[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"hypertension-arterial\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:hypertension-arterial":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,49,82,105],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":48},"100639405","mitigation-of-health-effects-in-older-adults-with-hypertension-by-reducing-exposure-to-heat-and-air-pollution-100639405",false,"NCT07606859","Mitigation of Health Effects in Older Adults With Hypertension by Reducing Exposure to Heat and Air Pollution","Innovative Solutions Across the MEDiterranean for Mitigation of Climate Change-related heaLth rIsks and Enhancing Health systeM Resilience","ISMED CLIM OH","Inclusion Criteria:\n\n* Aged ≥65 years\n* Living in Barcelona (Spain) or Nicosia (Cyprus) metropolitan areas\n* Have a physician's diagnosis of arterial hypertension\n* Receive daily anti-hypertensive medication\n* Clinically stable\n\nExclusion Criteria:\n\n* Currently smoking\n* Presence of any smoking residents in the household\n* Not residing at the household for at least 5 days a week\n* Planning to move from the current home within the next two months\n* No access to Wi-Fi or 4G\u002F5G mobile phone\n* Severe chronic conditions (congestive heart failure, ischemic heart disease, significant valvular heart disease, diabetes mellitus type 2 (DM2), inflammatory diseases, renal failure, or active cancer)\n* Illicit drugs abuse\n* Alcohol abuse\n* Psychiatric disorders\n* Severe mental disability that interferes with answering questions or following instructions","ALL","65 Years",{"count":20,"type":21},102,"ESTIMATED","INTERVENTIONAL",[24],"NA","The goal of this clinical trial is to assess the effectiveness of an intervention (combination of behavioural recommendations and technical measures) in reducing personal exposure to heat and air pollution and related health effects in older adults with hypertension.\n\nThe main questions it aims to answer are:\n\n* Does the intervention (combination of behavioral recommendations for heat mitigation) reduce personal ambient temperature exposure, measured using a wearable device (iButton)?\n* Does the intervention (combination of behavioral recommendations for air pollution mitigation and use of indoor air cleaners) reduce indoor exposure to air pollution, measured using indoor air quality sensors (Purple Air)?\n* Does the intervention (combination of behavioral recommendations for heat mitigation) improve the abnormalities in circadian blood pressure variation experienced by older adults with hypertension, assessed using advanced actigraphy? Researchers will compare measurements between older adults with hypertension carrying out their daily activities in the absence of intervention (control group), those carrying out their daily activities with behavioural recommendations (recommendation intervention group) and those carrying out their daily activities with both behavioural recommendations for heat mitigation and continuous use of indoor air cleaners in their house (heat and air pollution mitigation intervention group) to see if changes in temperature exposure and sleep are different between intervention groups.\n\nParticipants will:\n\n* Wear the wearable devise for continuous personal ambient temperature monitoring (ibutton) daily for a period of three months\n* Have their core temperature measured using an eCelsius medical capsule in three repeated assessments\n* Have their blood pressure, oxygen saturation, ECG and heart rate variability measured using 24-hour advanced actigraphy in three repeated assessments\n* Provide samples of urine and blood biomarkers in three repeated assessments.",[27,28],"Hypertension Arterial","65 Years Older",[30,31,32,33,34,35],"Hypertension","Adults 65 years and older","Intervention","Personal Ambient Temperature Exposure","Indoor air quality","Indoor air purification","RECRUITING","2026-06-03",{"date":39,"type":40},"2026-06-05","ACTUAL",{"date":42,"type":40},"2026-05-01",{"date":44,"type":21},"2027-07-31",{"name":46,"class":47},"University of Cyprus","OTHER",2,{"id":50,"slug":51,"hasResults":11,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":55,"eligibilityCriteria":56,"healthyVolunteers":11,"sex":17,"minAge":57,"maxAge":4,"enrollmentInfo":58,"targetDuration":4,"studyType":22,"phases":60,"briefSummary":61,"conditions":62,"keywords":65,"overallStatus":72,"whyStopped":4,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":4},"100640071","feasibility-of-a-person-centered-nursing-intervention-on-adherence-and-control-in-patients-with-arterial-hypertension-and-diabetes-mellitus-100640071","NCT07619677","Feasibility of a Person-centered Nursing Intervention on Adherence and Control in Patients With Arterial Hypertension and Diabetes Mellitus.","Feasibility of a Person-centered Nursing Intervention on Adherence and Control in Patients With Arterial Hypertension and Diabetes Mellitus. CERCANO Pilot Trial.","CERCANO pilot","Inclusion Criteria:\n\n1. Adults (18 years or older).