[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"ibd-and-renal-involement\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:ibd-and-renal-involement":27},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,51],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":50},"100639145","renal-dysfunction-in-patients-with-inflammatory-bowel-disease-and-the-general-population-nephro-ibd-100639145",false,"NCT07593352","Renal Dysfunction in Patients With Inflammatory Bowel Disease and the General Population (NEPHRO-IBD)","A Multicenter, Prospective, Observational Study Comparing the Prevalence of Renal Dysfunction in Adult Patient With Inflammatory Bowel Disease Between General Population: The NEPHRO-IBD Study.","NEPHRO-IBD","Inclusion Criteria:\n\n* Age over 18 years\n* Confirmed IBD based on the overall clinical picture and endoscopic examination, or no IBD (control group without IBD)\n* Consent to participate in the study\n* Cognitive abilities sufficient to complete the questionnaires\n\nExclusion Criteria:\n\n* diabetes\n* dysuric symptoms suggestive of urinary tract infections\n* in women, menstruation (urinalysis can be performed 3 days before the onset and 3 days after the end of menstruation)\n* refusal to participate in all procedures performed in the study\n* age under 18 or over 80\n* pregnancy\n* other serious comorbidities whose presence or exacerbation may cause abnormalities in laboratory tests suggesting kidney disease\n* previous surgery whose presence may cause abnormalities in laboratory tests suggesting kidney disease\n* extreme physical exertion within 7 days before the test (marathons, half-marathons, triathlons) and intense physical exertion - strength training - within 1 day before the test. \\[moderate physical exertion such as walking, swimming, or cycling is not a contraindication\\]. • Excessive alcohol consumption 14 days before the study\n* Inability to perform necessary tests: e.g., inability to perform an imaging test\n* Unavailability of data: if the study is based on registry data, exclusion of individuals for whom there is incomplete data\n* Dehydration\n* Use of nephrotoxic medications\\* within a month before and during the study\n* Use of angiotensin inhibitors, sartans, or flozins that were introduced into treatment within \\\u003C3 months\n\n  \\*Nephrotoxic drugs:\n* Nonsteroidal anti-inflammatory drugs (NSAIDs) - occasional use is not contraindicated, but use for ≥ 10 days is an exclusion criterion\n* Gold salts\n* Penicillamine\n* Interferon alpha\n* Antituberculosis drugs (rifampicin, ethambutol, isoniazid)\n* Pamidronate\n* Biseptol\n* Antiviral drugs (acyclovir)\n* Anticonvulsants (carbamazepine, diazepam, phenobarbital)\n* Cyclosporine A, tacrolimus\n* Chinese herbs\n* Oncology drugs (cisplatin)",true,"ALL","18 Years","80 Years",{"count":22,"type":23},6000,"ESTIMATED","OBSERVATIONAL","The NEPHRO-IBD study is a multicenter prospective observational study designed to evaluate the prevalence of renal dysfunction and renal complications in adult patients with inflammatory bowel disease (IBD) compared with individuals from the general population. Although extraintestinal manifestations are common in IBD, renal involvement remains relatively underrecognized and insufficiently studied.\n\nThe study will recruit approximately 6,000 participants, including 3,000 patients with confirmed IBD (Crohn's disease or ulcerative colitis) and 3,000 individuals without IBD serving as a control group. Participants will undergo routine clinical assessment, including laboratory tests, urinalysis with measurement of the albumin-to-creatinine ratio (ACR), and imaging evaluation of the kidneys and urinary tract. Disease activity in patients with IBD will be assessed using validated clinical indices.\n\nThe study will also evaluate the relationship between renal dysfunction and disease activity, medications used in IBD treatment, and comorbidities. The results of this study are expected to improve the understanding of renal complications in patients with IBD and support earlier identification and management of kidney disease in this population.",[27,28,29],"IBD and Renal Involement","Chronic Kidney Disease","Inflamatory Bowel Disease (Crohn's and Ulcerative Colitis)",[31,32,33,34,28,35,36,37],"IBD","Crohn's Disease","Ulcerative Colitis","Renal Dysfunction","Extraintestinal Manifestations","Renal Complications in IBD","Albumin-to-Creatinine Ratio","RECRUITING","2026-05-13",{"date":41,"type":42},"2026-05-18","ACTUAL",{"date":44,"type":42},"2025-11-20",{"date":46,"type":23},"2026-12-30",{"name":48,"class":49},"Państwowy Instytut Medyczny Ministerstwa Spraw Wewnętrznych i Administracji","OTHER_GOV",1,{"id":52,"slug":53,"hasResults":11,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":4,"eligibilityCriteria":57,"healthyVolunteers":11,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":58,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":60,"conditions":61,"keywords":63,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":4},"100571228","renal-involvement-in-adult-patients-with-inflammatory-bowel-disease-and-its-relation-to-duration-and-disease-activity-100571228","NCT06717516","Renal Involvement in Adult Patients With Inflammatory Bowel Disease and Its Relation to Duration and Disease Activity","Renal Involvement in Adult Patients With Inflammatory Bowel Disease and Its Relation to Duration and Disease Activity .","Inclusion Criteria:\n\n* Adults aged 18 years or older\n* Confirmed diagnosis of IBD either crohns disease or ulcerative colities based on clinical ,endoscopic ,histological and radiological findings . - Patients in any stage of IBD, including remission, active disease, and flare-ups. - Willingness to participate and provide informed consent. - Renal Assessment for participants.\n\nExclusion Criteria:\n\n\\- Pre-existing chronic kidney disease (CKD) at any stage. - Known primary kidney diseases unrelated to IBD. - Current use of nephrotoxic medications not related to IBD treatment. - Pregnancy or breastfeeding. - Patients who are unable to comply with study protocols or follow-up assessment - Presence of other significant comorbidities that impact renal function or overall health",{"count":59,"type":23},100,"To Assess the pattern of renal injury in patients with inflammatory bowel disease and its relation to the duration and disease activity by Identification and characterization of early renal manifestations (e.g., proteinuria, hematuria, electrolyte imbalances) in IBD patients. and know Correlation between kidney involvement and IBD severity, including flare-ups and complications.\n\nand know Impact of early renal manifestations on long-term renal outcomes, such as progression to CKD or development of AKI.",[27,62],"IBD Activity and Kidney Affection",[64],"IBD and kidney","NOT_YET_RECRUITING","2024-11-30",{"date":68,"type":42},"2024-12-05",{"date":70,"type":23},"2024-12-01",{"date":72,"type":23},"2026-01",{"name":74,"class":75},"Assiut University","OTHER"]