[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"hypotensive-anesthesia\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:hypotensive-anesthesia":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,46],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100573944","phase-4-labetalol-infusion-and-dexmedetomidine-infusion-in-hypotensive-anesthesia-100573944",false,"NCT06752863","Labetalol Infusion and Dexmedetomidine Infusion in Hypotensive Anesthesia","Comparative Study of Labetalol Infusion Versus Dexmedetomidine Infusion in Hypotensive Anesthesia in Ear, Nose and Throat Surgeries","Inclusion Criteria:\n\n* American Society of Anesthesiologists I, II (ASA I, II) patients who were candidate for Ear, Nose and Throat surgeries.\n* Age: between 20 and 50 years\n\nExclusion Criteria:\n\n* Patients with uncontrolled hypertension, variable degrees of heart block, congestive cardiac failure, coagulopathy, cerebral insufficiency, hepatic or renal abnormality\n* Patients on beta blocker or clonidine\n* Pregnant or lactating females\n* Patients who were allergic to any of the anesthetic or hypotensive drugs used in the study\n* Patient refusal to be included in the trial","ALL","20 Years","50 Years",{"count":20,"type":21},80,"ESTIMATED","INTERVENTIONAL",[24],"PHASE4","this study aims to compare between the role of Labetalol infusion versus Dexmedetomidine infusion in hypotensive anesthesia in Ear, Nose and Throat surgeries.",[27,28],"Hypotensive Anesthesia","Ear, Nose and Throat Procedure",[30,31,32],"Hypotensive anesthesia","Labetalol","Dexmedetomidine","RECRUITING","2024-12-21",{"date":36,"type":37},"2024-12-31","ACTUAL",{"date":39,"type":37},"2024-11-27",{"date":41,"type":21},"2025-12",{"name":43,"class":44},"Ain Shams University","OTHER",1,{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":50,"acronym":4,"eligibilityCriteria":51,"healthyVolunteers":11,"sex":16,"minAge":52,"maxAge":18,"enrollmentInfo":53,"targetDuration":4,"studyType":22,"phases":55,"briefSummary":57,"conditions":58,"keywords":4,"overallStatus":64,"whyStopped":4,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":45},"100563809","pre-operative-phentolamine-vs-intraoperative-esmolol-efficacy-for-hypotensive-anesthesia-in-functional-endoscopic-sinus-surgery-100563809","NCT06620991","Pre-operative Phentolamine Vs Intraoperative Esmolol Efficacy for Hypotensive Anesthesia in Functional Endoscopic Sinus Surgery","Inclusion Criteria:\n\n* Age from 21 to 50 years.\n* Both sexes.\n* American Society of Anesthesiologists (ASA) physical status I-II.\n\nExclusion Criteria:\n\n* Patients with a medical condition that contraindicated hypotensive anesthesia, such as peripheral vascular disease, cerebrovascular stroke, carotid artery stenosis, previous myocardial infarction, ischemic heart disease, congestive heart failure, limb ischemia, uncontrolled hypertension and raised intracranial tension\n* Renal disease, liver dysfunction, pregnancy.\n* Patients on hypnotic or narcotic analgesic.\n* History of alcohol or drug abuse.\n* History of allergic reaction to any drug used in this study.\n* Bleeding diathesis.\n* Previous nasal surgery.\n* Patients on Non-steroidal anti-inflammatory drugs (NSAIDs).\n* Patients with peripheral vascular disease.","21 Years",{"count":54,"type":21},60,[56],"NA","The aim of this study is to evaluate the efficacy of intra-operative phentolamine vs intraoperative esmolol for hypotensive anesthesia in functional endoscopic sinus surgery.",[59,60,61,62,27,63],"Preoperative","Phentolamine","Intraoperative","Esmolol","Functional Endoscopic Sinus Surgery","NOT_YET_RECRUITING","2024-09-29",{"date":67,"type":37},"2024-10-01",{"date":69,"type":21},"2024-10-10",{"date":71,"type":21},"2025-04-01",{"name":43,"class":44}]