\n2. Diagnosis of type 2 diabetes mellitus (DM) or arterial hypertension (HTN) (or both), documented in the medical record.\n3. Prescription of pharmacological treatment for the condition.\n4. Enrollment in a cardiovascular or metabolic risk program and scheduled for a medical follow-up visit within the next 3 to 6 months.\n\nExclusion Criteria:\n\n* Mental disorders that impair autonomy or understanding of the interventions.\n* Congestive heart failure, ischemic or valvular heart disease, end-stage renal disease requiring dialysis, chemotherapy treatment, autoimmune diseases, recent hospitalization due to disease decompensation (within the last month), or any other condition preventing the patient from receiving general health recommendations according to their primary diagnosis.\n* Physical limitations such as quadriplegia, total loss of motor function, or contraindications to physical activity as indicated by medical prescription.","18 Years",{"count":59,"type":21},100,[24],"Background. Approximately 80% of people with type 2 diabetes mellitus (DM) or arterial hypertension (HTN) do not achieve adequate disease control.\n\nObjective. To evaluate the feasibility of a research study assessing the impact of an educational and nursing counseling intervention with a person-centered care (PCC) approach to improve adherence and control in patients with arterial hypertension and diabetes mellitus in Colombia.\n\nMethods. A pilot randomized controlled clinical trial will be conducted. Adults with DM or HTN enrolled in cardiovascular or metabolic risk programs will be included. A total of 100-200 patients is expected to be recruited. The intervention group will receive counseling and education tailored to their preferences following the PCC approach, while the control group will receive standard care according to the program they belong to. Follow-up will last 6 months, and the primary outcomes to be measured in both groups are: medication adherence, DM control (HbA1c at target levels, change in HbA1c), and HTN control (SBP and DBP at target levels, changes in SBP and DBP).\n\nResults. The findings of this study will provide insight into the feasibility of conducting larger-scale studies to evaluate the effectiveness of PCC-based interventions in Colombia.",[63,64,27],"Diabete Type 2","Diabetes Education",[66,30,67,68,69,70,71],"Person-centered care","Diabetes type 2","Control","Adherence","Nursing interventions","Education","NOT_YET_RECRUITING","2026-06-01",{"date":75,"type":40},"2026-06-04",{"date":77,"type":21},"2026-06",{"date":79,"type":21},"2027-03",{"name":81,"class":47},"Universidad Autónoma de Bucaramanga",{"id":83,"slug":84,"hasResults":11,"nctId":85,"briefTitle":86,"officialTitle":87,"acronym":4,"eligibilityCriteria":88,"healthyVolunteers":11,"sex":17,"minAge":57,"maxAge":4,"enrollmentInfo":89,"targetDuration":4,"studyType":22,"phases":91,"briefSummary":92,"conditions":93,"keywords":4,"overallStatus":72,"whyStopped":4,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":98,"completionDateStruct":100,"leadSponsor":102,"locationsCount":104},"100606700","potassium-rich-salt-substitutes-in-kidney-transplant-recipients-100606700","NCT07178964","POTASSIUM-RICH SALT SUBSTITUTES IN KIDNEY TRANSPLANT RECIPIENTS","THE USE OF POTASSIUM-RICH SALT SUBSTITUTES IN BLOOD PRESSURE CONTROL OF KIDNEY TRANSPLANT RECIPIENTS","Inclusion Criteria:\n\n* patients with a transplanted kidney ≥ 3 months post kidney-transplant\n* a functioning transplanted kidney with estimated glomerular filtration rate (eGFR) according to CKD\u002FEPI equation of at least 25 ml\u002Fmin\n* Elevated blood pressure\u002Fhypertension at the time of examination at the Kidney Transplantation Center outpatient clinic, determined by standardized blood pressure measurement (RR ≥ 130\u002F80 mmHg)\n* Age ≥ 18 years\n\nExclusion Criteria:\n\n* eGFR according to CKD\u002FEPI equation below 25 ml\u002Fmin\n* serum potassium \\> 5 mmol\u002Fl\n* history of unexplained hyperkalemia\n* pregnancy or planning of pregnancy\n* inability to provide informed consent or to participate in the study (mental retardation, psychiatric illness in an uncontrolled phase)\n* multiple organ transplantation\n* Consuming most of daily meals outside the home environment",{"count":90,"type":21},80,[24],"Excessive sodium intake and inadequate potassium intake in the diet are known risk factors for the development of arterial hypertension and an increased risk of cardiovascular events. Data from randomized controlled trials show that the use of salt substitutes with reduced sodium and increased potassium content represent an effective