[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"hypermobility-joint\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:hypermobility-joint":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,40,74],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":28,"lastUpdatePostDateStruct":29,"startDateStruct":32,"completionDateStruct":34,"leadSponsor":36,"locationsCount":39},"100585048","comparison-of-mbr--suture-tape-and-mbr-for-clai--a-prospective-cohort-study-100585048",false,"NCT06897293","Comparison of MBR + Suture Tape and MBR for CLAI : A Prospective Cohort Study","Comparison of Modified Broström Repair + Suture Tape and Modified Broström Repair for Chronic Lateral Ankle Instability : A Prospective Cohort Study","Inclusion Criteria:\n\n* Clinical diagnosis of lateral ankle instability\n* Beighton score ≥4\n* Age with 18 to 60 years\n\nExclusion Criteria:\n\n* Patients with an acute or subacute ankle injury\n* Injury of the deltoid ligament\n* Alignment of lower extremity greater than 5 degrees\n* Fractures of the lower extremity\n* Stage III or IV osteoarthritis\n* Patients who refused to participate in the study","ALL","15 Years","55 Years",{"count":20,"type":21},86,"ESTIMATED","OBSERVATIONAL","GJL is a risk factor for postoperative recurrent instability following an MBR for CLAI. Additional suture tape augmentation has been suggested to provide more strength and stability. However, the outcomes of the MBP with suture tape augmentation were unknown, which requires further exploration.",[25,26],"Ankle Sprain","Hypermobility, Joint","RECRUITING","2026-05-18",{"date":30,"type":31},"2026-05-20","ACTUAL",{"date":33,"type":31},"2021-06-01",{"date":35,"type":21},"2026-06-01",{"name":37,"class":38},"Peking University Third Hospital","OTHER",1,{"id":41,"slug":42,"hasResults":11,"nctId":43,"briefTitle":44,"officialTitle":45,"acronym":46,"eligibilityCriteria":47,"healthyVolunteers":11,"sex":16,"minAge":48,"maxAge":49,"enrollmentInfo":50,"targetDuration":4,"studyType":52,"phases":53,"briefSummary":55,"conditions":56,"keywords":59,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":73},"100537405","exercise-in-patients-with-hypermobile-joints-and-knee-pain-100537405","NCT06277401","Exercise in Patients With Hypermobile Joints and Knee Pain","High-load Resistance Training Compared With Usual Care for Treatment of Painful Knee Joint Hypermobility in Young Adults: A Randomised Controlled Trial (the HIPEr-Knee Study)","HIPEr-Knee","Inclusion criteria\n\n* Persistent knee pain for ≥ 3 months (self-reported)\n* Knee pain ≥ 30mm during the last week using a 0-100 mm visual analogue scale (VAS; 0=no pain and 100=worst imaginable pain) (self-reported)\n* Generalised joint hypermobility assessed with the Five-Part Hypermobility Questionnaire (positive ≥ 2\u002F5) (self-reported)\n* Local knee joint hypermobility using the passive hyperextension of the knee in standing (positive \\> 10 degrees of hyperextension) and confirmed in supine lying (heel resting on 20 cm high block on the bench surface), with passive knee hyperextension (positive \\> 10 degrees) (objectively measured)\n\nExclusion criteria\n\n* Diagnosed with patellar tendinopathy\n* Pregnancy or childbirth within the past year (due to increased levels of relaxin that could affect joint stability)\n* Knee surgery within the past year\n* Participation in regular structured resistance training within the past six months\n* Inability to speak and understand Danish.\n* All types of Ehlers-Danlos syndrome\n* Other heritable connective tissue disorders such as Marfan syndrome, osteogenesis imperfecta, Loeys-Dietz syndrome, Stickler syndrome, skeletal dysplasias\n* Autoimmune rheumatic connective tissue disorders such as lupus, rheumatoid arthritis; Chromosomal conditions such as Fragile X syndrome, Kabuki syndrome, Down syndrome\n* Neuromuscular disorders that can cause joints to become unstable, such as multiple sclerosis","18 Years","45 Years",{"count":51,"type":21},90,"INTERVENTIONAL",[54],"NA","Pain associated with knee joint hypermobility is common in the adult population, but evidence on treatment is sparse. This study investigates if high-load resistance training is superior to usual care in improving activity-related pain in young patients (18-45 years) with hypermobile joints and knee pain.",[26,57,58],"Hypermobility Syndrome","Knee Discomfort",[60,61,62,63],"Hypermobility","Knee pain","Treatment","Randomised controlled trial","2026-04-28",{"date":66,"type":31},"2026-04-29",{"date":68,"type":31},"2024-02-21",{"date":70,"type":21},"2027-12",{"name":72,"class":38},"University of Southern Denmark",2,{"id":75,"slug":76,"hasResults":11,"nctId":77,"briefTitle":78,"officialTitle":78,"acronym":4,"eligibilityCriteria":79,"healthyVolunteers":80,"sex":16,"minAge":48,"maxAge":81,"enrollmentInfo":82,"targetDuration":84,"studyType":22,"phases":4,"briefSummary":85,"conditions":86,"keywords":4,"overallStatus":87,"whyStopped":4,"lastUpdateSubmitDate":88,"lastUpdatePostDateStruct":89,"startDateStruct":91,"completionDateStruct":92,"leadSponsor":94,"locationsCount":39},"100596402","ultrasonographic-evaluation-of-the-ulnar-nerve-in-individuals-with-and-without-generalized-joint-hypermobility-100596402","NCT07044986","Ultrasonographic Evaluation of the Ulnar Nerve in Individuals With and Without Generalized Joint Hypermobility","Inclusion Criteria:\n\n* Aged between 18 and 40 years\n* A Beighton score of 4 or higher (indicative of Generalized Joint Hypermobility)\n* Willingness to participate in the study\n\nExclusion Criteria:\n\n* Being under 18 or over 40 years of age\n* History of surgery or fracture in the elbow region\n* Presence of active infection at the measurement site\n* Presence of congenital anomaly in the upper extremity\n* History of surgery involving neural structures in the upper extremity\n* Presence of malignancy\n* Pregnancy\n* Presence of cognitive or psychiatric disorders",true,"40 Years",{"count":83,"type":21},60,"1 Day","This study will include 30 individuals diagnosed with Generalized Joint Hypermobility (GJH) based on the Beighton score and 30 healthy controls without GJH. Participants will undergo Tinel's test and the flexion-compression test. The presence of ulnar nerve-related symptoms such as pain and numbness will be recorded. Ultrasonographic evaluation of the ulnar nerve will be performed at the level of the medial epicondyle, as well as 2 cm proximal and distal to it. Cross-sectional area and diameter of the ulnar nerve will be measured at each site, repeated three times, and the average will be used. Additionally, ulnar nerve mobility during elbow flexion and extension will be assessed. The nerve will be classified as stable if it remains within the cubital tunnel, subluxated if it moves to the level of the epicondyle, and dislocated if it shifts anterior to the medial epicondyle.",[26],"NOT_YET_RECRUITING","2025-06-22",{"date":90,"type":31},"2025-07-01",{"date":90,"type":21},{"date":93,"type":21},"2025-08-01",{"name":95,"class":38},"Beylikduzu State Hospital"]