[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"hunger\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:hunger":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,45,75,106],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":44},"100626994","hunger-perception-and-weight-related-outcomes-following-use-of-a-leptin-supporting-dietary-supplement-100626994",false,"NCT07442864","Hunger Perception and Weight-Related Outcomes Following Use of a Leptin-Supporting Dietary Supplement","Evaluation of Hunger Perception and Weight-Related Outcomes Following Use of a Leptin-Supporting Dietary Supplement Over 12 Weeks","Inclusion Criteria:\n\n* Adults aged 18 years or older\n* Willing to pay for study supplies and able to take the dietary supplement daily for 12 weeks\n* Willing to complete electronic questionnaires and self-reported measurements\n* Able to provide informed consent\n\nExclusion Criteria:\n\n* Pregnant or breastfeeding individuals\n* Known allergy or sensitivity to any supplement ingredients\n* Use of medications or supplements that could interfere with appetite or weight without medical clearance\n* Any medical condition that would make participation unsafe, as determined by the participant",true,"ALL","18 Years",{"count":20,"type":21},100,"ESTIMATED","INTERVENTIONAL",[24],"NA","This study evaluates changes in hunger perception and body composition-related measures following daily use of a commercially available dietary supplement formulated to support leptin-related metabolic signaling. Adult participants will self-administer the supplement for 12 weeks and complete periodic self-reported assessments related to appetite, hunger, and weight-related outcomes. Participants serve as their own control, with comparisons made between baseline and follow-up measurements. The study is designed to generate preliminary, real-world evidence regarding supplement use in a general wellness context.",[27,28],"Hunger","Weight Change",[27,30,31],"Leptin","Weight Management","RECRUITING","2026-02-24",{"date":35,"type":36},"2026-03-02","ACTUAL",{"date":38,"type":36},"2025-09-10",{"date":40,"type":21},"2026-09-10",{"name":42,"class":43},"Efforia, Inc","INDUSTRY",1,{"id":46,"slug":47,"hasResults":11,"nctId":48,"briefTitle":49,"officialTitle":50,"acronym":4,"eligibilityCriteria":51,"healthyVolunteers":16,"sex":17,"minAge":52,"maxAge":53,"enrollmentInfo":54,"targetDuration":4,"studyType":22,"phases":56,"briefSummary":57,"conditions":58,"keywords":62,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":44},"100622949","a-clinical-trial-to-determine-the-safety-and-efficacy-of-an-origin-satiety-complex-on-self-reported-hunger-and-satiety-in-healthy-adults-100622949","NCT07390266","A Clinical Trial to Determine the Safety and Efficacy of an Origin Satiety Complex on Self-reported Hunger and Satiety in Healthy Adults","A Randomized, Triple-blind, Placebo-controlled, Cross-over Clinical Trial to Determine the Safety and Efficacy of an Origin Satiety Complex on Self-reported Hunger and Satiety in Healthy Adults","Inclusion Criteria:\n\n1. Males \\& females 21 - 50 years of age, inclusive\n2. BMI between 18.5 - 29.9 kg\u002Fm²\n3. Females not of child-bearing potential, defined as those who have undergone a sterilization procedure (e.g. hysterectomy, bilateral oophorectomy, bilateral tubal ligation, complete endometrial ablation) or have been post-menopausal for at least 1 year prior to screening Or,\n\n   Individuals of child-bearing potential must have a negative baseline urine pregnancy test and agree to use a medically approved method of birth control for the duration of the study. All hormonal birth control must have been in use for a minimum of three months. Acceptable methods of birth control include:\n   * Hormonal contraceptives including oral contraceptives, hormone birth control patch (Ortho Evra), vaginal contraceptive ring (NuvaRing), injectable contraceptives (Depo-Provera, Lunelle), or hormone implant (Norplant System)\n   * Double-barrier method\n   * Intrauterine devices\n   * Non-heterosexual lifestyle and agrees to use contraception if planning on changing to heterosexual partner(s)\n   * Vasectomy of partner at least 6 months prior to screening\n   * Abstinence and agrees to use contraception if planning on becoming sexually active during the study\n4. Willingness to complete questionnaires, records, and diaries associated with the study and to complete all clinic visits\n5. Agrees to maintain current lifestyle habits (diet, physical activity, medications, supplements, and sleep) as much as possible throughout the study\n6. Agrees to consume the standardized dinner the night prior to study visits and comply with fasting requirements\n7. Agrees to avoid alcohol consumption in the 24 hours prior to clinic visits and caffeine consumption and physical exercise on the morning of each study visit\n8. Provided voluntary, written, informed consent to participate in the study\n9. Healthy as determined by medical history as