[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"hypothalamic-dysfunction\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:hypothalamic-dysfunction":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":25,"briefSummary":27,"conditions":28,"keywords":31,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":5},"100215456","reproductive-hormones-during-sustained-administration-of-kisspeptin-100215456",false,"NCT02081924","Reproductive Hormones During Sustained Administration of Kisspeptin","The Physiological Changes in Reproductive Hormones During Sustained Administration of Kisspeptin in Humans.","KisspeptPump","Inclusion criteria:\n\n* Aged 18-60 years old\n* Ability to give informed consent\n* Secondary hypogonadism (or healthy participant)\n\nExclusion criteria:\n\n* anaemia\n* medical problems such as severe heart, kidney or liver disease\n* blood donation in the last three months or intention to donate blood within 3 months of the end of the study\n* needle phobia\n* Poor venous access\n* Active psychiatric illness\n* Severe allergies\n* Impaired ability to provide full consent to take part in the study\n* Current alcohol or illicit drug dependence\n* Current pregnancy or breast feeding\n* Plans to conceive within 3 months of starting the study (barrier contraception must be used during and for 3 months after the end of the study)\n* Arthritis or any impairment of hand coordination which would preclude using a hormone pump",true,"ALL","18 Years","60 Years",{"count":22,"type":23},76,"ESTIMATED","INTERVENTIONAL",[26],"NA","We want to find out what happens to reproductive hormone levels; Luteinising Hormone (LH), Follicle Stimulating Hormone (FSH), testosterone and oestradiol when kisspeptin is administered to people for a period of 8 days each month, using either placebo (saline) or kisspeptin in doses of 0.1, 0.3 or 1.0 nmol\u002Fkg\u002Fhour.",[29,30],"Fertility Disorders","Hypothalamic Dysfunction",[32,33,34],"Infertility","Kisspeptin","Reproductive hormones","RECRUITING","2024-09-09",{"date":38,"type":39},"2024-09-19","ACTUAL",{"date":41,"type":39},"2014-04-02",{"date":43,"type":23},"2027-11-30",{"name":45,"class":46},"Imperial College London","OTHER"]