way to reduce dietary sodium intake, blood pressure and the occurrence of cardiovascular events. Patients adhere well to the use of salt substitutes as they do not have to change their daily cooking and seasoning habits and the taste is comparable to that of regular salt. The World Health Organization (WHO) also suggests the use of salt substitutes as an acceptable strategy for reducing dietary salt intake and thus lowering blood pressure and the burden of cardiovascular disease. Recommendations for the use of salt substitutes are not uniform, primarily because of the potential risk of adverse events with increased potassium intake in some individuals, such as patients with advanced chronic kidney disease (CKD), patients receiving potassium-sparing diuretics, and patients receiving potassium supplements.\n\nNephrology guidelines rarely comment on the use of potassium-rich salt substitutes or discourage their use in patients with advanced stage 4 and 5 CKD, with the exception of Chinese guidelines, which mention the use of potassium-rich salt substitutes in CKD patients not on dialysis depending on serum potassium levels. CKD patients have largely been excluded from clinical trials of potassium-rich salt substitutes, so there is insufficient data on their safety and efficacy in CKD patients.\n\nIn this randomized controlled trial, we will investigate the effects of using potassium-enriched salt substitutes on blood pressure control and serum potassium levels in kidney transplant recipients. In the intervention group, patients will use potassium-enriched salt substitutes at home in a ratio of 75% sodium chloride and 25% potassium chloride instead of regular table salt (100% sodium chloride) for cooking and seasoning food. In the control group, patients will use regular salt at home for cooking and seasoning food. The intervention and control groups will each include 40 to 50 patients who will be monitored for 12 weeks. The study's main focus will be the change in serum potassium and blood pressure before and after the intervention.\n\nWe expect to confirm the positive effects of potassium-enriched salt substitutes on blood pressure in kidney transplant recipients without causing undesirable hyperkalemia.",[27,94],"Kidney Transplant","2025-09-10",{"date":97,"type":40},"2025-09-17",{"date":99,"type":21},"2025-10-01",{"date":101,"type":21},"2026-09-30",{"name":103,"class":47},"University Medical Centre Ljubljana",1,{"id":106,"slug":107,"hasResults":11,"nctId":108,"briefTitle":109,"officialTitle":109,"acronym":110,"eligibilityCriteria":111,"healthyVolunteers":11,"sex":17,"minAge":57,"maxAge":4,"enrollmentInfo":112,"targetDuration":4,"studyType":114,"phases":4,"briefSummary":115,"conditions":116,"keywords":120,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":127,"lastUpdatePostDateStruct":128,"startDateStruct":130,"completionDateStruct":132,"leadSponsor":134,"locationsCount":104},"100511691","etiological-diagnosis-of-cardiac-diseases-based-on-echocardiographic-images-and-clinical-data-100511691","NCT05942729","Etiological DiagnOsis of caRdiac Diseases Based on echoCardiograpHIc Images and Clinical Data.","ORCHID","Inclusion Criteria:\n\n* Patients with transthoracic echocardiography with satisfactory image quality (sufficient echogenicity)\n\nExclusion Criteria:\n\n* Minor patients\n* Patients under curatorship or guardianship",{"count":113,"type":21},1000,"OBSERVATIONAL","Research hypothesis - Recent studies have shown that high-dimensional descriptors of the cardiac function can be efficiently exploited to characterize targeted pathologies. In this project, the investigators hypothesize that echocardiograms possess a wealth of information that is currently under-exploited and that, combined with relevant patient data, will allow the development of robust and accurate digital tools for etiological diagnosis.\n\nObjectives - Based on key advances recently obtained in image analysis, notably by members of the consortium, the objective of this project is to develop rigorous and explainable cardiac disease prediction models from echocardiography based on the transformer paradigm (AI). The strength of this study lies in the development of a strong AI framework to model the complex interactions between high-quality image-based measurements extracted from echocardiograms and relevant patient data to automatically predict etiological diagnosis of cardiac diseases",[27,117,118,119],"Hypokinetic","Cardiomyopathies","Left Ventricular Hypertrophy",[30,121,122,123,124,125,126],"HTN","Arterial Hypertension","Artificial Intelligence","AI","Cardiac remodelling","Left ventricular hypertrophy","2023-07-12",{"date":129,"type":40},"2023-07-13",{"date":131,"type":40},"2023-01-01",{"date":133,"type":21},"2027-01-01",{"name":135,"class":47},"Hospices Civils de Lyon"]