assessed by the Qualified Investigator (QI)\n\nExclusion Criteria:\n\n1. Individuals who are pregnant, breast feeding, or planning to become pregnant during the study\n2. Allergy, sensitivity, intolerance, or dietary restriction preventing consumption of investigational product, placebo, or standardized meal ingredients\n3. Poor venous access as assessed by the QI\n4. Following a specific diet (e.g., vegetarian, paleo, ketogenic, carnivore, etc.), as assessed by the QI\n5. Unstable metabolic disease or chronic diseases as assessed by the QI\n6. Current or history of any significant diseases of the gastrointestinal tract as assessed by the QI\n7. Current or history of eating disorders or restricted eating as assessed by the QI\n8. Unstable hypertension. Treatment on a stable dose of medication for at least 3 months will be considered by the QI (See Section 7.3)\n9. Type I or Type II diabetes\n10. Significant cardiovascular event in the past 6 months. Participants with no significant cardiovascular event on stable medication may be included after assessment by the QI on a case-by-case basis\n11. History of or current diagnosis with kidney and\u002For liver diseases as assessed by the QI on a case-by-case basis, with the exception of history of kidney stones in participants who are symptom free for 6 months\n12. Self-reported confirmation of current or pre-existing thyroid condition. Treatment on a stable dose of medication for at least 3 months will be considered by the QI\n13. Major surgery in the past 3 months or individuals who have planned surgery during the course of the study. Participants with minor surgery will be considered on a case-by-case basis by the QI\n14. Gastric bypass surgery or other surgeries to induce weight loss\n15. Cancer, except skin basal cell carcinoma completely excised with no chemotherapy or radiation with a follow up that is negative. Volunteers with cancer in full remission for more than five years after diagnosis are acceptable\n16. Individuals with an autoimmune disease or are immune compromised as assessed by the QI\n17. Self-reported confirmation of a HIV-, Hepatitis B- and\u002For C-positive diagnosis as assessed by the QI\n18. Self-reported confirmation of blood\u002Fbleeding disorders as assessed by the QI\n19. Self-reported confirmation of hypercalcemia and\u002For hypercalciuria diagnosis, as assessed by the QI\n20. Use of medical cannabinoid products\n21. Chronic use of cannabinoid products (\\>2 times\u002Fweek). Occasional users will be required to washout and abstain for the duration of the study period\n22. Regular use of tobacco or nicotine products in the past six months, as assessed by the QI. Occasional users will be required to washout and abstain for the duration of the study period\n23. Alcohol intake average of \\>2 standard drinks per day as assessed by the QI\n24. Alcohol or drug abuse within the last 12 months\n25. Current use of prescribed and\u002For over-the-counter (OTC) medications, supplements, and\u002For consumption of food\u002Fdrinks that may impact the safety and\u002For efficacy of the investigational product (Sections 7.3.1 and 7.3.2)\n26. Participation in other clinical research studies 30 days prior to baseline, as assessed by the QI\n27. Individuals who are unable to give informed consent\n28. Any other condition or lifestyle factor, that, in the opinion of the QI, may adversely affect the participant's ability to complete the study or its measures or pose significant risk to the participant","21 Years","50 Years",{"count":55,"type":21},30,[24],"The goal of this clinical trial is to the safety and efficacy of the investigational product (IP), Origin Satiety Complex, on hunger and satiety in healthy adults. The main question it aims to answer is what is the difference in the net incremental area under the curve (niAUC) for self-reported postprandial hunger and satiety (T = 0 - T = 10.5 h), as assessed by satiety and hunger items of the Eating Behavior Visual Analog Scales (VAS), between the IP and placebo.",[59,27,60,61],"High BMI","Satiety","Healthy Adults",[63,64],"Vora Life","Origin Satiety Complex","NOT_YET_RECRUITING","2026-01-28",{"date":68,"type":36},"2026-02-05",{"date":70,"type":21},"2026-03",{"date":72,"type":21},"2026-04",{"name":74,"class":43},"Vora Life LLC",{"id":76,"slug":77,"hasResults":11,"nctId":78,"briefTitle":79,"officialTitle":80,"acronym":4,"eligibilityCriteria":81,"healthyVolunteers":16,"sex":17,"minAge":82,"maxAge":4,"enrollmentInfo":83,"targetDuration":4,"studyType":22,"phases":85,"briefSummary":86,"conditions":87,"keywords":91,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":96,"lastUpdatePostDateStruct":97,"startDateStruct":99,"completionDateStruct":101,"leadSponsor":103,"locationsCount":44},"100454378","maximizing-nutrition-education-to-meet-dietary-and-food-security-of-children-and-parents-100454378","NCT05196763","Maximizing Nutrition Education to Meet Dietary and Food Security of Children and Parents","Maximizing the Impact of