[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"conditionNormalized\":\"ictus\",\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:ictus":25},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,51,80],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":28,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":39,"lastUpdatePostDateStruct":40,"startDateStruct":43,"completionDateStruct":45,"leadSponsor":47,"locationsCount":50},"100602155","personality-traits-as-a-variable-in-the-recovery-of-patients-with-acquired-brain-injury-100602155",false,"NCT07119827","Personality Traits as a Variable in the Recovery of Patients With Acquired Brain Injury","Neuropsychology and Personality: Personality Traits as a Variable in the Recovery of Patients With Acquired Brain Injury","Inclusion Criteria:\n\n* diagnosis of one of the following two conditions:\n* Severe Acquired Brain Injury (sABI) of traumatic or non-traumatic etiology; the term sABI includes acute brain injuries of traumatic or non-traumatic origin (vascular, infectious, metabolic, or anoxic), in which the patient initially presents with a coma state (Glasgow Coma Scale - GCS less than 8) and simultaneously exhibits motor, sensory, cognitive, and\u002For behavioral impairments.\n* Ischemic or hemorrhagic stroke without features of Severe Acquired Brain Injury (sABI) (Glasgow Coma Scale \\[GCS\\] score ≥ 8 and no alteration of consciousness).\n* Time from injury between:\n* 7 and 90 days for Severe Acquired Brain Injury (sABI) patients\n* 3 and 30 days for stroke patients\n* Level of Cognitive Functioning (LCF) score ≥ 6 for sABI patients\n* Signed informed consent for study participation\n* Presence of a support family member (caregiver) able to assist with completing the personality questionnaire (HEXACO Adjective Scale, HAS)\n\nExclusion Criteria:\n\n* Pre-existing neurological pathology\n* Severe aphasia or severe inattention that precludes administration of the tests required by the protocol, as identified during cognitive screening.\n* Patients with a language barrier due to insufficient proficiency in Italian.\n* Particularly vulnerable populations:\n\nThe following patients will be excluded from the study: patients in emergency situations.","ALL","18 Years","80 Years",{"count":20,"type":21},250,"ESTIMATED","OBSERVATIONAL","This study aims to evaluate the potential effects of premorbid personality on the short- and long-term global cognitive recovery in patients with severe acquired brain injury (sABI) or stroke.\n\nThe secondary aims are to assess the effects of premorbid personality on the sort- and long-term recovery in autonomy (disability), cognitive functions, psycho-behavioral functioning, motor skills, and social participation. Evaluate the incidence of premorbid personality alterations. Investigate personality changes 12-18 months after the neurological event.",[25,26,27],"Ictus","Severe Acquired Brain Injury","sABI",[29,30,31,32,33,34,35,36,37,27],"premorbid personality","stroke","severe acquired brain injury","recovery","cognitive deficits","motor deficits","disability","psychological functioning","behaviour","RECRUITING","2026-06-29",{"date":41,"type":42},"2026-07-02","ACTUAL",{"date":44,"type":42},"2025-05-01",{"date":46,"type":21},"2028-05-01",{"name":48,"class":49},"Universita di Verona","OTHER",1,{"id":52,"slug":53,"hasResults":11,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":4,"eligibilityCriteria":57,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":58,"enrollmentInfo":59,"targetDuration":4,"studyType":61,"phases":62,"briefSummary":64,"conditions":65,"keywords":67,"overallStatus":38,"whyStopped":4,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":50},"100608078","percutaneous-ultrasound-guided-neuromodulation-to-improve-gait-rehabilitation-in-patients-who-have-suffered-a-stroke-100608078","NCT07196878","Percutaneous Ultrasound-guided Neuromodulation to Improve Gait Rehabilitation in Patients Who Have Suffered a Stroke.","Ultrasound-Guided Percutaneous Neuromodulation Protocol to Improve Gait Rehabilitation in Patients Who Have Suffered a Stroke. Clinical Trial.","Inclusion Criteria:\n\n1. Be between 18 and 70 years of age;\n2. Have suffered a stroke (CVA);\n3. Be in the subacute or chronic phase of the disease;\n4. Be able to walk 10 meters without assistance from another person;\n5. Currently be undergoing physiotherapy with conservative techniques;\n6. Be able to understand the technique being applied;\n7. Sign the informed consent form.\n\nExclusion Criteria:\n\n1. Belonephobia (fear of needles);\n2. Allergy to needles or metals;\n3. Presence of uncontrolled coagulopathies;\n4. Presence of uncontrolled arterial disease;\n5. Pregnancy;\n6. Dermatological disorders;\n7. Presence of diseases such as systemic inflammatory disorders (e.g., rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, or septic arthritis);\n8. Presence of diseases such as tumors, cancer, or metastases;\n9. Having received invasive physiotherapy treatment in the last 4 weeks.","70 Years",{"count":60,"type":21},30,"INTERVENTIONAL",[63],"NA","The goal of this clinical trial is to learn if percutaneous ultrasound-guided neuromodulation (NMP-e) can improve gait rehabilitation in adults who have suffered a stroke. The main questions it aims to answer are:\n\n* Does NMP-e improve walking speed in stroke survivors?