[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"hypermobile-eds-heds\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:hypermobile-eds-heds":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,47],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100628626","stable-pilates-for-hypermobility-100628626",false,"NCT07464093","STABLE Pilates for Hypermobility","Pilates for Hypermobility: A Pilot Feasibility Study","STABLE","Inclusion Criteria:\n\n* ≥ 18 years old;\n* Self-reported hypermobility with confirmed or suspected diagnosis of hEDS\u002FHSD;\n* Self-reported persistent pain ≥ 3 months;\n* A minimum of 3\u002F10 self-reported pain intensity in the past week\n* Able to get on and off the floor without assistance;\n* Able to communicate fluently in English; and\n* Able to provide written, informed consent\n\nExclusion Criteria:\n\n* Regular ongoing mind-body practice (e.g. Tai chi, yoga, pilates) defined as a regular weekly practice of at least 20min\u002Fweek over the past 6 months;\n* Recent surgery or acute bone, joint or nerve injury (\\\u003C6 months);\n* Have a history of a severe or progressive neurological or movement disorder;\n* Pregnant, planning to become pregnant during the study, or currently breast feeding;\n* Unable to get on and off the floor without assistance;\n* Unable to complete study procedures due to cognitive impairment;\n* Unable to provide written, informed consent; or\n* Currently participating in or planning to participate in another physical activity, mind-body or pain-related intervention research study in the next 4 months.","ALL","18 Years",{"count":20,"type":21},100,"ESTIMATED","INTERVENTIONAL",[24],"NA","This study is looking at whether Pilates-based exercise can help with hypermobility-related symptoms, like pain.",[27,28,29],"Ehlers-Danlos Syndrome (EDS)","Hypermobile EDS (hEDS)","Hypermobile Spectrum Disorder",[31,32,33],"hypermobility","pilates","pain","RECRUITING","2026-06-09",{"date":37,"type":38},"2026-06-11","ACTUAL",{"date":40,"type":21},"2026-07",{"date":42,"type":21},"2027-12",{"name":44,"class":45},"Brigham and Women's Hospital","OTHER",1,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":4,"eligibilityCriteria":53,"healthyVolunteers":11,"sex":54,"minAge":18,"maxAge":55,"enrollmentInfo":56,"targetDuration":4,"studyType":22,"phases":58,"briefSummary":59,"conditions":60,"keywords":63,"overallStatus":74,"whyStopped":4,"lastUpdateSubmitDate":75,"lastUpdatePostDateStruct":76,"startDateStruct":78,"completionDateStruct":80,"leadSponsor":82,"locationsCount":46},"100639329","hamstring-strengthening-in-hypermobile-conditions-100639329","NCT07626957","Hamstring Strengthening in Hypermobile Conditions","Effects and Feasibility of Eccentric Hamstring Strengthening in Hypermobility Spectrum Disorders and Hypermobile Ehlers-Danlos Syndrome","Inclusion Criteria:\n\n* Reported diagnosis of HSD or hEDS by a physician\n* Meet the 2017 International Diagnostic Criteria for HSD and hEDS\n* Clearance to participant in exercise participation, determined using the Get Active Questionnaire\n\nExclusion Criteria:\n\n* Other acquired or hereditary connective tissue disorder (i.e., rheumatoid arthritis, Marfan syndrome, etc.)\n* Currently experiencing daily knee pain\n* Prior knee injury or surgery\n* Intra-articular knee injection in the last 12 months\n* Currently pregnant","FEMALE","55 Years",{"count":57,"type":21},20,[24],"The goal of this clinical trial is to determine how strengthening the hamstring muscles affects the knee joint in people living with hypermobility spectrum disorders (HSD) and hypermobile Ehlers-Danlos syndrome (hEDS). The main questions it aims to answer are:\n\n* Does hamstring strengthening reduce the looseness of the knee joint in HSD\u002FhEDS?\n* Does hamstring strengthening improve clinical outcomes like pain in people living with HSD\u002FhEDS?\n\nParticipants will:\n\n* Attend two exercise classes per week for 12 weeks.\n* Visit the laboratory every 4-6 weeks for testing.",[28,61,29,62],"Hypermobile Ehlers-Danlos Syndrome","Hypermobility Type Ehlers-Danlos Syndrome",[64,65,66,67,68,69,70,61,71,72,73],"Exercise","Female","Knee","Joint Laxity","Hypermobility","Joint Stiffness","Ehlers-Danlos Syndrome","Hypermobility Spectrum Disorders","strengthening","eccentric","NOT_YET_RECRUITING","2026-05-29",{"date":77,"type":38},"2026-06-04",{"date":79,"type":21},"2026-06-01",{"date":81,"type":21},"2027-08-01",{"name":83,"class":45},"University of Calgary"]