[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"hypertensive-disorders-of-pregnancy-hdp\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:hypertensive-disorders-of-pregnancy-hdp":28},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,47,72],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":29,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100643173","mobile-health-program-for-post-preeclampsia-hypertension-100643173",false,"NCT07599579","Mobile Health Program for Post-Preeclampsia Hypertension","Multilevel Mobile Health Program to Improve Hypertension Among Midlife Women After Hypertensive Disorder of Pregnancy","Inclusion Criteria:\n\n* Women who had a history of HDP (either gestational HTN or preeclampsia) diagnosed by ACOG guidelines at the time of delivery at Magee-Womens Hospital between 2008 and 2015, thus 10 to 20 years from their index pregnancy complicated by HDP.\n* Evidence of current stage 2 HTN (BP ≥ 140\u002F90 mmHg with or without treatment with antihypertensive medication).\n\nExclusion Criteria:\n\n* Known clinical CVD (prior myocardial infarction, stroke, heart failure, or peripheral arterial disease).\n* Males will also be excluded from this study as it focuses on pregnancy related conditions.\n* Children will be excluded as the study is only recruiting people who are 10-20 years postpartum.","FEMALE","18 Years",{"count":19,"type":20},50,"ESTIMATED","INTERVENTIONAL",[23],"NA","Strategies targeted to optimize hypertension (HTN) control for midlife women after hypertensive disorders of pregnancy (HDP) have not been studied, despite evidence of a critical need. This proposal targets the 10-20 years postpartum as a key time when women have subclinical cardiovascular (CV) sequelae of uncontrolled HTN and are primed for CV prevention interventions. Before proceeding with large-scale intervention trials of a home blood pressure monitoring (HBPM) and coaching intervention following HDP, further pilot testing is necessary. The overarching hypothesis of this proposal is that a new monitoring and treatment paradigm utilizing HBPM combined with a virtual coaching intervention would be better than standard of care for mid-life women with prior HDP who develop HTN. Women will be assigned in an unblinded manner to the intervention or standard of care control group.",[26,27,28],"Hypertension (HTN)","Preeclampsia","Hypertensive Disorders of Pregnancy (HDP)",[30,31,32,33],"hypertension","preeclampsia","coaching","home blood pressure monitoring","NOT_YET_RECRUITING","2026-06-04",{"date":37,"type":38},"2026-06-08","ACTUAL",{"date":40,"type":20},"2026-06",{"date":42,"type":20},"2027-10",{"name":44,"class":45},"University of Pittsburgh","OTHER",1,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":4,"eligibilityCriteria":53,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":54,"targetDuration":4,"studyType":21,"phases":56,"briefSummary":57,"conditions":58,"keywords":61,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":46},"100640668","clinician-notification-to-increase-aspirin-prophylaxis-for-preeclampsia-prevention-100640668","NCT07614893","Clinician Notification to Increase Aspirin Prophylaxis for Preeclampsia Prevention","A Pragmatic Cluster-Randomized Trial of Clinician Notification to Increase Aspirin Prophylaxis Utilization Among Pregnant Individuals at Elevated Risk for Preeclampsia","Inclusion Criteria:\n\n* Pregnant individuals receiving outpatient obstetric care at participating medical centers.\n* Age 18 years or older.\n* Currently pregnant and within 12 to 28 weeks' gestation\n* Identified as having elevated predicted risk for preeclampsia as defined by USPSTSF and ACOG criteria\n* Receiving care from a clinician, care team, or clinic participating in the randomized implementation trial.\n\nExclusion Criteria:\n\n* Known contraindication to aspirin prophylaxis documented in the electronic health record.\n* Pregnancy beyond the prespecified gestational age window for aspirin prophylaxis implementation at the time of eligibility assessment.