[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"hyperchloremia\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:hyperchloremia":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,40],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":4},"100641179","metabolic-and-clinical-effects-of-hyperchloremia-during-holep-surgery-100641179",false,"NCT07655830","Metabolic and Clinical Effects of Hyperchloremia During HoLEP Surgery.","Evaluation of the Metabolic and Clinical Effects of Intraoperative Hyperchloremia in Holmium Laser Enucleation of Prostate (HoLEP) Surgery.","Inclusion Criteria:\n\n* Patients scheduled for elective HoLEP surgery.\n* Patients providing written informed consent\n\nExclusion Criteria:\n\n* Preoperative metabolic acidosis.\n* Advanced renal failure.\n* Emergency surgery.\n* Missing data.",true,"MALE","18 Years",{"count":20,"type":21},45,"ESTIMATED","OBSERVATIONAL","This study aims to evaluate the changes between preoperative and postoperative serum chloride levels in patients undergoing HoLEP surgery and to investigate the metabolic and clinical effects of this change. The study is observational, and no additional interventions will be performed.",[25,26,27],"HoLEP (Holmium Laser Enucleation of Prostate)","Hyperchloremia","Perioperative Management","NOT_YET_RECRUITING","2026-06-13",{"date":31,"type":32},"2026-06-18","ACTUAL",{"date":34,"type":21},"2026-07-04",{"date":36,"type":21},"2026-09-30",{"name":38,"class":39},"Ankara City Hospital Bilkent","OTHER",{"id":41,"slug":42,"hasResults":11,"nctId":43,"briefTitle":44,"officialTitle":45,"acronym":46,"eligibilityCriteria":47,"healthyVolunteers":11,"sex":48,"minAge":18,"maxAge":4,"enrollmentInfo":49,"targetDuration":4,"studyType":51,"phases":52,"briefSummary":54,"conditions":55,"keywords":58,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":61,"lastUpdatePostDateStruct":62,"startDateStruct":64,"completionDateStruct":66,"leadSponsor":68,"locationsCount":70},"100544894","phase-4-multiple-electrolytes-injection-ii-and-normal-saline-on-hyperchloremia-in-severe-hemorrhagic-stroke-100544894","NCT06374823","Multiple Electrolytes Injection (II) and Normal Saline on Hyperchloremia in Severe Hemorrhagic Stroke","The Impact of Multiple Electrolytes Injection (II) and Normal Saline on Hyperchloremia in Severe Hemorrhagic Stroke Patients: A Prospective, Multicenter, Open-label, Randomized Controlled Study","MERIT","Inclusion Criteria:\n\n* Patients with a diagnosis of hemorrhagic stroke (cerebral hemorrhage, intraventricular hemorrhage, or subarachnoid hemorrhage confirmed by CT or MRI, except for subdural or extradural hemorrhage caused by tramma)\n* Patients requiring fluid therapy\n* Patients over 18 years old\n\nExclusion Criteria:\n\n* Hemorrhage onset more than 72hours\n* Preexisting hyperchloremia(blood chloride \\> 110mmol\u002FL)\n* Presence of hypothalamic disease or cerebral salt wasting syndrome\n* Patients who can eat by themselves\n* Patients receiving routine RRT\n* Patients with known allergic or adverse reactions to the liquid used\n* Patients with organ failure (such as heart failure, renal failure, liver failure) or end-stage disease\n* Patients with autoimmune diseases, inflammatory diseases, metabolic diseases and blood diseases\n* Patients with serious heart disease or arrhythmia\n* Patients who are expected to have difficulty complying with the study plan or collecting data completely\n* Pregnant or lactating women\n* No informed consent was signed\n* Patients participating in other clinical trials\n* Other conditions deemed by the investigator to be ineligible for participation in the study","ALL",{"count":50,"type":21},342,"INTERVENTIONAL",[53],"PHASE4","Normal saline (0.9% sodium chloride), a classical crystalloid solution, is widely used to maintain fluid balance, volume resuscitation and dilute drugs during clinical practice. However, the chloride concentration of normal saline (154mmol\u002FL) is much higher than human plasma, and a large amount of infusion may lead to iatrogenic hyperchloremia in ICU patients. In contrast, the concentrations of Multiple electrolytes II is more similar to those of plasma and is considered to be a better fluid choice than normal saline.",[56,26,57],"Critical Care","Hemorrhagic Stroke",[59,60],"Saline","Crystalloid Solution","2024-04-16",{"date":63,"type":32},"2024-04-19",{"date":65,"type":21},"2024-05",{"date":67,"type":21},"2026-12",{"name":69,"class":39},"Capital Medical University",1]