Inc.","INDUSTRY",1,{"id":55,"slug":56,"hasResults":11,"nctId":57,"briefTitle":58,"officialTitle":58,"acronym":4,"eligibilityCriteria":59,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":60,"enrollmentInfo":61,"targetDuration":4,"studyType":63,"phases":64,"briefSummary":66,"conditions":67,"keywords":4,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":53},"100552615","the-effects-of-l-arginine-supplementation-on-anaerobic-exercise-performance-100552615","NCT06475391","The Effects of L-arginine Supplementation on Anaerobic Exercise Performance","Inclusion Criteria:\n\n* Recreationally physically active individuals will be recruited for the study. In this context it means all participants perform 1-hour of exercise per day over 3-days per week at a minimum for 1-month. All participants will be between the ages of 18-39 years of age.\n\nExclusion Criteria:\n\n* Exclusion criteria for the study includes: 1) smokers; 2) unhealthy (have cardiovascular, metabolic, neurological, or psychological disease); 3) taking medication for any condition; 4) any known allergy to the supplements of interest (L-arginine or placebo \\[dextrose\\]).","39 Years",{"count":62,"type":21},20,"INTERVENTIONAL",[65],"NA","The purpose of this study is to evaluate if acute ingestion of L-arginine will enhance anaerobic exercise performance in young, healthy, and recreationally active adults.",[68,30],"Skeletal Muscle","2024-06-25",{"date":71,"type":45},"2024-06-26",{"date":73,"type":45},"2024-06-14",{"date":75,"type":21},"2024-12-31",{"name":77,"class":78},"University of Manitoba","OTHER"]