\n* Not receiving ongoing obstetric care at a participating site.",{"count":55,"type":20},1000,[23],"Preeclampsia is a leading cause of maternal morbidity and mortality. Low-dose aspirin prophylaxis reduces preeclampsia risk among high-risk pregnant individuals but remains underused in routine clinical practice. This pragmatic cluster-randomized implementation trial will test whether clinician notification of elevated preeclampsia risk increases aspirin prophylaxis utilization among eligible pregnant individuals receiving outpatient obstetric care.\n\nClusters will be randomized to clinician notification versus usual care. In the intervention arm, obstetric clinicians will receive notification that a patient is at elevated risk for preeclampsia and a recommendation to consider initiation of aspirin prophylaxis between 12 and 28 weeks' gestation, as clinically appropriate. The intervention does not assign participants to aspirin and does not require any study-mandated medication. All decisions regarding aspirin prophylaxis will remain at the discretion of the treating obstetric clinician and patient.",[27,28,59,60],"Pregnancy Complications","Aspirin Prophylaxis",[31,62],"aspirin prophylaxis","2026-05-22",{"date":65,"type":38},"2026-05-29",{"date":67,"type":20},"2027-05",{"date":69,"type":20},"2030-05",{"name":71,"class":45},"Massachusetts General Hospital",{"id":73,"slug":74,"hasResults":11,"nctId":75,"briefTitle":76,"officialTitle":77,"acronym":78,"eligibilityCriteria":79,"healthyVolunteers":11,"sex":16,"minAge":80,"maxAge":81,"enrollmentInfo":82,"targetDuration":4,"studyType":21,"phases":84,"briefSummary":85,"conditions":86,"keywords":90,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":97,"lastUpdatePostDateStruct":98,"startDateStruct":100,"completionDateStruct":102,"leadSponsor":104,"locationsCount":4},"100638145","community-support-and-mobile-apps-to-help-black-women-control-high-blood-pressure-after-pregnancy-100638145","NCT07606027","Community Support and Mobile Apps to Help Black Women Control High Blood Pressure After Pregnancy","Postpartum Remote Monitoring and Integration of Mobile Health With Engagement From Community Health Workers for Regulating Elevated Blood Pressure","PRIME CARE","Inclusion Criteria:\n\n* Black\u002F African American patients\n* Age: 19 and 50 years of age\n* Diagnosis: Hypertension Disorders of Pregnancy\n* Enrolled in STAMPP-HTN for first 6 weeks postpartum\n\nExclusion Criteria:\n\n* Age: \\\u003C19 years\n* Significant Kidney or Liver disease that may limit antihypertensive medication adjustment","19 Years","50 Years",{"count":83,"type":20},404,[23],"The goal of this randomized clinical trial is to evaluate the effectiveness of a collaborative care intervention, consisting of remote blood pressure monitoring and support from community health workers, in improving blood pressure control and reducing postpartum complications among Black women with hypertensive disorders of pregnancy (HDP). The primary objectives are to determine whether the intervention leads to improved blood pressure control at 12 months postpartum compared to standard care, and whether it reduces the incidence of serious maternal morbidity, including hospitalizations and cardiovascular events. Secondary objectives include examining whether patient activation and trust in the healthcare system mediate the relationship between the intervention and clinical outcomes. Participants will be enrolled at approximately 6 weeks postpartum and randomized to either the collaborative care intervention or standard postpartum care. All participants will self-monitor blood pressure using a provided device, receive guidance on hypertension management, and complete study assessments at multiple time points. Participants assigned to the intervention arm will additionally receive ongoing support from community health workers, including health education, care coordination, and assistance with healthcare navigation. Clinical outcomes and patient-reported measures will be assessed over a 12-month follow-up period.",[28,87,88,89],"Hypertension, Pregnancy Induced","Severe Maternal Morbidity","Postpartum Hypertension",[91,92,93,94,95,96],"Hypertension, Pregnancy-Induced","Postpartum Period","Remote Blood Pressure Monitoring","Community Health Workers","Postpartum Care","African American Women","2026-05-19",{"date":99,"type":38},"2026-05-26",{"date":101,"type":20},"2026-07-01",{"date":103,"type":20},"2031-06-30",{"name":105,"class":45},"University of Nebraska"]