\n* Does NMP-e enhance muscle strength, functional mobility, reduce spasticity, improve balance, and increase health-related quality of life?\n\nResearchers will compare the addition of NMP-e to conventional physiotherapy versus conventional physiotherapy alone to see if the intervention provides additional benefits in gait rehabilitation and other functional outcomes.\n\nParticipants will:\n\n* Continue their regular physiotherapy treatment consisting of passive and active-assisted mobilizations and strength exercises.\n* Receive NMP-e targeting the sciatic nerve at mid-thigh and the common peroneal nerve at the fibular head (experimental group only).\n* Undergo stimulation with an electrostimulator at 10 Hz for 10 seconds per trial, repeated 10 times, with intensity adjusted for comfort.\n* Be evaluated before the intervention, immediately after, and one week later using:\n* 10-Meter Walk Test for gait speed\n* Dynamometry for ankle plantarflexor and dorsiflexor strength\n* Time Up and Go test for functional mobility\n* Modified Modified Ashworth Scale for spasticity\n* Berg Balance Scale for balance\n* EuroQoL-5 Dimensions for health-related quality of life\n\nParticipants must be adults aged 18-70, able to walk 10 meters without assistance, currently receiving physiotherapy, and able to provide informed consent. Key exclusions include pregnancy, bleeding disorders, needle allergies, systemic inflammatory disorders, or recent invasive physiotherapy.\n\nThis randomized controlled trial will be conducted at ATECE, \\*\\*a Spanish association dedicated to the care and rehabilitation of individuals with acquired brain injury\\*\\*, where participants will be recruited and receive their interventions. The study aims to evaluate the potential of NMP-e as an adjunctive therapy for improving gait and related functional outcomes in subacute and chronic stroke patients.",[25,66],"Gait Disorders, Neurologic",[68,69,70],"ICTUS","Gait disorder","Ultrasound guided neuromodulation","2026-06-10",{"date":73,"type":42},"2026-06-12",{"date":75,"type":42},"2025-09-15",{"date":77,"type":21},"2026-12-31",{"name":79,"class":49},"Alejandro Martín García",{"id":81,"slug":82,"hasResults":11,"nctId":83,"briefTitle":84,"officialTitle":85,"acronym":86,"eligibilityCriteria":87,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":88,"targetDuration":4,"studyType":61,"phases":90,"briefSummary":91,"conditions":92,"keywords":95,"overallStatus":100,"whyStopped":4,"lastUpdateSubmitDate":101,"lastUpdatePostDateStruct":102,"startDateStruct":104,"completionDateStruct":106,"leadSponsor":108,"locationsCount":50},"100640969","motor-and-cognitive-telerehabilitation-in-a-virtual-environment-in-patients-with-post-stroke-sequelae-and-parkinsons-disease-100640969","NCT07582497","Motor and Cognitive Telerehabilitation in a Virtual Environment in Patients With Post-stroke Sequelae and Parkinson's Disease","Telerehabilitation in a Virtual Environment for Sensorimotor and Cognitive Recovery in Patients With Post-stroke Sequelae and Parkinson's Disease: a Pilot Study","HOME VR REHAB","Inclusion Criteria:\n\n* Age \\>18 years old, both sex;\n* stroke or Parkinson diagnosis \\> or = 2 months;\n* upper limb impairment\n* informed consent signed\n\nExclusion Criteria:\n\n* ongoing clinical instability;\n* important cognitive impairment;\n* psychiatric, neurological, or internal medicine comorbidities;\n* severe rigidity or hypertonia;\n* severe visual deficit;\n* pregnancy women",{"count":89,"type":21},60,[63],"The goal of this interventional pilot trial is to evaluate whether a telerehabilitation protocol based on immersive virtual reality (VR) is effective and feasible for the recovery of cognitive and\u002For motor functions in patients with sequelae of ischemic or hemorrhagic stroke or with Parkinson's disease.\n\nThe main questions it aims to answer are:\n\n* Does the VR-based telerehabilitation protocol improve cognitive and\u002For motor outcomes compared to conventional rehabilitation?\n* Is the protocol feasible, defined as ≥80% adherence among participants? Is the system acceptable and user-friendly from the patient's perspective? Researchers will compare an interventional arm receiving telerehabilitation via an immersive VR home kit with a control arm receiving conventional rehabilitation according to standard clinical practice. Both groups will receive the same number of sessions, with the same duration and weekly frequency. Outcomes will be assessed at baseline (T0), after 4 weeks of treatment (T1), and at 3-month follow-up (T2).",[25,93,94],"Stroke","Parkinson Disease",[96,97,98,99],"upper limb impairment","teleneurorehabilitation","virtual reality","telerehabilitation","NOT_YET_RECRUITING","2026-05-12",{"date":103,"type":42},"2026-05-14",{"date":105,"type":21},"2026-06",{"date":107,"type":21},"2026-12",{"name":109,"class":110},"Azienda Usl di Bologna","OTHER_GOV"]