Nutrition Education to Meet the Dietary Quality and Food Security Needs of Children and Parents","Inclusion Criteria:\n\n* households in Indiana\n* households with children\n* English speaking\n* eligible to receive SNAP (≥18 years and household income at or below 130% of the poverty guideline)\n* willing to allow a child 5-18 years to participate\n* willing to participate in the study and wait 1 year to receive SNAP-Ed\n\nExclusion Criteria:\n\n* not have received SNAP-Ed lessons in the past year\n* not pregnant or lactating (due to inherent dietary changes)","5 Years",{"count":84,"type":21},300,[24],"Food insecurity and low diet quality are persistent problems linked with chronic disease and poor health among limited-resource children and adults using Supplemental Nutrition Assistance Program (SNAP). We have shown nutrition education via adult-focused, direct SNAP-Education (SNAP-Ed) improved household food security by 25% but not adult dietary quality among SNAP-eligible households using a randomized, controlled, longitudinal SNAP-Ed intervention in Indiana. Households experiencing food insecurity often reserve food considered \"healthful\" for children, so child dietary quality improvement may precede that observed among adults when household food security improves. This study will determine the effect of adult-focused direct SNAP-Ed on child dietary quality and household food security using a longitudinal randomized, controlled SNAP-Ed intervention. Assessment will include repeated 24-hour dietary recalls to determine usual intake, the U.S. Household Food Security Survey Module, and behavior data from before and after the 10-week \"intervention period,\" and 1 year later, after which the control group will receive the intervention. Low-income participants (n=275) from Indiana will be recruited following SNAP-Ed protocol. Results of the study will inform the creation of supplementary on-demand SNAP-Ed educational material focused on improving healthful dietary intake for children and adults in situations of food insecurity in households with children. Education on modeling healthy attitudes and behaviors, planning and preparing family meals, and dietary shortfalls as informed by the results and previous evidence will be included and evaluated. The study aligns with the goals of USDA to increase food security and this RFP to improve healthful behaviors, food quality and nutrition.",[88,27,89,90],"Nutrition, Healthy","Diet, Healthy","Food Habits",[92,93,94,95],"food security","food insecurity","dietary quality","nutrition","2025-05-27",{"date":98,"type":36},"2025-05-31",{"date":100,"type":36},"2022-11-01",{"date":102,"type":21},"2027-12",{"name":104,"class":105},"Purdue University","OTHER",{"id":107,"slug":108,"hasResults":11,"nctId":109,"briefTitle":110,"officialTitle":111,"acronym":4,"eligibilityCriteria":112,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":113,"enrollmentInfo":114,"targetDuration":4,"studyType":22,"phases":116,"briefSummary":117,"conditions":118,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":121,"lastUpdatePostDateStruct":122,"startDateStruct":124,"completionDateStruct":126,"leadSponsor":128,"locationsCount":44},"100574767","food-orders-on-blood-glucose-and-fuel-use-at-rest-100574767","NCT06763562","Food Orders on Blood Glucose and Fuel Use At Rest","The Impact of Different Food Orders on Blood Glucose and Fuel Use At Rest","Inclusion Criteria:\n\n* 18-70 years old\n* Free from any allergy or condition that precluding consumption of edamame, butter, and rice\n* Not currently pregnant\n* Free of any medical conditions requiring the use of insulin\n* Have no history of bariatric surgery\n* Have no implanted electrical devices such as a pacemaker\n\nExclusion Criteria:\n\n* Younger than 18 and older than 70 years old\n* Having an allergy or condition that precludes consumption of edamame, butter, and rice\n* Currently pregnant\n* Any medical conditions requiring the use of insulin\n* A history of bariatric surgery\n* Having an implanted electrical device such as a pacemaker","70 Years",{"count":115,"type":21},60,[24],"Consuming a carbohydrate-rich food as the final food in a meal, as compared to the first food in a meal, has been shown to reduce blood glucose levels after eating in both diabetes patients and in healthy controls. However, gaps remain in the literature in this area of research, and currently little is known about how substrate (fuel) use is impacted by altering food order. In addition, most studies to date have used a mix of meat and plant foods, while little research has focused exclusively on vegetarian foods. This randomized experiment will examine how altering the order of foods eaten in a vegetarian meal impacts blood glucose and fuel utilization at rest.",[119,27,120],"Glucose Metabolism Disorders","Fat Burn","2025-02-16",{"date":123,"type":36},"2025-02-19",{"date":125,"type":36},"2025-01-05",{"date":127,"type":21},"2026-06-30",{"name":129,"class":105},"Old Dominion University"]