[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"hyperthermic-intraperitoneal-chemotherapy-hipec\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:hyperthermic-intraperitoneal-chemotherapy-hipec":26},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":27,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":5},"100586964","hipec-surgery-and-hemodynamics-100586964",false,"NCT06922227","HIPEC Surgery and Hemodynamics","Perioperative Hemodynamic and Respiratory Changes During Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Combined With Cytoreductive Surgery","Inclusion Criteria:\n\n* ≥18 years old Patients planned to undergo cytoreductive surgery with hyperthermic intraperitoneal chemotherapy\n* ASA II-III-IV physical class\n\nExclusion Criteria:\n\n* \\\u003C18 years\n* Emergency cases","ALL","18 Years",{"count":19,"type":20},15,"ESTIMATED","OBSERVATIONAL","Hyperthermic Intraperitoneal Chemotherapy (HIPEC) involves the intraoperative administration of heated chemotherapeutic agents into the abdominal cavity following cytoreductive surgery (CRS). The increasing use of CRS combined with HIPEC has introduced certain procedural and physiological considerations that distinguish it from other surgical interventions, posing unique challenges for researchers and clinicians alike.\n\nDespite advancements in surgical and anesthetic techniques, this combined approach is frequently associated with significant hemodynamic instability, coagulation abnormalities, respiratory complications, and nutritional imbalances.\n\nThe study aims to contribute to the existing body of knowledge by examining the physiological alterations induced by HIPEC, thereby offering practical insights and guidance for investigators involved in the management and study of this complex therapeutic modality.",[24,25,26],"Hemodynamics","Cytoreductive Surgery","Hyperthermic Intraperitoneal Chemotherapy (HIPEC)",[28,29,24],"HİPEC","cytoreductive surgery","NOT_YET_RECRUITING","2025-04-10",{"date":33,"type":34},"2025-04-13","ACTUAL",{"date":36,"type":20},"2025-04-01",{"date":38,"type":20},"2025-07-15",{"name":40,"class":41},"Miray Gözde Özdemir","OTHER_GOV"]