[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"hypoxic-respiratory-failure\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:hypoxic-respiratory-failure":30},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,44,69],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":21,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":43},"100554594","optimizing-care-in-critically-ill-at-uchealth-by-liberalizing-the-target-o2-in-mechanically-ventilated-icu-patients-100554594",false,"NCT06501118","Optimizing Care in Critically Ill at UCHealth by Liberalizing the Target O2 in Mechanically-ventilated ICU Patients","Inclusion Criteria:\n\n* Admission to ICU and requiring invasive mechanical ventilation\n\nExclusion Criteria:\n\n* Transferred patients from outside the UCHealth system\\*:\n* Patients with pre-existing disease that requires chronic use of positive pressure ventilation delivered through a tracheostomy\\*:\n* Pregnant women:\n* Prisoners\n* Patients receiving mechanical ventilation for less than twelve hours","ALL","18 Years",{"count":18,"type":19},3600,"ESTIMATED","INTERVENTIONAL",[22],"NA","A multimodal educational intervention to target an oxygen saturation target range (SpO2 90-96%) will reduce ventilator length of stay and reduce occult hypoxemia by increased awareness and adherence to a designated oxygen saturation target range.",[25,26,27,28,29,30],"Respiratory Failure","Acute Hypoxemic Respiratory Failure","Acute Hypoxic Respiratory Failure","Hypoxemia","Hypoxia","Hypoxic Respiratory Failure","RECRUITING","2026-05-04",{"date":34,"type":35},"2026-05-08","ACTUAL",{"date":37,"type":35},"2024-09-01",{"date":39,"type":19},"2026-07-31",{"name":41,"class":42},"University of Colorado, Denver","OTHER",1,{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":50,"eligibilityCriteria":51,"healthyVolunteers":11,"sex":15,"minAge":4,"maxAge":52,"enrollmentInfo":53,"targetDuration":4,"studyType":55,"phases":4,"briefSummary":56,"conditions":57,"keywords":4,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":59,"lastUpdatePostDateStruct":60,"startDateStruct":62,"completionDateStruct":64,"leadSponsor":66,"locationsCount":43},"100600565","inhaled-nitric-oxide-for-the-treatment-of-neonatal-hypoxic-respiratory-failure-with-pulmonary-hypertension-100600565","NCT07099144","Inhaled Nitric Oxide for the Treatment of Neonatal Hypoxic Respiratory Failure With Pulmonary Hypertension","A Prospective, Open, Single-arm, Multi-center Phase IV Clinical Study of Inhaled Nitric Oxide Combined With Ventilatory Support for the Treatment of Neonatal (Gestational Age ≥34 Weeks) Hypoxic Respiratory Failure With Pulmonary Hypertension.","INOFTTONHRFWPH","Inclusion Criteria:\n\n1. Neonates ≥ 34 weeks gestation age.\n2. Hypoxic respiratory failure requiring more than 24 hours of ventilatory support.\n3. Clinical or echocardiographic evidence of pulmonary hypertension (systolic pulmonary arterial pressure \\[sPAP\\] \\> 35 mm Hg or \\> 2\u002F3 systemic blood pressure \\[SBP\\] or there is a right-to-left shunt at the atrium or arterial ductus).\n4. Age less than 7 days at the time of treatment initiation with study drug.\n5. The neonatal guardian agrees to participate in the study and signs an informed consent form (ICF).\n\nExclusion Criteria:\n\n1. Neonates dependent on right-to-left shunting of blood.\n2. Neonates whose mother has been treated with anticoagulant therapies during pregnancy.\n3. Echocardiography confirmed left-to-right shunt or left ventricular dysfunction.\n4. ECMO is urgently needed, or neonate has received ECMO.\n5. Patient is at risk of imminent death (death expected within 24 hours).\n6. Life-threatening abnormality (cranial, cardiac, thoracic).