[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"hyperreactive-airway-disease\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:hyperreactive-airway-disease":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":27,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":5},"100555251","methacholine-challenge-test-mct-in-healthy-adults-100555251",false,"NCT06509659","Methacholine Challenge Test (MCT) in Healthy Adults","Methacholine Challenge Test (MCT) in Healthy Adults: Oscillometry Measured Alone Compared to Oscillometry and FEV1 During the Same Test","Inclusion Criteria:\n\n* Forced expiratory volume in the 1. second (FEV1) \\>80%\n* FEV1\u002FFVC-ratio \\>0,7\n* FeNO \\\u003C25 pbb\n* Oxygen saturation (SatO2) \\>95%\n* Negative methacholine Challenge Test = drop in FEV1 less than 20%\n\nExclusion Criteria:\n\n* Any lung disease\n* Lung symptoms\n* Medicine for lung disease\n* Tobacco smoking\n* Ex-smokers with more than 5 package years\n* BMI (body mass index) \\>40 kg\u002Fm2",true,"ALL","18 Years","65 Years",{"count":21,"type":22},25,"ESTIMATED","OBSERVATIONAL","Knowledge of Methacholine Challenge Test (MCT) and impedance Oscillometry (IOS) is limited. Only three studies have included adult patients, and none of these with healthy controls. The three studies have combined IOS and spirometry in the same test, although it is not recommended to perform IOS after a test that requires deep breathing, e.g. FEV1 measurement. Deep breathing is considered to affect the impedance via reduced tone in the smooth muscle.",[26],"Hyperreactive Airway Disease",[28,29,30,31],"IOS","oscillometry","spirometry","bronchial hyperreactivity","RECRUITING","2024-09-17",{"date":35,"type":36},"2024-09-19","ACTUAL",{"date":38,"type":36},"2024-08-10",{"date":40,"type":22},"2024-12-23",{"name":42,"class":43},"Allergi- og Lungeklinikken, Elsinore","NETWORK"]