[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"hypoxia-in-healthy-individuals\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:hypoxia-in-healthy-individuals":32},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":25,"briefSummary":27,"conditions":28,"keywords":38,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":43,"lastUpdatePostDateStruct":44,"startDateStruct":47,"completionDateStruct":49,"leadSponsor":51,"locationsCount":5},"100638153","study-of-the-effects-of-acute-exposure-to-moderate-altitude-hypoxia-on-prospective-memory-100638153",false,"NCT07585227","Study of the Effects of Acute Exposure to Moderate Altitude Hypoxia on Prospective Memory.","Etude Des Effets d'Une Exposition aiguë à l'Hypoxie d'Altitude modérée Sur la mémoire Prospective (HYPRO)","HYPRO","Inclusion Criteria:\n\n* Healthy volunteer\n* Has provided informed consent\n\nExclusion Criteria:\n\n* Individuals who do not understand French\n* Pregnant or breastfeeding women\n* Cardiovascular risk factor\n* Infectious disease within the last 4 weeks\n* Chronic cardiovascular, respiratory, hematological, neurological, psychiatric, or metabolic disease\n* History of epileptic seizures, convulsions, or loss of consciousness\n* Individuals with migraines\n* History of a bleeding disorder\n* History of high blood pressure\n* Current medication use (excluding contraception)\n* History of episodes of altitude intolerance\n* Stay at high altitude (\\> 3,500 m) within the last 3 months\n* Anxiety score on the Hospital Anxiety and Depression (HAD) scale \\> 7\n* Depression score on the HAD scale \\> 7\n* Uncontrollable claustrophobia or a history of panic attacks",true,"ALL","18 Years","45 Years",{"count":22,"type":23},50,"ESTIMATED","INTERVENTIONAL",[26],"NA","The goal of this study is to investigate whether prospective memory, i.e., memory for delayed intentions, is impaired at moderate altitude (4,000m).\n\nIt will also allow to study the effect of air and oxygen administration during hypoxia exposure.\n\nThe main questions it aims to answer are:\n\n* Does moderate acute hypoxia impair prospective memory ?\n* If so, does air or oxygen adminsitration induce a restoration of prospective memory? Researchers will compare cognitive performance during normobaric hypoxia exposure to cognitive performance during normoxia (control situation).\n\nParticipants will:\n\n* Session S0. Perform a battery of neuropsychological tests and questionnaires). EEG will be recorded during tests. A cheek swab will be performed.\n* Sessions S1 and S2. Perform several cognitive tasks while exposed to hypoxia and to normoxia (2 different sessions, randomized order) in a normobaric chamber. These are standardized cognitive tests administered on a computer and cognitive tests embedded in a flight simulator scenario. Various questionnaires will be performed on a regular basis. Several physiological measurements will be performed continuously: EEG, ECG, SpO2 and breathing rate. Blood pressure will be measured at the beginning and at the end of hypoxia\u002Fnormoxia exposure. A blood sample will also be performed. At last, participants will inhale air or oxygen through a mask while making a cognitive task in the chamber.",[29,30,31,32,33,34,35,36,37],"Hypoxia","Hypoxia Brain","Hypoxia Altitude Simulation Test","Hypoxia in Healthy Individuals","Hypoxia, Altitude","Hypoxia, Brain","Altitude","Altitude Hypoxia","Normobaric Hypoxia",[39,40,41],"prospective memory","working memory","flight simulator","NOT_YET_RECRUITING","2026-05-09",{"date":45,"type":46},"2026-05-13","ACTUAL",{"date":48,"type":23},"2026-05-06",{"date":50,"type":23},"2026-12-31",{"name":52,"class":53},"Direction Centrale du Service de Santé des Armées","OTHER"]