\n7. Chromosomal abnormality.\n8. Congenital diaphragmatic hernia\n9. Congenital heart defect (other than patent ductus arteriosus or small atrial septal defect).\n10. Neonate has been resuscitated requiring chest compressions within 6 hours of study treatment start.\n11. Significant bleeding diathesis such as grade IV intraventricular hemorrhage or periventricular leukomalacia, pulmonary hemorrhage, uncontrolled bleeding or hemodynamic failure.\n12. Disseminated intravascular coagulopathy.\n13. Active seizures while receiving anticonvulsants.\n14. Experienced prolong asphyxia with evidence of severe acidosis (pH\\\u003C7.25)\n15. Receiving nitric oxide donor agents such as prilocaine, sodium nitroprusside, nitroglycerin, and sulfonamides.\n16. Other subjects determined by the investigator to be unsuitable for inclusion.","7 Days",{"count":54,"type":19},120,"OBSERVATIONAL","This is a prospective, open-label, single-arm, multicenter Phase IV clinical study to evaluate the safety of INOmax for the treatment of hypoxic respiratory failure with pulmonary hypertension in newborns (≥ 34 weeks gestational age). To evaluate the safety of INOmax combined with ventilatory support in the treatment of neonatal (≥ 34 weeks gestational age) hypoxic respiratory failure with pulmonary hypertension.",[58,30],"Pulmonary Hypertension","2025-07-29",{"date":61,"type":35},"2025-08-01",{"date":63,"type":35},"2024-12-12",{"date":65,"type":19},"2026-12-30",{"name":67,"class":68},"Lee's Pharmaceutical Limited","INDUSTRY",{"id":70,"slug":71,"hasResults":11,"nctId":72,"briefTitle":73,"officialTitle":74,"acronym":4,"eligibilityCriteria":75,"healthyVolunteers":76,"sex":15,"minAge":16,"maxAge":77,"enrollmentInfo":78,"targetDuration":4,"studyType":20,"phases":80,"briefSummary":81,"conditions":82,"keywords":83,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":86,"startDateStruct":88,"completionDateStruct":90,"leadSponsor":92,"locationsCount":43},"100585337","effect-of-fast-hugs-with-icu-approach-on-length-of-intensive-care-unit-stay-in-patients-with-hypoxic-respiratory-failure-100585337","NCT06901050","Effect of FAST HUGS WITH ICU Approach on Length of Intensive Care Unit Stay in Patients With Hypoxic Respiratory Failure","Effect of FAST HUGS WITH ICU Approach on Length of Intensive Care Unit Stay in Patients With Hypoxic Respiratory Failure: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Being over 18 years old\n* Being in the Chest Intensive Care Unit\n* Having Hypoxic Respiratory Failure\n\nExclusion Criteria:\n\n* Death during hospitalization",true,"100 Years",{"count":79,"type":19},34,[22],"This study will investigate the effect of the FAST HUGS WITH ICU approach on the length of stay in the intensive care unit in patients with hypoxic respiratory failure. Patients will be randomly assigned to the experimental and control groups. The standard procedure will be applied to the control group. The FAST HUGS WITH ICU approach will be applied to the experimental group. We plan to follow up patients with Hypoxic Respiratory Failure using the abbreviation FAST HUGS WITH ICU (Feeding, Analgesia, Sedation, Thromboembolic prophylaxis, Head of bed elevation, Stress Ulcer prophylaxis and Glucose control Spontaneous breathing trial, Water Balance and constipation, Investigation and results, Therapy, Hypo-hyper delirium, Invasive devices, Check the daily infection parameters, Use a checlist). The two groups will be examined in terms of hospital stay and some blood gas parameters.",[30],[84],"Hypoxic respiratory failure","2025-03-23",{"date":87,"type":35},"2025-03-28",{"date":89,"type":35},"2024-12-01",{"date":91,"type":19},"2025-04-30",{"name":93,"class":42},"Muş Alparslan University"]